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reserpine and Scleroderma, Systemic

reserpine has been researched along with Scleroderma, Systemic in 12 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199012 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blunt, RJ1
Porter, JM2
Acevedo, A1
Palacios, JM1
López, R1
Palma, F1
Nilsen, KH1
Jayson, MI1
Rösch, J1
Meyers, D1
Knorr, M1
Schmid, A1
steurer, J1
Vetter, W1
Schütter, FW1
Sandmann, W1
Loose, DA1
Siegel, RC1
Fries, JF1
Birk, RE2
Rupe, CE1
Fuleihan, FJ1
Kurban, AK1
Abboud, RT1
Beidas-Jubran, N1
Farah, FS1
Romeo, SG1
Whalen, RE1
Tindall, JP1

Reviews

1 review available for reserpine and Scleroderma, Systemic

ArticleYear
Raynaud syndrome.
    Seminars in arthritis and rheumatism, 1981, Volume: 10, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Angiography; Antibodies, Antinuclear; Arterial Occlusive Disease

1981

Trials

1 trial available for reserpine and Scleroderma, Systemic

ArticleYear
Intra-arterially administered reserpine and saline in scleroderma.
    Archives of internal medicine, 1974, Volume: 134, Issue:3

    Topics: Adult; Clinical Trials as Topic; Female; Fingers; Humans; Injections, Intra-Arterial; Middle Aged; P

1974

Other Studies

10 other studies available for reserpine and Scleroderma, Systemic

ArticleYear
[Sympatholytic effect of intra-arterial reserpine in sclerodermia and Raynaud's disease].
    Revista medica de Chile, 1984, Volume: 112, Issue:6

    Topics: Adult; Aged; Body Temperature; Female; Hand; Humans; Middle Aged; Raynaud Disease; Regional Blood Fl

1984
Cutaneous microcirculation in systemic sclerosis and response to intra-arterial reserpine.
    British medical journal, 1980, Jun-14, Volume: 280, Issue:6229

    Topics: Cold Temperature; Hand; Humans; Injections, Intra-Arterial; Microcirculation; Raynaud Disease; Reser

1980
Hand angiography and Raynaud's syndrome.
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1977, Volume: 127, Issue:1

    Topics: Adolescent; Adult; Aged; Angiography; Arthritis; Cold Temperature; Female; Hand; Humans; Lupus Eryth

1977
Treatment of scleroderma.
    The Medical journal of Australia, 1977, Jun-11, Volume: 1, Issue:24

    Topics: 4-Aminobenzoic Acid; Aminobenzoates; Drug Therapy, Combination; Female; Humans; Middle Aged; Reserpi

1977
[Raynaud syndrome].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1986, Jul-15, Volume: 75, Issue:29

    Topics: Adolescent; Fingers; Humans; Infusions, Parenteral; Male; Raynaud Disease; Reserpine; Scleroderma, S

1986
[Diagnosis and therapy of the acral ischemia syndrome].
    Deutsche medizinische Wochenschrift (1946), 1985, Sep-20, Volume: 110, Issue:38

    Topics: Angiography; Diagnosis, Differential; Foot; Hand; Humans; Ischemia; Raynaud Disease; Recurrence; Res

1985
The treatment of systemic sclerosis with disodium edta, pyridoxine and reserpine.
    Henry Ford Hospital medical journal, 1966, Volume: 14, Issue:2

    Topics: Adult; Aged; Edetic Acid; Female; Humans; Male; Middle Aged; Pyridoxine; Reserpine; Scleroderma, Sys

1966
Treatment of systemic sclerosis.
    Modern treatment, 1966, Volume: 3, Issue:6

    Topics: Edetic Acid; Humans; Pyridoxine; Reserpine; Scleroderma, Systemic

1966
An objective evaluation of the treatment of systemic scleroderma with disodium EDTA, pyridoxine and reserpine.
    The British journal of dermatology, 1968, Volume: 80, Issue:3

    Topics: Adult; Edetic Acid; Female; Humans; Male; Pyridoxine; Reserpine; Respiratory Function Tests; Sclerod

1968
Intra-arterial administration of reserpine. Its use in patients with Raynaud's disease or Raynaud's phenomenon.
    Archives of internal medicine, 1970, Volume: 125, Issue:5

    Topics: Adult; Aged; Brachial Artery; Female; Humans; Injections, Intra-Arterial; Male; Middle Aged; Raynaud

1970