Page last updated: 2024-09-04

resiquimod and Inflammation

resiquimod has been researched along with Inflammation in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (18.52)29.6817
2010's16 (59.26)24.3611
2020's6 (22.22)2.80

Authors

AuthorsStudies
Bonnert, R; Hashimoto, K; Isobe, Y; Kurimoto, A; McInally, T; Nakamura, T; Norimura, K; Ogita, H; Takaku, H; Wada, H1
Anthony, DC; Dunstan, IK; Strekalova, T; Weglinski, CM; Yates, AG; Ying, Y1
Nishizawa, K; Seki, R1
Coimbra, ES; da Silva, AD; Dib, PRB; Fung, J; Granato, JT; Kaushik, D; Macedo, GC; Petrovsky, N; Piplani, S; Salunke, DB1
Fukunaga, K; Irie, M; Kabata, H; Kagawa, S; Masaki, K; Miyata, J; Mochimaru, T; Morita, H; Okuzumi, S1
Banete, A; Basta, S; Gee, K1
Broadwell, L; Csakai, A; Deng, F; Fang, Y; Huang, J; Jiang, S; Jones, T; Ohto, U; Sakaniwa, K; Shen, S; Shi, C; Shimizu, T; Smith, C; Soti, S; Tanji, H; Yang, Y; Yin, H1
Bergmann, CC; DiSano, KD; Stohlman, SA1
Altman, MD; Andresen, B; Baker, J; Brubaker, JD; Chen, H; Chen, Y; Childers, M; Donofrio, A; Ferguson, H; Fischer, C; Fischmann, TO; Gibeau, C; Hicks, A; Jin, S; Kattar, S; Kleinschek, MA; Leccese, E; Lesburg, C; Li, C; Lim, J; Liu, D; Maclean, JKF; Mansoor, F; Moy, LY; Mulrooney, EF; Necheva, AS; Northrup, A; Presland, J; Rakhilina, L; Smith, GF; Torres, L; Yang, R; Zhang-Hoover, J1
Fan, S; Li, Y; Liu, W; Wang, N; Yang, X; Zheng, X; Zhu, Y1
Bagby, GC; Burd, I; Holtan, SG; Newell, LF; Pereira, L; Tyner, JW; Yates, JE1
Seki, R1
Bayik, D; Klinman, DM; Tross, D1
Billich, A; Guntermann, C; Joshi, K; Kinzel, B; Lehmann, JCU; Stein, T; Te, H; Weiss, J; Wollschlegel, A1
Catherine Jin, SL; Chang, CH; Chuang, TH; Hsu, LC; Lai, CY; Liu, YL; Lu, CH; Su, YW; Yeh, DW1
Baxan, N; Branca, J; Chowdhury, R; Dubois, O; Harding, SE; Hasham, MG; Lota, A; Papanikolaou, A; Prasad, SK; Rosenthal, N; Salles-Crawley, I; Sattler, S; Zhao, L1
Aguilera, FB; Bazzoni, F; Cassatella, MA; Castellucci, M; Costa, S; Girolomoni, G; Lunardi, C; Natoli, G; Ostuni, R; Rossato, M; Tamassia, N; Zimmermann, M1
Buffa, V; Doyle-Meyers, L; Fischetti, L; King, DF; Klein, K; Shattock, RJ; Siddiqui, A; Tregoning, JS; Veazey, RS1
Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Nadeem, A; Siddiqui, N1
Baxan, N; Bellahcene, M; Branca, J; Dent, O; Duffy, T; Hameed, TS; Harding, SE; Hasham, MG; Perkins, B; Rosenthal, N; Sattler, S; Schneider, MD; Stella, SE; Stuckey, DJ1
Amakawa, R; Amuro, H; Fukuhara, S; Ito, T; Katashiba, Y; Ogata, M; Sugimoto, H; Tanijiri, T; Torii, Y; Yokoi, T1
Nicholas, SA; Sumbayev, VV1
Akamatsu, K; Hirano, T; Ichikawa, T; Ichinose, M; Kanda, M; Koarai, A; Matsunaga, K; Minakata, Y; Sugiura, H; Tanaka, R; Yanagisawa, S1
Busemann, A; Cziupka, K; Diedrich, S; Hartmann, G; Heidecke, CD; Kessler, W; Koerner, P; Maier, S; Mehmcke, H; Traeger, T1
Gibbs, BF; Pchejetski, D; Sumbayev, VV; Wyszynski, RW; Yasinska, IM1
Akira, S; Amer, A; Barchet, W; Bertin, J; Body-Malapel, M; Colonna, M; Coyle, A; Franchi, L; Grant, EP; Kanneganti, TD; Núñez, G; Ozören, N; Park, JH; Vandenabeele, P; Whitfield, J1
Fredin, MF; Gillberg, PG; Jägervall, K; Jansson, L; Karlsson, A; Karlsson, L; Melgar, S; Michaëlsson, E; Rehnström, E; Utkovic, H1

Other Studies

27 other study(ies) available for resiquimod and Inflammation

ArticleYear
Synthesis and biological evaluation of 8-oxoadenine derivatives as toll-like receptor 7 agonists introducing the antedrug concept.
    Journal of medicinal chemistry, 2010, Apr-08, Volume: 53, Issue:7

    Topics: Adenine; Animals; Carboxylic Acids; Cell Line; Drug Stability; Humans; Hypersensitivity; Immunotherapy; Inflammation; Interferons; Male; Rats; Toll-Like Receptor 7

2010
Nafamostat reduces systemic inflammation in TLR7-mediated virus-like illness.
    Journal of neuroinflammation, 2022, Jan-06, Volume: 19, Issue:1

    Topics: Animals; Benzamidines; COVID-19; COVID-19 Drug Treatment; Guanidines; Illness Behavior; Imidazoles; Inflammation; Male; Mice; Serine Endopeptidases; Serine Proteinase Inhibitors; Toll-Like Receptor 7; Virus Diseases

2022
Use of TLR9 and TLR7/8 agonists in combination with d-galactosamine in exploring models for distinct severities of systemic inflammation relative to liver injury.
    Physiological research, 2020, 12-22, Volume: 69, Issue:6

    Topics: Animals; Chemical and Drug Induced Liver Injury; Galactosamine; Imidazoles; Inflammation; Lipopolysaccharides; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Severity of Illness Index; Toll-Like Receptor 7; Toll-Like Receptor 8; Toll-Like Receptor 9

2020
Toll-like receptor-7/8 agonist kill Leishmania amazonensis by acting as pro-oxidant and pro-inflammatory agent.
    The Journal of pharmacy and pharmacology, 2021, Aug-12, Volume: 73, Issue:9

    Topics: Animals; Antiprotozoal Agents; Cytokines; Female; Humans; Imidazoles; Imiquimod; Inflammation; Leishmania; Leishmaniasis; Macrophages, Peritoneal; Mice, Inbred BALB C; Nitric Oxide; Reactive Oxygen Species; Toll-Like Receptor 7; Toll-Like Receptor 8

2021
TLR7 Agonist Suppresses Group 2 Innate Lymphoid Cell-mediated Inflammation via IL-27-Producing Interstitial Macrophages.
    American journal of respiratory cell and molecular biology, 2021, Volume: 65, Issue:3

    Topics: Animals; Asthma; Chemokine CCL17; Chemokine CCL24; Eosinophils; Imidazoles; Immunity, Innate; Inflammation; Interleukin-33; Interleukins; Lung; Lymphocytes; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Knockout; Receptors, Interleukin; Signal Transduction; Toll-Like Receptor 7

2021
Sustained IL-4 priming of macrophages enhances the inflammatory response to TLR7/8 ligand R848.
    Journal of leukocyte biology, 2022, Volume: 111, Issue:2

    Topics: Animals; Antiviral Agents; Cytokines; Imidazoles; Inflammation; Interleukin-4; Ligands; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Toll-Like Receptor 7; Toll-Like Receptor 8

2022
Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a(nta)gonists.
    Nature communications, 2021, 07-16, Volume: 12, Issue:1

    Topics: Calorimetry; HEK293 Cells; Humans; Imidazoles; Inflammation; Molecular Docking Simulation; Quinolines; Recombinant Proteins; RNA; Signal Transduction; Structure-Activity Relationship; Toll-Like Receptor 8; X-Ray Diffraction

2021
An optimized method for enumerating CNS derived memory B cells during viral-induced inflammation.
    Journal of neuroscience methods, 2017, Jun-15, Volume: 285

    Topics: Animals; Antibody-Producing Cells; B-Lymphocytes; Cell Differentiation; Cell Movement; Central Nervous System; Cyclopropanes; Cytokines; Disease Models, Animal; Flow Cytometry; Guanosine; Hepatitis, Viral, Animal; Imidazoles; In Vitro Techniques; Inflammation; Mice; Mice, Inbred C57BL; Murine hepatitis virus; Spinal Cord; Spleen; Time Factors; Toll-Like Receptor 1

2017
Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation.
    Bioorganic & medicinal chemistry letters, 2017, 06-15, Volume: 27, Issue:12

    Topics: Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; High-Throughput Screening Assays; Imidazoles; Inflammation; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Inbred Lew; Structure-Activity Relationship

2017
Multiple Immunosuppressive Effects of CpG-c41 on Intracellular TLR-Mediated Inflammation.
    Mediators of inflammation, 2017, Volume: 2017

    Topics: Aminoquinolines; Animals; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Female; Fluorescent Antibody Technique; Imidazoles; Imiquimod; Immunity, Innate; Immunosuppressive Agents; Inflammasomes; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oligodeoxyribonucleotides; RAW 264.7 Cells; Signal Transduction; Toll-Like Receptor 3; Toll-Like Receptor 7; Toll-Like Receptor 8; Toll-Like Receptor 9; Zymosan

2017
PlGF enhances TLR-dependent inflammatory responses in human mononuclear phagocytes.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2017, Volume: 78, Issue:4

    Topics: Cells, Cultured; Female; Fetal Blood; Humans; I-kappa B Kinase; Imidazoles; Immunity, Innate; Inflammation; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Membrane Proteins; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; Signal Transduction; Toll-Like Receptor 7; Toll-Like Receptor 8; Tumor Necrosis Factor-alpha

2017
Toll-Like Receptor Ligand-Induced Liver Injury in D-Galactosamine-Sensitized Mice: Differences between TLR7/8 and TLR9 Ligands, Cytokine Patterns, and Cross-Tolerance Induction by TLR2 Ligand Pretreatment.
    Journal of immunology research, 2017, Volume: 2017

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cytokines; Female; Galactosamine; Imidazoles; Immune Tolerance; Immunization; Inflammation; Lectins; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Receptor Cross-Talk; Toll-Like Receptor 2; Toll-Like Receptor 7; Toll-Like Receptor 8; Toll-Like Receptor 9

2017
Factors Influencing the Differentiation of Human Monocytic Myeloid-Derived Suppressor Cells Into Inflammatory Macrophages.
    Frontiers in immunology, 2018, Volume: 9

    Topics: Cell Differentiation; Cells, Cultured; Cytokines; Cytotoxicity, Immunologic; Gene Expression Profiling; Humans; Imidazoles; Immune Tolerance; Immunotherapy; Inflammation; Inflammation Mediators; Monocytes; Myeloid-Derived Suppressor Cells; Neoplasms; NF-kappa B; STAT4 Transcription Factor; Tumor Escape

2018
Interferon regulatory factor 5 and nuclear factor kappa-B exhibit cooperating but also divergent roles in the regulation of pro-inflammatory cytokines important for the development of TH1 and TH17 responses.
    The FEBS journal, 2018, Volume: 285, Issue:16

    Topics: Antimicrobial Cationic Peptides; Cathelicidins; Cell Line; CRISPR-Cas Systems; Cytokines; Gene Knockout Techniques; Genes, Reporter; Humans; Imidazoles; Inflammation; Interferon Regulatory Factors; NF-kappa B; Response Elements; Signal Transduction; Th1 Cells; Th17 Cells; Toll-Like Receptor 8

2018
Involvement of M1 Macrophage Polarization in Endosomal Toll-Like Receptors Activated Psoriatic Inflammation.
    Mediators of inflammation, 2018, Volume: 2018

    Topics: Animals; Cell Cycle; Cell Differentiation; Computational Biology; Cytokines; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Imidazoles; Inflammation; Macrophages; Mice; Mice, Inbred BALB C; Psoriasis; THP-1 Cells; Toll-Like Receptor 7; Toll-Like Receptors

2018
Characterization of acute TLR-7 agonist-induced hemorrhagic myocarditis in mice by multiparametric quantitative cardiac magnetic resonance imaging.
    Disease models & mechanisms, 2019, 08-16, Volume: 12, Issue:8

    Topics: Animals; Female; Hemorrhage; Humans; Imidazoles; Inflammation; Iron; Male; Mice, Inbred C57BL; Multiparametric Magnetic Resonance Imaging; Myocarditis; Thrombocytopenia; Toll-Like Receptor 7

2019
Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils.
    Nature communications, 2015, Jan-23, Volume: 6

    Topics: Adaptor Proteins, Signal Transducing; Animals; Autocrine Communication; Chromatin Assembly and Disassembly; Enhancer Elements, Genetic; Genetic Loci; Granulocyte Colony-Stimulating Factor; Histones; Humans; I-kappa B Proteins; Imidazoles; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-12 Receptor beta 1 Subunit; Interleukin-6; Ligands; Mice, Inbred C57BL; Models, Biological; Neutrophil Activation; Neutrophils; Nuclear Proteins; Peritoneum; Promoter Regions, Genetic; Protein Binding; Protein Processing, Post-Translational; RNA, Messenger; Toll-Like Receptors; Transcription Factors; Tumor Necrosis Factor-alpha

2015
Evaluation of mucosal adjuvants and immunization routes for the induction of systemic and mucosal humoral immune responses in macaques.
    Human vaccines & immunotherapeutics, 2015, Volume: 11, Issue:12

    Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Antibodies; Antibody Formation; beta-Galactosidase; Chitosan; Cytokines; Female; Hemocyanins; Imidazoles; Immunity, Mucosal; Immunization; Immunoglobulin A; Immunoglobulin G; Inflammation; Injections, Intramuscular; Lipopeptides; Macaca mulatta; Mucous Membrane; Ovalbumin; Poly I-C; Thymic Stromal Lymphopoietin

2015
TLR-7 agonist attenuates airway reactivity and inflammation through Nrf2-mediated antioxidant protection in a murine model of allergic asthma.
    The international journal of biochemistry & cell biology, 2016, Volume: 73

    Topics: Animals; Antioxidants; Asthma; Bronchoalveolar Lavage; Imidazoles; Immunoblotting; Inflammation; Lipid Peroxides; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Superoxide Dismutase; Toll-Like Receptor 7; Tyrosine

2016
Systemic autoimmunity induced by the TLR7/8 agonist Resiquimod causes myocarditis and dilated cardiomyopathy in a new mouse model of autoimmune heart disease.
    Disease models & mechanisms, 2017, 03-01, Volume: 10, Issue:3

    Topics: Adaptive Immunity; Adoptive Transfer; Animals; Autoantibodies; Autoimmunity; Cardiomyopathy, Dilated; Disease Models, Animal; Female; Genetic Variation; Heart Function Tests; Imidazoles; Immunity, Cellular; Inflammation; Lymph Nodes; Male; Mutation; Myocarditis; Myocardium; Spleen; Toll-Like Receptor 7; Toll-Like Receptor 8

2017
Imidazoquinoline acts as immune adjuvant for functional alteration of thymic stromal lymphopoietin-mediated allergic T cell response.
    Journal of immunology (Baltimore, Md. : 1950), 2008, Oct-15, Volume: 181, Issue:8

    Topics: Adjuvants, Immunologic; Cells, Cultured; Cytokines; Dendritic Cells; Dermatitis, Atopic; Gene Expression Regulation; Humans; Imidazoles; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-12; OX40 Ligand; Steroids; Th2 Cells; Thymic Stromal Lymphopoietin

2008
The involvement of hypoxia-inducible factor 1 alpha in Toll-like receptor 7/8-mediated inflammatory response.
    Cell research, 2009, Volume: 19, Issue:8

    Topics: Cell Line, Tumor; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Inflammation; Interleukin-6; Macrophages; Oxidation-Reduction; Reactive Nitrogen Species; RNA; RNA, Small Interfering; Signal Transduction; Time Factors; Toll-Like Receptor 7; Toll-Like Receptor 8; Tumor Necrosis Factor-alpha

2009
Oxidative stress augments toll-like receptor 8 mediated neutrophilic responses in healthy subjects.
    Respiratory research, 2009, Jun-15, Volume: 10

    Topics: Acetylcysteine; Chemotaxis, Leukocyte; Cytokines; Flow Cytometry; Humans; Hydrogen Peroxide; Imidazoles; Inflammation; Interleukin-8; Neutrophils; Oxidative Stress; Pancreatic Elastase; Phosphorylation; Reference Values; Signal Transduction; Toll-Like Receptor 7; Toll-Like Receptor 8; Transcription Factor RelA; Virus Diseases

2009
Stimulation of TLR7 prior to polymicrobial sepsis improves the immune control of the inflammatory response in adult mice.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2011, Volume: 60, Issue:3

    Topics: Animals; B-Lymphocytes; Cytokines; Female; Humans; Imidazoles; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; RNA, Viral; Sepsis; Spleen; Thymus Gland; Toll-Like Receptor 7

2011
Differential control of hypoxia-inducible factor 1 activity during pro-inflammatory reactions of human haematopoietic cells of myeloid lineage.
    The international journal of biochemistry & cell biology, 2012, Volume: 44, Issue:11

    Topics: Basophils; Cell Lineage; Congenital Disorders of Glycosylation; HEK293 Cells; Hematopoietic System; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Inflammation; Myeloid Cells; Nitric Oxide Synthase; Peptidoglycan; Phosphorylation; Phosphoserine; Signal Transduction; Toll-Like Receptors; TOR Serine-Threonine Kinases; Von Hippel-Lindau Tumor Suppressor Protein

2012
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3.
    Nature, 2006, Mar-09, Volume: 440, Issue:7081

    Topics: Adaptor Proteins, Signal Transducing; Aminoquinolines; Animals; Antiviral Agents; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Carrier Proteins; Caspase 1; Cells, Cultured; Cytoskeletal Proteins; Enzyme Activation; Female; Imidazoles; Imiquimod; Inflammation; Interleukin-1; Interleukin-18; Legionella pneumophila; Listeria monocytogenes; Macrophages, Peritoneal; Male; Mice; Mitogen-Activated Protein Kinases; Multiprotein Complexes; Myeloid Differentiation Factor 88; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; RNA, Bacterial; Toll-Like Receptors

2006
Intra-colonic administration of the TLR7 agonist R-848 induces an acute local and systemic inflammation in mice.
    Biochemical and biophysical research communications, 2008, Mar-07, Volume: 367, Issue:2

    Topics: Animals; Colon; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Imidazoles; Immunity, Innate; Immunologic Factors; Inflammation; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Toll-Like Receptor 7

2008