Page last updated: 2024-08-16

resveratrol and Amyotrophic Lateral Sclerosis

resveratrol has been researched along with Amyotrophic Lateral Sclerosis in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (17.65)29.6817
2010's12 (70.59)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Bankole, O; Bonafede, R; Mariotti, R; Muccilli, M; Parrella, E; Pizzi, M; Scambi, I; Turano, E1
Nguyen, HD1
Bonafede, R; Mariotti, R; Parrella, E; Pizzi, M; Scambi, I; Schiaffino, L1
Cho, GW; Jeong, SG; Kim, SH; Yun, YC1
Bilski, AE; Pasinetti, GM; Zhao, W1
del Valle, J; Granado-Serrano, AB; Mancuso, R; Martinez, A; Modol, L; Navarro, X; Osta, R; Pallás, M; Portero-Otin, M; Ramirez-Núñez, O1
Del Valle, J; Mancuso, R; Morell, M; Navarro, X; Osta, R; Pallás, M1
Chen, L; Le, W; Li, J; Song, L; Zhang, X1
Ficarra, S; Galtieri, A; Giardina, B; Russo, A; Tellone, E1
Barber, S; Barber, SC; Higginbottom, A; Mead, RJ; Shaw, PJ1
Childers, MK; Gifondorwa, DJ; Kim, E; Markert, CD; Milligan, CE1
Fan, D; Tang, L; Wang, J; Zhang, N; Zhang, Y1
Galán, L; García, AG; Guerrero, A; Matías-Guiu, J; Vela, A; Yáñez, M1
Choi, JR; Han, S; Kang, SJ; Soon Shin, K1
Armour, SM; Baur, JA; Delalle, I; Dobbin, MM; Fischer, A; Kim, D; Nguyen, MD; Puigserver, P; Rodgers, JT; Sananbenesi, F; Sinclair, DA; Sui, G; Tsai, LH1
Aebischer, P; Kato, AC1

Reviews

2 review(s) available for resveratrol and Amyotrophic Lateral Sclerosis

ArticleYear
ALSUntangled no. 49: resveratrol.
    Amyotrophic lateral sclerosis & frontotemporal degeneration, 2019, Volume: 20, Issue:7-8

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Clinical Trials as Topic; Gastrointestinal Microbiome; Humans; Resveratrol; Sirtuin 1

2019
Resveratrol: A Focus on Several Neurodegenerative Diseases.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Humans; Huntington Disease; Mitochondria; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Resveratrol; Stilbenes

2015

Trials

1 trial(s) available for resveratrol and Amyotrophic Lateral Sclerosis

ArticleYear
CSF from amyotrophic lateral sclerosis patients produces glutamate independent death of rat motor brain cortical neurons: protection by resveratrol but not riluzole.
    Brain research, 2011, Nov-14, Volume: 1423

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Animals; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Embryo, Mammalian; Female; Glutamic Acid; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Motor Neurons; Neuroprotective Agents; Pregnancy; Rats; Resveratrol; Riluzole; Stilbenes

2011

Other Studies

14 other study(ies) available for resveratrol and Amyotrophic Lateral Sclerosis

ArticleYear
Beneficial and Sexually Dimorphic Response to Combined HDAC Inhibitor Valproate and AMPK/SIRT1 Pathway Activator Resveratrol in the Treatment of ALS Mice.
    International journal of molecular sciences, 2022, Jan-19, Volume: 23, Issue:3

    Topics: AMP-Activated Protein Kinases; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Female; Histone Deacetylase Inhibitors; Histones; Male; Mice; Mice, Transgenic; NF-kappa B; Resveratrol; Sirtuin 1; Superoxide Dismutase; Valproic Acid

2022
Resveratrol, Endocrine Disrupting Chemicals, Neurodegenerative Diseases and Depression: Genes, Transcription Factors, microRNAs, and Sponges Involved.
    Neurochemical research, 2023, Volume: 48, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Brain-Derived Neurotrophic Factor; Cyclooxygenase 2; Depression; Endocrine Disruptors; Humans; Interleukin-6; MicroRNAs; Neurodegenerative Diseases; Parkinson Disease; Resveratrol; Transcription Factors

2023
Acetylation state of RelA modulated by epigenetic drugs prolongs survival and induces a neuroprotective effect on ALS murine model.
    Scientific reports, 2018, 08-27, Volume: 8, Issue:1

    Topics: Acetylation; Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Disease Models, Animal; Epigenesis, Genetic; Histones; Mice; Motor Neurons; Neurodegenerative Diseases; Neuroprotective Agents; Prognosis; Resveratrol; Signal Transduction; Spinal Cord; Superoxide Dismutase; Transcription Factor RelA; Treatment Outcome

2018
Reduced sirtuin 1/adenosine monophosphate-activated protein kinase in amyotrophic lateral sclerosis patient-derived mesenchymal stem cells can be restored by resveratrol.
    Journal of tissue engineering and regenerative medicine, 2019, Volume: 13, Issue:1

    Topics: AMP-Activated Protein Kinases; Amyotrophic Lateral Sclerosis; Cell Differentiation; Dendrites; Female; Humans; Male; Mesenchymal Stem Cells; Resveratrol; Sirtuin 1

2019
Sirtuins as therapeutic targets of ALS.
    Cell research, 2013, Volume: 23, Issue:9

    Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Nucleus; Cytoplasm; Enzyme Inhibitors; Humans; Mice; Mitochondria; Resveratrol; Sirtuins; Stilbenes

2013
Resveratrol improves motoneuron function and extends survival in SOD1(G93A) ALS mice.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2014, Volume: 11, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Female; Male; Mice; Mice, Transgenic; Microglia; Mitochondria; Motor Activity; Motor Neurons; Neuroprotective Agents; Resveratrol; Sirtuins; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1

2014
Lack of synergistic effect of resveratrol and sigma-1 receptor agonist (PRE-084) in SOD1G⁹³A ALS mice: overlapping effects or limited therapeutic opportunity?
    Orphanet journal of rare diseases, 2014, May-21, Volume: 9

    Topics: Adenylate Kinase; Amyotrophic Lateral Sclerosis; Animals; Drug Synergism; Mice; Mice, Transgenic; Morpholines; Neural Conduction; Phosphorylation; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Resveratrol; Rotarod Performance Test; Sigma-1 Receptor; Sirtuin 1; Stilbenes; Superoxide Dismutase

2014
Resveratrol ameliorates motor neuron degeneration and improves survival in SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
    BioMed research international, 2014, Volume: 2014

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Apoptosis; Behavior, Animal; Disease Models, Animal; Female; Lipid Peroxidation; Lumbar Vertebrae; Male; Mice; Mice, Transgenic; Microscopy, Fluorescence; Motor Neurons; Muscle, Skeletal; Neurodegenerative Diseases; Oxidative Stress; Resveratrol; Spinal Cord; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Tumor Suppressor Protein p53

2014
An in vitro screening cascade to identify neuroprotective antioxidants in ALS.
    Free radical biology & medicine, 2009, Apr-15, Volume: 46, Issue:8

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Apoptosis; Blood-Brain Barrier; Caffeic Acids; Cell Culture Techniques; Cell Line; Central Nervous System; Humans; Mice; Mice, Inbred C57BL; Motor Neurons; Mutation; Oxidative Stress; Resveratrol; Small Molecule Libraries; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Transgenes; Umbelliferones

2009
A single-dose resveratrol treatment in a mouse model of amyotrophic lateral sclerosis.
    Journal of medicinal food, 2010, Volume: 13, Issue:5

    Topics: Acetylation; Amyotrophic Lateral Sclerosis; Animals; Body Weight; Diet; Disease Models, Animal; Longevity; Mice; Mice, Mutant Strains; Mutation; Psychomotor Performance; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Tumor Suppressor Protein p53

2010
Protective effects of resveratrol through the up-regulation of SIRT1 expression in the mutant hSOD1-G93A-bearing motor neuron-like cell culture model of amyotrophic lateral sclerosis.
    Neuroscience letters, 2011, Oct-10, Volume: 503, Issue:3

    Topics: Amyotrophic Lateral Sclerosis; Annexin A5; Blotting, Western; Cell Death; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Fluorescent Antibody Technique; Humans; Mitochondria; Motor Neurons; Mutation; Neuroprotective Agents; Niacinamide; Propidium; Real-Time Polymerase Chain Reaction; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Tetrazolium Salts; Thiazoles; Up-Regulation

2011
Resveratrol upregulated heat shock proteins and extended the survival of G93A-SOD1 mice.
    Brain research, 2012, Nov-05, Volume: 1483

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Disease Models, Animal; DNA-Binding Proteins; Glial Fibrillary Acidic Protein; Heat Shock Transcription Factors; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Macrophage-1 Antigen; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Chaperones; Motor Neurons; Neoplasm Proteins; Resveratrol; Spinal Cord; Stilbenes; Superoxide Dismutase; Survival Analysis; Transcription Factors; Up-Regulation

2012
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis.
    The EMBO journal, 2007, Jul-11, Volume: 26, Issue:13

    Topics: Acetylation; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Cells, Cultured; Cyclin-Dependent Kinase 5; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation; Humans; Mice; Mice, Transgenic; Mutation; Nerve Degeneration; Rats; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Tumor Suppressor Protein p53

2007
Playng defense against Lou Gehrig's disease.
    Scientific American, 2007, Volume: 297, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Animals; Axons; Brain; Cell Death; Exercise; Humans; Male; Motor Neurons; Nerve Degeneration; Nerve Growth Factors; Resveratrol; RNA Interference; Spinal Cord; Stem Cell Transplantation; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1

2007