reserpine has been researched along with Neuroendocrine Tumors in 2 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Neuroendocrine Tumors: Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the VMAT-expressing NE tumour cell lines GOT1 and BON and in VMAT-expressing primary NE tumour cell cultures (carcinoids, n=4 and pheochromocytomas, n=4), reserpine significantly reduced the uptake of (123)I-MIBG." | 3.72 | Uptake of meta-iodobenzylguanidine in neuroendocrine tumours is mediated by vesicular monoamine transporters. ( Ahlman, H; Bernhardt, P; Forssell-Aronsson, E; Johanson, V; Kölby, L; Levin-Jakobsen, AM; Nilsson, O; Wängberg, B, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kölby, L | 2 |
| Bernhardt, P | 2 |
| Levin-Jakobsen, AM | 1 |
| Johanson, V | 1 |
| Wängberg, B | 1 |
| Ahlman, H | 2 |
| Forssell-Aronsson, E | 2 |
| Nilsson, O | 2 |
| Jakobsen, AM | 1 |
2 other studies available for reserpine and Neuroendocrine Tumors
| Article | Year |
|---|---|
Uptake of meta-iodobenzylguanidine in neuroendocrine tumours is mediated by vesicular monoamine transporters.
Topics: 3-Iodobenzylguanidine; Adrenal Gland Neoplasms; Adrenergic Uptake Inhibitors; Animals; Antineoplasti | 2003 |
Importance of vesicle proteins in the diagnosis and treatment of neuroendocrine tumors.
Topics: 3-Iodobenzylguanidine; Adenocarcinoma; Adrenal Gland Neoplasms; Adrenergic Uptake Inhibitors; Biopsy | 2004 |