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reserpine and Pheochromocytoma, Extra-Adrenal

reserpine has been researched along with Pheochromocytoma, Extra-Adrenal in 46 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Research Excerpts

ExcerptRelevanceReference
" In the VMAT-expressing NE tumour cell lines GOT1 and BON and in VMAT-expressing primary NE tumour cell cultures (carcinoids, n=4 and pheochromocytomas, n=4), reserpine significantly reduced the uptake of (123)I-MIBG."3.72Uptake of meta-iodobenzylguanidine in neuroendocrine tumours is mediated by vesicular monoamine transporters. ( Ahlman, H; Bernhardt, P; Forssell-Aronsson, E; Johanson, V; Kölby, L; Levin-Jakobsen, AM; Nilsson, O; Wängberg, B, 2003)
"Chronic administration of reserpine is associated with the development of pheochromocytomas in rats."3.69Sustained stimulation of rat adrenal chromaffin cell proliferation by reserpine. ( Downing, JC; McClain, RM; Tischler, AS; Ziar, J, 1995)
"Adrenomedullin (AM) is a vasorelaxant peptide that was recently isolated from human pheochromocytoma."3.69Vasopressor activities of N-terminal fragments of adrenomedullin in anesthetized rat. ( Inui, T; Itahara, Y; Nakajima, K; Sakakibara, S; Watanabe, TX; Yoshizawa-Kumagaye, K, 1996)
"To elucidate how the neuropeptide Y (NPY) gene is regulated by physiological/pharmacological changes in neural functions, the expression and regulation of the NPY gene were studied by measuring changes in the abundances of NPY and NPY mRNA in the adrenal gland and brain regions of rats in vivo and in PC12 rat pheochromocytoma cells after reserpine treatment."3.68Long lasting increase in neuropeptide Y gene expression in rat adrenal gland with reserpine treatment: positive regulation of transsynaptic activation and membrane depolarization. ( Higuchi, H; Iwasa, A; Miki, N; Yoshida, H, 1990)
"Mouse pheochromocytomas are a new tool for studying genes and signaling pathways that regulate cell growth and differentiation in adrenal medullary neoplasms and are a unique model for studying the regulation of PNMT expression."1.31Pheochromocytoma cell lines from heterozygous neurofibromatosis knockout mice. ( Alroy, J; Bedri, S; Evinger, MJ; Powers, JF; Shahsavari, M; Tischler, AS; Tsokas, P, 2000)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199037 (80.43)18.7374
1990's5 (10.87)18.2507
2000's4 (8.70)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schonn, JS1
Desnos, C1
Henry, JP2
Darchen, F1
JIRANKOVA, J1
STJAERNE, L1
EULER, US1
LISHAJKO, F1
ENGELMAN, K1
SJOERDSMA, A1
PEARCE, A1
Kölby, L2
Bernhardt, P2
Levin-Jakobsen, AM1
Johanson, V1
Wängberg, B1
Ahlman, H2
Forssell-Aronsson, E2
Nilsson, O2
Jakobsen, AM1
Neilson, GH1
Tominaga, S1
Mallet, J1
Faucon Biguet, N1
Buda, M1
Lamouroux, A1
Samolyk, D1
Roisin, MP1
Isambert, MF1
Guillot, M1
Lenoir, G1
Wilson, SP1
Chang, KJ1
Viveros, OH1
Tischler, AS3
Ziar, J2
Downing, JC1
McClain, RM2
Watanabe, TX1
Itahara, Y1
Inui, T1
Yoshizawa-Kumagaye, K1
Nakajima, K1
Sakakibara, S1
Powers, JF2
Shahsavari, M2
Tsokas, P2
Downing, J1
Evinger, MJ1
Bedri, S1
Alroy, J1
Hengstmann, JH1
Dengler, HJ1
Romankiewicz, JA1
Becker, CE1
Benowitz, NL1
Greene, LA2
Rein, G2
Rahn, KH1
van den Broek, PJ1
de Graeff, J1
Haas, Th1
Denkl, P1
Higuchi, H1
Iwasa, A1
Yoshida, H1
Miki, N1
McMahon, A1
Geertman, R1
Sabban, EL1
Kittner, B2
Bräutigam, M2
Herken, H2
Shen, RS1
Zhang, YX1
Perez-Polo, JR1
Laschinski, G1
Wagner, JA1
Perret, C1
Girardet, P1
Munro, AB1
Woods, JW1
Philipp, T1
Nast, HP1
Pichlmaier, H1
Werning, C2
Siegenthaler, W2
Koch-Weser, J1
Fernandes, M1
Kim, KE1
Moyer, JH1
Tucker, RM1
Hunt, JC1
Torikai, T1
Winkelmann, W1
Heinrich, F1
Schultis, K1
Leon, AS1
Abrams, WB1
Vorburger, C1
Shimbo, S1
Fox, LP1
Grandi, J1
Johnson, AH1
Watrous, WG1
Johnson, MJ1

Reviews

9 reviews available for reserpine and Pheochromocytoma, Extra-Adrenal

ArticleYear
Opioid peptide synthesis in bovine and human adrenal chromaffin cells.
    Peptides, 1981, Volume: 2 Suppl 1

    Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Animals; Catecholamines; Cattle; Chromaffin System; Endorp

1981
[Influence of antihypertensive agents on catecholamine and metabolite excretion and its significance for the diagnosis of pheochromocytoma].
    Deutsche medizinische Wochenschrift (1946), 1975, Nov-07, Volume: 100, Issue:45

    Topics: Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Antihypertensive Agents; Catecholamines; Cloni

1975
Pharmacology and clinical use of drugs in hypertensive emergencies.
    American journal of hospital pharmacy, 1977, Volume: 34, Issue:2

    Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Aorta; Brain Diseases; Cerebral Hemorrhage; Diazox

1977
[Treatment of the hypertensive crisis].
    Schweizerische medizinische Wochenschrift, 1973, Nov-24, Volume: 103, Issue:47

    Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Antihypertensive Agents; Blood Pressure; Diaz

1973
Present day management of hypertension.
    Southern medical journal, 1974, Volume: 67, Issue:7

    Topics: Acute Kidney Injury; Angiography; Antihypertensive Agents; Aortic Aneurysm; Diet, Sodium-Restricted;

1974
Hypertensive emergencies.
    The New England journal of medicine, 1974, Jan-24, Volume: 290, Issue:4

    Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Coronary D

1974
Hypertensive emergencies.
    Pennsylvania medicine, 1974, Volume: 77, Issue:7

    Topics: Acute Kidney Injury; Adrenal Gland Neoplasms; Antihypertensive Agents; Aortic Aneurysm; Blood Volume

1974
Recent advances in the medical and surgical treatment of hypertension.
    The Medical clinics of North America, 1968, Volume: 52, Issue:5

    Topics: Adrenocortical Hyperfunction; Antihypertensive Agents; Diet, Sodium-Restricted; Diuretics; Ethacryni

1968
[Aspect of hormones and hypertension].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1969, Jul-10, Volume: 58, Issue:7

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Catechol

1969

Other Studies

37 other studies available for reserpine and Pheochromocytoma, Extra-Adrenal

ArticleYear
Transmitter uptake and release in PC12 cells overexpressing plasma membrane monoamine transporters.
    Journal of neurochemistry, 2003, Volume: 84, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Animals; Biological Transport; Carrier Proteins; Cell Membrane; Dopami

2003
[COMMENTS ON THE INTERPRETATION OF RESULTS OF THE REGITINE TEST IN THE DIAGNOSIS OF PHEOCHROMOCYTOMA].
    Sbornik lekarsky, 1963, Volume: 65

    Topics: Diagnosis; Humans; Hypertension; Hypnotics and Sedatives; Phentolamine; Pheochromocytoma; Reserpine

1963
CATECHOLAMINES AND NUCLEOTIDES IN PHAEOCHROMOCYTOMA.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Adenine Nucleotides; Adenosine Triphosphatases; Adenosine Triphosphate; Catecholamines; Chromatograp

1964
CHRONIC MEDICAL THERAPY FOR PHEOCHROMOCYTOMA; A REPORT OF FOUR CASES.
    Annals of internal medicine, 1964, Volume: 61

    Topics: Blood Pressure; Blood Pressure Determination; Carboxy-Lyases; Child; Drug Therapy; Epinephrine; Geri

1964
PITFALLS IN THE DIAGNOSIS OF PSYCHIATRIC DISEASE.
    The Practitioner, 1965, Volume: 194

    Topics: Anxiety; Anxiety Disorders; Brain Neoplasms; Carcinoid Tumor; Depression; Diagnosis; Drug Therapy; G

1965
Uptake of meta-iodobenzylguanidine in neuroendocrine tumours is mediated by vesicular monoamine transporters.
    British journal of cancer, 2003, Oct-06, Volume: 89, Issue:7

    Topics: 3-Iodobenzylguanidine; Adrenal Gland Neoplasms; Adrenergic Uptake Inhibitors; Animals; Antineoplasti

2003
Importance of vesicle proteins in the diagnosis and treatment of neuroendocrine tumors.
    Annals of the New York Academy of Sciences, 2004, Volume: 1014

    Topics: 3-Iodobenzylguanidine; Adenocarcinoma; Adrenal Gland Neoplasms; Adrenergic Uptake Inhibitors; Biopsy

2004
Hypertension: its management and investigation.
    The Medical journal of Australia, 1967, Sep-16, Volume: 2, Issue:12

    Topics: Aortic Coarctation; Cushing Syndrome; Electrocardiography; Female; Glomerulonephritis; Humans; Hyper

1967
Histochemical studies on catecholamines (with special reference to the paraganglion).
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1967, Jul-01, Volume: 36, Issue:4

    Topics: Adult; Animals; Catecholamines; Chlorpromazine; Chromaffin System; Female; Ganglia, Spinal; Histocyt

1967
Detection and regulation of the tyrosine hydroxylase mRNA levels in rat adrenal medulla and brain tissues.
    Cold Spring Harbor symposia on quantitative biology, 1983, Volume: 48 Pt 1

    Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Animals; Brain; Cell Line; Locus Coeruleus; Male; Pheochro

1983
Characterization of the monoamine uptake system in catecholamine storage vesicles isolated from a pheochromocytoma taken from a child.
    Biochemical pharmacology, 1984, Jul-15, Volume: 33, Issue:14

    Topics: Adenosine Triphosphate; Adolescent; Adrenal Gland Neoplasms; Biogenic Amines; Carbonyl Cyanide m-Chl

1984
Sustained stimulation of rat adrenal chromaffin cell proliferation by reserpine.
    Toxicology and applied pharmacology, 1995, Volume: 135, Issue:2

    Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Animals; Bromodeoxyuridine; Cell Count; Cell Division; Epi

1995
Vasopressor activities of N-terminal fragments of adrenomedullin in anesthetized rat.
    Biochemical and biophysical research communications, 1996, Feb-06, Volume: 219, Issue:1

    Topics: Adrenal Gland Neoplasms; Adrenomedullin; Anesthesia, General; Animals; Blood Pressure; Consciousness

1996
Comparative studies of chromaffin cell proliferation in the adrenal medulla of rats and mice.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1997, Volume: 35, Issue:2

    Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Animals; Antihypertensive Agents; Antimetabolites; Bromode

1997
Pheochromocytoma cell lines from heterozygous neurofibromatosis knockout mice.
    Cell and tissue research, 2000, Volume: 302, Issue:3

    Topics: Adrenal Gland Neoplasms; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Basic

2000
Hypertensive emergencies.
    The Medical clinics of North America, 1979, Volume: 63, Issue:1

    Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Brain Diseases

1979
Release, storage and uptake of catecholamines by a clonal cell line of nerve growth factor (NGF) responsive pheo-chromocytoma cells.
    Brain research, 1977, Jul-01, Volume: 129, Issue:2

    Topics: Animals; Catecholamines; Cations, Divalent; Clone Cells; Cocaine; Desipramine; Dinitrophenols; Dopam

1977
Release of (3H)norepinephrine from a clonal line of pheochromocytoma cells (PC12) by nicotinic cholinergic stimulation.
    Brain research, 1977, Dec-23, Volume: 138, Issue:3

    Topics: Animals; Atropine; Calcium; Clone Cells; Dimethylphenylpiperazinium Iodide; Dose-Response Relationsh

1977
[Therapy of hypertensive crisis].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Acute Disease; Adrenal Gland Neoplasms; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazine

1977
Prolonged survival in a patient with pulmonary metastases of a malignant pheochromocytoma.
    The Netherlands journal of medicine, 1978, Volume: 21, Issue:6

    Topics: Adrenal Gland Neoplasms; Adult; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Middle Ag

1978
[Therapy of hypertensive crises].
    Fortschritte der Medizin, 1977, Apr-21, Volume: 95, Issue:15

    Topics: Acute Disease; Adrenal Gland Neoplasms; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazine

1977
Long lasting increase in neuropeptide Y gene expression in rat adrenal gland with reserpine treatment: positive regulation of transsynaptic activation and membrane depolarization.
    Molecular pharmacology, 1990, Volume: 38, Issue:5

    Topics: Actins; Adrenal Gland Neoplasms; Adrenal Glands; Animals; Blotting, Northern; Cerebral Cortex; Chrom

1990
Rat dopamine beta-hydroxylase: molecular cloning and characterization of the cDNA and regulation of the mRNA by reserpine.
    Journal of neuroscience research, 1990, Volume: 25, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Amino Acid Sequence; Animals; Base Sequence; DNA; Dopamine

1990
PC12 cells: a model system for studying drug effects on dopamine synthesis and release.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 286, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Regulation of GTP cyclohydrolase I and dihydropteridine reductase in rat pheochromocytoma PC 12 cells.
    Journal of enzyme inhibition, 1989, Volume: 3, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Gland Neoplasms; Animal

1989
Effect of apomorphine, alpha-methylparatyrosine, haloperidol and reserpine on DOPA production in clonal cell lines (PC-12 and N1E-115).
    Biochemical pharmacology, 1985, Apr-01, Volume: 34, Issue:7

    Topics: Adrenal Gland Neoplasms; alpha-Methyltyrosine; Animals; Apomorphine; Cell Line; Dihydroxyphenylalani

1985
Structure of catecholamine secretory vesicles from PC12 cells.
    Journal of neurochemistry, 1985, Volume: 45, Issue:4

    Topics: Adrenal Gland Neoplasms; Animals; Catecholamines; Cell Line; Centrifugation, Density Gradient; Cytop

1985
[Hypertensive emergencies].
    Der Internist, 1974, Volume: 15, Issue:3

    Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies;

1974
[Surgery in hypertension (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1974, Mar-22, Volume: 116, Issue:12

    Topics: Adrenal Gland Neoplasms; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Pheochromocyto

1974
[Therapy of phenochromocytoma].
    Deutsche medizinische Wochenschrift (1946), 1971, Jan-15, Volume: 96, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Humans; Neoplasm

1971
[Therapy of pheochromocytoma].
    Minerva medica, 1972, Jun-27, Volume: 63, Issue:49

    Topics: Adrenergic beta-Antagonists; Antineoplastic Agents; Female; Humans; Hypnotics and Sedatives; Phenoxy

1972
[Diagnosis and immediate therapy of the endocrine crisis].
    Der Internist, 1970, Volume: 11, Issue:2

    Topics: Adrenal Insufficiency; Diabetic Coma; Emergencies; Endocrine System Diseases; Glucose; Humans; Hydro

1970
[Therapy of hypertension].
    Die Medizinische Welt, 1971, Jan-16, Volume: 3

    Topics: Adrenal Gland Neoplasms; Aniline Compounds; Antihypertensive Agents; Diuretics; Female; Guanethidine

1971
The role of catecholamines in producing arrhythmias.
    The American journal of the medical sciences, 1971, Volume: 262, Issue:1

    Topics: Anesthetics; Antidepressive Agents; Arrhythmias, Cardiac; Atropine; Catecholamines; Digitalis Glycos

1971
[The hypertensive crisis. Urgent therapeutic measures].
    Therapeutische Umschau. Revue therapeutique, 1967, Volume: 24, Issue:5

    Topics: Antihypertensive Agents; Diazoxide; Drug Synergism; Female; Guanethidine; Humans; Hypertension; Male

1967
[Clinical studies on urinary metanephrine and normetanephrine in various endocrine diseases. 2. Clinical studies on urinary metanephrine and normetanephrine in patients with pheochromyocytoma and a patient with neuroblastoma].
    Naika hokan. Japanese archives of internal medicine, 1968, Volume: 15, Issue:9

    Topics: Adult; Bretylium Compounds; Catecholamines; Child, Preschool; Female; Histamine; Humans; Male; Methy

1968
Pheochromocytoma associated with pregnancy. Specialty team management and review.
    American journal of obstetrics and gynecology, 1969, May-15, Volume: 104, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Anesthesia, Intravenous; Female; Fetal Death; Humans; Hypertension;

1969