Page last updated: 2024-11-06

reserpine and Movement Disorders

reserpine has been researched along with Movement Disorders in 95 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.

Research Excerpts

ExcerptRelevanceReference
"Tetrabenazine (TBZ) is a monoamine-depleting agent initially studied in the 1950s and currently approved by the US Food and Drug Administration for the treatment of chorea in Huntington's disease."6.46Tetrabenazine, a monoamine-depleting drug used in the treatment of hyperkinetic movement disorders. ( Guay, DR, 2010)
"Reserpine treatment increased VCMs and decreased locomotor activity."5.39Effect of Hypericum perforatum on different models of movement disorders in rats. ( Athayde, ML; Boligon, AA; Busanello, A; Fachinetto, R; Leal, CQ; Reckziegel, P; Reis, EM; Röpke, J; Wagner, C, 2013)
"This is a review of reserpine, haloperidol, and various phenothiazines that produce parkinsonism and other movement disorders."4.78Drug-induced parkinsonism and other movement disorders. ( Ross, RT, 1990)
" The mothers of three infants had been on medication (either alpha-methyl dopa, reserpine or haloperidol) during pregnancy, whereas the mothers of the other three infants took no medication during pregnancy."3.71Rapid-eye-movement sleep in jittery infants. ( Iwakawa, Y; Kohyama, J; Shimohira, M, 2002)
"Tetrabenazine (TBZ) is a monoamine-depleting agent initially studied in the 1950s and currently approved by the US Food and Drug Administration for the treatment of chorea in Huntington's disease."2.46Tetrabenazine, a monoamine-depleting drug used in the treatment of hyperkinetic movement disorders. ( Guay, DR, 2010)
"Reserpine treatment (1mg/kgs."1.42(-) Epigallocatechin-3-gallate attenuates reserpine-induced orofacial dyskinesia and oxidative stress in rat striatum. ( Chang, KC; Lin, RF; Soung, HS; Tsai, CC; Tseng, HC; Wang, MH, 2015)
"Reserpine treatment increased VCMs and decreased locomotor activity."1.39Effect of Hypericum perforatum on different models of movement disorders in rats. ( Athayde, ML; Boligon, AA; Busanello, A; Fachinetto, R; Leal, CQ; Reckziegel, P; Reis, EM; Röpke, J; Wagner, C, 2013)
"Here we used the animal models of extrapyramidal disorders cited above, which were performed in two distinct experiments: orofacial dyskinesia (OD)/catalepsy induced by acute reserpine and subchronic haloperidol after (experiment 1) and before (experiment 2) oral treatment with pecan shell aqueous extract (AE), a natural and promissory antioxidant."1.37Comparative study between two animal models of extrapyramidal movement disorders: prevention and reversion by pecan nut shell aqueous extract. ( Barcelos, RC; Benvegnú, DM; Boufleur, N; Bürger, ME; Dias, VT; Dolci, GS; Pase, CS; Reckziegel, P; Segat, HJ; Trevizol, F, 2011)
"Reserpine treated rats significantly developed vacuous chewing movements and tongue protrusions however, coadministration of Hibiscus rosa sinensis roots extract (100, 200 and 300 mg/kg, per orally) attenuated the effects."1.35Effect of Hibiscus rosa sinensis on reserpine-induced neurobehavioral and biochemical alterations in rats. ( Dwivedi, S; Kawale, LA; Nade, VS; Upasani, CD; Yadav, AV, 2009)
" The ip LD50 of CPA was found to be 13 +/- 0."1.27Toxicity and neuropharmacology of cyclopiazonic acid. ( Cole, RJ; Dorner, JW; Nishie, K, 1985)
"The syndrome was not seen after thioridazine (3-7 mg/kg)."1.26Acute dystonia as an idiosyncratic response to neuroleptics in baboons. ( Anlezark, GM; Marsden, CD; Meldrum, BS, 1977)
" The main metabolite of piribedil, S 584, had no clear-cut pharmacologic action in our hands at the dosage used."1.25Apomorphine and piribedil in rats: biochemical and pharmacologic studies. ( Barbeau, A; Butterworth, RF; Poignant, JC, 1975)
"Reserpine pretreatment potentiates turning produced by (-)-ephedrine."1.25Turning behaviour as an index of the action of amphetamines and ephedrines on central dopamine-containing neurones. ( Christie, JE; Crow, TJ, 1971)

Research

Studies (95)

TimeframeStudies, this research(%)All Research%
pre-199081 (85.26)18.7374
1990's2 (2.11)18.2507
2000's5 (5.26)29.6817
2010's7 (7.37)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reis, EM1
Röpke, J1
Busanello, A1
Reckziegel, P3
Leal, CQ1
Wagner, C1
Boligon, AA1
Athayde, ML1
Fachinetto, R1
Wang, MH1
Lin, RF1
Tseng, HC1
Soung, HS1
Chang, KC1
Tsai, CC1
Kronbauer, M1
Segat, HJ2
De David Antoniazzi, CT1
Roversi, K2
Pase, CS2
Barcelos, RC3
Burger, ME3
Aguiar, AS1
Araújo, AL1
da-Cunha, TR1
Speck, AE1
Ignácio, ZM1
De-Mello, N1
Prediger, RD1
Nade, VS1
Dwivedi, S1
Kawale, LA1
Upasani, CD1
Yadav, AV1
Guay, DR1
Benvegnú, DM2
Boufleur, N2
Pase, C1
Teixeira, AM1
Emanuelli, T1
da Rocha, JB1
Trevizol, F1
Dias, VT1
Dolci, GS1
Maxia, A1
Frau, MA1
Foddis, C1
Lancioni, MC1
Kasture, V1
Kasture, S1
FLUGEL, F2
BOURGUIGNON, A2
DELAY, J2
DENIKER, P2
LEMPERIERE, T2
GERSTENBRAND, F3
WEINGARTEN, K2
WINDLE, WF1
CAMMERMEYER, J1
JORALEMON, J1
SMART, JO1
FERINGA, ER1
MCQUILLEN, MP1
DE NEGRI, M1
GRILLO, V1
STREHL, W1
HAASE, HJ1
KORANYI, L1
ENDROECZI, E1
LISSAK, K1
MARKHAM, CH1
CLARK, WG1
WINTERS, WD1
PROSENZ, P1
HAEFNER, H1
KUTSCHER, I1
ROOS, BE1
STEG, G3
ZSCHUCKE, CF1
HUNTER, R1
EARL, CJ1
THRONICROFT, S1
BOZZI, R1
BRUNO, A1
ALLEGRANZA, A1
Kovoor, A1
Seyffarth, P1
Ebert, J1
Barghshoon, S1
Chen, CK1
Schwarz, S1
Axelrod, JD1
Cheyette, BN1
Simon, MI1
Lester, HA1
Schwarz, J1
Scheel-Krüger, J1
Randrup, A1
Chadha, A1
Sur, C1
Atack, J1
Duty, S1
Shimohira, M1
Iwakawa, Y1
Kohyama, J1
Paulson, G1
Meldrum, BS1
Anlezark, GM1
Marsden, CD6
Pappenheim, E1
Vigouret, JM1
Bürki, HR1
Jaton, AL1
Züger, PE1
Loew, DM1
Obeso, JA1
Marti-Masso, JF1
Astudillo, W1
de la Puente, E1
Carrera, N1
Poirier, LJ3
Péchadre, JC1
Larochelle, L3
Dankova, J1
Boucher, R2
Dolphin, A2
Jenner, P3
Butterworth, RF1
Poignant, JC1
Barbeau, A1
Stimmel, GL1
Clyne, KE1
Juhl, R1
Popoli, P1
Caporali, MG1
Scotti de Carolis, A1
Ross, RT1
Cooper, DR1
Marrel, C1
van de Waterbeemd, H1
Testa, B1
Frances, H1
Bulach, C1
Simon, P1
Fillion, M1
Fillion, G1
Colpaert, FC1
Nishie, K1
Cole, RJ1
Dorner, JW1
Villeneuve, A3
Böszörményi, Z2
Langelier, P1
Bédard, P2
Parent, A1
Roberge, AG1
Birkmayer, W1
Curzon, G1
Jurna, I4
Lanzer, G1
Müller-Calgan, H1
Sommer, S1
Theres, C1
Bachmann, T1
Hartmann-von Monakow, K1
Constantinidis, J1
Ungerstedt, U1
Chase, TN1
Divac, I1
Ditfurth, HV1
Aceto, MD1
Harris, LS1
Lesher, GY1
Pearl, J1
Brown, TG1
Turunen, S1
Achté, KA1
Sourkes, TL1
Gordon, N1
Bordeleau, JM1
Tétreault, L1
Crane, GE2
Wolf, SM1
Duvoisin, RC3
Tarsy, D1
Millichap, JG1
Fowler, GW1
Mones, RJ1
Peters, HA1
Daly, RF1
Sato, S2
Degkwitz, R1
North, RR1
Boggan, WO1
Seiden, LS1
Daly, R1
Peters, H1
Christie, JE1
Crow, TJ1
Ericsson, AD2
Wertman, BG2
Duffy, KM1
Himwich, WA2
Goldstein, SL1
Fox, MW1
Rovine, BW1
Goldstein, S1
Leiner, K1
Stout, M1
Kato, T1
Yoshioka, T1
Tauchi, K1
Deschambault, M1
Lachance, R1
Radouco-Thomas, S1
Galambos, E2
Pfeifer, AK2
György, L1
Molnár, J1
Ostrovskaia, RU1
Dill, RE1
Nickey, WM1
Little, MD1
Blazsó, S1
Michaelis, R1

Reviews

10 reviews available for reserpine and Movement Disorders

ArticleYear
Tetrabenazine, a monoamine-depleting drug used in the treatment of hyperkinetic movement disorders.
    The American journal of geriatric pharmacotherapy, 2010, Volume: 8, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Cytochrome P

2010
[COMPLICATIONS DURING CLINICAL THERAPY WITH PSYCHOPHARMACA].
    Arztliche Forschung, 1964, Jan-10, Volume: 18

    Topics: Agranulocytosis; Autonomic Nervous System Diseases; Chemical and Drug Induced Liver Injury; Chlorpro

1964
Effects of chronic administration of neuroleptics: dyskinesias in monkeys.
    Pharmacology & therapeutics. Part B: General & systematic pharmacology, 1976, Volume: 2, Issue:1

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Butyrophenones; Depression, Chemical; Drug Toleranc

1976
Drug-induced parkinsonism and other movement disorders.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1990, Volume: 17, Issue:2

    Topics: Haloperidol; Humans; Movement Disorders; MPTP Poisoning; Parkinson Disease, Secondary; Phenothiazine

1990
The biochemistry of dyskinesias.
    International review of neurobiology, 1967, Volume: 10

    Topics: Acetylcholine; Animals; Catecholamines; Cats; Copper; Dihydroxyphenylalanine; Dogs; Hepatolenticular

1967
Pathological aspects on Parkinson's syndrome.
    Acta neurologica Scandinavica. Supplementum, 1972, Volume: 51

    Topics: Animals; Basal Ganglia; Basal Ganglia Diseases; Central Nervous System; Chlorpromazine; Corpus Stria

1972
Drug-induced extrapyramidal disorders.
    Research publications - Association for Research in Nervous and Mental Disease, 1972, Volume: 50

    Topics: Antiparkinson Agents; Apomorphine; Basal Ganglia Diseases; Benztropine; Dihydroxyphenylalanine; Dopa

1972
Persistent dyskinesia.
    The British journal of psychiatry : the journal of mental science, 1973, Volume: 122, Issue:569

    Topics: Age Factors; Brain Damage, Chronic; Central Nervous System Diseases; Dopamine; Female; Humans; Male;

1973
Treatment of "minimal brain dysfunction" syndromes. Selection of drugs for children with hyperactivity and learning disabilities.
    Pediatric clinics of North America, 1967, Volume: 14, Issue:4

    Topics: Amphetamine; Anticonvulsants; Brain Damage, Chronic; Child; Chlordiazepoxide; Chlorpromazine; Clinic

1967
Parkinson's disease. II.
    New York state journal of medicine, 1970, Nov-15, Volume: 70, Issue:22

    Topics: Basal Ganglia; Catecholamines; Dihydroxyphenylalanine; Gait; Humans; Mental Processes; Movement Diso

1970

Trials

3 trials available for reserpine and Movement Disorders

ArticleYear
Treatment of drug-induced dyskinesias.
    Lancet (London, England), 1970, Feb-14, Volume: 1, Issue:7642

    Topics: Aged; Dihydroxyphenylalanine; Humans; Methyldopa; Middle Aged; Movement Disorders; Parkinson Disease

1970
[Extrapyramidal symptoms during the use of neuroleptics].
    Der Nervenarzt, 1967, Volume: 38, Issue:4

    Topics: Butyrophenones; Central Nervous System Stimulants; Clinical Trials as Topic; Extrapyramidal Tracts;

1967
Treatment of "minimal brain dysfunction" syndromes. Selection of drugs for children with hyperactivity and learning disabilities.
    Pediatric clinics of North America, 1967, Volume: 14, Issue:4

    Topics: Amphetamine; Anticonvulsants; Brain Damage, Chronic; Child; Chlordiazepoxide; Chlorpromazine; Clinic

1967

Other Studies

83 other studies available for reserpine and Movement Disorders

ArticleYear
Effect of Hypericum perforatum on different models of movement disorders in rats.
    Behavioural pharmacology, 2013, Volume: 24, Issue:7

    Topics: Animals; Disease Models, Animal; Fluphenazine; Hypericum; Male; Mastication; Motor Activity; Movemen

2013
(-) Epigallocatechin-3-gallate attenuates reserpine-induced orofacial dyskinesia and oxidative stress in rat striatum.
    Pharmacology, biochemistry, and behavior, 2015, Volume: 131

    Topics: Animals; Catalase; Catechin; Corpus Striatum; Disease Models, Animal; Glutathione; Lipid Peroxidatio

2015
Magnesium Supplementation Prevents and Reverses Experimentally Induced Movement Disturbances in Rats: Biochemical and Behavioral Parameters.
    Biological trace element research, 2015, Volume: 166, Issue:2

    Topics: Animals; Brain; Disease Models, Animal; Erythrocytes; Lipid Peroxidation; Magnesium; Male; Movement

2015
Physical exercise improves motor and short-term social memory deficits in reserpinized rats.
    Brain research bulletin, 2009, Aug-14, Volume: 79, Issue:6

    Topics: Analysis of Variance; Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Male

2009
Effect of Hibiscus rosa sinensis on reserpine-induced neurobehavioral and biochemical alterations in rats.
    Indian journal of experimental biology, 2009, Volume: 47, Issue:7

    Topics: Animals; Antioxidants; Behavior, Animal; Brain; Disease Models, Animal; Dyskinesia, Drug-Induced; Hi

2009
Short term dietary fish oil supplementation improves motor deficiencies related to reserpine-induced parkinsonism in rats.
    Lipids, 2011, Volume: 46, Issue:2

    Topics: Animals; Catalepsy; Dietary Supplements; Disease Models, Animal; Fish Oils; Male; Movement Disorders

2011
Comparative study between two animal models of extrapyramidal movement disorders: prevention and reversion by pecan nut shell aqueous extract.
    Behavioural brain research, 2011, Aug-01, Volume: 221, Issue:1

    Topics: Animals; Basal Ganglia Diseases; Carya; Catalepsy; Disease Models, Animal; Haloperidol; Male; Moveme

2011
Ethanolic extract of Rubia peregrina L. (Rubiaceae) inhibits haloperidol-induced catalepsy and reserpine-induced orofacial dyskinesia.
    Natural product research, 2012, Volume: 26, Issue:5

    Topics: Animals; Catalepsy; Ethanol; Haloperidol; Male; Movement Disorders; Plant Extracts; Rats; Reserpine;

2012
[Systematic neuroleptic therapy with the appearance of parkinsonian states].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Antipsychotic Agents; Chlorpromazine; Humans; Movement Disorders; Reserpine

1956
[Systematic neuroleptic therapy with the appearance of parkinsonian states].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Antipsychotic Agents; Chlorpromazine; Humans; Movement Disorders; Reserpine

1956
[Systematic neuroleptic therapy with the appearance of parkinsonian states].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Antipsychotic Agents; Chlorpromazine; Humans; Movement Disorders; Reserpine

1956
[Systematic neuroleptic therapy with the appearance of parkinsonian states].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Antipsychotic Agents; Chlorpromazine; Humans; Movement Disorders; Reserpine

1956
[Extrapyramidal movement disorders during chlorpromazine and reserpine therapy; clinical and electromyographic studies].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Movement Disorders;

1956
[Extrapyramidal movement disorders during chlorpromazine and reserpine therapy; clinical and electromyographic studies].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Movement Disorders;

1956
[Extrapyramidal movement disorders during chlorpromazine and reserpine therapy; clinical and electromyographic studies].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Movement Disorders;

1956
[Extrapyramidal movement disorders during chlorpromazine and reserpine therapy; clinical and electromyographic studies].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Movement Disorders;

1956
[Serpasil treatment of extrapyramidal hyperkinesia].
    Wiener klinische Wochenschrift, 1956, Aug-17, Volume: 68, Issue:33

    Topics: Humans; Hyperkinesis; Movement Disorders; Reserpine

1956
[Serpasil treatment of extrapyramidal hyperkinesia].
    Wiener klinische Wochenschrift, 1956, Aug-17, Volume: 68, Issue:33

    Topics: Humans; Hyperkinesis; Movement Disorders; Reserpine

1956
[Serpasil treatment of extrapyramidal hyperkinesia].
    Wiener klinische Wochenschrift, 1956, Aug-17, Volume: 68, Issue:33

    Topics: Humans; Hyperkinesis; Movement Disorders; Reserpine

1956
[Serpasil treatment of extrapyramidal hyperkinesia].
    Wiener klinische Wochenschrift, 1956, Aug-17, Volume: 68, Issue:33

    Topics: Humans; Hyperkinesis; Movement Disorders; Reserpine

1956
Effects of reserpine in animals, especially primates.
    Transactions of the American Neurological Association, 1956, Issue:81st Meeti

    Topics: Animals; Catalepsy; Movement Disorders; Primates; Reserpine

1956
[Reserpine treatment of certain forms of hyperkinesia in children; report on 20 cases].
    Minerva pediatrica, 1957, Sep-22, Volume: 9, Issue:38

    Topics: Child; Humans; Hyperkinesis; Infant; Movement Disorders; Reserpine

1957
[Experiences with reserpine in the treatment of agitated & overactive children & adolescents].
    Der Nervenarzt, 1958, Jun-20, Volume: 29, Issue:6

    Topics: Child; Humans; Infant; Movement Disorders; Psychology, Child; Psychomotor Agitation; Reserpine

1958
[Therapeutic value of extra-pyramidal symptoms in chlorpromazine & reserpine therapy].
    L'Encephale, 1958, Volume: 47, Issue:6

    Topics: Chlorpromazine; Extrapyramidal Tracts; Handwriting; Humans; Movement Disorders; Reserpine

1958
HYPERMOTILITY EVOKED BY LESIONS OF THE SEPTUM AND ANTERIOR HYPOTHALAMUS.
    Acta physiologica Academiae Scientiarum Hungaricae, 1963, Volume: 23

    Topics: Aminopyrine; Amygdala; Atropine; Body Temperature; Caudate Nucleus; Cerebral Ventricles; Chlorpromaz

1963
EFFECT OF ALPHA-METHYL DOPA AND RESERPINE IN HUNTINGTON'S CHOREA, PARKINSON'S DISEASE AND OTHER MOVEMENT DISORDERS.
    Life sciences (1962), 1963, Volume: 9

    Topics: Adolescent; Chorea; Dystonia Musculorum Deformans; Dystonic Disorders; Genetic Diseases, X-Linked; H

1963
[ON THE TREATMENT OF EXTRAPYRAMIDAL HYPERKINESIA WITH A NEW RESERPINE DERIVATIVE (RESEPINE ASCORBINATE)].
    Wiener klinische Wochenschrift, 1963, Oct-04, Volume: 75

    Topics: Ascorbic Acid; Athetosis; Chorea; Encephalitis; Extrapyramidal Tracts; Humans; Hyperkinesis; Movemen

1963
THE EFFECT OF L-3, 4-DIHYDROXYPHENYLALANINE AND DL-5-HYDROXYTRYPTOPHAN ON RIGIDITY AND TREMOR INDUCED BY RESERPINE, CHLORPROMAZINE AND PHENOXYBENZAMINE.
    Life sciences (1962), 1964, Volume: 3

    Topics: 5-Hydroxytryptophan; Amino Acids; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Inulin; Movement

1964
[ON THE ANTAGONISM OF THE ACTION OF NEUROLEPTICS AND ANTIPARKINSON AGENTS].
    Der Nervenarzt, 1964, Volume: 35

    Topics: Antiparkinson Agents; Antipsychotic Agents; Chlorpromazine; Handwriting; Humans; Movement Disorders;

1964
AN APPARENTLY IRREVERSIBLE SYNDROME OF ABNORMAL MOVEMENTS FOLLOWING PHENOTHIAZINE MEDICATION.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Brain; Brain Damage, Chronic; Brain Diseases; Chlorpromazine; Chorea; Diagnosis, Differential; Elect

1964
URINARY METABOLITES OF SOME MONOAMINES AND CLINICAL EFFECTS UNDER RESERPINE AND CHLORPROMAZINE.
    The British journal of psychiatry : the journal of mental science, 1965, Volume: 111

    Topics: Autonomic Nervous System Diseases; Chlorpromazine; Drug Therapy; Extrapyramidal Tracts; Fluids and S

1965
D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Feb-23, Volume: 25, Issue:8

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiparkinson Agents; Antipsych

2005
Stereotype hyperactive behaviour produced by dopamine in the absence of noradrenaline.
    Life sciences, 1967, Jul-01, Volume: 6, Issue:13

    Topics: Animals; Behavior, Animal; Brain Chemistry; Carbamates; Catecholamines; Dihydroxyphenylalanine; Dopa

1967
The 5HT(1B) receptor agonist, CP-93129, inhibits [(3)H]-GABA release from rat globus pallidus slices and reverses akinesia following intrapallidal injection in the reserpine-treated rat.
    British journal of pharmacology, 2000, Volume: 130, Issue:8

    Topics: Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Globus Pallidus; In Vitro Techni

2000
Rapid-eye-movement sleep in jittery infants.
    Early human development, 2002, Volume: 66, Issue:1

    Topics: Female; Haloperidol; Humans; Infant; Male; Maternal-Fetal Exchange; Methyldopa; Movement Disorders;

2002
Acute dystonia as an idiosyncratic response to neuroleptics in baboons.
    Brain : a journal of neurology, 1977, Volume: 100, Issue:2

    Topics: 5-Hydroxytryptophan; Acute Disease; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; H

1977
Therapeutic response in hemiballismus.
    Annals of neurology, 1979, Volume: 6, Issue:2

    Topics: Aged; Female; Haloperidol; Humans; Movement Disorders; Remission, Spontaneous; Reserpine

1979
Neurochemical and neuropharmacological investigations with four ergot derivatives: bromocriptine, dihydroergotoxine, CF 25-397 and CM 29-712.
    Pharmacology, 1978, Volume: 16 Suppl 1

    Topics: Animals; Behavior, Animal; Brain; Bromocriptine; Catecholamines; Chemical Phenomena; Chemistry; Dihy

1978
Treatment with hemiballism with reserpine.
    Annals of neurology, 1978, Volume: 4, Issue:6

    Topics: Humans; Male; Middle Aged; Movement Disorders; Reserpine

1978
Stereotaxic lesions and movement disorders in monkeys.
    Advances in neurology, 1975, Volume: 10

    Topics: Animals; Brain; Brain Mapping; Butyrophenones; Catalepsy; Catatonia; Cerebellum; Chorea; Haplorhini;

1975
Proceedings: The mechanism of the effect of dopamine-beta-hydroxylase inhibitor FLA-63 on the L-DOPA reversal of reserpine akinesia.
    British journal of pharmacology, 1975, Volume: 54, Issue:2

    Topics: Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Dopamine beta-Hydroxylase; Imidazoles

1975
Apomorphine and piribedil in rats: biochemical and pharmacologic studies.
    Advances in neurology, 1975, Volume: 9

    Topics: Amygdala; Animals; Apomorphine; Behavior; Brain; Corpus Striatum; Drug Synergism; Hippocampus; Human

1975
Neuroleptics and the corpus striatum: clinical implications.
    Diseases of the nervous system, 1976, Volume: 37, Issue:4

    Topics: Acetylcholine; Basal Ganglia Diseases; Benztropine; Corpus Striatum; Dopamine; Fluphenazine; Haloper

1976
Tardive dyskinesia.
    American journal of hospital pharmacy, 1976, Volume: 33, Issue:5

    Topics: Choline; Deanol; Dopamine Antagonists; Haloperidol; Humans; Methyldopa; Movement Disorders; Papaveri

1976
Akinesia due to catecholamine depletion in mice is prevented by caffeine. Further evidence for an involvement of adenosinergic system in the control of motility.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:4

    Topics: Adenosine; alpha-Methyltyrosine; Animals; Caffeine; Catecholamines; Dose-Response Relationship, Drug

1991
L-dopa esters as potential prodrugs: behavioural activity in experimental models of Parkinson's disease.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:8

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Female; Hydroxydopamines; Levodopa; Male; Mice; M

1987
Chronic beta-adrenergic stimulation increases in mice the sensitivity to methysergide and the number of cerebral high affinity serotonin binding sites (5-HT-1).
    Journal of neural transmission, 1986, Volume: 67, Issue:3-4

    Topics: Animals; Binding Sites; Brain; Clenbuterol; Drug Synergism; Ethanolamines; Male; Methysergide; Mice;

1986
Pharmacological characteristics of tremor, rigidity and hypokinesia induced by reserpine in rat.
    Neuropharmacology, 1987, Volume: 26, Issue:9

    Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Female; Haloperidol; Levodop

1987
Toxicity and neuropharmacology of cyclopiazonic acid.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1985, Volume: 23, Issue:9

    Topics: Animals; Body Weight; Chlorpromazine; Electrocardiography; Electroencephalography; Heart Rate; Hexob

1985
Dopaminergic and cholinergic mechanisms in relation to postural tremor in the monkey and circling movements in the cat.
    Advances in neurology, 1974, Volume: 5

    Topics: Acetylcholine; Amphetamine; Animals; Cats; Corpus Striatum; Disease Models, Animal; Dopamine; Fronta

1974
Alpha-rigidity in reserpinized rats.
    Experientia, 1964, Feb-15, Volume: 20, Issue:2

    Topics: Animals; Dihydroxyphenylalanine; Electromyography; Electrophysiology; Movement Disorders; Muscle Spi

1964
[Experimental findings and new aspects in extrapyramidal diseases].
    Wiener Zeitschrift fur Nervenheilkunde und deren Grenzgebiete, 1966, Volume: 23, Issue:1

    Topics: 5-Hydroxytryptophan; Blood Pressure; Body Temperature Regulation; Chorea; Dihydroxyphenylalanine; Do

1966
Reserpine rigidity in the rat--a model for the analysis of antiparkinson drugs.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 259, Issue:2

    Topics: 1-Propanol; Animals; Biperiden; Cerebral Decortication; Electromyography; Methamphetamine; Models, N

1968
Depression by antiparkinson drugs of reserpine rigidity.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, May-07, Volume: 260, Issue:1

    Topics: 1-Propanol; Animals; Biperiden; Cyclohexanes; Depression, Chemical; Electromyography; Methamphetamin

1968
Inhibition of the effect of reserpine on motor control by drugs which influence reserpine rigidity.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1969, Volume: 262, Issue:3

    Topics: 1-Propanol; Animals; Atropine; Biperiden; Cyclohexanes; Cyclopentanes; Depression, Chemical; Dihydro

1969
[Reserpine-parkinsonoid syndrome in the chimpanzee and its treatment with fencamfamin].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2

    Topics: Animals; Antidepressive Agents; Catatonia; Hominidae; Humans; Movement Disorders; Parkinson Disease;

1968
The effect of physostigmine and tetrabenazine on spinal motor control and its inhibition by drugs which influence reserpine rigidity.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1969, Volume: 263, Issue:3

    Topics: 1-Propanol; Animals; Atropine; Biperiden; Dihydroxyphenylalanine; Electric Stimulation; Electromyogr

1969
[Specific therapy of extrapyramidal-motor syndromes].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Analgesics; Athetosis; Chorea; Datura stramonium; Dihydroxyphenylalanine; Dystonia Musculorum Deform

1969
[Monoamines and choreic syndromes].
    Revue neurologique, 1972, Volume: 127, Issue:1

    Topics: Amines; Butyrophenones; Chorea; Diazepam; Dihydroxyphenylalanine; Dopamine; Ganglia; Globus Pallidus

1972
Drug treatment of diseases characterized by abnormal movements.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:9

    Topics: Chorea; Diazepam; Ethanol; Haloperidol; Humans; Huntington Disease; Levodopa; Movement Disorders; My

1973
Striatal dopamine release after amphetamine or nerve degeneration revealed by rotational behaviour.
    Acta physiologica Scandinavica. Supplementum, 1971, Volume: 367

    Topics: Amphetamine; Animals; Apomorphine; Brain; Butyrophenones; Dopamine; Electrocoagulation; Haloperidol;

1971
Drug-induced syndromes in rats with large, chronic lesions in the corpus striatum.
    Psychopharmacologia, 1972, Volume: 27, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Basal Ganglia; Behavior, Animal; Brain; Globus Pallidus; Haloperi

1972
Pharmacologic studies with 7-benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:2

    Topics: Amphetamine; Animals; Catecholamines; Chlorine; Depression; Drug Antagonism; Drug Synergism; Humans;

1967
The bucco-linguo-masticatory syndrome as a side-effect of neuroleptics therapy.
    The Psychiatric quarterly, 1967, Volume: 41, Issue:2

    Topics: Adult; Aged; Brain Damage, Chronic; Cheek; Chlorpromazine; Chlorprothixene; Clopenthixol; Female; Ha

1967
Correlative neuroanatomical and neuropharmacological study of tremor and catatonia in the monkey.
    Neuropharmacology, 1971, Volume: 10, Issue:3

    Topics: Animals; Catatonia; Cerebellum; Cerebral Cortex; Dihydroxyphenylalanine; Dopamine; Haplorhini; Human

1971
Drugs and motor functions.
    Developmental medicine and child neurology, 1971, Volume: 13, Issue:3

    Topics: Athetosis; Catecholamines; Cholinesterase Inhibitors; Chorea; Dihydroxyphenylalanine; Dopamine; Extr

1971
[Study of extrapyramidal manifestations induced by neuroleptics].
    Revue canadienne de biologie, 1972, Volume: 31

    Topics: Antiparkinson Agents; Chlorpromazine; Drug Synergism; Extrapyramidal Tracts; Fluphenazine; Haloperid

1972
Mediocre effects of reserpine on tardive dyskinesia.
    The New England journal of medicine, 1973, Jan-11, Volume: 288, Issue:2

    Topics: Adult; Female; Humans; Middle Aged; Movement Disorders; Reserpine

1973
Reserpine: cause and treatment of oral-facial dyskinesia.
    Bulletin of the Los Angeles neurological societies, 1973, Volume: 38, Issue:2

    Topics: Deglutition Disorders; Diazepam; Face; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged

1973
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi.
    Brain research, 1974, May-10, Volume: 71, Issue:1

    Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose

1974
Role of noradrenaline in levodopa reversal of reserpine akinesia.
    Brain research, 1974, Sep-13, Volume: 77, Issue:3

    Topics: Animals; Chlorpromazine; Dihydroxyphenylalanine; Haloperidol; Mice; Movement Disorders; Norepinephri

1974
Reserpine for tardive dyskinesia.
    The New England journal of medicine, 1972, Jan-13, Volume: 286, Issue:2

    Topics: Humans; Movement Disorders; Phytotherapy; Plants, Medicinal; Rauwolfia; Reserpine

1972
[Drug-induced Parkinson's syndrome].
    Deutsche medizinische Wochenschrift (1946), 1972, Jun-02, Volume: 97, Issue:22

    Topics: Acetylcholinesterase; Antiparkinson Agents; Dihydroxyphenylalanine; Dopamine; Humans; Movement Disor

1972
The rabbit syndrome. A peculiar extrapyramidal reaction.
    Canadian Psychiatric Association journal, 1972, Volume: 17, Issue:2

    Topics: Aged; Anxiety; Basal Ganglia Diseases; Benztropine; Chlorpromazine; Fatigue; Female; Humans; Male; M

1972
Reserpine for tardive dyskinesia.
    The New England journal of medicine, 1972, Mar-16, Volume: 286, Issue:11

    Topics: Humans; Movement Disorders; Reserpine

1972
Drug-induced movement disorders.
    Postgraduate medicine, 1971, Volume: 50, Issue:3

    Topics: Amphetamine; Contraceptives, Oral; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Female; Hu

1971
Dopa reversal of reserpine enhancement of audiogenic seizure susceptibility in mice.
    Physiology & behavior, 1971, Volume: 6, Issue:3

    Topics: Animals; Behavior, Animal; Benzyl Compounds; Brain Chemistry; Dihydroxyphenylalanine; Dopa Decarboxy

1971
Reserpine therapy of phenothiazine induced dyskinesia.
    Diseases of the nervous system, 1971, Volume: 32, Issue:10

    Topics: Adjustment Disorders; Aged; Female; Humans; Hypotension, Orthostatic; Male; Movement Disorders; Phen

1971
Turning behaviour as an index of the action of amphetamines and ephedrines on central dopamine-containing neurones.
    British journal of pharmacology, 1971, Volume: 43, Issue:3

    Topics: Amphetamine; Animals; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dopamine; Ephedrine; Explo

1971
Reversal of the reserpine syndrome with L-dopa metabolites in reserpinized rats.
    Neurology, 1971, Volume: 21, Issue:10

    Topics: Animals; Central Nervous System; Dihydroxyphenylalanine; Motor Skills; Movement Disorders; Normetane

1971
Sensitivity studies of L-dopa metabolites in reserpinized rats and their clinical significance.
    Neurology, 1971, Volume: 21, Issue:11

    Topics: Animals; Brain; Catechols; Dihydroxyphenylalanine; Female; Humans; Male; Mandelic Acids; Middle Aged

1971
Psychoactive agents in dogs with bilateral lesions in subcortical structures.
    Neurology, 1968, Volume: 18, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Caudate Nucleus; Dogs; Movement Disorders; Quinoline

1968
Psychoactive agents in dogs with bilateral lesions in subcortical structures.
    Neurology, 1971, Volume: 21, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Caudate Nucleus; Chlorpromazine; Dogs; Dopamine; Haloperidol; Hippocam

1971
[Therapeutic findings in hemiballism and hemichorea].
    Saishin igaku. Modern medicine, 1969, Volume: 24, Issue:11

    Topics: Adolescent; Aged; Chorea; Electroencephalography; Female; Humans; Movement Disorders; Reserpine

1969
[Attempt at treatment of permanent type of post-neuroleptic dyskinesia].
    Laval medical, 1970, Volume: 41, Issue:7

    Topics: Aged; Female; Humans; Male; Methyldopa; Middle Aged; Movement Disorders; Reserpine; Tranquilizing Ag

1970
[Extrapyramidal syndrome in animal experiments: rôle of calcium and o-methylated derivatives].
    Laval medical, 1970, Volume: 41, Issue:7

    Topics: Animals; Calcium; Calcium Metabolism Disorders; Depression, Chemical; Dihydroxyphenylalanine; Dopami

1970
Study on the excitation induced by amphetamine, cocaine and alpha-methyltryptamine.
    Psychopharmacologia, 1967, Volume: 11, Issue:2

    Topics: Amphetamine; Animals; Atropine; Benactyzine; Central Nervous System; Chlorpromazine; Cocaine; Mice;

1967
Toxicity and the action of reserpine on brain monoamines after pretreatment with monoamine oxidase inhibitors in isolated and aggregated mice.
    Psychopharmacologia, 1967, Volume: 11, Issue:2

    Topics: Animals; Brain; Crowding; Dopamine; Fever; Mice; Movement Disorders; Nialamide; Norepinephrine; Parg

1967
[The basic pharmacologic properties of several 2-substituted tryptamines].
    Biulleten' eksperimental'noi biologii i meditsiny, 1967, Volume: 63, Issue:3

    Topics: Animals; Brain; Cerebral Cortex; Electroencephalography; Mice; Movement Disorders; Rabbits; Rats; Re

1967
Dyskinesia in rats following chemical stimulation of the neostriatum.
    Texas reports on biology and medicine, 1968,Spring, Volume: 26, Issue:1

    Topics: Animals; Carbachol; Dopamine; Extrapyramidal Tracts; Male; Motor Activity; Movement Disorders; Norep

1968
[On the pharmacotherapeutic treatment of cerebral palsy. I. Treatment of movement disorders].
    Monatsschrift fur Kinderheilkunde, 1965, Volume: 113, Issue:9

    Topics: Cerebral Palsy; Child; Child, Preschool; Chlorpromazine; Humans; Infant; Infant, Newborn; Mephenesin

1965
[Tetany, hysterical attack or side-effect of therapy?].
    Medizinische Klinik, 1966, Mar-25, Volume: 61, Issue:12

    Topics: Adolescent; Adult; Female; Humans; Movement Disorders; Reserpine; Tetany; Tranquilizing Agents; Trif

1966