reserpine has been researched along with Stroke in 6 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serum uric acid independently predicts cardiovascular events in older persons with isolated systolic hypertension." | 9.09 | Serum uric acid, diuretic treatment and risk of cardiovascular events in the Systolic Hypertension in the Elderly Program (SHEP). ( Applegate, WB; Di Bari, M; Franse, LV; Pahor, M; Shorr, RI; Somes, GW; Wan, JY, 2000) |
| "Serum uric acid independently predicts cardiovascular events in older persons with isolated systolic hypertension." | 5.09 | Serum uric acid, diuretic treatment and risk of cardiovascular events in the Systolic Hypertension in the Elderly Program (SHEP). ( Applegate, WB; Di Bari, M; Franse, LV; Pahor, M; Shorr, RI; Somes, GW; Wan, JY, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| LWIN, R | 1 |
| NOZAWA, G | 1 |
| HOSHINO, T | 1 |
| LEONBERG, SC | 1 |
| GREEN, JB | 1 |
| ELLIOTT, FA | 1 |
| Perry, HM | 1 |
| Davis, BR | 1 |
| Price, TR | 1 |
| Applegate, WB | 2 |
| Fields, WS | 1 |
| Guralnik, JM | 1 |
| Kuller, L | 1 |
| Pressel, S | 1 |
| Stamler, J | 1 |
| Probstfield, JL | 1 |
| Franse, LV | 1 |
| Pahor, M | 1 |
| Di Bari, M | 1 |
| Shorr, RI | 1 |
| Wan, JY | 1 |
| Somes, GW | 1 |
| Chen, H | 1 |
| Higashino, H | 1 |
| Maeda, K | 1 |
| Zhang, Z | 1 |
| Ohta, Y | 1 |
| Wang, Z | 1 |
| Su, DF | 1 |
| Yuan, WJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000514] | Phase 3 | 0 participants | Interventional | 1984-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for reserpine and Stroke
| Article | Year |
|---|---|
Effect of treating isolated systolic hypertension on the risk of developing various types and subtypes of stroke: the Systolic Hypertension in the Elderly Program (SHEP).
Topics: Aged; Antihypertensive Agents; Atenolol; Brain Ischemia; Cerebral Hemorrhage; Chlorthalidone; Double | 2000 |
Serum uric acid, diuretic treatment and risk of cardiovascular events in the Systolic Hypertension in the Elderly Program (SHEP).
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Biomarkers; Cardiovascular Dis | 2000 |
4 other studies available for reserpine and Stroke
| Article | Year |
|---|---|
Medical management of cerebrovascular accidents.
Topics: Anticoagulants; Antihypertensive Agents; Cerebrovascular Disorders; Chymotrypsin; Disease Management | 1963 |
[ON APOPLEXY IN A CERTAIN REGION AND THE PROPHYLACTIC USE OF ANTIHYPERTENSIVE AGENTS].
Topics: Adolescent; Antihypertensive Agents; Benzothiadiazines; Cerebrovascular Disorders; Child; Epidemiolo | 1964 |
THE RESPONSE OF STROKE PATIENTS TO VERY SMALL DOSES OF PARENTERAL RESERPINE.
Topics: Aged; Blood Pressure Determination; Cerebrovascular Disorders; Drug Therapy; Epilepsy; Geriatrics; H | 1964 |
Reduction of cardiac norepinephrine improves postischemic heart function in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Cardiac Output; Cardiomegaly; Coronary Circulation; Creatine Kinase; Heart Rate; Hemodynami | 2001 |