resveratrol has been researched along with Cancer of Lung in 113 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (0.88) | 18.2507 |
| 2000's | 15 (13.27) | 29.6817 |
| 2010's | 74 (65.49) | 24.3611 |
| 2020's | 23 (20.35) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, XY; Dai, F; Hu, LM; Jin, XL; Kang, YF; Li, XZ; Li, Y; Liu, GY; Tang, JJ; Yang, J; Zhou, B | 1 |
| Gao, P; Ren, G | 1 |
| Bian, Y; Li, G; Qiao, M; Ren, G; Wang, X; Zheng, Z; Zhu, H | 1 |
| Chang, Q; Chen, J; Hao, Z; Li, J; Liang, P; Lu, J; Shi, J; Zeng, Z | 1 |
| Fan, Y; Li, J; Liu, Y; Ma, M; Yu, Y; Zhang, Y | 1 |
| Abbaspour-Ravasjani, S; Asadollahi, L; Dorreyatim, SS; Hamishehkar, H; Mahoutforoush, A; Paiva-Santos, AC; Peixoto, D; Soltanfam, T; Veiga, F; Zeinali, M | 1 |
| Cao, YH; Fu, D; Huang, ZY; Jiang, GX; Li, CG; Li, S; Li, W; Liu, JB; Ma, YS; Shen, B; Xin, R; Zhang, J; Zou, DZ | 1 |
| Chen, Y; Li, X; Liang, C; Miao, D; Wang, R; Xie, C; Yi, K; Zhong, C; Zhou, X; Zhu, J | 1 |
| Chanvorachote, P; Chaotham, C; Innets, B; Moriue, S; Petsri, K; Racha, S; Thongsom, S; Yokoya, M | 1 |
| Cao, H; Li, X; Liang, C; Xie, C; Yi, K; Zhong, C; Zhou, X; Zhu, J | 1 |
| Guangjian, Z; Jin, Z; Jizhao, W; Meihe, L; Minchao, K; Rui, Z; Shan, G | 1 |
| Al Hroot, J; Al-Husein, B; Mayyas, A; Zayed, A | 1 |
| Jia, ML; Liu, SY; Liu, W; Yang, H; Zeng, XF; Zhang, W; Zhu, WT | 1 |
| Chanvorachote, P; Ei, ZZ; Moriue, S; Petsri, K; Racha, S; Thongsom, S; Visuttijai, K; Yokoya, M | 1 |
| Chen, QQ; Guo, JR; Lam, CWK; Li, Z; Wang, CY; Wong, VKW; Yao, MC; Zhang, W; Zhang, WJ | 1 |
| Li, Y; Liu, X; Long, Y; Yang, Y; Zheng, Y | 1 |
| Bozok Cetintas, V; Duzgun, Z; Erdem, C; Eroglu, Z; Oktem, G | 1 |
| Gupta, V; Kanabar, DD; Muth, A; Parvathaneni, V; Shukla, SK; Wang, X | 1 |
| Gupta, V; Kulkarni, NS; Kunda, NK; Muth, A; Parvathaneni, V; Shukla, SK; Wang, X | 1 |
| Jin, F; Li, C; Li, W; Ma, L | 1 |
| Borran, S; Darvish, M; Davoodvandi, A; Hamblin, MR; Masoudian, N; Mazaheri, S; Mirzaei, H; Nejati, M; Reza Tamtaji, O | 1 |
| Cheng, Y; Fan, Y; Feng, Y; Jiang, Y; Li, J; Liu, Y; Yang, Y; Yu, Y; Zhao, X; Zhou, L | 1 |
| Cheng, F; Hu, H; Li, Z; Sun, Y; Tao, J; Wei, H; Wu, Z; Yang, J; Yang, M; Zhang, Y; Zhang, Z | 1 |
| Bobak, K; Chodyński, M; Gos, M; Kutner, A; Maj, B; Maj, E; Wietrzyk, J | 1 |
| Bi, JJ; Chen, QG; Lin, YH; Luo, XM; Ni, ZH; Sun, YP; Wang, XB; Yang, YQ; Zhang, ZH; Zhu, LY | 1 |
| Han, X; Liu, B; Teng, Y; Wang, J; Zhao, N; Zhu, W | 1 |
| Fan, F; Gao, C; He, L; Hou, X; Huang, S; Meng, L; Meng, S; Wu, H | 1 |
| Du, J; Li, C; Liu, Y; Wang, L; Wang, Y; Zhao, J; Zhou, Y | 1 |
| Tsiani, E; Vlachogiannis, IA; Yousef, M | 1 |
| Atwi, D; Banerjee, P; Fried, A; Hussaini, R; Mukherjee, S; Pan, Q; Piao, L; Sampat, S; White, R | 1 |
| Dai, G; Han, Q; Shi, Y; Song, Z | 1 |
| Du, L; He, N; Ji, K; Liu, Q; Liu, Y; Sun, X; Wang, J; Wang, Y; Xu, C | 1 |
| Jeong, JK; Park, SY; Rasheduzzaman, M | 1 |
| Jin, F; Li, W; Ma, L; Pan, L; Shi, Y; Wang, R | 1 |
| Allémann, E; Cuendet, M; Furrer, P; Monteillier, A; Voisin, A | 1 |
| Banegas, YC; Córdoba, EE; Fernández, E; Güerci, AM; Ocolotobiche, EE; Padula, G | 1 |
| He, B; Lin, L; Liu, D; Malhotra, A; Yuan, N | 1 |
| Bhatia, D; Shi, Q | 1 |
| Abdelaziz, HM; Elzoghby, AO; Fang, JY; Freag, MS; Helmy, MW; Samaha, MW | 1 |
| Chang, MC; Chang, YC; Chen, CC; Chen, KY | 1 |
| Luo, H; Schulte, BA; Wang, GY; Wargovich, MJ; Yang, A | 1 |
| Guan, L; Huang, XE; Tian, QZ; Yin, HT; Zhang, H; Zhou, Y | 1 |
| Chen, C; Jiang, X; Zhang, Z; Zhao, W | 1 |
| Chen, HJ; Chen, RS; Chiu, HC; Huang, YC; Huang, YJ; Jian, YJ; Ko, JC; Lee, WT; Lin, YW; Tseng, SC; Wo, TY | 1 |
| Biragyn, A; Bodogai, M; de Cabo, R; Lee-Chang, C; Martin-Montalvo, A; Moaddel, R; Sanghvi, M; Wejksza, K | 1 |
| Luo, H; Schulte, BA; Tang, S; Wang, GY; Wang, L; Yang, A | 1 |
| Celik, S; Gunay, E; Hazman, O; Koyuncu, T; Ozdemir, M; Ozyurek, A; Ulasli, SS; Unlu, M | 1 |
| Bai, T; Dong, DS; Pei, L | 1 |
| Dhawan, DK; Malhotra, A; Nair, P | 5 |
| Choi, YJ; Hwang, IS; Kim, SH; Lee, CH; Lee, SH; Lee, YJ; Nam, HS | 1 |
| Chen, C; Gu, S; Jiang, X; Zhang, Z | 3 |
| Chiu, JF; Li, G; Ma, K; Qi, T; Wei, X; Zhang, J; Zhang, Q | 1 |
| Chien, MH; Hsiao, M; Hsieh, FK; Lee, WJ; Tan, P; Tang, CH; Yang, SF | 1 |
| Cao, CS; Li, K; Liu, Y; Wu, YM; Yu, Y; Zhang, JH; Zhang, PY | 1 |
| Chu, L; Ding, M; Huang, W; Li, H; Liu, XY; Xiao, J; Xu, H; Yang, D; Yang, Y | 1 |
| Hoti, SL; Karthikeyan, S; Prasad, NR | 1 |
| Dai, J; Han, Z; Jiang, Y; Liu, B; Peng, B; Wu, J; Xu, E; Yang, Q; Zhang, S; Zhang, Y | 1 |
| Hou, B; Hu, W; Nie, P; Yang, Y; Zhang, T; Zou, Z | 1 |
| Dong, HM; Hong, T; Jiang, W; Lu, Y; Qiu, SX | 1 |
| Chang, PY; Chen, CY; Chen, JC; Jian, YJ; Jian, YT; Ko, JC; Lin, YW; Syu, JJ; Wang, TJ | 1 |
| Kolodziej, H; Lucas, IK | 1 |
| Jin, F; Li, W; Liu, W; Ma, L; Nan, Y; Wang, Q; Wang, R | 1 |
| Baycu, C; Bektur, E; Burukoglu Donmez, D; Koparal, AT; Sahin, E | 1 |
| Bianchi, L; Cao, Y; Corana, F; Ferraro, D; Jensen, LD; Maccario, C; Mannucci, B; Savio, M; Stivala, LA; Vaccarone, R | 1 |
| Hu, S; Kong, H; Li, X; Wang, H; Xie, W; Xu, R; Ye, L; Zeng, X | 1 |
| Wang, D; Wang, X; Zhao, Y | 1 |
| Cho, MK; Heo, SH; Lee, GJ; Lee, SH; Lee, YJ; Nam, HS; Park, CR; Yi, SS | 1 |
| Jeong, JH; Kim, WY; Kim, Y; Lee, H; Ryu, JH | 1 |
| Chen, B; Jiang, R; Li, J; Sun, L; Wang, B | 1 |
| Dong, Q; Li, N; Li, W; Liang, Q; Liu, H; Liu, Y; Ma, X; Rong, P; Song, W; Tan, S; Wang, W; Xu, C; Yang, C; Zhang, J; Zhang, S | 1 |
| Bjørklund, G; Chirumbolo, S | 1 |
| Chen, J; Li, X; Shi, T; Wang, D; Zhao, QC | 1 |
| Hu, LL; Li, ZP; Liu, J; Wang, AW; Wang, ZD; Zhao, QS | 1 |
| Azad, N; Iyer, AKV; Wright, C; Yakisich, JS | 1 |
| Kamholz, SL | 1 |
| Ho, CT; Weng, CJ; Yang, YT; Yen, GC | 1 |
| Chang, JC; Chiou, RY; Li, AF; Liao, HF; Weng, YL | 1 |
| Han, Y; He, D; Jin, S; Qi, F; Wang, J; Zhang, Q | 1 |
| Charles, AL; Chen, WC; Chen, YH; Chen, YL; Chong, IW; Chou, SH; Hung, CY; Hwang, JJ; Lin, FY; Liu, PL; Ping, YH; Tsai, JR | 1 |
| Chen, Z; Gao, L; Jin, K; Jin, Y; Lou, G; Lou, Y; Yu, Y | 1 |
| Chang, L; Huang, N; Li, G; Lu, H; Zhang, H | 1 |
| Chen, T; Wang, X; Zhang, W | 2 |
| Ju, RJ; Li, RJ; Li, YB; Lu, WL; Wang, XX; Yao, HJ; Yu, Y; Zhang, L; Zhang, Y | 1 |
| An, S; Bae, S; Cha, HJ; Jeung, HK; Kim, J; Kim, K; Kim, YJ; Lee, EM; Lee, H; Lee, HG; Min, YH; Yoon, Y | 1 |
| Han, Z; Jiang, Y; Li, Y; Liu, B; Wu, J; Yang, C; Yang, Q | 1 |
| Chang, TY; Chang, YW; Chen, CY; Chen, HA; Chen, PS; Chen, YH; Cheng, YJ; Chien, MH; Hsiao, M; Hsu, WH; Huang, MT; Hung, MC; Jan, Y; Jeng, YM; Kuo, ML; Liu, YH; Su, JL; Su, YH; Wu, CH; Yu, YH | 1 |
| Guan, H; Nagarkatti, M; Nagarkatti, PS; Singh, NP; Singh, UP | 1 |
| Chen, T; Li, H; Qu, J; Wang, X | 1 |
| Kim, YS; Sull, JW; Sung, HJ | 1 |
| Hou, Q; Meng, AM; Shi, J | 1 |
| Bishayee, A; Blanco, D; Booth, TD; Marcanthony, S; Sloan, T; Stakleff, KS | 1 |
| Chen, H; Chen, X; Liu, G; Tang, L; Wang, H; Wu, C; Yang, Y; Zhang, H; Zhao, M | 1 |
| Casanova, FA; Dos Santos, PS; Ferraz da Costa, DC; Fialho, E; Malheiros, MS; Quarti, J; Sanches, D; Silva, JL | 1 |
| Hoe, YH; Kim, EY; Kim, S; Ko, H; Lee, SK; Lee, T; Min, HY; Nam, KA; Song, S | 1 |
| Han, W; Pentecost, BT; Spivack, SD | 1 |
| Berge, G; Eilertsen, E; Haugen, A; Mollerup, S; Øvrebø, S | 1 |
| Cook, CP; Fu, YM; McLaughlin, JL; Meadows, GG; Niles, RM; Rankin, GO | 1 |
| Becker, K; Hu, Y; Mersch-Sundermann, V; Rahlfs, S | 1 |
| El-Naggar, AK; Gaur, A; Kondo, S; Kumar, R; Ohshiro, K; Rayala, SK; Vadlamudi, RK | 1 |
| Huang, YY; Mehta, RG; Torres, K; Whyte, L | 1 |
| Binda, O; Branton, PE; Nassif, C | 1 |
| Agarwal, S; Hecht, SS; Kenney, PM; Rao, AV; Trushin, N; Upadhyaya, P; Wang, M | 1 |
| Aiello, FB; Brunetti, M; Caltagirone, S; Natali, PG; Piantelli, M; Poggi, A; Ranelletti, FO; Rossi, C | 1 |
| Fischer, H; Illek, B; Kurth, MJ; Lee, V; Lizarzaburu, ME; Nantz, MH | 1 |
| Haugen, A; Mollerup, S; Ovrebø, S | 1 |
| Kimura, Y; Okuda, H | 1 |
4 review(s) available for resveratrol and Cancer of Lung
| Article | Year |
|---|---|
Research Progress in Elucidating the Mechanisms Underlying Resveratrol Action on Lung Cancer.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Lung Neoplasms; Male; Resveratrol; Signal Transduction; Stilbenes | 2023 |
Effects of Resveratrol against Lung Cancer: In Vitro and In Vivo Studies.
Topics: Cell Line, Tumor; Cell Survival; Humans; Lung Neoplasms; Resveratrol; Stilbenes | 2017 |
Wine, spirits and the lung: good, bad or indifferent?
Topics: Adenocarcinoma; Alcohol Drinking; Alcoholic Beverages; Alcoholism; Altitude Sickness; Antioxidants; Asthma; Female; Humans; Lung; Lung Neoplasms; Male; Pulmonary Disease, Chronic Obstructive; Pulmonary Edema; Respiratory Distress Syndrome; Resveratrol; Stilbenes; Sulfites; Wine | 2006 |
[Sirtuin1 and lung disease].
Topics: Animals; Asthma; Benzamides; Humans; Lung Diseases; Lung Neoplasms; Naphthols; Protein Processing, Post-Translational; Pulmonary Disease, Chronic Obstructive; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
109 other study(ies) available for resveratrol and Cancer of Lung
| Article | Year |
|---|---|
Synthesis and biological evaluation of hydroxylated 3-phenylcoumarins as antioxidants and antiproliferative agents.
Topics: Adenocarcinoma; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Coumarins; DNA Damage; Drug Evaluation, Preclinical; Humans; Lung Neoplasms; Structure-Activity Relationship | 2011 |
Identification of potential target genes of non-small cell lung cancer in response to resveratrol treatment by bioinformatics analysis.
Topics: A549 Cells; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; CD13 Antigens; Computational Biology; Databases, Genetic; Humans; Lung Neoplasms; Protein Interaction Maps; Resveratrol; Signal Transduction | 2021 |
Resveratrol drives cancer cell senescence
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cellular Senescence; DNA Damage; Endoplasmic Reticulum Stress; GTPase-Activating Proteins; Humans; Lung Neoplasms; MAP Kinase Signaling System; MCF-7 Cells; Mitochondria; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Resveratrol; Signal Transduction; Sirtuin 1; Tumor Suppressor Proteins; Up-Regulation | 2022 |
Immunoprognostic model of lung adenocarcinoma and screening of sensitive drugs.
Topics: Adenocarcinoma; Carrier Proteins; Histocompatibility Antigens Class I; Humans; Lung; Lung Neoplasms; Male; Membrane Proteins; Methotrexate; Phenoxybenzamine; Resveratrol; RNA, Long Noncoding; RNA, Messenger; Tumor Microenvironment | 2022 |
Resveratrol Induces Autophagy and Apoptosis in Non-Small-Cell Lung Cancer Cells by Activating the NGFR-AMPK-mTOR Pathway.
Topics: AMP-Activated Protein Kinases; Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Humans; Lung Neoplasms; Nerve Tissue Proteins; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Resveratrol; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases | 2022 |
Co-Delivery of erlotinib and resveratrol via nanostructured lipid Carriers: A synergistically promising approach for cell proliferation prevention and ROS-Mediated apoptosis activation.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Drug Carriers; Erlotinib Hydrochloride; Humans; Lipids; Lung Neoplasms; Nanostructures; Particle Size; Reactive Oxygen Species; Resveratrol | 2022 |
Resveratrol suppresses lung cancer by targeting cancer stem-like cells and regulating tumor microenvironment.
Topics: beta Catenin; Cell Line, Tumor; Cell Proliferation; Humans; Interleukin-6; Lung Neoplasms; Neoplastic Stem Cells; Resveratrol; Tumor Microenvironment; Wnt Signaling Pathway | 2023 |
Akt/mTOR Targeting Activity of Resveratrol Derivatives in Non-Small Lung Cancer.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Molecular Docking Simulation; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; TOR Serine-Threonine Kinases | 2022 |
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Topics: Antioxidants; Apoptosis; Cell Line, Tumor; Cellular Senescence; Humans; Lung Neoplasms; NF-E2-Related Factor 2; Reactive Oxygen Species; Resveratrol | 2023 |
Resveratrol improves the cytotoxic effect of CD8 +T cells in the tumor microenvironment by regulating HMMR/Ferroptosis in lung squamous cell carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; CD8-Positive T-Lymphocytes; Ferroptosis; Humans; Lung; Lung Neoplasms; Resveratrol; Tumor Microenvironment | 2023 |
Rapid high performance liquid chromatography method for erlotinib quantification in vitro: Application to study the effect of resveratrol on metabolism and cellular uptake of erlotinib.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Erlotinib Hydrochloride; Humans; Lung Neoplasms; Microsomes, Liver; Rats; Resveratrol | 2023 |
Resveratrol Loaded by Folate-Modified Liposomes Inhibits Osteosarcoma Growth and Lung Metastasis via Regulating JAK2/STAT3 Pathway.
Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Folic Acid; Humans; Janus Kinase 2; Lipopolysaccharides; Liposomes; Lung Neoplasms; Mice; Osteosarcoma; Resveratrol; STAT3 Transcription Factor | 2023 |
Structural modification of resveratrol analogue exhibits anticancer activity against lung cancer stem cells via suppression of Akt signaling pathway.
Topics: Cell Line, Tumor; Glycogen Synthase Kinase 3 beta; Humans; Lung; Lung Neoplasms; Molecular Docking Simulation; Neoplastic Stem Cells; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; Signal Transduction | 2023 |
Investigation into perturbed nucleoside metabolism and cell cycle for elucidating the cytotoxicity effect of resveratrol on human lung adenocarcinoma epithelial cells.
Topics: A549 Cells; Adenocarcinoma of Lung; Cell Cycle; Cell Survival; Deoxyribonucleotides; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Hydroxyurea; Lung Neoplasms; Resveratrol; S Phase Cell Cycle Checkpoints | 2019 |
PRMT5 Promotes Human Lung Cancer Cell Apoptosis via Akt/Gsk3β Signaling Induced by Resveratrol.
Topics: A549 Cells; Apoptosis; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction | 2019 |
Effect of SIRT1 activators and inhibitors on CD44+/CD133+‑enriched non‑small cell lung cancer cells.
Topics: A549 Cells; AC133 Antigen; Antineoplastic Agents; Apoptosis; Benzamides; Carcinoma, Non-Small-Cell Lung; Heterocyclic Compounds, 4 or More Rings; Humans; Hyaluronan Receptors; Lung Neoplasms; Naphthols; Neoplastic Stem Cells; Resveratrol; Sirtuin 1 | 2020 |
Cyclodextrin Complexation for Enhanced Stability and Non-invasive Pulmonary Delivery of Resveratrol-Applications in Non-small Cell Lung Cancer Treatment.
Topics: Administration, Inhalation; Biological Availability; Carcinoma, Non-Small-Cell Lung; Cyclodextrins; Drug Carriers; Drug Stability; Humans; Lung; Lung Neoplasms; Resveratrol; Solubility | 2020 |
Inhalable resveratrol-cyclodextrin complex loaded biodegradable nanoparticles for enhanced efficacy against non-small cell lung cancer.
Topics: A549 Cells; Administration, Inhalation; beta-Cyclodextrins; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Stability; HEK293 Cells; Humans; Lung Neoplasms; Nanoparticles; Particle Size; Resveratrol | 2020 |
Resveratrol inhibits viability and induces apoptosis in the small‑cell lung cancer H446 cell line via the PI3K/Akt/c‑Myc pathway.
Topics: Antioxidants; Apoptosis; Apoptosis Inducing Factor; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytochromes c; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Reactive Oxygen Species; Resveratrol; Signal Transduction; Small Cell Lung Carcinoma | 2020 |
The therapeutic potential of resveratrol in a mouse model of melanoma lung metastasis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chemokine CXCL10; Female; Interferon-gamma; Lung; Lung Neoplasms; Melanoma, Experimental; Mice, Inbred C57BL; Neovascularization, Pathologic; Resveratrol; T-Lymphocytes | 2020 |
Resveratrol modulates the apoptosis and autophagic death of human lung adenocarcinoma A549 cells via a p53‑dependent pathway: Integrated bioinformatics analysis and experimental validation.
Topics: A549 Cells; Adenocarcinoma of Lung; Antioxidants; Apoptosis; Autophagy; Computational Biology; Databases, Genetic; Humans; Lung Neoplasms; Resveratrol; Signal Transduction; Tumor Suppressor Protein p53 | 2020 |
Resveratrol induces PD-L1 expression through snail-driven activation of Wnt pathway in lung cancer cells.
Topics: Antioxidants; Apoptosis; B7-H1 Antigen; beta Catenin; Biomarkers, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Resveratrol; Snail Family Transcription Factors; Tumor Cells, Cultured; Wnt Proteins | 2021 |
Differential Response of Lung Cancer Cells, with Various Driver Mutations, to Plant Polyphenol Resveratrol and Vitamin D Active Metabolite PRI-2191.
Topics: Antineoplastic Agents; Antioxidants; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dihydroxycholecalciferols; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mutation; Resveratrol; Vitamins | 2021 |
Resveratrol inhibits MUC5AC expression by regulating SPDEF in lung cancer cells.
Topics: A549 Cells; Adenocarcinoma of Lung; Cisplatin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mucin 5AC; Proto-Oncogene Proteins c-ets; Resveratrol | 2021 |
Resveratrol attenuates TNBC lung metastasis by down-regulating PD-1 expression on pulmonary T cells and converting macrophages to M1 phenotype in a murine tumor model.
Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Cytokines; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Macrophages; Mice; Neoplasm Metastasis; Programmed Cell Death 1 Receptor; Resveratrol; Th1 Cells; Triple Negative Breast Neoplasms; Tumor Escape | 2021 |
Resveratrol suppresses pulmonary tumor metastasis by inhibiting platelet-mediated angiogenic responses.
Topics: A549 Cells; Adenosine Diphosphate; Animals; Antineoplastic Agents, Phytogenic; Blood Platelets; Calcium; Cell Adhesion Molecules; Drug Screening Assays, Antitumor; Human Umbilical Vein Endothelial Cells; Humans; Lung Neoplasms; Mice, Nude; Microfilament Proteins; Neoplasm Metastasis; Neovascularization, Pathologic; Phosphoproteins; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2017 |
In vitro and in vivo evaluation of targeting tumor with folate-based amphiphilic multifunctional stabilizer for resveratrol nanosuspensions.
Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Drug Delivery Systems; Drug Stability; Folic Acid; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron; Nanoparticles; Phosphatidylethanolamines; Polyethylene Glycols; Resveratrol; Stilbenes; Suspensions; Xenograft Model Antitumor Assays | 2017 |
TriCurin, a synergistic formulation of curcumin, resveratrol, and epicatechin gallate, repolarizes tumor-associated macrophages and triggers an immune response to cause suppression of HPV+ tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catechin; Curcumin; Female; Head and Neck Neoplasms; Humans; Killer Cells, Natural; Lung Neoplasms; Macrophages; Mice; Mice, Inbred C57BL; Mice, Nude; Papillomaviridae; Papillomavirus Infections; Resveratrol; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2018 |
Endothelial growth factor receptor-targeted and reactive oxygen species-responsive lung cancer therapy by docetaxel and resveratrol encapsulated lipid-polymer hybrid nanoparticles.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Drug Compounding; Drug Liberation; Drug Synergism; Endothelial Growth Factors; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Particle Size; Polyethylene Glycols; Reactive Oxygen Species; Receptors, Vascular Endothelial Growth Factor; Resveratrol; Stearic Acids; Stilbenes; Surface Properties; Taxoids | 2018 |
Regulation of Apoptosis and Radiation Sensitization in Lung Cancer Cells via the Sirt1/NF-κB/Smac Pathway.
Topics: A549 Cells; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; DNA Damage; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Mitochondrial Proteins; NF-kappa B; Radiation Tolerance; Radiation, Ionizing; Resveratrol; RNA Interference; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Stilbenes | 2018 |
Resveratrol sensitizes lung cancer cell to TRAIL by p53 independent and suppression of Akt/NF-κB signaling.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; NF-kappa B; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2018 |
Resveratrol promotes the sensitivity of small-cell lung cancer H446 cells to cisplatin by regulating intrinsic apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; bcl-X Protein; Cell Line, Tumor; Cisplatin; Cytochromes c; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Resveratrol; Small Cell Lung Carcinoma | 2018 |
Intranasal administration of resveratrol successfully prevents lung cancer in A/J mice.
Topics: Administration, Intranasal; Animals; Anticarcinogenic Agents; Apoptosis; Butanones; Carcinogenesis; Disease Models, Animal; Humans; Lung; Lung Neoplasms; Mice; Mice, Inbred Strains; Resveratrol | 2018 |
Evaluation of resveratrol radiomodifying potential for radiotherapy treatment.
Topics: Adult; Animals; Antineoplastic Agents, Phytogenic; Cell Proliferation; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Female; Gamma Rays; Healthy Volunteers; Humans; Lung Neoplasms; Lymphocytes; Radiation-Sensitizing Agents; Resveratrol; Young Adult | 2018 |
Potential of curcumin and resveratrol as biochemical and biophysical modulators during lung cancer in rats.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Carcinogenesis; Curcumin; Cytochrome P-450 Enzyme System; Drug Synergism; Lung; Lung Neoplasms; Male; Rats, Wistar; Resveratrol | 2019 |
Resveratrol-Responsive CArG Elements from the Egr-1 Promoter for the Induction of GADD45α to Arrest the G2/M Transition.
Topics: A549 Cells; Adenocarcinoma; Cell Cycle Checkpoints; Cell Cycle Proteins; Early Growth Response Protein 1; Genes, Transgenic, Suicide; Genetic Therapy; Humans; Lung Neoplasms; Neoplasms; Nuclear Proteins; Response Elements; Resveratrol; Transcriptional Activation | 2019 |
Liquid crystalline assembly for potential combinatorial chemo-herbal drug delivery to lung cancer cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Cell Proliferation; Drug Delivery Systems; Humans; Liquid Crystals; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Pemetrexed; Resveratrol; Tumor Cells, Cultured; Urethane | 2019 |
Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.
Topics: A549 Cells; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MCF-7 Cells; Neoplasm Invasiveness; Reactive Oxygen Species; Resveratrol; RNA, Small Interfering; Snail Family Transcription Factors; Tumor Suppressor Protein p53; Up-Regulation; Wound Healing | 2019 |
Resveratrol induces premature senescence in lung cancer cells via ROS-mediated DNA damage.
Topics: Blotting, Western; Cell Line, Tumor; Cellular Senescence; DNA Damage; Flow Cytometry; Humans; Lung Neoplasms; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2013 |
In vitro and in vivo evaluation of the antitumor efficiency of resveratrol against lung cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Proliferation; Female; Humans; In Vitro Techniques; Lung Neoplasms; Male; Mice; Mice, Nude; Resveratrol; Stilbenes; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2013 |
Dual role of resveratrol in modulation of genotoxicity induced by sodium arsenite via oxidative stress and apoptosis.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Arsenites; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromosome Breakage; Comet Assay; DNA Damage; Glutathione; Humans; Lung Neoplasms; Micronuclei, Chromosome-Defective; Mutagens; Neoplastic Stem Cells; Osmolar Concentration; Oxidation-Reduction; Oxidative Stress; Resveratrol; Sodium Compounds; Stilbenes | 2013 |
Pemetrexed downregulates ERCC1 expression and enhances cytotoxicity effected by resveratrol in human nonsmall cell lung cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Endonucleases; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutamates; Guanine; Humans; Lung Neoplasms; MAP Kinase Kinase 3; MAP Kinase Kinase 6; p38 Mitogen-Activated Protein Kinases; Pemetrexed; Protein Kinase Inhibitors; Resveratrol; RNA Interference; RNA, Messenger; Signal Transduction; Stilbenes; Time Factors; Transfection | 2013 |
Inhibition of breast cancer metastasis by resveratrol-mediated inactivation of tumor-evoked regulatory B cells.
Topics: Animals; B-Lymphocytes, Regulatory; Female; Forkhead Transcription Factors; Lung Neoplasms; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Resveratrol; STAT3 Transcription Factor; Stilbenes; T-Lymphocytes, Regulatory; Transforming Growth Factor beta | 2013 |
Resveratrol enhances ionizing radiation-induced premature senescence in lung cancer cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; beta-Galactosidase; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cellular Senescence; DNA Breaks, Double-Stranded; Humans; Lung Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Radiation Tolerance; Radiation-Sensitizing Agents; Reactive Oxygen Species; Resveratrol; Ribonucleotide Reductases; Stilbenes; TOR Serine-Threonine Kinases | 2013 |
Anticancer effects of thymoquinone, caffeic acid phenethyl ester and resveratrol on A549 non-small cell lung cancer cells exposed to benzo(a)pyrene.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzo(a)pyrene; Benzoquinones; Caffeic Acids; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cytokines; Glutathione; Humans; Lung Neoplasms; Malondialdehyde; NF-kappa B; Nitric Oxide; Phenylethyl Alcohol; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tumor Cells, Cultured | 2013 |
Synergistic antitumor activity of resveratrol and miR-200c in human lung cancer.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; MAP Kinase Signaling System; Mice; Mice, Nude; MicroRNAs; Neoplasm Transplantation; Resveratrol; Ribonucleotide Reductases; Stilbenes; Transfection; Transplantation, Heterologous | 2014 |
Study to evaluate molecular mechanics behind synergistic chemo-preventive effects of curcumin and resveratrol during lung carcinogenesis.
Topics: Analysis of Variance; Animals; Benzo(a)pyrene; Blotting, Western; Carbon Radioisotopes; Carcinogenesis; Curcumin; Drug Synergism; Immunohistochemistry; Lung Neoplasms; Mice; Phosphorylation; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2014 |
Knockdown of Bcl-xL enhances growth-inhibiting and apoptosis-inducing effects of resveratrol and clofarabine in malignant mesothelioma H-2452 cells.
Topics: Adenine Nucleotides; Antimetabolites, Antineoplastic; Apoptosis; Arabinonucleosides; bcl-X Protein; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Clofarabine; G2 Phase Cell Cycle Checkpoints; Gene Knockdown Techniques; Humans; Leupeptins; Lung Neoplasms; M Phase Cell Cycle Checkpoints; Mesothelioma; Mesothelioma, Malignant; Myeloid Cell Leukemia Sequence 1 Protein; Resveratrol; RNA Interference; RNA, Messenger; RNA, Small Interfering; Stilbenes | 2014 |
Resveratrol synergistically triggers apoptotic cell death with arsenic trioxide via oxidative stress in human lung adenocarcinoma A549 cells.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Drug Synergism; Humans; Lung Neoplasms; Oxidative Stress; Oxides; Resveratrol; Stilbenes | 2015 |
P62 regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Caveolin 1; Cell Line, Tumor; Cell Proliferation; fas Receptor; Humans; Lung Neoplasms; Resveratrol; RNA-Binding Proteins; Stilbenes; Transfection | 2015 |
Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas.
Topics: 3' Untranslated Regions; Adult; Animals; Antineoplastic Agents; Binding Sites; Bone Neoplasms; Cell Line, Tumor; Cell Movement; CREB-Binding Protein; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Male; Matrix Metalloproteinase 2; Mice, SCID; MicroRNAs; Neoplasm Invasiveness; Osteosarcoma; p38 Mitogen-Activated Protein Kinases; Resveratrol; Signal Transduction; Stilbenes; Time Factors; Transcription, Genetic; Transfection; Xenograft Model Antitumor Assays; Young Adult | 2015 |
Curcumin and resveratrol in combination modulate drug-metabolizing enzymes as well as antioxidant indices during lung carcinogenesis in mice.
Topics: Animals; Antioxidants; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinogens; Catalase; Curcumin; Cytochrome P-450 Enzyme System; Cytochromes b5; Glutathione; Glutathione Reductase; Glutathione Transferase; Lipid Peroxidation; Lung; Lung Neoplasms; Male; Mice; Resveratrol; Stilbenes; Superoxide Dismutase | 2015 |
Targeting lung cancer stem-like cells with TRAIL gene armed oncolytic adenovirus.
Topics: Adenoviridae; Animals; Apoptosis; Benzoquinones; Cell Line, Tumor; Cell Survival; Chromones; Enzyme Inhibitors; Female; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Humans; Lung Neoplasms; Mice, Inbred BALB C; Microscopy, Fluorescence; Morpholines; Neoplastic Stem Cells; Oncolytic Virotherapy; Oncolytic Viruses; Resveratrol; Stilbenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Resveratrol loaded gelatin nanoparticles synergistically inhibits cell cycle progression and constitutive NF-kappaB activation, and induces apoptosis in non-small cell lung cancer cells.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cattle; Cell Cycle; Cell Line, Tumor; Drug Synergism; Gelatin; Humans; Lung Neoplasms; Mice; Nanoparticles; NF-kappa B; Resveratrol; Stilbenes | 2015 |
A novel long noncoding RNA AK001796 acts as an oncogene and is involved in cell growth inhibition by resveratrol in lung cancer.
Topics: Animals; Cell Cycle; Cell Division; Cell Line, Tumor; Down-Regulation; Genetic Vectors; Growth Inhibitors; Humans; Lung Neoplasms; Mice, Nude; Microarray Analysis; Oncogenes; Resveratrol; RNA Interference; RNA, Long Noncoding; Stilbenes; Transfection; Tumor Stem Cell Assay | 2015 |
Synergistic Induction of Erlotinib-Mediated Apoptosis by Resveratrol in Human Non-Small-Cell Lung Cancer Cells by Down-Regulating Survivin and Up-Regulating PUMA.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Line, Tumor; Down-Regulation; Drug Synergism; Erlotinib Hydrochloride; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; Ribosomal Protein S6 Kinases; Signal Transduction; Stilbenes; Survivin; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53; Up-Regulation | 2015 |
Synthesis and cytotoxic activities of E-resveratrol derivatives.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Line, Tumor; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Lung Neoplasms; Resveratrol; Stilbenes; Structure-Activity Relationship; Uterine Cervical Neoplasms | 2015 |
Resveratrol Enhances Etoposide-Induced Cytotoxicity through Down-Regulating ERK1/2 and AKT-Mediated X-ray Repair Cross-Complement Group 1 (XRCC1) Protein Expression in Human Non-Small-Cell Lung Cancer Cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; RNA Interference; Signal Transduction; Stilbenes; Time Factors; Transfection; X-ray Repair Cross Complementing Protein 1 | 2015 |
Trans-Resveratrol Induces Apoptosis through ROS-Triggered Mitochondria-Dependent Pathways in A549 Human Lung Adenocarcinoma Epithelial Cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase 3; Caspase 8; Cell Line, Tumor; Cell Survival; Epithelial Cells; Fluoresceins; Humans; Lung Neoplasms; Mitochondria; Reactive Oxygen Species; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles | 2015 |
Resveratrol enhanced anticancer effects of cisplatin on non-small cell lung cancer cell lines by inducing mitochondrial dysfunction and cell apoptosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Cisplatin; Flow Cytometry; Humans; Lung Neoplasms; Mitochondria; Resveratrol; Stilbenes | 2015 |
Resveratrol reduces IL-6 and VEGF secretion from co-cultured A549 lung cancer cells and adipose-derived mesenchymal stem cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Proliferation; Coculture Techniques; Culture Media, Conditioned; Humans; Interleukin-6; Lung Neoplasms; Mesenchymal Stem Cells; Resveratrol; Stilbenes; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2016 |
ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction underlie apoptosis induced by resveratrol and arsenic trioxide in A549 cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Drug Synergism; Endoplasmic Reticulum Stress; Humans; Lung; Lung Neoplasms; Mitochondria; Oxides; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
Resveratrol analogue 4,4'-dihydroxy-trans-stilbene potently inhibits cancer invasion and metastasis.
Topics: Animals; Apoptosis; Human Umbilical Vein Endothelial Cells; Humans; Lung Neoplasms; Male; Mice; Neoplasm Invasiveness; Neoplasms, Experimental; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays | 2016 |
[Study on the resveratrol and arsenic trioxide combination induced apoptosis and its mechanism on lung adenocarcinoma cells].
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Caspase 3; Drug Synergism; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Oxidation-Reduction; Oxides; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2016 |
The synergistic effect of resveratrol in combination with cisplatin on apoptosis via modulating autophagy in A549 cells.
Topics: A549 Cells; Adenine; Adenocarcinoma, Bronchiolo-Alveolar; Apoptosis; Autophagosomes; Autophagy; Cisplatin; Drug Synergism; Humans; Lung Neoplasms; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Neoplasm Proteins; Proto-Oncogene Proteins c-akt; Resveratrol; RNA-Binding Proteins; Stilbenes | 2016 |
Effect and Mechanism of Resveratrol on the Apoptosis of Lung Adenocarcinoma Cell Line A549.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cell Proliferation; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2015 |
Cisplatin and resveratrol induce apoptosis and autophagy following oxidative stress in malignant mesothelioma cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Caspase 3; Cisplatin; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Oxidative Stress; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2016 |
ATM/CHK/p53 Pathway Dependent Chemopreventive and Therapeutic Activity on Lung Cancer by Pterostilbene.
Topics: Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; Humans; Lung Neoplasms; Proteome; Respiratory Mucosa; Resveratrol; Rheum; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2016 |
Resveratrol inhibits lung cancer growth by suppressing M2-like polarization of tumor associated macrophages.
Topics: Animals; Antineoplastic Agents; Carcinogenesis; Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; Culture Media, Conditioned; Cytokines; Humans; Lung Neoplasms; Macrophages; Mice; Resveratrol; STAT3 Transcription Factor; Stilbenes; Th2 Cells; Tumor Escape; Xenograft Model Antitumor Assays | 2017 |
Resveratrol inhibits Hexokinases II mediated glycolysis in non-small cell lung cancer via targeting Akt signaling pathway.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Glycolysis; Hexokinase; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Resveratrol and cisplatin in a malignant mesothelioma cell model.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cisplatin; Drug Synergism; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Models, Biological; Resveratrol; Stilbenes | 2016 |
Resveratrol Inhibited Non-small Cell Lung Cancer Through Inhibiting STAT-3 Signaling.
Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Gene Transfer Techniques; Humans; Lung Neoplasms; Resveratrol; STAT3 Transcription Factor; Stilbenes | 2016 |
Resveratrol-loaded folic acid-grafted dextran stearate submicron particles exhibits enhanced antitumor efficacy in non-small cell lung cancers.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Non-Small-Cell Lung; Caspase 3; Dextrans; Drug Liberation; Folic Acid; Humans; Lung Neoplasms; Mitochondria; Particle Size; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2017 |
Anti-Tumorigenic Effects of Resveratrol in Lung Cancer Cells Through Modulation of c-FLIP.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Humans; Hydrogen Peroxide; Lung Neoplasms; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; Stilbenes | 2017 |
Mechanisms of apoptotic effects induced by resveratrol, dibenzoylmethane, and their analogues on human lung carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Chalcones; Humans; Lung Neoplasms; Resveratrol; Stilbenes | 2009 |
Oral administration of resveratrol in suppression of pulmonary metastasis of BALB/c mice challenged with CT26 colorectal adenocarcinoma cells.
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Immunologic Factors; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Recurrence, Local; Neoplasm Transplantation; Random Allocation; Resveratrol; Stilbenes; Survival Analysis; Tumor Burden | 2010 |
Resveratrol protects against Cisplatin-induced cardiotoxicity by alleviating oxidative damage.
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Cisplatin; Creatine Kinase; Free Radical Scavengers; Heart; Humans; L-Lactate Dehydrogenase; Lipid Peroxidation; Lung Neoplasms; Male; Malondialdehyde; Myocardium; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2009 |
Modulatory effects of curcumin and resveratrol on lung carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Benzopyrenes; Curcumin; Drug Therapy, Combination; Glutathione; Lipid Peroxidation; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Phytotherapy; Plant Extracts; Resveratrol; Stilbenes; Superoxide Dismutase | 2010 |
Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Survival; Down-Regulation; Gene Silencing; Heme Oxygenase-1; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Neoplasm Invasiveness; NF-kappa B; Osmolar Concentration; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes | 2010 |
Anti-tumor effects of bakuchiol, an analogue of resveratrol, on human lung adenocarcinoma A549 cell line.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; Humans; Inhibitory Concentration 50; Lung Neoplasms; Membrane Potential, Mitochondrial; Mice; Osmolar Concentration; Phenols; Reactive Oxygen Species; Resveratrol; S Phase; Stilbenes; Time Factors; Tumor Suppressor Protein p53 | 2010 |
[Resveratrol inhibits EGF-induced invasion of human lung adenocarcinoma A549 cells].
Topics: Adenocarcinoma; Anticarcinogenic Agents; Blotting, Western; Cell Line, Tumor; Epidermal Growth Factor; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Resveratrol; Signal Transduction; Stilbenes | 2010 |
Resveratrol induces mitochondria-mediated AIF and to a lesser extent caspase-9-dependent apoptosis in human lung adenocarcinoma ASTC-a-1 cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Nucleus; Cell Survival; Enzyme Activation; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Protein Transport; Resveratrol; RNA Interference; Stilbenes | 2011 |
The use of mitochondrial targeting resveratrol liposomes modified with a dequalinium polyethylene glycol-distearoylphosphatidyl ethanolamine conjugate to induce apoptosis in resistant lung cancer cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cytochromes c; Dequalinium; Female; Humans; Liposomes; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Phosphatidylethanolamines; Polyethylene Glycols; Resveratrol; Stilbenes | 2011 |
Curcumin and resveratrol synergistically stimulate p21 and regulate cox-2 by maintaining adequate zinc levels during lung carcinogenesis.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzo(a)pyrene; Blotting, Western; Body Weight; Carcinogens; Curcumin; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 2; Disease Progression; Drug Synergism; Immunoenzyme Techniques; Lung Neoplasms; Male; Mice; Organ Size; Resveratrol; Stilbenes; Zinc | 2011 |
Resveratrol alters microRNA expression profiles in A549 human non-small cell lung cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; MicroRNAs; Oligonucleotide Array Sequence Analysis; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2011 |
MicroRNA-622 functions as a tumor suppressor by targeting K-Ras and enhancing the anticarcinogenic effect of resveratrol.
Topics: Animals; Anticarcinogenic Agents; Bronchi; Cell Proliferation; Cells, Cultured; Genes, Tumor Suppressor; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; MicroRNAs; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Resveratrol; Stilbenes | 2012 |
Resveratrol induces apoptosis via a Bak-mediated intrinsic pathway in human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Inducing Factor; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Caspase 9; Cell Line, Tumor; Cell Survival; Enzyme Activation; Humans; Lung Neoplasms; Membrane Proteins; Mitochondria; Proto-Oncogene Proteins; Resveratrol; Signal Transduction; Stilbenes | 2012 |
MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Cell Line, Tumor; Cell Movement; Disease Progression; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Forkhead Transcription Factors; HEK293 Cells; Humans; Lung Neoplasms; Mice; Mice, SCID; MicroRNAs; NF-kappa B; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays | 2013 |
Curcumin and resveratrol in combination modulates benzo(a)pyrene-induced genotoxicity during lung carcinogenesis.
Topics: Animals; Antimutagenic Agents; Apoptosis; Benzo(a)pyrene; Carcinogens; Curcumin; Disease Models, Animal; Drug Therapy, Combination; Lung; Lung Neoplasms; Male; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitosis; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes | 2012 |
Resveratrol prevents endothelial cells injury in high-dose interleukin-2 therapy against melanoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Endothelial Cells; Female; Immunotherapy; Interleukin-2; Killer Cells, Lymphokine-Activated; Lung Neoplasms; Melanoma; Mice; Neoplasm Transplantation; Resveratrol; Stilbenes; T-Lymphocytes, Regulatory | 2012 |
Premature mitochondrial senescence and related ultrastructural changes during lung carcinogenesis modulation by curcumin and resveratrol.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Cellular Senescence; Curcumin; Disease Models, Animal; Drug Therapy, Combination; Lung Neoplasms; Male; Mice; Mitochondria; Pulmonary Alveoli; Resveratrol; Stilbenes | 2012 |
p38 inhibitor SB203580 sensitizes the resveratrol-induced apoptosis in human lung adenocarcinoma (A549) cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Survival; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lung Neoplasms; Membrane Potential, Mitochondrial; p38 Mitogen-Activated Protein Kinases; Pyridines; Resveratrol; Stilbenes | 2012 |
Suppressing effect of resveratrol on the migration and invasion of human metastatic lung and cervical cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Movement; Cell Survival; Female; HeLa Cells; Humans; Lung Neoplasms; Male; Matrix Metalloproteinase 9; Neoplasm Metastasis; NF-kappa B; Reactive Oxygen Species; Resveratrol; Stilbenes; Transcription Factor AP-1; Transcriptional Activation; Uterine Cervical Neoplasms | 2012 |
Resveratrol exerts differential effects in vitro and in vivo against ovarian cancer cells.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Lung Neoplasms; Ovarian Neoplasms; Rats; Rats, Inbred F344; Resveratrol; Stilbenes | 2012 |
Resveratrol inhibits TGF-β1-induced epithelial-to-mesenchymal transition and suppresses lung cancer invasion and metastasis.
Topics: Antineoplastic Agents, Phytogenic; Cadherins; Carcinoma, Non-Small-Cell Lung; Cell Adhesion; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Fibronectins; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Resveratrol; Stilbenes; Transforming Growth Factor beta1; Vimentin | 2013 |
Transient transfection of a wild-type p53 gene triggers resveratrol-induced apoptosis in cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Male; MCF-7 Cells; Resveratrol; Stilbenes; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53 | 2012 |
Synthesis and evaluation of cytotoxicity of stilbene analogues.
Topics: Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Lung Neoplasms; Phytoalexins; Plant Extracts; Resveratrol; Sesquiterpenes; Stilbenes; Structure-Activity Relationship; Terpenes; Tumor Cells, Cultured | 2003 |
Functional evaluation of novel single nucleotide polymorphisms and haplotypes in the promoter regions of CYP1B1 and CYP1A1 genes.
Topics: Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Case-Control Studies; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA Primers; Gene Expression Regulation, Enzymologic; Genotype; Haplotypes; Humans; Luciferases; Lung Neoplasms; Mutagenesis, Site-Directed; Mutation; Polycyclic Aromatic Hydrocarbons; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Resveratrol; Ribonucleotide Reductases; Stilbenes; White People | 2003 |
Analysis of resveratrol as a lung cancer chemopreventive agent in A/J mice exposed to benzo[a]pyrene.
Topics: Angiogenesis Inhibitors; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Chemoprevention; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Female; Gene Expression Regulation, Neoplastic; Lung Neoplasms; Mice; Phenols; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2004 |
Resveratrol is rapidly metabolized in athymic (nu/nu) mice and does not inhibit human melanoma xenograft tumor growth.
Topics: Animals; Anticarcinogenic Agents; Cell Division; Cell Line, Tumor; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Diet; Drug Implants; Humans; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Oxidation-Reduction; Resveratrol; Stilbenes; Transplantation, Heterologous | 2006 |
Resveratrol modulates mRNA transcripts of genes related to redox metabolism and cell proliferation in non-small-cell lung carcinoma cells.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Count; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Lung Neoplasms; Oxidation-Reduction; Phosphotransferases; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Stilbenes; Structure-Activity Relationship; Transcription, Genetic; Tumor Cells, Cultured | 2007 |
Identifying the estrogen receptor coactivator PELP1 in autophagosomes.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Autophagy; Cell Cycle; Cell Proliferation; Co-Repressor Proteins; Endosomal Sorting Complexes Required for Transport; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Lysosomes; Microtubule-Associated Proteins; Models, Biological; Phosphoproteins; Protein Transport; Receptors, Estrogen; Resveratrol; Salivary Gland Neoplasms; Stilbenes; Trans-Activators; Transcription Factors; Tumor Cells, Cultured | 2007 |
Molecular mechanisms of resveratrol action in lung cancer cells using dual protein and microarray analyses.
Topics: Anticarcinogenic Agents; Carcinoma; Cell Cycle; Cell Division; Cell Line, Tumor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2007 |
SIRT1 negatively regulates HDAC1-dependent transcriptional repression by the RBP1 family of proteins.
Topics: Animals; Benzamides; Brain; Histone Deacetylase 1; Histone Deacetylases; Homeodomain Proteins; Humans; Immunoprecipitation; Inhibitor of Growth Protein 1; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Mice; Naphthols; Nuclear Proteins; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; Resveratrol; Retinol-Binding Proteins, Cellular; Sin3 Histone Deacetylase and Corepressor Complex; Sirtuin 1; Sirtuins; Stilbenes; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2008 |
Evaluation of butylated hydroxyanisole, myo-inositol, curcumin, esculetin, resveratrol and lycopene as inhibitors of benzo[a]pyrene plus 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in A/J mice.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Butylated Hydroxyanisole; Carotenoids; Curcumin; Female; Inositol; Lung Neoplasms; Lycopene; Mice; Mice, Inbred A; Nitrosamines; Resveratrol; Stilbenes; Umbelliferones | 1999 |
Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential.
Topics: Animals; Anticarcinogenic Agents; Apigenin; Catechin; Cell Division; Curcumin; Female; Flavonoids; Growth Inhibitors; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Transplantation; Quercetin; Resveratrol; Stilbenes; Tamoxifen; Tumor Cells, Cultured | 2000 |
Structural determinants for activation and block of CFTR-mediated chloride currents by apigenin.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenocarcinoma; Anesthetics, Local; Apigenin; Biological Transport; Calcium Channel Blockers; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Lidocaine; Lung; Lung Neoplasms; ortho-Aminobenzoates; Quinidine; Resveratrol; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured | 2000 |
Lung carcinogenesis: resveratrol modulates the expression of genes involved in the metabolism of PAH in human bronchial epithelial cells.
Topics: Anticarcinogenic Agents; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Bronchi; Cell Line, Transformed; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Epithelial Cells; Epoxide Hydrolases; Gene Expression; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Lung Neoplasms; Polychlorinated Dibenzodioxins; Polycyclic Aromatic Hydrocarbons; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2001 |
Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and tumor-induced neovascularization in Lewis lung carcinoma-bearing mice.
Topics: Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Apoptosis; Body Weight; Carcinoma, Lewis Lung; CD4-CD8 Ratio; Cell Cycle; Disease Models, Animal; DNA; Female; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neovascularization, Pathologic; Organ Size; Polygonaceae; Resveratrol; Spleen; Stilbenes; Thymus Gland; Tumor Cells, Cultured | 2001 |