resiniferatoxin has been researched along with Ear-Diseases* in 2 studies
2 other study(ies) available for resiniferatoxin and Ear-Diseases
| Article | Year |
|---|---|
Evidence for a novel protective role of the vanilloid TRPV1 receptor in a cutaneous contact allergic dermatitis model.
The purpose of this study was to examine the involvement of the transient receptor potential vanilloid receptor 1 (TRPV1) in inflammatory processes observed in murine allergic contact dermatitis (ACD). Oxazolone-induced ACD evoked a significant ear swelling after 24-72 h. It was augmented in TRPV1 knockout mice at all time points and supported by histological analysis and measure of TNF-alpha. However, tissue swelling and cytokine generation was significantly reduced in both neurokinin 1 receptor and calcitonin gene-related peptide (CGRP) knockout mice. A protective involvement of the TRPV1 receptor was identified of contact dermatitis distinct from mechanisms involving the major pro-inflammatory neuropeptides. Topics: Adjuvants, Immunologic; Animals; Calcitonin Gene-Related Peptide; Cytokines; Dermatitis, Allergic Contact; Disease Models, Animal; Diterpenes; Ear Diseases; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Oxazolone; Piperidines; Quinuclidines; Time Factors; TRPV Cation Channels | 2005 |
The effect of daphnane esters on platelet aggregation and erythema of the mouse ear.
Topics: Animals; Diterpenes; Ear Diseases; Erythema; Humans; In Vitro Techniques; Mice; Platelet Aggregation | 1980 |