reserpine has been researched along with Necrosis in 35 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Excessive doses of pancreatic enzymes in combination with agents that increased intestinal permeability (oleic acid, reserpine) were associated with intestinal eosinophilia and necrosis of the jejunoileal muscle layer and inflammatory nodules in the liver, which increased with duration of insult." | 3.70 | The effect of intestinal permeability on pancreatic enzyme-induced enteropathy in the rat. ( Arango, V; Fusaro, A; Kimura, RE; Lloyd-Still, JD; Uhing, MR, 1998) |
| " A recent clinical report, however, suggested that intraarterial injection of reserpine was affective in limiting tissue necrosis." | 3.68 | The role of intraarterial vasodilators in the treatment of inadvertent intraarterial injection injuries. ( Crawford, CR; Terranova, WA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (88.57) | 18.7374 |
| 1990's | 4 (11.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| RAAB, W | 1 |
| JASMIN, G | 1 |
| BAJUSZ, E | 1 |
| VASKO, JS | 1 |
| BROCKMAN, SK | 1 |
| MCQUIGGAN, MC | 1 |
| OLIVER, WJ | 1 |
| LITTLER, ER | 1 |
| CERNY, JC | 1 |
| PETZOLD, H | 1 |
| ZIMMERMANN, S | 1 |
| AMER, S | 1 |
| WENZEL, DG | 1 |
| STARK, LG | 1 |
| Gál, G | 2 |
| Leszkovszky, G | 1 |
| Lendvai, J | 1 |
| Selye, H | 1 |
| Feld, LG | 1 |
| Van Liew, JB | 1 |
| Brentjens, JR | 1 |
| Boylan, JW | 1 |
| Toombs, CF | 1 |
| Wiltse, AL | 1 |
| Shebuski, RJ | 1 |
| Lloyd-Still, JD | 1 |
| Uhing, MR | 1 |
| Arango, V | 1 |
| Fusaro, A | 1 |
| Kimura, RE | 1 |
| Boyko, WJ | 1 |
| Galabru, CK | 1 |
| McGeer, EG | 1 |
| McGeer, PL | 1 |
| Allen, JD | 1 |
| Pantridge, JF | 1 |
| Patton, JN | 1 |
| Tanabe, Y | 1 |
| Kagawa, Y | 1 |
| Takada, M | 1 |
| Yamada, H | 1 |
| Sakata, K | 1 |
| Rawe, SE | 1 |
| Roth, RH | 1 |
| Collins, WF | 1 |
| Bruce, JR | 1 |
| Weise, HJ | 1 |
| Carter, MK | 1 |
| Kellerhals, B | 1 |
| Schlageter, JS | 1 |
| Zheng, JW | 1 |
| Crawford, CR | 1 |
| Terranova, WA | 1 |
| Schweitzer, IL | 1 |
| Peters, RL | 1 |
| McCracken, MD | 1 |
| Carlton, WW | 1 |
| Tuite, J | 1 |
| Clasen, RA | 1 |
| Pandolfi, S | 1 |
| Casey, D | 1 |
| Schwartz, DT | 1 |
| Buda, JA | 1 |
| Sommers, SC | 1 |
| Leszkovszky, GP | 1 |
| Zbinden, G | 1 |
| Moe, RA | 1 |
| Osterholm, JL | 1 |
| Mathews, GJ | 1 |
| Irvin, JD | 1 |
| Calesnick, B | 1 |
| Vander Ark, GD | 1 |
| Norton, LW | 1 |
| Pomerantz, M | 1 |
| Ho, EC | 1 |
| Moss, AJ | 1 |
| Creasey, NH | 1 |
| Allenby, AC | 1 |
| Schock, C | 1 |
| Hawkins, WE | 1 |
| Clower, BR | 4 |
| McNair, JL | 1 |
| Sanford, RA | 1 |
| Srinivasan, S | 1 |
| Srinivasan, U | 1 |
| Balwani, H | 1 |
| Douglas, BH | 2 |
| Carrier, O | 1 |
| Ascanio, G | 1 |
| Barrera, F | 1 |
| Lautsch, EV | 1 |
| Oppenheimer, MJ | 1 |
2 reviews available for reserpine and Necrosis
| Article | Year |
|---|---|
NEUROGENIC MULTIFOCAL DESTRUCTION OF MYOCARDIAL TISSUE (PATHOGENIC MECHANISM AND ITS PREVENTION).
Topics: Adrenal Cortex Hormones; Catecholamines; Epinephrine; Heart Diseases; Hypoxia; Myocardial Infarction | 1963 |
[Prevention and treatment of flap necrosis by drugs].
Topics: Animals; Chlorpromazine; Graft Survival; Humans; Necrosis; Pentoxifylline; Reserpine; Skin; Surgical | 1990 |
33 other studies available for reserpine and Necrosis
| Article | Year |
|---|---|
[PATHOGENIC STUDY OF CARDIAC, RENAL AND MUSCULAR LESIONS INDUCED IN THE RAT BY METHOXAMINE AND METARAMINOL].
Topics: Adrenalectomy; Coronary Vessels; Histamine Release; Infarction; Ischemia; Kidney; Metaraminol; Metho | 1964 |
MASSIVE VENOUS OCCLUSION OF THE LOWER EXTREMITY.
Topics: Animals; Blood Transfusion; Cyanosis; Dogs; Edema; Gangrene; Guanethidine; Iliac Vein; Lower Extremi | 1964 |
HEMOLYTIC UREMIC SYNDROME.
Topics: Acute Kidney Injury; Anemia, Hemolytic; Child; Diagnosis; Dialysis; Diarrhea; Drug Therapy; Glomerul | 1965 |
[THE EFFECT OF DIFFERENT SUBSTANCES ON ACUTE CARBON TETRACHLORIDE NECROSIS OF THE RAT LIVER].
Topics: Aspartate Aminotransferases; Blood Chemical Analysis; Carbon Tetrachloride; Carbon Tetrachloride Poi | 1965 |
EFFECT OF NICOTINE ON CARDIAC NECROSIS INDUCED BY CORTICOSTEROID-ELECTROLYTE-STRESS.
Topics: Adrenal Cortex Hormones; Desoxycorticosterone; Dexamethasone; Humans; Mecamylamine; Myocardial Infar | 1965 |
Quantitative evaluation of morphologic changes in experimentally induced myocardial necrosis.
Topics: Animals; Guanethidine; Heart Diseases; Iproniazid; Isoproterenol; Male; Monoamine Oxidase Inhibitors | 1966 |
Acute cutaneous necrosis following sensitization by heterologous blood.
Topics: Acetates; Animals; Blood Group Incompatibility; Blood Transfusion; Cats; Cattle; Chlorpromazine; Cri | 1967 |
Renal lesions and proteinuria in the spontaneously hypertensive rat made normotensive by treatment.
Topics: Age Factors; Animals; Arteriosclerosis; Blood Pressure; Chlorothiazide; Hydralazine; Hypertension; K | 1981 |
Ischemic preconditioning fails to limit infarct size in reserpinized rabbit myocardium. Implication of norepinephrine release in the preconditioning effect.
Topics: Animals; Blood Pressure; Female; Heart Rate; Male; Myocardial Infarction; Myocardial Stunning; Myoca | 1993 |
The effect of intestinal permeability on pancreatic enzyme-induced enteropathy in the rat.
Topics: Animals; Cell Membrane Permeability; Eosinophilia; Intestinal Diseases; Intestines; Lipase; Liver; N | 1998 |
Thalamic injections of kainic acid produce myocardial necrosis.
Topics: Animals; Hydroxydopamines; Kainic Acid; Male; Myocardium; Necrosis; Norepinephrine; Pyrrolidines; Ra | 1979 |
Autonomic nervous activity and myocardial necrosis after DC shocks from cardiac defibrillators [proceedings].
Topics: Animals; Dogs; Electric Countershock; Heart; Myocardium; Necrosis; Propranolol; Reserpine | 1979 |
[Ultrastructural changes in cerebral arterial wall and cerebral vasopasm--an experimental study (author's transl)].
Topics: Animals; Basilar Artery; Dogs; Ischemic Attack, Transient; Muscle, Smooth; Necrosis; Norepinephrine; | 1978 |
Norepinephrine levels in experimental spinal cord trauma. Part 2: Histopathological study of hemorrhagic necrosis.
Topics: Animals; Blood Pressure; Cats; Hemorrhage; Methyltyrosines; Necrosis; Norepinephrine; Phenoxybenzami | 1977 |
The effects of reserpine on renal necrosis and urinary catecholamines of choline-deficient rats.
Topics: Animals; Catecholamines; Choline Deficiency; Kidney Diseases; Male; Necrosis; Norepinephrine; Rats; | 1976 |
Cryosurgery in vasomotor rhinopathy: experimental histopathology.
Topics: Animals; Cryosurgery; Epithelium; Guinea Pigs; Nasal Mucosa; Necrosis; Reserpine; Rhinitis; Wound He | 1976 |
The role of intraarterial vasodilators in the treatment of inadvertent intraarterial injection injuries.
Topics: Animals; Arteries; Disease Models, Animal; Ear, External; Injections, Intra-Arterial; Necrosis; Rabb | 1990 |
Acute submassive hepatic necrosis due to methyldopa. A case demonstrating possible initiation of chronic liver disease.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biopsy, Needle; Chemical and Drug Induced Liver I | 1974 |
Penicillium viridicatum mycotoxicosis in the rat. IV. Attempts to modify the tissue responses.
Topics: Animals; Body Weight; Castration; Cornea; Diet; Eye; Kidney; Liver; Male; Mycotoxins; Necrosis; Peni | 1974 |
Reserpine in experimental cerebral edema: further observations.
Topics: Animals; Blood Pressure; Body Temperature; Brain Edema; Brain Injuries; Cerebral Cortex; Cerebral He | 1974 |
The effect of portacaval transposition and renal artery stenosis on the rejection of renal allografts in dogs.
Topics: Animals; Biopsy; Blood Pressure; Dogs; Edema; Endopeptidases; Hemorrhage; Histocompatibility; Humans | 1969 |
Observations on isoprenaline-induced myocardial necroses.
Topics: Animals; Guanethidine; Heart Diseases; Iproniazid; Isoproterenol; Male; Monoamine Oxidase Inhibitors | 1967 |
Pharmacological studies on heart muscle lesions induced by isoproterenol.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amides; Animals; Antihypertensive Agents; | 1969 |
Chapter 29. Anti-norepinephrine therapy against traumatic hemorrhagic necrosis of the spinal cord: preliminary report.
Topics: Animals; Bretylium Compounds; Cats; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Guan | 1973 |
The effects of brain stem compression on the heart.
Topics: Animals; Arrhythmias, Cardiac; Atropine; Blood Pressure; Bradycardia; Brain Injuries; Brain Stem; Ca | 1974 |
The syndrome of "mesenteric arteritis" following surgical repair of aortic coarctation. Report of nine cases and review of the literature.
Topics: Antihypertensive Agents; Aortic Coarctation; Arteritis; Child; Child, Preschool; Female; Humans; Hyd | 1972 |
Mechanism of action of accelerants. The effect of cutaneously-applied penetration accelerants on the skin circulation of the rat.
Topics: Amines; Animals; Capillary Permeability; Cold Temperature; Dimethyl Sulfoxide; Ear; Epinephrine; Fur | 1971 |
Myocardial damage after head trauma and simulated intracranial haemorrhage in mice: the role of the autonomic nervous system.
Topics: Adrenal Glands; Adrenalectomy; Animals; Atropine; Autonomic Nervous System; Cardiomyopathies; Catech | 1971 |
The effect of reserpine pretreatment on myocardial damage associated with simulated intracranial hemorrhage in mice.
Topics: Animals; Cardiomyopathies; Cerebral Hemorrhage; Female; Mice; Myocardium; Necrosis; Reserpine; Subar | 1970 |
Effect of thyroxine, reerpine and serotonin on allyl alcohol induced hepatotoxicity in rats.
Topics: Alanine Transaminase; Alcohols; Animals; Body Temperature; Injections, Intraperitoneal; Liver; Male; | 1970 |
Protection by reserpine of carbon tetrachloride-induced hepatic necrosis.
Topics: Animals; Calcium; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Histocytoche | 1968 |
Hepatotoxic effect of carbon tetrachloride during pregnancy.
Topics: Animals; Carbon Tetrachloride Poisoning; Female; Inflammation; Injections, Subcutaneous; Liver; Necr | 1968 |
Role of reflexes following myocardial necrobiosis.
Topics: Animals; Atropine; Collateral Circulation; Dogs; Femoral Artery; Hydrocarbons, Halogenated; Myocardi | 1965 |