reserpine has been researched along with Nervous System Disorders in 23 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response curves for the effects of PPA and amphetamine (administered IP, 15 min presession) were then determined (ED50 = 35." | 1.28 | Evaluation of the pharmacological similarities between phenylpropanolamine and amphetamine: effects on schedule-controlled behavior. ( Jarvis, MF; Wagner, GC, 1990) |
| " The central monoamine stores of rats were significantly decreased with reserpine (5 mg/kg) prior to toxic injections of MDMA." | 1.28 | Reserpine does not prevent 3,4-methylenedioxymethamphetamine-induced neurotoxicity in the rat. ( Hekmatpanah, CR; McKenna, DJ; Peroutka, SJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (65.22) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (8.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bruns, RF | 1 |
| Mitchell, SN | 1 |
| Wafford, KA | 1 |
| Harper, AJ | 1 |
| Shanks, EA | 1 |
| Carter, G | 1 |
| O'Neill, MJ | 1 |
| Murray, TK | 1 |
| Eastwood, BJ | 1 |
| Schaus, JM | 1 |
| Beck, JP | 1 |
| Hao, J | 1 |
| Witkin, JM | 1 |
| Li, X | 1 |
| Chernet, E | 1 |
| Katner, JS | 1 |
| Wang, H | 1 |
| Ryder, JW | 1 |
| Masquelin, ME | 1 |
| Thompson, LK | 1 |
| Love, PL | 1 |
| Maren, DL | 1 |
| Falcone, JF | 1 |
| Menezes, MM | 1 |
| Zhang, L | 1 |
| Yang, CR | 1 |
| Svensson, KA | 1 |
| Shah, A | 1 |
| Garzon-Muvdi, T | 1 |
| Mahajan, R | 1 |
| Duenas, VJ | 1 |
| Quiñones-Hinojosa, A | 1 |
| BENTE, D | 2 |
| FLUGEL, F | 2 |
| MORTON, HG | 2 |
| WARSON, SR | 2 |
| KLINE, NS | 1 |
| SAUNDERS, JC | 1 |
| MACKIEWICZ, J | 2 |
| GERSHON, S | 1 |
| REID, AA | 1 |
| CAZZULLO, CL | 1 |
| LAMBROS, VS | 1 |
| STOLL, WA | 1 |
| Tripathi, M | 1 |
| Verma, M | 1 |
| Palit, G | 3 |
| Shanker, K | 3 |
| Mikhaĭlenko, AA | 1 |
| Odinak, MM | 1 |
| Ivanov, IuS | 1 |
| Kotel'nikov, SA | 1 |
| Semin, GF | 1 |
| Shustov, EB | 1 |
| Burnstock, G | 1 |
| Singh, V | 2 |
| Srivastava, VK | 2 |
| Khanna, R | 1 |
| Schmidt, CJ | 1 |
| Black, CK | 1 |
| Taylor, VL | 1 |
| Wagner, GC | 1 |
| Jarvis, MF | 1 |
| Hekmatpanah, CR | 1 |
| McKenna, DJ | 1 |
| Peroutka, SJ | 1 |
| Debreceni, L | 1 |
| Tényi, I | 1 |
| Csete, B | 1 |
| Csonka-Takács, L | 1 |
| DeQuattro, V | 1 |
| Miura, Y | 1 |
| Gelmetti, P | 1 |
| Häfner, H | 1 |
| Schliack, E | 1 |
| Zenz, H | 1 |
2 reviews available for reserpine and Nervous System Disorders
| Article | Year |
|---|---|
Animal models of neurological disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic Agents; Amyloid beta-Protein Precursor; Ani | 2010 |
Morphological changes produced by drugs acting on the autonomic nervous system.
Topics: 5,6-Dihydroxytryptamine; 5,7-Dihydroxytryptamine; Animals; Antihypertensive Agents; Autonomic Nervou | 1979 |
21 other studies available for reserpine and Nervous System Disorders
| Article | Year |
|---|---|
Preclinical profile of a dopamine D1 potentiator suggests therapeutic utility in neurological and psychiatric disorders.
Topics: Animals; Antipsychotic Agents; Blinking; Corpus Striatum; Disease Models, Animal; Dopamine Agents; I | 2018 |
[Akinetic-abulic syndrome and its importance in pharmacological-psychiatric research].
Topics: Chlorpromazine; Humans; Mental Disorders; Nervous System Diseases; Research; Reserpine; Syndrome | 1956 |
[Akinetic-abulic syndrome and its importance in pharmacological-psychiatric research].
Topics: Chlorpromazine; Humans; Mental Disorders; Nervous System Diseases; Research; Reserpine; Syndrome | 1956 |
[Akinetic-abulic syndrome and its importance in pharmacological-psychiatric research].
Topics: Chlorpromazine; Humans; Mental Disorders; Nervous System Diseases; Research; Reserpine; Syndrome | 1956 |
[Akinetic-abulic syndrome and its importance in pharmacological-psychiatric research].
Topics: Chlorpromazine; Humans; Mental Disorders; Nervous System Diseases; Research; Reserpine; Syndrome | 1956 |
Control study on reserpine in small group of children with neurologic disorders.
Topics: Child; Infant; Mental Disorders; Nervous System Diseases; Reserpine | 1957 |
Control study on reserpine in small group of children with neurologic disorders.
Topics: Child; Infant; Mental Disorders; Nervous System Diseases; Reserpine | 1957 |
Control study on reserpine in small group of children with neurologic disorders.
Topics: Child; Infant; Mental Disorders; Nervous System Diseases; Reserpine | 1957 |
Control study on reserpine in small group of children with neurologic disorders.
Topics: Child; Infant; Mental Disorders; Nervous System Diseases; Reserpine | 1957 |
Reserpine in psychiatric and neurologic disorders.
Topics: Electroconvulsive Therapy; Humans; Mental Disorders; Nervous System Diseases; Psychotherapy; Reserpi | 1957 |
AN EXPERIMENTAL STUDY OF THE NEUROPATHOLOGICAL AND TOXICOLOGICAL EFFECTS OF CHLORPROMAZINE AND RESERPINE.
Topics: Cerebellum; Cerebrovascular Circulation; Chlorpromazine; Guinea Pigs; Nervous System Diseases; Parki | 1964 |
CLINICAL AND NEUROPATHOLOGICAL INVESTIGATIONS OF FOUR CASES OF HUNTINGTON'S CHOREA TREATED WITH HIGH DOSES OF RESERPINE.
Topics: Basal Ganglia; Chorea; Drug Therapy; Ganglia; Humans; Huntington Disease; Medulla Oblongata; Nervous | 1965 |
[THE CHEMOTHERAPY OF ANXIETY].
Topics: Anxiety; Chlorprothixene; Depression; Drug Therapy; Humans; Nervous System Diseases; Reserpine; Schi | 1965 |
RESERPINE in the treatment of neuropsychiatric, neurological, and related clinical problems.
Topics: Counseling; Humans; Mental Disorders; Nervous System Diseases; Psychotherapy; Reserpine; Secologanin | 1955 |
The use of reserpine in certain neurological disorders: organic convulsive states, enuresis, and head injuries.
Topics: Craniocerebral Trauma; Enuresis; Nervous System Diseases; Reserpine; Secologanin Tryptamine Alkaloid | 1955 |
[Conference on Reserpine in the treatment of Neuropsychiatric, Neurological, and related Clinical problems, New York, 3. und 4. February 1955].
Topics: Antihypertensive Agents; Mental Disorders; Nervous System Diseases; New York; Psychiatry; Reserpine; | 1955 |
Antipyrine congeners as antidepressant agents.
Topics: Amphetamine; Animals; Antidepressive Agents; Antipyrine; Behavior, Animal; Female; Imipramine; Letha | 1993 |
[Patterns in the change of the evoked skin autonomic potential in nervous system diseases].
Topics: Adolescent; Adrenergic Agents; Adult; Autonomic Nervous System; Evoked Potentials; GABA Agents; gamm | 1997 |
Coumarin congeners as antidepressants.
Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Coumarins; Drug Synergism; Female; Le | 1992 |
Synthesis and pharmacological evaluation of some phenothiazines as antidepressants.
Topics: Amphetamine; Animals; Antidepressive Agents; Depression; Drug Synergism; Female; Male; Mice; Nervous | 1992 |
Antagonism of the neurotoxicity due to a single administration of methylenedioxymethamphetamine.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; | 1990 |
Evaluation of the pharmacological similarities between phenylpropanolamine and amphetamine: effects on schedule-controlled behavior.
Topics: alpha-Methyltyrosine; Amphetamine; Animals; Conditioning, Operant; Male; Methyltyrosines; Nervous Sy | 1990 |
Reserpine does not prevent 3,4-methylenedioxymethamphetamine-induced neurotoxicity in the rat.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Cerebral Cortex; Corpus Striatum; Designer Dru | 1989 |
The effect of dehydrobenzperidol, chlorpromazine and reserpine on the pituitary-adrenal system in human.
Topics: Adrenocorticotropic Hormone; Arthritis, Rheumatoid; Benperidol; Chlorpromazine; Dexamethasone; Human | 1971 |
Neurogenic factors in human hypertension: mechanism or myth?
Topics: Angiotensin II; Blood Pressure; Catecholamines; Chemical Phenomena; Chemistry; Dihydroxyphenylalanin | 1973 |
[Rauwolfia and nervous diseases (historical notes)].
Topics: History, 15th Century; History, 16th Century; History, 17th Century; History, 18th Century; History, | 1968 |
[The high dosage reserpine cure in the treatment of chronic schizophrenics. A clinical and statistical analysis].
Topics: Adolescent; Adult; Age Factors; Aged; Autonomic Nervous System; Chronic Disease; Female; Humans; Mal | 1968 |