reserpine has been researched along with Nephrosclerosis in 4 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Nephrosclerosis: Hardening of the KIDNEY due to infiltration by fibrous connective tissue (FIBROSIS), usually caused by renovascular diseases or chronic HYPERTENSION. Nephrosclerosis leads to renal ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " After 4 weeks of DOCA-salt hypertension, rats were either killed (n = 6), or treated with a non-hypotensive dose of spironolactone (n = 7) or triple therapy (hydrochlorothiazide, reserpine and hydralazine, n = 8) to normalize blood pressure or with vehicle (n = 19) for two further weeks." | 3.74 | Blood pressure versus direct mineralocorticoid effects on kidney inflammation and fibrosis in DOCA-salt hypertension. ( Cordasic, N; Hartner, A; Hilgers, KF; Klanke, B; Schmieder, RE; Veelken, R, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klanke, B | 2 |
| Cordasic, N | 1 |
| Hartner, A | 2 |
| Schmieder, RE | 1 |
| Veelken, R | 1 |
| Hilgers, KF | 2 |
| Westhoff, JH | 1 |
| Steinbach, MP | 1 |
| Amann, K | 1 |
| Melk, A | 1 |
| Spach, MO | 1 |
| Imbs, JL | 1 |
| Schwartz, J | 1 |
| Girndt, J | 1 |
| Kramer, P | 1 |
| Scheler, F | 1 |
4 other studies available for reserpine and Nephrosclerosis
| Article | Year |
|---|---|
Blood pressure versus direct mineralocorticoid effects on kidney inflammation and fibrosis in DOCA-salt hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Dise | 2008 |
Hypertension induces somatic cellular senescence in rats and humans by induction of cell cycle inhibitor p16INK4a.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Antihypertensive Ag | 2008 |
[Malignant nephroangiosclerosis. Development and treatment].
Topics: Adult; Aniline Compounds; Antihypertensive Agents; Cerebrovascular Disorders; Diagnosis, Differentia | 1972 |
[Severe hypertension with cardiac failure and nephrosclerosis after oral contraceptives (author's transl)].
Topics: Adult; Antihypertensive Agents; Cardiac Catheterization; Contraceptives, Oral; Digoxin; Dyspnea; Ele | 1974 |