reserpine has been researched along with Myocardial Ischemia in 9 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reserpine treatment did not significantly alter pre- or post-ischaemic adenosine efflux." | 1.32 | Enhanced adenosine A(2B) mediated coronary response in reserpinised rat heart. ( Harrison, GJ; Headrick, JP; Rose'Meyer, RB, 2003) |
| "Reserpine pretreatment did not affect the response to ischaemia or to preconditioning, although LDH release tended to be greater than in normal hearts, especially in the non-preconditioned group." | 1.29 | Endogenous catecholamines are not necessary for ischaemic preconditioning in the isolated perfused rat heart. ( Baird, AJ; Dzwonczyk, S; Grover, GJ; Murray, HN; Sleph, PG; Weselcouch, EO, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rose'Meyer, RB | 1 |
| Harrison, GJ | 1 |
| Headrick, JP | 1 |
| Weselcouch, EO | 1 |
| Baird, AJ | 1 |
| Sleph, PG | 1 |
| Dzwonczyk, S | 1 |
| Murray, HN | 1 |
| Grover, GJ | 1 |
| Rump, AF | 1 |
| Picke, D | 1 |
| Rösen, R | 1 |
| Klaus, W | 1 |
| Rongen, GA | 1 |
| Smits, P | 1 |
| Thien, T | 1 |
| Vander Heide, RS | 1 |
| Schwartz, LM | 1 |
| Jennings, RB | 1 |
| Reimer, KA | 1 |
| Sharma, A | 1 |
| Singh, M | 1 |
| Chen, H | 1 |
| Higashino, H | 1 |
| Maeda, K | 1 |
| Zhang, Z | 1 |
| Ohta, Y | 1 |
| Wang, Z | 1 |
| Su, DF | 1 |
| Yuan, WJ | 1 |
| Abete, P | 1 |
| Testa, G | 1 |
| Ferrara, N | 1 |
| De Santis, D | 1 |
| Capaccio, P | 1 |
| Viati, L | 1 |
| Calabrese, C | 1 |
| Cacciatore, F | 1 |
| Longobardi, G | 1 |
| Condorelli, M | 1 |
| Napoli, C | 1 |
| Rengo, F | 1 |
| Cohen, JD | 1 |
9 other studies available for reserpine and Myocardial Ischemia
| Article | Year |
|---|---|
Enhanced adenosine A(2B) mediated coronary response in reserpinised rat heart.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Flavins; In Vit | 2003 |
Endogenous catecholamines are not necessary for ischaemic preconditioning in the isolated perfused rat heart.
Topics: Animals; Catecholamines; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Ischemia; | 1995 |
Effects of propranolol, pindolol and carteolol on acute regional myocardial ischemia in isolated rabbit hearts.
Topics: Adrenergic beta-Antagonists; Animals; Carteolol; Catecholamines; Coronary Circulation; Electric Stim | 1993 |
Role of norepinephrine in ischemic preconditioning in rabbit myocardium.
Topics: Animals; Myocardial Infarction; Myocardial Ischemia; Norepinephrine; Phenylephrine; Rabbits; Reserpi | 1994 |
Effect of catecholamine depletion on myocardial infarct size in dogs: role of catecholamines in ischemic preconditioning.
Topics: Adrenergic Uptake Inhibitors; Animals; Collateral Circulation; Dogs; Female; Male; Myocardial Infarc | 1995 |
Possible mechanism of cardioprotective effect of angiotensin preconditioning in isolated rat heart.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiovascular Agents; Colchicine; Creatine Kinase; Female; | 2000 |
Reduction of cardiac norepinephrine improves postischemic heart function in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Cardiac Output; Cardiomegaly; Coronary Circulation; Creatine Kinase; Heart Rate; Hemodynami | 2001 |
Cardioprotective effect of ischemic preconditioning is preserved in food-restricted senescent rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Aging; Animals; Blood Flow Velocity; Bod | 2002 |
Abnormal electrocardiograms and cardiovascular risk: role of silent myocardial ischemia. Evidence from MRFIT.
Topics: Adult; Antihypertensive Agents; Chlorthalidone; Cholesterol, Dietary; Coronary Disease; Electrocardi | 1992 |