resolvin-d2 has been researched along with Dry-Eye-Syndromes* in 1 studies
1 other study(ies) available for resolvin-d2 and Dry-Eye-Syndromes
| Article | Year |
|---|---|
Resolvin D2 elevates cAMP to increase intracellular [Ca
Under physiologic conditions, conjunctival goblet cells (CGCs) secrete mucins into the tear film to preserve ocular surface homeostasis. Specialized proresolving mediators (SPMs), like resolvins (Rvs), regulate secretion from CGCs and actively terminate inflammation. The purpose of this study was to determine if RvD2 stimulated mucin secretion and to investigate the cellular signaling components. Goblet cells were cultured from rat conjunctiva. Secretion was measured by an enzyme-linked lectin assay, change in intracellular [Ca Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cells, Cultured; Conjunctiva; Cyclic AMP; Docosahexaenoic Acids; Dry Eye Syndromes; Fura-2; Goblet Cells; Male; Mucins; Rats; Rats, Sprague-Dawley; Tears | 2019 |