reserpine has been researched along with Subarachnoid Hemorrhage in 15 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomized study was carried out to determine if the administration of reserpine and kanamycin to lower the concentration of vasoactive biogenic monoamines would reduce the incidence of cerebral vascular ischemic complications and death following the rupture of intracranial aneurysms." | 5.04 | Reduced incidence of cerebral ischemia following rupture of intracranial aneurysms. ( Bacon, V; Candia, G; Candia, M; Kido, D; Pessin, MS; Rosoff, CB; Zervas, NT, 1979) |
| "Patients suffering from a subarachnoid hemorrhage who were admitted to the Neurosurgical Unit of the Royal Perth Hospital during the period 1971 to 1979 were assessed with regard to the effectiveness of preoperative treatment with epsilon-aminocaproic acid, kanamycin, and reserpine." | 3.66 | Medical management of patients following a ruptured cerebral aneurysm, with epsilon-aminocaproic acid, kanamycin, and reserpine. ( Knuckey, NW; Stokes, BA, 1982) |
| "Acute subarachnoid hemorrhage is influenced by cerebral edema, acute obstructive extraventricular hydrocephalus with high or normal intracranial pressure and vascular spasms." | 1.26 | [Treatment of acute subarachnoidal hemorrhage]. ( Hartmann, A, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (93.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Slosberg, PS | 1 |
| Noseworthy, TW | 1 |
| Weir, B | 1 |
| Boisvert, D | 1 |
| Espinosa, F | 1 |
| Overton, T | 1 |
| Marshal, ML | 1 |
| Knuckey, NW | 1 |
| Stokes, BA | 1 |
| Hartmann, A | 1 |
| Sundt, TM | 1 |
| Szurszewski, J | 1 |
| Sharbrough, FW | 1 |
| Zervas, NT | 4 |
| Candia, M | 1 |
| Candia, G | 1 |
| Kido, D | 1 |
| Pessin, MS | 1 |
| Rosoff, CB | 3 |
| Bacon, V | 1 |
| Mabe, H | 1 |
| Tanabe, Y | 1 |
| Kagawa, Y | 1 |
| Takada, M | 1 |
| Yamada, H | 1 |
| Sakata, K | 1 |
| Hori, H | 1 |
| Kuwayama, A | 1 |
| Salzman, EW | 1 |
| Robertson, JT | 1 |
| Hawkins, WE | 1 |
| Clower, BR | 2 |
| McNair, JL | 1 |
| Sanford, RA | 1 |
| Allcock, JM | 1 |
3 reviews available for reserpine and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Physiological considerations important for the management of vasospasm.
Topics: Albuterol; Aminophylline; Autonomic Nervous System; Blood Pressure; Cerebrovascular Circulation; Hum | 1977 |
Vasospasm: an update.
Topics: Angiotensin II; Animals; Blood; Cerebral Angiography; Cerebral Arteries; Diagnosis, Differential; Di | 1979 |
Cerebral arterial spasm: current concepts.
Topics: Anesthesia, General; Animals; Blood Coagulation; Blood Platelets; Brain; Catecholamines; Cerebral Ar | 1974 |
1 trial available for reserpine and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Reduced incidence of cerebral ischemia following rupture of intracranial aneurysms.
Topics: Cerebral Infarction; Clinical Trials as Topic; Humans; Intracranial Aneurysm; Ischemic Attack, Trans | 1979 |
11 other studies available for reserpine and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Re: The neuroprotective effect of dexmedetomidine in the hippocampus of rabbits after subarachnoid hemorrhage (Cosar et al. Surg Neurol 2009;71:54-59).
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Dexmedetomidine; Disease Models, Animal | 2009 |
Effect of reserpine-kanamycin treatment on chronic vasospasm after platelet-enriched subarachnoid hemorrhage in primates.
Topics: Animals; Blood Platelets; Chronic Disease; Drug Therapy, Combination; Female; Ischemic Attack, Trans | 1984 |
Medical management of patients following a ruptured cerebral aneurysm, with epsilon-aminocaproic acid, kanamycin, and reserpine.
Topics: Aminocaproates; Aminocaproic Acid; Drug Therapy, Combination; Female; Humans; Intracranial Aneurysm; | 1982 |
[Treatment of acute subarachnoidal hemorrhage].
Topics: Antifibrinolytic Agents; Codeine; Guanethidine; Humans; Hydrocephalus; Hypertension; Intensive Care | 1980 |
[The role of sympathetic nerve and vasoactive amines in experimental cerebral vasospasm in dogs (author's transl)].
Topics: Animals; Basilar Artery; Dogs; Ischemic Attack, Transient; Norepinephrine; Radiography; Reserpine; S | 1978 |
[Ultrastructural changes in cerebral arterial wall and cerebral vasopasm--an experimental study (author's transl)].
Topics: Animals; Basilar Artery; Dogs; Ischemic Attack, Transient; Muscle, Smooth; Necrosis; Norepinephrine; | 1978 |
Experimental inhibition of serotonin by antibiotic: prevention of cerebral vasospasm.
Topics: Animals; Cerebral Angiography; Disease Models, Animal; Evaluation Studies as Topic; Haplorhini; Isch | 1974 |
Cerebral arterial spasm. Modification by inhibition of platelet function.
Topics: Angiotensin II; Animals; Basilar Artery; Blood Platelets; Bradykinin; Brain; Catecholamines; Cats; C | 1973 |
Myocardial damage after head trauma and simulated intracranial haemorrhage in mice: the role of the autonomic nervous system.
Topics: Adrenal Glands; Adrenalectomy; Animals; Atropine; Autonomic Nervous System; Cardiomyopathies; Catech | 1971 |
The effect of reserpine pretreatment on myocardial damage associated with simulated intracranial hemorrhage in mice.
Topics: Animals; Cardiomyopathies; Cerebral Hemorrhage; Female; Mice; Myocardium; Necrosis; Reserpine; Subar | 1970 |
Arterial spasm in subarachnoid haemorrhage. A clinical and experimental study.
Topics: Animals; Cerebral Angiography; Dogs; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Meth | 1966 |