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reserpine and MPTP Neurotoxicity Syndrome

reserpine has been researched along with MPTP Neurotoxicity Syndrome in 4 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Research Excerpts

ExcerptRelevanceReference
"This is a review of reserpine, haloperidol, and various phenothiazines that produce parkinsonism and other movement disorders."4.78Drug-induced parkinsonism and other movement disorders. ( Ross, RT, 1990)
"Ropinirole was weakly neuroprotective in this model."1.32S32504, a novel naphtoxazine agonist at dopamine D3/D2 receptors: II. Actions in rodent, primate, and cellular models of antiparkinsonian activity in comparison to ropinirole. ( Brocco, M; Brotchie, J; Crossman, A; Di Cara, B; Gobert, A; Hill, M; Jackson, M; Jenner, P; Joyce, JN; McGuire, S; Millan, MJ; Peglion, JL; Smith, L, 2004)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ouattara, B1
Gasparini, F1
Morissette, M1
Grégoire, L1
Samadi, P1
Gomez-Mancilla, B1
Di Paolo, T1
Schlüter, OM1
Fornai, F1
Alessandrí, MG1
Takamori, S1
Geppert, M1
Jahn, R1
Südhof, TC1
Millan, MJ1
Di Cara, B1
Hill, M1
Jackson, M1
Joyce, JN1
Brotchie, J1
McGuire, S1
Crossman, A1
Smith, L1
Jenner, P1
Gobert, A1
Peglion, JL1
Brocco, M1
Ross, RT1

Reviews

1 review available for reserpine and MPTP Neurotoxicity Syndrome

ArticleYear
Drug-induced parkinsonism and other movement disorders.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1990, Volume: 17, Issue:2

    Topics: Haloperidol; Humans; Movement Disorders; MPTP Poisoning; Parkinson Disease, Secondary; Phenothiazine

1990

Other Studies

3 other studies available for reserpine and MPTP Neurotoxicity Syndrome

ArticleYear
Effect of L-Dopa on metabotropic glutamate receptor 5 in the brain of parkinsonian monkeys.
    Journal of neurochemistry, 2010, Volume: 113, Issue:3

    Topics: Animals; Antiparkinson Agents; Autoradiography; Biogenic Amines; Brain Chemistry; Catecholamines; Ca

2010
Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice.
    Neuroscience, 2003, Volume: 118, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Uptake Inhibitors; alpha-Synuclein; Animals; Antibodies;

2003
S32504, a novel naphtoxazine agonist at dopamine D3/D2 receptors: II. Actions in rodent, primate, and cellular models of antiparkinsonian activity in comparison to ropinirole.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:3

    Topics: Acetylcholine; Animals; Callithrix; Cells, Cultured; Disease Models, Animal; Dopamine Agonists; Dopa

2004