reserpine has been researched along with Tremor in 55 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A new, non-invasive method for measuring reserpine-induced tremor in rodents is described here." | 7.69 | A simple, non-invasive method for the measurement of reserpine-induced tremor in rats. ( Clincke, G; Meert, TF; Naranji, F; Rombouts, J; Voeten, J, 1997) |
| "Drugs which reduce central catecholamine activity increased the tremorigenic action physostigmine (0." | 7.65 | Modification of the tremorigenic activity of physostigmine. ( Ambrani, LM; Van Woert, MH, 1972) |
| " In rats the effect of drugs on oxotremorine tremor and oxotremorine-induced increase in brain acetylcholine has been investigated." | 7.65 | Effects of drugs on tremor and increase in brain acetylcholine produced by oxotremorine in the rat. ( Cox, B; Potkonjak, D, 1970) |
| " The extract at both the doses displayed a significant reduction in postural flexion, moderate decrease in tremor, muscular rigidity and postural immobility scores but do not exhibit significant lowering of hypokinesia score in reserpine induced Parkinsonian model." | 4.12 | Antiparkinsonian activity of Tabebuia impetiginosa bark and biochemical analysis of dopamine in rat brain homogenates. ( Kadiri, SK; Karkar, VV; Pal Roy, S; Rao Konijeti, S, 2022) |
| "A new, non-invasive method for measuring reserpine-induced tremor in rodents is described here." | 3.69 | A simple, non-invasive method for the measurement of reserpine-induced tremor in rats. ( Clincke, G; Meert, TF; Naranji, F; Rombouts, J; Voeten, J, 1997) |
| " According to pharmacological screening tests, most of the compounds of this class show marked antagonistic activity against experimentally generated pathological states in mice (tremorine and reserpine antagonism) which suggest their potential use in the therapy of Parkinson's disease." | 3.67 | [Synthesis, physical-chemical properties and pharmacologically-oriented screening studies on budipine and related 4,4-diphenylpiperidines]. ( Eistetter, K; Hackmack, G; Klosa, J; Krüger, U; Menge, HG; Schaefer, H, 1984) |
| " Finally, minaprine does not antagonize either oxotremorine-induced tremors or physiostigmine-induced lethality." | 3.66 | Pharmacological evaluation of minaprine dihydrochloride, a new psychotropic drug. ( Bizière, K; Kan, JP; Muyard, JP; Roncucci, R; Souilhac, J, 1982) |
| "Amantadine-induced tremor has been investigated using mice." | 3.65 | Amantadin e tremor, a 5-hydroxytryptamine-mediated response? ( Cox, B; Tha, SJ, 1975) |
| "Drugs which reduce central catecholamine activity increased the tremorigenic action physostigmine (0." | 3.65 | Modification of the tremorigenic activity of physostigmine. ( Ambrani, LM; Van Woert, MH, 1972) |
| " In rats the effect of drugs on oxotremorine tremor and oxotremorine-induced increase in brain acetylcholine has been investigated." | 3.65 | Effects of drugs on tremor and increase in brain acetylcholine produced by oxotremorine in the rat. ( Cox, B; Potkonjak, D, 1970) |
| "Tremor was assessed visually and with accelerometers." | 1.91 | Brain Noradrenergic Innervation Supports the Development of Parkinson's Tremor: A Study in a Reserpinized Rat Model. ( Asan, E; Biella, GEM; Bolzoni, F; Cavallari, P; Ip, CW; Isaias, IU; Pezzoli, G; Pozzi, NG; Volkmann, J, 2023) |
| "Imipramine methiodide is a quaternary derivative of imipramine which does not cross the blood-brain barrier easily." | 1.27 | Comparison of imipramine-imipraminium in mice. To elucidate central or peripheral origin of effects of imipramine. ( Frances, H; Simon, P, 1985) |
| "Reserpine was administered daily by intubation for 81 days to 3 rhesus monkeys to investigate a possible relationship with depression." | 1.25 | Effects of reserpine on the social behavior of rhesus monkeys. ( Eising, RG; Harlow, HF; McKinney, WT; Moran, EC; Suomi, SJ, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (89.09) | 18.7374 |
| 1990's | 3 (5.45) | 18.2507 |
| 2000's | 1 (1.82) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (3.64) | 2.80 |
| Authors | Studies |
|---|---|
| Pal Roy, S | 1 |
| Kadiri, SK | 1 |
| Karkar, VV | 1 |
| Rao Konijeti, S | 1 |
| Pozzi, NG | 1 |
| Bolzoni, F | 1 |
| Biella, GEM | 1 |
| Pezzoli, G | 1 |
| Ip, CW | 1 |
| Volkmann, J | 1 |
| Cavallari, P | 1 |
| Asan, E | 1 |
| Isaias, IU | 1 |
| MARKHAM, CH | 1 |
| CLARK, WG | 1 |
| WINTERS, WD | 1 |
| PATTEN, BM | 1 |
| SAKAMOTO, A | 1 |
| VANWOERT, MH | 1 |
| PAPAVASILIOU, PS | 1 |
| COTZIAS, GC | 1 |
| ROOS, BE | 1 |
| STEG, G | 1 |
| THEOBALD, W | 1 |
| BUECH, O | 1 |
| KUNZ, HA | 1 |
| MORPURGO, C | 1 |
| STENGER, EG | 1 |
| WILHELMI, G | 1 |
| FUJIWARA, M | 1 |
| YAMAWAKI, T | 1 |
| SHIMAMOTO, K | 1 |
| LESSIN, AW | 1 |
| LONG, RF | 1 |
| PARKES, MW | 1 |
| Björkman, S | 1 |
| Lewander, T | 1 |
| Karlsson, JA | 1 |
| Koskinen, LO | 1 |
| Zetterström, T | 1 |
| Schaefer, H | 1 |
| Hackmack, G | 1 |
| Eistetter, K | 1 |
| Krüger, U | 1 |
| Menge, HG | 1 |
| Klosa, J | 1 |
| Brewster, D | 1 |
| Dettmar, PW | 1 |
| Metcalf, G | 1 |
| Bizière, K | 1 |
| Kan, JP | 1 |
| Souilhac, J | 1 |
| Muyard, JP | 1 |
| Roncucci, R | 1 |
| Salamone, J | 1 |
| Baskin, P | 1 |
| Nickel, B | 1 |
| Kolasiewicz, W | 1 |
| Szelenyi, I | 1 |
| Meert, TF | 1 |
| Rombouts, J | 1 |
| Voeten, J | 1 |
| Naranji, F | 1 |
| Clincke, G | 1 |
| Fukuzaki, K | 1 |
| Kamenosono, T | 1 |
| Nagata, R | 1 |
| Paulson, G | 1 |
| Cox, B | 3 |
| Tha, SJ | 1 |
| David, J | 1 |
| Kaul, CL | 1 |
| Grewal, RS | 1 |
| Poirier, LJ | 4 |
| Péchadre, JC | 1 |
| Larochelle, L | 4 |
| Dankova, J | 1 |
| Boucher, R | 2 |
| Duvoisin, RC | 1 |
| Ghosal, S | 1 |
| Sharma, PV | 1 |
| Chaudhuri, RK | 1 |
| Bhattacharya, SK | 1 |
| McDermed, JD | 1 |
| McKenzie, GM | 1 |
| Phillips, AP | 1 |
| Colpaert, FC | 1 |
| Rushkevich, IuE | 1 |
| Frances, H | 1 |
| Simon, P | 1 |
| van Beek, MC | 1 |
| Timmerman, H | 1 |
| Van Woert, MH | 2 |
| Sethy, VH | 1 |
| Ambani, LM | 1 |
| Langelier, P | 1 |
| Bédard, P | 3 |
| Parent, A | 2 |
| Roberge, AG | 1 |
| Marsden, CD | 1 |
| Sourkes, TL | 1 |
| Srimal, RC | 1 |
| Singh, HK | 1 |
| Dhawan, BN | 1 |
| Chibanguza, G | 1 |
| Brossi, A | 1 |
| Pool, W | 1 |
| Sheppard, H | 1 |
| Burns, JJ | 1 |
| Kaiser, A | 1 |
| Bigler, R | 1 |
| Bartholini, G | 1 |
| Pletscher, A | 1 |
| Cheah, JS | 1 |
| Ungerstedt, U | 1 |
| Fuxe, K | 1 |
| Goldstein, M | 1 |
| Battista, A | 1 |
| Ogawa, M | 1 |
| Anagnoste, B | 1 |
| Ambrani, LM | 1 |
| Borgman, RJ | 2 |
| Mcphillips, JJ | 2 |
| Stitzel, RE | 2 |
| Goodman, IJ | 1 |
| Sofia, RD | 1 |
| Kubena, RK | 1 |
| Barry, H | 1 |
| Horst, WD | 1 |
| Pool, WR | 1 |
| Spiegel, HE | 1 |
| Baylor, MR | 1 |
| Potkonjak, D | 2 |
| Nose, T | 1 |
| Kojima, M | 1 |
| Ishida, R | 1 |
| Shintomi, K | 1 |
| Kowa, Y | 1 |
| Balzano, E | 1 |
| Naquet, R | 1 |
| McKinney, WT | 1 |
| Eising, RG | 1 |
| Moran, EC | 1 |
| Suomi, SJ | 1 |
| Harlow, HF | 1 |
| Jurna, I | 1 |
| Grossmann, W | 1 |
| Nell, T | 1 |
| Pozos, RS | 1 |
| Holbrook, JR | 1 |
| Himwich, WA | 2 |
| Goldstein, SL | 1 |
| Fox, MW | 1 |
| Rovine, BW | 1 |
| Goldstein, S | 1 |
| Leiner, K | 1 |
| Stout, M | 1 |
| Nikki, P | 1 |
| Ostrovskaia, RU | 1 |
| Dill, RE | 1 |
| Nickey, WM | 1 |
| Little, MD | 1 |
| Faith, ME | 1 |
| Young, LD | 1 |
| Grabarits, F | 1 |
| Harvey, JA | 1 |
1 review available for reserpine and Tremor
| Article | Year |
|---|---|
Effects of chronic administration of neuroleptics: dyskinesias in monkeys.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Butyrophenones; Depression, Chemical; Drug Toleranc | 1976 |
1 trial available for reserpine and Tremor
| Article | Year |
|---|---|
A double-blind trial of reserpine in small doses as an adjunct in the treatment of hyperthyroidism.
Topics: Adult; Clinical Trials as Topic; Female; Humans; Hyperkinesis; Hyperthyroidism; Male; Middle Aged; P | 1972 |
53 other studies available for reserpine and Tremor
| Article | Year |
|---|---|
Antiparkinsonian activity of Tabebuia impetiginosa bark and biochemical analysis of dopamine in rat brain homogenates.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adjuvants, Immunologic; Animals; Antioxidants; Antipar | 2022 |
Brain Noradrenergic Innervation Supports the Development of Parkinson's Tremor: A Study in a Reserpinized Rat Model.
Topics: Animals; Brain; Humans; Male; Norepinephrine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reserpi | 2023 |
EFFECT OF ALPHA-METHYL DOPA AND RESERPINE IN HUNTINGTON'S CHOREA, PARKINSON'S DISEASE AND OTHER MOVEMENT DISORDERS.
Topics: Adolescent; Chorea; Dystonia Musculorum Deformans; Dystonic Disorders; Genetic Diseases, X-Linked; H | 1963 |
TREMORINE-INDUCED TREMOR VERSUS EXTRAPYRAMIDAL DISEASE.
Topics: Anura; Diarrhea; Exophthalmos; Extrapyramidal Tracts; Heterocyclic Compounds; Hypothalamus; Mice; Pa | 1964 |
THE EFFECT OF L-3, 4-DIHYDROXYPHENYLALANINE AND DL-5-HYDROXYTRYPTOPHAN ON RIGIDITY AND TREMOR INDUCED BY RESERPINE, CHLORPROMAZINE AND PHENOXYBENZAMINE.
Topics: 5-Hydroxytryptophan; Amino Acids; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Inulin; Movement | 1964 |
[COMPARATIVE PHARMACOLOGICAL INVESTIGATIONS WITH TOFRANIL, PERTOFRAN AND INSIDON].
Topics: Acetylcholine; Amphetamine; Amphetamines; Anesthetics; Animals; Antidepressive Agents; Catatonia; Ca | 1964 |
EFFECTS OF MONOAMINE RELEASERS ON THE TREMOR CONVULSIONS AND LETHAL EFFECTS OF NICOTINE IN MICE.
Topics: Alkaloids; Amines; Dopamine; Hypnotics and Sedatives; Methyldopa; Mice; Nicotine; Pharmacology; Rauw | 1964 |
CENTRAL STIMULANT ACTIONS OF ALPHA-ALKYL SUBSTITUTED TRYPTAMINES IN MICE.
Topics: Body Temperature; Brain; Carboxy-Lyases; Central Nervous System Stimulants; Indoles; Injections, Int | 1965 |
Thermic and tremorogenic effects of thyroliberin (TRH) in reserpine-treated mice--the non-involvement of GABA-ergic mechanisms.
Topics: Animals; Baclofen; Body Temperature Regulation; Dose-Response Relationship, Drug; Hydroxybutyrates; | 1981 |
[Synthesis, physical-chemical properties and pharmacologically-oriented screening studies on budipine and related 4,4-diphenylpiperidines].
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Drug Evaluation, Preclinical; Lethal Dose 50; Magn | 1984 |
Biologically stable analogues of TRH with increased neuropharmacological potency.
Topics: Animals; Body Temperature Regulation; Brain; Fever; Kinetics; Male; Mice; Organ Specificity; Pyrroli | 1981 |
Pharmacological evaluation of minaprine dihydrochloride, a new psychotropic drug.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Catalepsy; Dextroamphetamine; Drug Evaluation; Dru | 1982 |
Vacuous jaw movements induced by acute reserpine and low-dose apomorphine: possible model of parkinsonian tremor.
Topics: Animals; Antipsychotic Agents; Apomorphine; Dopamine Agonists; Dose-Response Relationship, Drug; Jaw | 1996 |
Quantification of rigidity and tremor activity in rats by using a new device and its validation by different classes of drugs.
Topics: Analgesics, Opioid; Animals; Antiparkinson Agents; Central Nervous System Depressants; Male; Muscari | 1997 |
A simple, non-invasive method for the measurement of reserpine-induced tremor in rats.
Topics: Animals; Electric Conductivity; Electronics; Female; Rats; Rats, Wistar; Reserpine; Sympatholytics; | 1997 |
Effects of ropinirole on various parkinsonian models in mice, rats, and cynomolgus monkeys.
Topics: Animals; Antiparkinson Agents; Bromocriptine; Catalepsy; Dopamine Agonists; Indoles; Macaca fascicul | 2000 |
Amantadin e tremor, a 5-hydroxytryptamine-mediated response?
Topics: Amantadine; Animals; Brain; Brain Chemistry; Fenclonine; Hydroxyindoleacetic Acid; Mice; Mice, Inbre | 1975 |
Pharmacological & biochemical characterization of antiparkinson drugs in reserpinized mice.
Topics: Animals; Antiparkinson Agents; Ataxia; Blepharoptosis; Catatonia; Disease Models, Animal; Humans; Ma | 1979 |
Stereotaxic lesions and movement disorders in monkeys.
Topics: Animals; Brain; Brain Mapping; Butyrophenones; Catalepsy; Catatonia; Cerebellum; Chorea; Haplorhini; | 1975 |
Parkinsonism: animal analogues of the human disorder.
Topics: Animals; Butyrophenones; Chlorpromazine; Disease Models, Animal; Haplorhini; Hydroxydopamines; Levod | 1976 |
Chemical constituents of gentianaceae XIV: tetraoxygenated and pentaoxygenated xanthones of Swertia purpurascens Wall.
Topics: Amphetamine; Animals; Chromatography, Thin Layer; Dogs; Drug Synergism; Ethers; Flavonoids; Hexobarb | 1975 |
Synthesis and pharmacology of some 2-aminotetralins. Dopamine receptor agonists.
Topics: Amines; Animals; Chloralose; Dogs; Dopamine; Electromyography; Humans; Male; Naphthalenes; Rats; Rec | 1975 |
Pharmacological characteristics of tremor, rigidity and hypokinesia induced by reserpine in rat.
Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Female; Haloperidol; Levodop | 1987 |
[Age characteristics of the development of a reserpine model of parkinsonism in rats].
Topics: Aging; Animals; Caudate Nucleus; Dyskinesia, Drug-Induced; Globus Pallidus; Male; Parkinson Disease, | 1987 |
Comparison of imipramine-imipraminium in mice. To elucidate central or peripheral origin of effects of imipramine.
Topics: Animals; Apomorphine; Body Temperature; Drug Synergism; Imipramine; Male; Mice; Motor Activity; Oxot | 1985 |
Some benzhydryl derivatives as central dopamine receptor stimulating agents.
Topics: Animals; Apomorphine; Behavior, Animal; Benzyl Compounds; Brain; Chlorpromazine; Dihydroxyphenylalan | 1974 |
Effect of phenothiazines on central cholinergic activity.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Brain; Brain Chemistry; Chlorp | 1974 |
Dopaminergic and cholinergic mechanisms in relation to postural tremor in the monkey and circling movements in the cat.
Topics: Acetylcholine; Amphetamine; Animals; Cats; Corpus Striatum; Disease Models, Animal; Dopamine; Fronta | 1974 |
Drug treatment of diseases characterized by abnormal movements.
Topics: Chorea; Diazepam; Ethanol; Haloperidol; Humans; Huntington Disease; Levodopa; Movement Disorders; My | 1973 |
Correlative neuroanatomical and neuropharmacological study of tremor and catatonia in the monkey.
Topics: Animals; Catatonia; Cerebellum; Cerebral Cortex; Dihydroxyphenylalanine; Dopamine; Haplorhini; Human | 1971 |
Experimental evidence for imipramine like activity of fenfluramine.
Topics: Animals; Avoidance Learning; Blepharoptosis; Blood Pressure; Body Temperature; Cats; Columbidae; Dru | 1970 |
[Control of motor activity in relation to monoaminergic mechanisms].
Topics: Animals; Brain; Catatonia; Cerebellum; Corpus Striatum; Dopamine; Dopamine Antagonists; Haplorhini; | 1972 |
[The emetic action of theophylline in the dog].
Topics: Animals; Chlorpromazine; Dogs; Dose-Response Relationship, Drug; Emetics; Haloperidol; Myotonia; Nau | 1974 |
L-DOPA: chemical modifications and biological evaluation.
Topics: Animals; Antiparkinson Agents; Blepharoptosis; Catatonia; Disease Models, Animal; Humans; Hypothermi | 1974 |
Action of m-tyrosine in experimental models: evidence for possible antiparkinsonian activity.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Benserazide; Brain Chemistry; Denervation; Dihydrox | 1973 |
Modification of the tremorigenic activity of physostigmine.
Topics: Animals; Behavior, Animal; Catecholamines; Chlorpromazine; Dihydroxyphenylalanine; Drug Synergism; M | 1972 |
Synthesis and pharmacology of centrally acting dopamine derivatives qnd analogs in relation to parkinson's disease.
Topics: Acetylation; Alkylation; Animals; Body Temperature; Chemical Phenomena; Chemistry; Dopamine; Hydroly | 1973 |
Inactivity of delta9-tetrahydrocannabinol in antidepressant screening tests.
Topics: Animals; Antidepressive Agents; Atropine; Behavior, Animal; Body Temperature; Cannabis; Dronabinol; | 1973 |
Correlation between brain dopamine levels and 1-dopa activity in anti-Parkinson tests.
Topics: Animals; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Blepharoptosis; Brain; | 1973 |
Alpha-methyldopamine derivatives. Synthesis and pharmacology.
Topics: Animals; Apomorphine; Blepharoptosis; Body Temperature; Depression, Chemical; Dihydroxyphenylalanine | 1974 |
An investigation of the tremorgenic actions of harmine in the rat.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Brain Chemistry; Carbamates; Guinea Pigs; In Vitro Tech | 1971 |
[Pharmacological properties of 6,6,9-trimethyl-9-azabicyclo (3,3,1)non-3 beta-yl-alpha, alpha-di(2-thienyl) glycolate hydrochloride monohydrate (PG-501), a new anti-parkinsonian agent].
Topics: Acetylcholine; Analgesics; Anesthetics, Local; Animals; Anticonvulsants; Barbiturates; Behavior, Ani | 1971 |
[Effect of reserpine on the photosensitive Papio papio: changes in behavior and electroencephalography].
Topics: Age Factors; Animals; Behavior, Animal; Body Temperature Regulation; Catatonia; Electroencephalograp | 1970 |
Effects of reserpine on the social behavior of rhesus monkeys.
Topics: Animals; Behavior, Animal; Exploratory Behavior; Female; Haplorhini; Locomotion; Macaca; Male; Postu | 1971 |
Depression by amantadine of drug-induced rigidity in the rat.
Topics: Amantadine; Animals; Depression, Chemical; Electrodes, Implanted; Electromyography; Motor Activity; | 1972 |
Tremorogenisis: effects of reserpine on the substantia nigra.
Topics: Animals; Cell Nucleus; Computers; Cytoplasmic Granules; Dogs; Electromyography; Forelimb; Hand; Huma | 1971 |
Psychoactive agents in dogs with bilateral lesions in subcortical structures.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Caudate Nucleus; Dogs; Movement Disorders; Quinoline | 1968 |
Psychoactive agents in dogs with bilateral lesions in subcortical structures.
Topics: 5-Hydroxytryptophan; Animals; Caudate Nucleus; Chlorpromazine; Dogs; Dopamine; Haloperidol; Hippocam | 1971 |
Arecoline and halothane shivering in thyroxine-treated mice.
Topics: Adjuvants, Anesthesia; Anesthesia, Inhalation; Animals; Body Temperature; Halothane; Hyperthyroidism | 1969 |
Effects of drugs on tremor and increase in brain acetylcholine produced by oxotremorine in the rat.
Topics: Acetylcholine; Animals; Brain; Brain Chemistry; Male; Phenoxybenzamine; Phenylalanine; Propranolol; | 1970 |
[The basic pharmacologic properties of several 2-substituted tryptamines].
Topics: Animals; Brain; Cerebral Cortex; Electroencephalography; Mice; Movement Disorders; Rabbits; Rats; Re | 1967 |
Dyskinesia in rats following chemical stimulation of the neostriatum.
Topics: Animals; Carbachol; Dopamine; Extrapyramidal Tracts; Male; Motor Activity; Movement Disorders; Norep | 1968 |
Differences in the duration of reserpine action in the rat depending on the measure employed.
Topics: Amines; Animals; Avoidance Learning; Blepharoptosis; Brain; Conditioning, Psychological; Depression, | 1968 |