resiniferatoxin has been researched along with Sunburn* in 1 studies
1 other study(ies) available for resiniferatoxin and Sunburn
| Article | Year |
|---|---|
Disruption of the Sensory System Affects Sterile Cutaneous Inflammation In Vivo.
Increasing evidence suggests that nerve fibers responding to noxious stimuli (nociceptors) modulate immunity in a variety of tissues, including the skin. Yet, the role of nociceptors in regulating sterile cutaneous inflammation remains unexplored. To address this question, we have developed a detailed description of the sterile inflammation caused by overexposure to UVB irradiation (i.e., sunburn) in the mouse plantar skin. Using this model, we observed that chemical depletion of nociceptor terminals did not alter the early phase of the inflammatory response to UVB, but it caused a significant increase in the number of dendritic cells and αβ Topics: Animals; Calcitonin Gene-Related Peptide; Dendritic Cells; Dermatitis; Disease Models, Animal; Diterpenes; Female; Humans; Mice; Mice, Knockout; Nerve Fibers; Neurotoxins; Nociceptors; Skin; Sunburn; TRPA1 Cation Channel; TRPV Cation Channels; Ultraviolet Rays | 2019 |