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reserpine and Ptosis, Eyelid

reserpine has been researched along with Ptosis, Eyelid in 100 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Research Excerpts

ExcerptRelevanceReference
" Subsequently, ptosis and hypothermia induced by reserpine were assessed."3.83Antidepressant-like effects of the Radix Bupleuri and Radix Paeoniae Alba drug pair. ( Gao, S; Gao, SM; Li, R; Wang, Y; Yu, CQ; Zhang, M, 2016)
" A possible mechanism was explored in the test of antagonism of reserpine-induced ptosis and hypothermia in mice."3.76Antidepressant-like effect of genipin in mice. ( Chi, W; Cui, YL; Dong, TJ; Gao, S; Hu, LM; Liu, LP; Tian, JS, 2010)
" Therefore, the aim of this study was to compare the effects of the racemic pirlindole (a selective and reversible MAO-A inhibitor) and its two enantiomers using biochemical techniques (in vitro and ex vivo determination of rat brain MAO-A and MAO-B activity) and behavioural models (forced swimming test and reserpine-induced hypothermia and palpebral ptosis test)."3.70Comparative study of pirlindole, a selective RIMA, and its two enantiomers using biochemical and behavioural techniques. ( Bruhwyler, J; Chleide, E; Damas, J; de Tullio, P; Decamp, E; Delarge, J; Dresse, A; Géczy, J; Gérardy, J; Lejeune, C; Liégeois, JF, 1998)
" Lortalamine antagonises in a dose-related manner reserpine-induced ptosis and hypothermia, and is far more potent than imipramine in this regard."3.67Pharmacology of lortalamine, a new potent non-tricyclic antidepressant. ( Berthelon, JJ; Betbeder-Matibet, A; Bonhomme, Y; Depin, JC; Muller, AJ, 1985)
" Proadifen antagonized the action of IMI when investigated in reserpine hypothermia and ptosis and in the behavioral despair test."3.66Influence of proadifen, an inhibitor of the metabolism of drugs, on the action of imipramine and desipramine in rats. ( Daniel, W; Maj, J; Rogóz, Z; Skuza, G; Sowińska, H, 1981)
"The reserpine-treated animal may be useful for the research of not only fibromyalgia syndrome but also FSS, especially for the research focusing on the hypothesis that FSS is associated with the disturbance of endogenous monoamine system."1.48Monoamine system disruption induces functional somatic syndromes associated symptomatology in mice. ( Azuma, R; Kawasaki, S; Miwa, M; Murai, S; Nagakura, Y; Ohsaka, N; Saito, H; Takahashi, S; Takebayashi, Y, 2018)
"Tramadol is a centrally acting analgesic that demonstrates opioid and monoaminergic properties."1.32Antidepressant-like effect of tramadol and its enantiomers in reserpinized mice: comparative study with desipramine, fluvoxamine, venlafaxine and opiates. ( Berrocoso, E; Gibert-Rahola, J; Micó, JA; Rojas-Corrales, MO, 2004)
"Sibutramine HCl is an inhibitor of the reuptake of monoamines with a pharmacological profile in rodents indicative of antidepressant activity."1.28The contribution of metabolites to the rapid and potent down-regulation of rat cortical beta-adrenoceptors by the putative antidepressant sibutramine hydrochloride. ( Buckett, WR; Hopcroft, RH; Luscombe, GP; Thomas, PC, 1989)
"Tianeptine is an antidepressant characterized by a 3-chlorodibenzothiazepin nucleus and an aminoheptanoic side chain."1.27Structure-activity relationships of tricyclic antidepressants, with special reference to tianeptine. ( Kamoun, A; Labrid, C; Malen, C; Mocaër, E; Moleyre, J; Poignant, JC, 1988)

Research

Studies (100)

TimeframeStudies, this research(%)All Research%
pre-199083 (83.00)18.7374
1990's8 (8.00)18.2507
2000's5 (5.00)29.6817
2010's4 (4.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagakura, Y1
Ohsaka, N1
Azuma, R1
Takahashi, S1
Takebayashi, Y1
Kawasaki, S1
Murai, S1
Miwa, M1
Saito, H1
Liu, X1
Liu, F1
Yue, R1
Li, Y1
Zhang, J1
Wang, S1
Zhang, S1
Wang, R1
Shan, L1
Zhang, W1
Wang, Y1
Gao, SM1
Li, R1
Zhang, M1
Gao, S2
Yu, CQ1
Mao, Q1
Huang, Z1
Ip, S1
Che, C1
Mao, QQ1
Ip, SP1
Tsai, SH1
Che, CT1
Tian, JS1
Cui, YL1
Hu, LM1
Chi, W1
Dong, TJ1
Liu, LP1
Finberg, JP1
Youdim, MB1
GARATTINI, S1
GIACHETTI, A1
PIERI, L1
RE, R1
FIELDEN, R3
GREEN, AL3
ACETO, MD4
HARRIS, LS1
MALONE, MH4
ROTH, RH1
Rojas-Corrales, MO1
Berrocoso, E1
Gibert-Rahola, J1
Micó, JA1
Tedeschi, DH3
Fowler, PJ2
Fujita, T1
Miller, RB1
Deniard, MJ1
Meignen, J1
DeFeudis, FV1
Balsara, JJ1
Gada, VP1
Nandal, NV1
Chandorkar, AG1
Poncelet, M3
Hakkou, F1
Simon, P4
Bourin, M1
Chermat, R3
Vaccari, A1
Biassoni, R1
Namba, MM1
Quock, RM1
Zapatero, J1
Basi, N1
Vilageliu, J1
Sanfeliu, C1
Bruseghini, L1
Maj, J2
Daniel, W1
Rogóz, Z2
Skuza, G2
Sowińska, H1
Castanier, L1
Rubat, C2
Coudert, P2
Albuisson, E1
Chopineau, J1
Couquelet, J1
Bastide, P1
Tronche, P1
Subarnas, A1
Tadano, T1
Oshima, Y1
Kisara, K2
Ohizumi, Y1
Nakagawa, T1
Ukai, K1
Kubo, S1
Abrahams, TP1
Faust, ML1
Varner, KJ1
Bruhwyler, J1
Liégeois, JF1
Gérardy, J1
Damas, J1
Chleide, E1
Lejeune, C1
Decamp, E1
de Tullio, P1
Delarge, J1
Dresse, A1
Géczy, J1
Almeida, RN1
Navarro, DS1
de Assis, TS1
de Medeiros, IA1
Thomas, G1
El Yacoubi, M1
Ledent, C1
Parmentier, M1
Bertorelli, R1
Ongini, E1
Costentin, J1
Vaugeois, JM1
Shika, K1
Nakata, C1
Ogura, M1
Tamada, T1
Fujimoto, Y1
Mooradian, A1
Dupont, PE1
Hlavec, AG1
Pearl, J1
Oono, S1
Uga, S1
David, J1
Kaul, CL1
Grewal, RS1
Fukushima, H2
Nakamura, M3
Yamamoto, H1
Asselin, AA1
Humber, LG3
Komlossy, J1
Hsu, SY1
Huang, CL1
Waters, IW1
Demerson, CA2
Santroch, G1
Sofia, RD1
Harakal, JJ1
Shoji, T1
Sakurada, S1
Doggett, NS1
Case, G1
Fuentes, JA1
Neff, NH1
Toscano, L1
Grisanti, G1
Fioriello, G1
Seghetti, E1
Bianchetti, A1
Bossoni, G1
Riva, M1
Boissier, JR1
Heal, DJ1
Frankland, AT1
Gosden, J1
Hutchins, LJ1
Prow, MR1
Luscombe, GP3
Buckett, WR3
Hopcroft, RH1
Thomas, PC2
Brochet, D1
Kato, T1
Katsuyama, M1
Karai, N1
Hirose, A1
Katsube, J1
Labrid, C1
Moleyre, J1
Poignant, JC1
Malen, C1
Mocaër, E1
Kamoun, A1
Michaluk, J1
Rawłów, A1
Baizman, ER1
Ezrin, AM1
Ferrari, RA1
Luttinger, D1
Balsamo, A1
Giorgi, I1
Lapucci, A1
Lucacchini, A1
Macchia, B1
Macchia, F1
Martini, C1
Rossi, A1
Burak, K1
Lipnicka, U1
Orszańska, H1
Rykowski, Z1
Witkiewicz, K1
Wrzesień, J1
Bogdal, M1
Krzywasiński, L1
Borkowska, B1
McCarthy, JR1
Wright, DL1
Schuster, AJ1
Abdallah, AH1
Shea, PJ1
Eyster, R1
Depin, JC1
Betbeder-Matibet, A1
Bonhomme, Y1
Muller, AJ1
Berthelon, JJ1
Schmidt, G2
Kusel, HJ2
Dal Ri, H1
Cockrill, S1
Somerville, AR1
Whittle, BA1
Menon, MK1
Dandiya, PC1
Barnett, A1
Taber, RI1
Roth, FE1
Gluckman, MI1
Baum, T1
Srimal, RC1
Singh, HK1
Dhawan, BN1
Cotillo, P1
Bonaccorsi, A1
Philipp, AH1
Kraml, MJ1
Charest, MP1
Tom, H1
Vávra, I1
Boshek, RL1
Boston, JE1
Brossi, A1
Pool, W1
Sheppard, H2
Burns, JJ1
Kaiser, A1
Bigler, R1
Bartholini, G1
Pletscher, A1
Fanelli, O1
Mazzoncini, V1
Trallori, L1
Ueki, S1
Ogawa, N1
Watanabe, S1
Gomita, Y1
Araki, Y1
Trepanier, DL1
Sunder, S1
Monkovic, I1
Perron, YG1
Martel, R1
Simpson, WJ1
Horst, WD1
Pool, WR2
Spiegel, HE1
Daum, SJ2
Clarke, RL2
Matier, WL1
Owens, DA1
Comer, WT1
Deitchman, D1
Ferguson, HC1
Seidehamel, RJ1
Young, JR1
Taha, AM1
Omar, NM1
Bayomi, SM1
Ammar, EM1
Afifi, A1
Borgman, RJ1
Baylor, MR1
McPhillips, JJ1
Stitzel, RE1
Felix, AM1
Winter, DP1
Wang, SS1
Kulesha, ID1
Hane, DL1
Gambino, AJ1
Kaiser, C1
Pavloff, AM1
Garvey, E1
Zirkle, CL1
Nodiff, EA1
Saggiomo, AJ1
Reed, FD1
Brown, RG1
Delgado, JN1
Isaacson, EI1
Lapin, IP1
Osipova, SV1
Uskova, NV1
Stabrovski, EM1
Stoll, RG2
Bates, TR2
Nieforth, KA3
Swarbrick, J1
Lotti, VJ1
Porter, CC1
Rohte, O1
Dhawan, KN1
Jaju, BP1
Gupta, GP1
Leszkovszky, GP1
Tardos, L1
Lendvai, J1
Takács, K1
Veldkamp, W1
Johnson, GA1
Keasling, HH1
Gibaldi, M1
Feldman, S1
Bernardi, L1
Coda, S1
Pegrassi, L1
Suchowsky, GK1
Faith, ME1
Young, LD1
Grabarits, F1
Harvey, JA1
Nematollahi, J3
Nulu, JR2
Weinstock, M1
Marshall, AS1
Decato, L1
Burger, A1
Siuda, JF1
Hochman, HI1
Guess, W1
Autian, J1
Huebner, CF1
Donoghue, EM1
Plummer, AJ1
Furness, PA1

Other Studies

100 other studies available for reserpine and Ptosis, Eyelid

ArticleYear
Monoamine system disruption induces functional somatic syndromes associated symptomatology in mice.
    Physiology & behavior, 2018, 10-01, Volume: 194

    Topics: Animals; Biogenic Monoamines; Blepharoptosis; Body Temperature; Body Weight; Central Nervous System;

2018
The antidepressant-like effect of bacopaside I: possible involvement of the oxidative stress system and the noradrenergic system.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 110

    Topics: Administration, Oral; Animals; Antidepressive Agents; Blepharoptosis; Catalase; Dose-Response Relati

2013
Antidepressant-like effects of the Radix Bupleuri and Radix Paeoniae Alba drug pair.
    Neuroscience letters, 2016, 10-28, Volume: 633

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Blepharoptosis; Brain; Bupleu

2016
Antidepressant-like effect of ethanol extract from Paeonia lactiflora in mice.
    Phytotherapy research : PTR, 2008, Volume: 22, Issue:11

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Blepharoptosis; Clomipramine; Depression; Dise

2008
Antidepressant-like effect of peony glycosides in mice.
    Journal of ethnopharmacology, 2008, Sep-26, Volume: 119, Issue:2

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Blepharoptosis; Cerebrum; Depression; Disease Mode

2008
Antidepressant-like effect of genipin in mice.
    Neuroscience letters, 2010, Aug-02, Volume: 479, Issue:3

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Blepharoptosis; Depression; D

2010
Pharmacological properties of the anti-Parkinson drug rasagiline; modification of endogenous brain amines, reserpine reversal, serotonergic and dopaminergic behaviours.
    Neuropharmacology, 2002, Volume: 43, Issue:7

    Topics: Animals; Antiparkinson Agents; Biogenic Amines; Blepharoptosis; Brain; Dopamine; Dose-Response Relat

2002
Antagonists of reserpine induced eyelid ptosis.
    Medicina experimentalis : International journal of experimental medicine, 1960, Volume: 3

    Topics: Blepharoptosis; Eyelid Diseases; Humans; Reserpine

1960
VALIDITY OF PTOSIS AS A MEASURE OF THE CENTRAL DEPRESSANT ACTION OF RESERPINE.
    The Journal of pharmacy and pharmacology, 1965, Volume: 17

    Topics: Blepharoptosis; Brain Chemistry; Bretylium Compounds; Central Nervous System; Eyelids; Mice; Myocard

1965
EFFECT OF VARIOUS AGENTS ON RESERPINE-INDUCED BLEPHAROPTOSIS.
    Toxicology and applied pharmacology, 1965, Volume: 7

    Topics: Anti-Allergic Agents; Atropine; Blepharoptosis; Chlorpromazine; Eyelids; Histamine H1 Antagonists; I

1965
Yohimbine potentiation of reserpine blepharoptosis.
    Journal of pharmaceutical sciences, 1962, Volume: 51

    Topics: Blepharoptosis; Eyelids; Reserpine; Yoga; Yohimbine

1962
Antidepressant-like effect of tramadol and its enantiomers in reserpinized mice: comparative study with desipramine, fluvoxamine, venlafaxine and opiates.
    Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:3

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Cyclohexanols;

2004
Mechanisms underlying reserpine-induced ptosis and blepharospasm: evidence that reserpine decreases central sympathetic outflow in rats.
    Life sciences, 1967, Mar-01, Volume: 6, Issue:5

    Topics: Animals; Blepharoptosis; Central Nervous System; Facial Nerve; Male; Norepinephrine; Rats; Reserpine

1967
A comparative study of the noradrenaline-depleting and sympathetic-blocking actions of guanethidine and (-)-beta-hydroxyphenethylguanidine.
    British journal of pharmacology and chemotherapy, 1967, Volume: 30, Issue:1

    Topics: Amphetamine; Animals; Blepharoptosis; Blood Pressure; Cats; Drug Antagonism; Electric Stimulation; G

1967
Reversal of reserpine-induced ptosis in the mouse by alpha-adrenoceptor-agonists.
    Psychopharmacology, 1983, Volume: 80, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Blepharoptosis; Dose-Response Relationship, Drug; Male; Muridae;

1983
Psychopharmacological investigation of the monoamine oxidase inhibitory activity of molindone, a dihydroindolone neuroleptic.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:9

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Behavior, Animal; Blepharoptosis; Catalepsy; Fenclonine;

1984
Psychopharmacological profile of diphenylhydantoin in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 1984, Volume: 8, Issue:3

    Topics: Animals; Apomorphine; Barbital; Behavior, Animal; Blepharoptosis; Drug Interactions; Male; Mice; Mot

1984
The value of the reserpine test in psychopharmacology.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:8

    Topics: Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Drug Evaluation, Preclinical; Male

1983
Gonadal influences on the inhibition of monoamine oxidase type B activity.
    Journal of neuroscience research, 1982, Volume: 8, Issue:1

    Topics: Animals; Blepharoptosis; Body Temperature; Estradiol; Female; Hypothalamus; Male; Monoamine Oxidase;

1982
Effects of narcotic antagonists on L-dopa reversal of reserpine-induced catalepsy and blepharoptosis in mice.
    Life sciences, 1981, Apr-06, Volume: 28, Issue:14

    Topics: Animals; Blepharoptosis; Catalepsy; Drug Antagonism; Drug Synergism; Humans; Kinetics; Levodopa; Mal

1981
Toxicological studies of plafibride. Part 4: Interaction of plafibride with other drugs.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a

    Topics: Animals; Blepharoptosis; Blood Pressure; Body Temperature; Clofibrate; Clofibric Acid; Dogs; Drug In

1981
Influence of proadifen, an inhibitor of the metabolism of drugs, on the action of imipramine and desipramine in rats.
    Polish journal of pharmacology and pharmacy, 1981, Volume: 33, Issue:6

    Topics: Animals; Blepharoptosis; Desipramine; Hypothermia; Imipramine; Male; Motor Activity; Proadifen; Rats

1981
Synthesis of new serotonergic 2-substituted 4,6-diaryl pyridazin-3-ones.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:9

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Blepharoptosis; Chemical Phenomena; Chemistry, Physi

1995
Behavioural profile of two potential antidepressant pyridazine derivatives including arylpiperazinyl moieties in their structure, in mice.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:2

    Topics: 5-Hydroxytryptophan; Analgesia; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Bleph

1995
Pharmacological properties of beta-amyrin palmitate, a novel centrally acting compound, isolated from Lobelia inflata leaves.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:6

    Topics: Animals; Antidepressive Agents; Apomorphine; Blepharoptosis; Catalepsy; Central Nervous System; Dose

1993
Antidepressive effects of the stereoisomer cis-dosulepin hydrochloride.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:1

    Topics: Acetylcholine; Animals; Antidepressive Agents; Apomorphine; Blepharoptosis; Body Temperature; Brain

1993
The depletion of monoamines blocks the sympathoinhibitory response to cocaine.
    Journal of the autonomic nervous system, 1996, May-06, Volume: 58, Issue:3

    Topics: Adjuvants, Anesthesia; Adrenergic Fibers; alpha-Methyltyrosine; Animals; Biogenic Monoamines; Blepha

1996
Comparative study of pirlindole, a selective RIMA, and its two enantiomers using biochemical and behavioural techniques.
    Behavioural pharmacology, 1998, Volume: 9, Issue:8

    Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Carbazoles; Female; Hypothermia; Mice; Monoam

1998
Antidepressant effect of an ethanolic extract of the leaves of Cissampelos sympodialis in rats and mice.
    Journal of ethnopharmacology, 1998, Volume: 63, Issue:3

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Blepharoptosis;

1998
Adenosine A2A receptor antagonists are potential antidepressants: evidence based on pharmacology and A2A receptor knockout mice.
    British journal of pharmacology, 2001, Volume: 134, Issue:1

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Blepharoptosis; Disease Models, Animal; Dopamine A

2001
[Inhibitory effects of methyl o-(4-hydroxy-3-methoxycinnamoyl) reserpate (CD-3400) on the central nervous system (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1977, Volume: 73, Issue:7

    Topics: Agonistic Behavior; Animals; Avoidance Learning; Blepharoptosis; Body Temperature; Cats; Central Ner

1977
3-Aminotetrahydrocarbazoles as a new series of central nervous system agents.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:4

    Topics: Amphetamine; Animals; Apomorphine; Blepharoptosis; Carbazoles; Central Nervous System; Haplorhini; H

1977
[Two cases of bilateral Horner's syndrome induced by long-term use of the adrenergic neuron blocking agents (author's transl)].
    Nippon Ganka Gakkai zasshi, 1979, Jun-10, Volume: 83, Issue:6

    Topics: Aged; Blepharoptosis; Female; Horner Syndrome; Humans; Methyldopa; Prenylamine; Reserpine

1979
Pharmacological & biochemical characterization of antiparkinson drugs in reserpinized mice.
    Indian journal of experimental biology, 1979, Volume: 17, Issue:8

    Topics: Animals; Antiparkinson Agents; Ataxia; Blepharoptosis; Catatonia; Disease Models, Animal; Humans; Ma

1979
Pharmacology of 9-gamma-methylaminopropyl-9,10-dihydro-9,10-methanoanthracene-HCl (ID-9206-HCl), a new potent antidepressant.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 229, Issue:1

    Topics: Acetylcholine; Animals; Anthracenes; Antidepressive Agents, Tricyclic; Blepharoptosis; Body Temperat

1977
Cycloalkanoindoles. 2. 1-Alkyl-1,2,3,4-tetrahydrocarbazole-1-ethanamines and related compounds. Potential antidepressants.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:6

    Topics: Animals; Antidepressive Agents, Tricyclic; Blepharoptosis; Carbazoles; Ethylamines; Indoles; Lethal

1976
The effect of tricyclic antidepressants and neuroleptics on the peripheral and central action of norepinephrine in reserpine-treated mice.
    European journal of pharmacology, 1976, Volume: 38, Issue:2

    Topics: Animals; Antidepressive Agents, Tricyclic; Blepharoptosis; Drug Synergism; Male; Mice; Mice, Inbred

1976
Effect of acylation with eleostearic acids on the monoamine oxidase inhibitory potency of some hydrazine antidepressants in mice.
    Journal of medicinal chemistry, 1975, Volume: 18, Issue:1

    Topics: Acylation; Animals; Antidepressive Agents; Behavior, Animal; Blepharoptosis; Brain; Brain Chemistry;

1975
3,4-Dihydro-1H-1,4-oxazino[4,3-a]indoles as potential antidepressants.
    Journal of medicinal chemistry, 1975, Volume: 18, Issue:6

    Topics: Animals; Antidepressive Agents; Blepharoptosis; Indoles; Lethal Dose 50; Mice; Oxazines; Reserpine

1975
Evaluation of ketamine HCl for anti-depressant activity.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 214, Issue:1

    Topics: Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Drug Synergism; Imipramine; Ketami

1975
[Effect of beta-phenylethylamine derivatives on the central nervous system. III. Motor activity changes in mice due to the intracerebral administration of metaraminol].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1975, Volume: 71, Issue:1

    Topics: Animals; Blepharoptosis; Brain; Catalepsy; Dopamine; Humans; Hydroxydopamines; Injections, Intravent

1975
Some observations on the interaction between cardiac glycosides and reserpine in the heart and central nervous system.
    Toxicology and applied pharmacology, 1975, Volume: 33, Issue:1

    Topics: Animals; Blepharoptosis; Body Temperature; Brain; Cardiac Glycosides; Catalepsy; Depression, Chemica

1975
Selective monoamine oxidase inhibitor drugs as aids in evaluating the role of type A and B enzymes.
    Neuropharmacology, 1975, Volume: 14, Issue:11

    Topics: Animals; Blepharoptosis; Body Temperature; Clorgyline; Cyclopropanes; Harmaline; In Vitro Techniques

1975
Basic derivatives of 6,7-dihydroindolo(1,7-ab)(1) benzazepine and 6H-indolo(7,1-cd)(1,5) benzoxazepine as potential antidepressant agents.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:2

    Topics: Animals; Antidepressive Agents; Benzazepines; Blepharoptosis; Body Temperature; Depression, Chemical

1976
Interaction of atropine or methylatropinium with four effects of two cholinergic drugs.
    Experientia, 1976, Mar-15, Volume: 32, Issue:3

    Topics: Animals; Atropine; Atropine Derivatives; Blepharoptosis; Drug Interactions; Ganglionic Stimulants; M

1976
A comparison of the effects of sibutramine hydrochloride, bupropion and methamphetamine on dopaminergic function: evidence that dopamine is not a pharmacological target for sibutramine.
    Psychopharmacology, 1992, Volume: 107, Issue:2-3

    Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain Chemistry; Bupropion; Chromatography, High Pre

1992
The contribution of metabolites to the rapid and potent down-regulation of rat cortical beta-adrenoceptors by the putative antidepressant sibutramine hydrochloride.
    Neuropharmacology, 1989, Volume: 28, Issue:2

    Topics: Animals; Antidepressive Agents; Blepharoptosis; Cerebral Cortex; Cyclobutanes; Dopamine; Hypothermia

1989
The pharmacology of sibutramine hydrochloride (BTS 54 524), a new antidepressant which induces rapid noradrenergic down-regulation.
    Progress in neuro-psychopharmacology & biological psychiatry, 1988, Volume: 12, Issue:5

    Topics: Adenylyl Cyclases; Animals; Antidepressive Agents, Tricyclic; Blepharoptosis; Body Temperature Regul

1988
Antidepressant-like effects of diphenylhydantoin in mice: involvement of alpha-adrenoceptors.
    European journal of pharmacology, 1986, Jan-14, Volume: 120, Issue:1

    Topics: Animals; Antidepressive Agents; Blepharoptosis; Helplessness, Learned; In Vitro Techniques; Male; Mi

1986
Reversal of the reserpine-induced ptosis by L-threo-3,4-dihydroxy-phenylserine (L-threo-DOPS), a (-)-norepinephrine precursor, and its potentiation by imipramine or nialamide.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:3

    Topics: Animals; Blepharoptosis; Brain Chemistry; Droxidopa; Drug Synergism; Imipramine; Injections, Intrave

1986
Structure-activity relationships of tricyclic antidepressants, with special reference to tianeptine.
    Clinical neuropharmacology, 1988, Volume: 11 Suppl 2

    Topics: Animals; Antidepressive Agents, Tricyclic; Blepharoptosis; Male; Mice; Mice, Inbred Strains; Reserpi

1988
Central action of the antidepressant drug pirlindole.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Carbazoles; C

1986
Pharmacologic profile of fezolamine fumarate: a nontricyclic antidepressant in animal models.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1

    Topics: Animals; Antidepressive Agents; Biological Transport; Blepharoptosis; Brain; Depression; Disease Mod

1987
3-[(2-ethoxyphenoxy)methyl]piperidine derivatives. Synthesis and antidepressant activity.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:1

    Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Desipramine; Dopamine; Drug Evaluation, Precl

1987
Synthesis of new arylanalogs of ketamine.
    Il Farmaco; edizione scientifica, 1985, Volume: 40, Issue:4

    Topics: Amphetamine; Analgesics; Animals; Anticonvulsants; Behavior, Animal; Blepharoptosis; Body Temperatur

1985
New bicyclic antidepressant agent. Synthesis and activity of napactadine and related compounds.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:11

    Topics: Aggression; Amidines; Animals; Blepharoptosis; Cerebral Cortex; Chemical Phenomena; Chemistry; Depre

1985
Pharmacology of lortalamine, a new potent non-tricyclic antidepressant.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:11

    Topics: Amphetamine; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Benzopyrans; Biogenic Amin

1985
[On the central and peripheral component with respect to the genesis of reserpine ptosis].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 257, Issue:1

    Topics: Animals; Blepharoptosis; Cats; Central Nervous System; Cocaine; Eyelids; Muscle, Smooth; Neuromuscul

1967
The action of antidepressants on the uptake of 5-HT by platelets; a comparison with other tests for antidepressant activity.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 259, Issue:2

    Topics: Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Blepharoptosis; Blood Platelets; Imipram

1968
[Effect of reserpine on sympathetic-motor innervation of the eye].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 261, Issue:1

    Topics: Action Potentials; Animals; Blepharoptosis; Cats; Cocaine; Eyelids; Motor Neurons; Neuromuscular Jun

1968
A comparison of aralkylamines and aralkylguanidines as antagonists of adrenergic neurone blockade.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:11

    Topics: Amines; Amphetamine; Animals; Blepharoptosis; Cats; Chlorpromazine; Choline; Drug Antagonism; Electr

1966
The mechanism of the tranquillizing action of asarone from Acorus calamus Linn.
    The Journal of pharmacy and pharmacology, 1967, Volume: 19, Issue:3

    Topics: Animals; Behavior, Animal; Blepharoptosis; Body Temperature; Brain Chemistry; Conditioning, Classica

1967
Activity of antihistamines in laboratory antidepressant tests.
    International journal of neuropharmacology, 1969, Volume: 8, Issue:1

    Topics: Amitriptyline; Animals; Anxiety; Blepharoptosis; Cyproheptadine; Drug Synergism; Histamine H1 Antago

1969
The pharmacology of iprindole, a new antidepressant.
    Psychopharmacologia, 1969, Volume: 15, Issue:3

    Topics: Acetylcholine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Appetite; Atropine; Bleph

1969
Experimental evidence for imipramine like activity of fenfluramine.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 188, Issue:2

    Topics: Animals; Avoidance Learning; Blepharoptosis; Blood Pressure; Body Temperature; Cats; Columbidae; Dru

1970
Observations on the interactions between desipramine and reserpine on adrenergic transmission in the rat.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:2

    Topics: Animals; Blepharoptosis; Desipramine; Electric Stimulation; Eyelids; Rats; Reserpine; Sympathetic Ne

1972
Pyrrolo(4,3,2-de)isoquinolines with central nervous system and antihypertensive activities.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:11

    Topics: Animals; Antihypertensive Agents; Blepharoptosis; Blood Pressure; Brain; Central Nervous System; Dos

1974
Proceedings: Ptosis as a model of depression.
    Psychopharmacology bulletin, 1974, Volume: 10, Issue:4

    Topics: Animals; Antidepressive Agents; Blepharoptosis; Depression; Disease Models, Animal; Humans; Imiprami

1974
L-DOPA: chemical modifications and biological evaluation.
    Advances in neurology, 1974, Volume: 5

    Topics: Animals; Antiparkinson Agents; Blepharoptosis; Catatonia; Disease Models, Animal; Humans; Hypothermi

1974
Antagonism of psychostimulant 2-phenyl-5,5-dimethyl-tetrahydro-1,4-oxazine hydrochloride (G 130) to central nervous system depressing drugs. Monoamine oxidase inhibitory activity and norepinephrine and serotonin induced changes. Comparison with dL-ampheta
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:12

    Topics: Amphetamine; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Brain Stem; Chlorprom

1974
[Psychopharmacological effects of doxepin hydrochloride].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:6

    Topics: Amitriptyline; Amphetamine; Animals; Behavior, Animal; Blepharoptosis; Body Temperature; Brain Chemi

1972
3,4-Dihydroisocarbostyril and 1,2,3,4-tetrahydroisoquinoline derivatives of ephedrine.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:4

    Topics: Amphetamine; Animals; Behavior, Animal; Blepharoptosis; Central Nervous System; Drug Synergism; Ephe

1973
Substituted tetrahydrofurfurylamines as potential antidepressants.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:4

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Blepharoptosis; Central Nervous System; Desipramin

1973
Correlation between brain dopamine levels and 1-dopa activity in anti-Parkinson tests.
    European journal of pharmacology, 1973, Volume: 21, Issue:3

    Topics: Animals; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Blepharoptosis; Brain;

1973
Compounds affecting the central nervous system. 3. 3 -Phenyltropan-2-ols.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:6

    Topics: Acylation; Animals; Behavior, Animal; Blepharoptosis; Central Nervous System; Cocaine; Mice; Rats; R

1973
Antihypertensive agents. Synthesis and biological properties of 2-amino-4-aryl-2-imidazolines.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:8

    Topics: Amines; Animals; Antihypertensive Agents; Blepharoptosis; Blood Pressure; Dogs; Guinea Pigs; Imidazo

1973
Synthesis and screening of cyclic benzylhydrazine congeners as antidepressants.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:3

    Topics: Amphetamine; Animals; Antidepressive Agents; Benzyl Compounds; Blepharoptosis; Chemical Phenomena; C

1974
Alpha-methyldopamine derivatives. Synthesis and pharmacology.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:4

    Topics: Animals; Apomorphine; Blepharoptosis; Body Temperature; Depression, Chemical; Dihydroxyphenylalanine

1974
Synthesis and antireserpine activity of peptides of L-dopa.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:4

    Topics: Animals; Antiparkinson Agents; Behavior, Animal; Blepharoptosis; Catatonia; Dihydroxyphenylalanine;

1974
Compounds affecting the central nervous system. 2. Aromatic acetals of tropanediols.
    Journal of medicinal chemistry, 1972, Volume: 15, Issue:5

    Topics: Acetals; Animals; Behavior, Animal; Blepharoptosis; Central Nervous System; Chromatography, Thin Lay

1972
Analogs of phenothiazines. 4. Effect of structure upon neuropharmacological activity of some chlorpromazine analogs of the diphenylmethane type.
    Journal of medicinal chemistry, 1972, Volume: 15, Issue:6

    Topics: Aggression; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Benzyl Compounds; Blepharopt

1972
Synthesis of 2-diphenylmethylene-1-acyl-1-alkyl hydrazines as potential psychotropic agents.
    Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:10

    Topics: Acylation; Alkylation; Animals; Antidepressive Agents; Benzene Derivatives; Blepharoptosis; Body Tem

1972
Pharmacological effects of imipramine and desmethylimipramine in developing rats.
    Psychopharmacologia, 1969, Volume: 14, Issue:4

    Topics: Age Factors; Animals; Animals, Newborn; Blepharoptosis; Brain Chemistry; Chlorpromazine; Desipramine

1969
Some physical factors affecting the enhanced blepharoptotic activity of orally administered reserpine-cholanic acid coprecipitates.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:12

    Topics: Animals; Bile Acids and Salts; Blepharoptosis; Drug Synergism; Hydrogen-Ion Concentration; Mice; Res

1969
Potentiation and inhbition of some central actions of L(-)-dopa by decarboxylase inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 172, Issue:2

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Blepharoptosis; Brain; Brai

1970
Observation of the grooming behaviour of reserpinized white mice as a method for investigating reserpine antagonism and synergism.
    Psychopharmacologia, 1970, Volume: 18, Issue:2

    Topics: Administration, Oral; Animals; Antidepressive Agents; Blepharoptosis; Charcoal; Desipramine; Dextroa

1970
Validity of antagonism of different effects of reserpine as test for anti-depressant activity.
    Psychopharmacologia, 1970, Aug-19, Volume: 18, Issue:1

    Topics: Animals; Antidepressive Agents; Avoidance Learning; Blepharoptosis; Conditioning, Psychological; Dru

1970
[Pharmacology of diphenylalkyl-derivatives. IV. Pharmacology of a noradrenaline increasing effect of dephenylpropylamine-amine-derivatives].
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:12

    Topics: Adrenalectomy; Amphetamine; Anesthetics, Local; Animals; Blepharoptosis; Blood Pressure; Cardiovascu

1967
Studies on the effects of reserpine in mice as influenced by its diluent.
    Journal of pharmaceutical sciences, 1968, Volume: 57, Issue:4

    Topics: Amines; Animals; Appetite Depressants; Benzphetamine; Blepharoptosis; Brain; Citrates; Dextroampheta

1968
Correlation of pharmacologic activity and dissolution rates of reserpine-desoxycholic acid dispersions.
    Journal of pharmaceutical sciences, 1968, Volume: 57, Issue:4

    Topics: Animals; Bile Acids and Salts; Blepharoptosis; Chemical Phenomena; Chemistry, Physical; Mice; Pharma

1968
Pharmacological properties of some derivatives of 1,3-benzoxazine.
    Experientia, 1968, Aug-15, Volume: 24, Issue:8

    Topics: Acacia; Animals; Blepharoptosis; Body Temperature; Diarrhea; Gastrointestinal Motility; Mice; Oxazin

1968
Differences in the duration of reserpine action in the rat depending on the measure employed.
    International journal of neuropharmacology, 1968, Volume: 7, Issue:6

    Topics: Amines; Animals; Avoidance Learning; Blepharoptosis; Brain; Conditioning, Psychological; Depression,

1968
Imidazolecarboxyhydrazides. II. Chemistry and biological evaluation.
    Journal of medicinal chemistry, 1969, Volume: 12, Issue:1

    Topics: Animals; Blepharoptosis; Body Temperature; Depression, Chemical; Dicarboxylic Acids; Drug Synergism;

1969
The influence of the sympathetic nervous system on the action of drugs on the lens.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 166, Issue:1

    Topics: Animals; Blepharoptosis; Body Temperature; Cataract; Chlorpromazine; Female; Guanethidine; Imipramin

1969
Bile acid enhancement of reserpine-induced blepharoptosis.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:2

    Topics: Animals; Bile Acids and Salts; Blepharoptosis; Mice; Reserpine; Solubility

1969
o,o'-Disubstituted phenylcyclopropylamines.
    Journal of medicinal chemistry, 1969, Volume: 12, Issue:2

    Topics: Amphetamine; Animals; Blepharoptosis; Hexobarbital; Imipramine; Mice; Motor Activity; Propylamines;

1969
Imidazolecarbohydrazides. 3. Chemistry and biological evaluation.
    Journal of medicinal chemistry, 1969, Volume: 12, Issue:5

    Topics: Animals; Blepharoptosis; Body Temperature Regulation; Chemical Phenomena; Chemistry; Hydrazines; Hyp

1969
Desoxycholic acid enhancement of orally administered reserpine.
    Journal of pharmaceutical sciences, 1966, Volume: 55, Issue:9

    Topics: Absorption; Animals; Bile Acids and Salts; Blepharoptosis; Drug Synergism; Mice; Reserpine

1966
Imidazolecarboxhydrazides. I. Chemistry and biological evaluation.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:5

    Topics: Animals; Blepharoptosis; Blood Pressure; Chemistry, Organic; Drug Synergism; Electrocardiography; El

1966
N-methyl-n-2-propynyl-l-indanamine. A protent monoamine oxidase inhibitor.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:6

    Topics: Animals; Behavior, Animal; Blepharoptosis; Chemistry, Organic; Drug Antagonism; Indenes; Mice; Monoa

1966