resiquimod and Disease Models, Animal

Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

Topics: Animals; Autoimmune Diseases; Disease Models, Animal; Gene Expression Regulation; Imidazoles; Membrane Glycoproteins; Mice; Retinal Pigment Epithelium; Signal Transduction; Toll-Like Receptor 7; Uveitis

Topics: Adjuvants, Immunologic; Animals; Antigens, Neoplasm; Carcinoma, Pancreatic Ductal; CD8-Positive T-Lymphocytes; Disease Models, Animal; Humans; Imidazoles; Liver Neoplasms; Mice; Pancreatic Neoplasms; Radiosurgery; Toll-Like Receptor 7; Toll-Like Receptor 8; Tumor Microenvironment

Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Communication; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Drug Resistance, Neoplasm; Humans; Imidazoles; Macrophages; Male; Membrane Glycoproteins; Mice; Myeloid-Derived Suppressor Cells; Oxaliplatin; RAW 264.7 Cells; Toll-Like Receptor 7; Toll-Like Receptor 8; Tumor Microenvironment

Topics: Adaptor Proteins, Vesicular Transport; Age Factors; Animals; Animals, Newborn; Cyclic AMP; Cytokines; Disease Models, Animal; Host-Pathogen Interactions; Imidazoles; Immunity, Innate; Lung; Macrophages, Alveolar; Mice; Myeloid Differentiation Factor 88; Orthomyxoviridae; Orthomyxoviridae Infections; Respiratory Syncytial Virus Infections; Signal Transduction

Topics: Adaptation, Physiological; Amino Acid Substitution; Angiotensin-Converting Enzyme 2; Animals; Binding Sites; Caco-2 Cells; Chlorocebus aethiops; COVID-19; Disease Models, Animal; Female; High-Throughput Nucleotide Sequencing; Humans; Imidazoles; Mice; Mice, Inbred BALB C; SARS-CoV-2; Serial Passage; Spike Glycoprotein, Coronavirus; Vero Cells; Virus Replication; Whole Genome Sequencing

Topics: Adjuvants, Immunologic; Animals; Cancer Vaccines; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Emulsions; Humans; Imidazoles; Immune Checkpoint Inhibitors; Lung Neoplasms; Lymphocyte Activation; Mice; Programmed Cell Death 1 Receptor; Toll-Like Receptor 7; Toll-Like Receptor 8; Tumor Microenvironment

Topics: Animals; Antibody-Producing Cells; B-Lymphocytes; Cell Differentiation; Cell Movement; Central Nervous System; Cyclopropanes; Cytokines; Disease Models, Animal; Flow Cytometry; Guanosine; Hepatitis, Viral, Animal; Imidazoles; In Vitro Techniques; Inflammation; Mice; Mice, Inbred C57BL; Murine hepatitis virus; Spinal Cord; Spleen; Time Factors; Toll-Like Receptor 1

Topics: Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; High-Throughput Screening Assays; Imidazoles; Inflammation; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Inbred Lew; Structure-Activity Relationship

Topics: Animals; Autoantibodies; Disease Models, Animal; Disease Progression; Histidine-tRNA Ligase; Imidazoles; Major Histocompatibility Complex; Mice; Muscle, Skeletal; Myositis; Nervous System Autoimmune Disease, Experimental; Toll-Like Receptor 7; Toll-Like Receptor 8

Topics: Adjuvants, Immunologic; Animals; Antibodies, Viral; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chickens; Coronavirus Infections; Disease Models, Animal; Imidazoles; Immunity; Immunity, Cellular; Immunity, Humoral; Immunity, Mucosal; Immunization; Immunoglobulin A; Infectious bronchitis virus; Leukocytes, Mononuclear; Poultry Diseases; Specific Pathogen-Free Organisms; Transforming Growth Factor beta; Vaccination; Vaccines, Attenuated; Vaccines, Inactivated; Viral Vaccines

Topics: Animals; Anti-Allergic Agents; Antigens; Cytokines; Disease Models, Animal; Female; Hepatitis A Virus Cellular Receptor 1; Hepatitis A Virus Cellular Receptor 2; Imidazoles; Mice, Inbred BALB C; Nasal Mucosa; Ovalbumin; Rhinitis, Allergic; Spleen

Topics: Adjuvants, Immunologic; Animals; Antigens, Protozoan; Cytokines; Disease Models, Animal; Female; Imidazoles; Leishmania tropica; Leishmaniasis; Leishmaniasis Vaccines; Lipid A; Mice, Inbred BALB C; Parasite Load; Protozoan Proteins; Random Allocation; Recombinant Proteins; Toll-Like Receptors; Vaccination; Vaccines, Inactivated

Topics: Administration, Intravenous; Animals; Antiprotozoal Agents; Bone Marrow; Disease Models, Animal; Imidazoles; Interferon-gamma; Interleukin-10; Leishmania donovani; Leishmaniasis, Visceral; Leukocytes, Mononuclear; Liposomes; Liver; Mice; Mice, Inbred BALB C; Parasite Load; Spleen; Treatment Outcome

Topics: Administration, Cutaneous; Animals; Antigens, Plant; Asthma; Desensitization, Immunologic; Disease Models, Animal; Female; Imidazoles; Immunization; Immunoglobulin E; Immunoglobulin G; Mice; Premedication; Recombinant Proteins; Th1 Cells

Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Imidazoles; Immunomodulation; Immunotherapy; Ligands; Lymphocytes; Mice; Neoplasms; Paclitaxel; Poly I-C; Toll-Like Receptors; Tumor Burden; Xenograft Model Antitumor Assays

Topics: Administration, Cutaneous; Aminoquinolines; Animals; Autoantibodies; Autoimmunity; Disease Models, Animal; Imidazoles; Imiquimod; Lupus Erythematosus, Systemic; Mice; Skin; Spleen; Toll-Like Receptor 7

Topics: Administration, Topical; Animals; Antiprotozoal Agents; B-Lymphocytes; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chemoprevention; Disease Models, Animal; Female; Granulocytes; Imidazoles; Leishmaniasis, Visceral; Liver; Mice, Inbred BALB C; Spleen

Topics: Animals; Cell Movement; Chemokine CCL21; Crohn Disease; Dendritic Cells; Disease Models, Animal; Ileitis; Imidazoles; Lymph Nodes; Membrane Glycoproteins; Mice; Mice, Inbred Strains; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes, Regulatory; Toll-Like Receptor 7

Topics: Animals; Antibodies, Antinuclear; B-Lymphocytes; Caspase 1; Cells, Cultured; Disease Models, Animal; Ficoll; Genetic Predisposition to Disease; Imidazoles; Immunization; Immunoglobulin G; Immunoglobulin M; Lupus Erythematosus, Systemic; Mice, Inbred BALB C; Mice, Knockout; Nitrophenols; Ovalbumin; Phenotype; Phenylacetates; Spleen; T-Lymphocytes; Terpenes; Time Factors

Topics: Animals; Bacterial Vaccines; Biodegradable Plastics; Burkholderia pseudomallei; Dextrans; Disease Models, Animal; Drug Carriers; Imidazoles; Melioidosis; Mice; Polymers; Vaccination; Vaccines, Subunit

Topics: Animals; Animals, Newborn; Antibodies, Viral; Chlorocebus aethiops; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Enzyme-Linked Immunospot Assay; Flagellin; Imidazoles; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Orthomyxoviridae Infections; Toll-Like Receptor 7; Toll-Like Receptor 8; Vaccines, Inactivated

Topics: Animals; Cell Differentiation; Cells, Cultured; Dendritic Cells; Disease Models, Animal; Humans; Imidazoles; Interleukin-1 Receptor-Associated Kinases; Interleukin-1beta; Interleukin-23; Lithospermum; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Myeloid Differentiation Factor 88; Naphthoquinones; Psoriasis; Skin; Toll-Like Receptor 7; Toll-Like Receptor 8

Topics: Animals; Antibodies, Monoclonal, Humanized; Antibody-Dependent Cell Cytotoxicity; Antineoplastic Agents; CD4-Positive T-Lymphocytes; Disease Models, Animal; Humans; Imidazoles; Killer Cells, Natural; Lymphocyte Activation; Lymphoma; Mice; Mice, Inbred C57BL; Rituximab; Toll-Like Receptor 7

Topics: Animals; Cytokines; Disease Models, Animal; Female; Imidazoles; Immunity, Innate; Immunotherapy; Ligands; Mannans; Melanoma, Experimental; Mice; Neoplasms; Neutrophil Infiltration; Neutrophils; Phagocytosis; Poly I-C; Respiratory Burst; Toll-Like Receptors

Topics: Adaptive Immunity; Adoptive Transfer; Animals; Autoantibodies; Autoimmunity; Cardiomyopathy, Dilated; Disease Models, Animal; Female; Genetic Variation; Heart Function Tests; Imidazoles; Immunity, Cellular; Inflammation; Lymph Nodes; Male; Mutation; Myocarditis; Myocardium; Spleen; Toll-Like Receptor 7; Toll-Like Receptor 8

Topics: Adjuvants, Immunologic; Animals; Antibodies, Helminth; Antigens, Helminth; Calpain; Disease Models, Animal; Female; Humans; Imidazoles; Immunization; Mice; Mice, Inbred C57BL; Parasite Egg Count; Schistosoma mansoni; Schistosomiasis mansoni; Treatment Outcome; Vaccines, DNA

Topics: Animals; Asthma; Disease Models, Animal; Imidazoles; Interleukin-10; Lung; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Ovalbumin; T-Lymphocytes, Regulatory; Toll-Like Receptor 7; Transforming Growth Factor beta

Topics: Administration, Inhalation; Allergens; Animals; Dendritic Cells; Disease Models, Animal; Hypersensitivity; Imidazoles; Ligands; Lipopolysaccharides; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Ovalbumin; Poly I-C; Toll-Like Receptor 3; Toll-Like Receptor 7; Toll-Like Receptor 8

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Cells; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Dendritic Cells; Diclofenac; Disease Models, Animal; Female; Glioma; Imidazoles; Immune Tolerance; Interferon-gamma; Interleukin-10; Interleukin-12; Interleukin-2 Receptor alpha Subunit; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Phosphorylation; T-Lymphocytes, Regulatory; Transcriptional Activation; Up-Regulation

Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Disease Models, Animal; Imidazoles; Lymphocyte Activation; Lymphoma; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; T-Lymphocytes, Cytotoxic; Toll-Like Receptor 7

Topics: Animals; Colon; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Imidazoles; Immunity, Innate; Immunologic Factors; Inflammation; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Toll-Like Receptor 7

Topics: Aminoquinolines; Animals; Cell Proliferation; Chronic Disease; Disease Models, Animal; Goblet Cells; Hyperplasia; Ligands; Lung; Lymphocyte Count; Male; Muscle, Smooth; Rats; Rats, Inbred BN; Th1 Cells; Th2 Cells; Toll-Like Receptor 7; Toll-Like Receptor 8