reserpine has been researched along with Morphine Abuse in 14 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It was found that pimozide, haloperidol and alpha-methyl-p-tyrosine (alpha-MT), drugs inhibiting central catecholaminergic (CA) transmission, increased the development of morphine dependence measured as wet dog shakes in rats." | 7.66 | The influence of pimozide, haloperidol, alpha-methyl-p-tyrosine and reserpine on the development of morphine dependence in rats. ( Kruszewska, A; Langwiński, R, 1983) |
| "It was found that pimozide, haloperidol and alpha-methyl-p-tyrosine (alpha-MT), drugs inhibiting central catecholaminergic (CA) transmission, increased the development of morphine dependence measured as wet dog shakes in rats." | 3.66 | The influence of pimozide, haloperidol, alpha-methyl-p-tyrosine and reserpine on the development of morphine dependence in rats. ( Kruszewska, A; Langwiński, R, 1983) |
| "Reserpine (Res) was used to deplete central noradrenaline." | 1.29 | Influences of locus coeruleus lesions and reserpine treatment on opioid physical dependence in rats. ( Miao, H; Qin, BY, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MAGGIOLO, C | 1 |
| HUIDOBRO, F | 1 |
| Martin, WR | 1 |
| Eades, CG | 1 |
| Kruszewska, A | 2 |
| Langwiński, R | 2 |
| Miao, H | 1 |
| Qin, BY | 1 |
| Gibson, A | 1 |
| Pollock, D | 2 |
| Koyuncuoglu, H | 1 |
| Güngör, M | 1 |
| Parmar, NS | 1 |
| Tariq, M | 1 |
| Ageel, AM | 1 |
| Flórez, J | 1 |
| Delgado, G | 1 |
| Armijo, JA | 1 |
| Kamei, C | 1 |
| Shimomura, K | 1 |
| Ueki, S | 1 |
| Ayhan, IH | 1 |
| Randrup, A | 1 |
| Muir, TC | 1 |
| MacDonald, A | 1 |
| Henderson, G | 1 |
| Iwamoto, ET | 1 |
| Ho, IK | 1 |
| Way, EL | 1 |
| Hasse, HE | 1 |
| Schiefgen, W | 1 |
| Schönhöfer, P | 1 |
14 other studies available for reserpine and Morphine Abuse
| Article | Year |
|---|---|
The influence of some drugs on the abstinence syndrome to morphine in mice.
Topics: Animals; Cortisone; Hypnotics and Sedatives; Mice; Monoamine Oxidase Inhibitors; Morphine; Morphine | 1962 |
Pharmacological studies of spinal cord adrenergic and cholinergic mechanisms and their relation to physical dependence on morphine.
Topics: Amphetamine; Animals; Atropine; Dextroamphetamine; Dogs; Electric Stimulation; Humans; Methoxamine; | 1967 |
The influence of pimozide, haloperidol, alpha-methyl-p-tyrosine and reserpine on the development of morphine dependence in rats.
Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Catecholamines; Haloperidol; Humans; Male; Methy | 1983 |
Influences of locus coeruleus lesions and reserpine treatment on opioid physical dependence in rats.
Topics: Animals; Body Weight; Etorphine; Female; Locus Coeruleus; Male; Morphine Dependence; Neurons; Opioid | 1995 |
[The effect of reserpine on the morphine abstinence syndrome in mice (author's transl)].
Topics: 5-Hydroxytryptophan; Animals; Drug Antagonism; Humans; Levodopa; Male; Mice; Morphine Dependence; Re | 1979 |
The involvement of corticosteroids in the supersensitivity produced in the rat anococcygeus muscle by morphine withdrawal, thyroidectomy or a single dose of reserpine.
Topics: Acetylcholine; Adrenalectomy; Animals; Body Weight; Corticosterone; Humans; In Vitro Techniques; Mal | 1975 |
Effect of nialamide and reserpine on brain free amino acids of rat dependent on and withdrawn from morphine.
Topics: Amino Acids; Animals; Body Weight; Brain; Brain Chemistry; Humans; Morphine Dependence; Nialamide; R | 1975 |
Studies on the gastroulcerogenic effects of pylorus ligation, hypothermic restraint stress, aspirin, indomethacin and reserpine in morphine dependent rats.
Topics: Animals; Aspirin; Gastric Acid; Hypothermia; Indomethacin; Ligation; Male; Morphine Dependence; Pylo | 1987 |
Brain amines and development of acute tolerance to and dependence on morphine in the respiratory center of decerebrate cats.
Topics: Amines; Animals; Blood Pressure; Carbon Dioxide; Cats; Decerebrate State; Drug Tolerance; Fenclonine | 1973 |
Significance of withdrawal jumping response in predicting physical dependence in mice.
Topics: Amitriptyline; Animals; Atropine; Cannabis; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Imip | 1973 |
Role of brain noradrenaline in morphine-induced stereotyped behaviour.
Topics: Acetamides; Amphetamine; Animals; Antihypertensive Agents; Behavior, Animal; Brain; Butyrophenones; | 1972 |
Morphine-induced changes in the sensitivity of the isolated colon and vas deferens of the rat.
Topics: Acetylcholine; Animals; Atropine; Colon; Dose-Response Relationship, Drug; Furans; Humans; In Vitro | 1972 |
Elevation of brain dopamine during naloxone-precipitated withdrawal in morphine-dependent mice and rats.
Topics: Animals; Atropine; Brain; Brain Stem; Cerebellum; Corpus Striatum; Dopamine; Humans; Hypothalamus; M | 1973 |
[Emergencies in drugged adolescents].
Topics: Adolescent; Amitriptyline; Benzazepines; Cannabis; Emergencies; Hallucinogens; Humans; Male; Morphin | 1972 |