reserpine has been researched along with Lupus Erythematosus, Systemic in 12 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Some of this information includes: the unexpected yet very real hazards as well as benefits associated with the long-term use of powerful drugs, in particular the original description of hydralazine-induced lupus, its relation to genetic markers and its association with control of hypertension; the apparently decreasing need for antihypertensive drugs in subjects with well-controlled severe and moderate hypertension; the identification of risk factors for the complications of hypertension and the quantitation of their effects; the decrease in the incidence of hypertensive complications associated with the pharmacologic treatment of severe, moderate and, at least, the upper ranges of mild hypertension; the possibility of designing a chemical to block a specific reaction and the realization that it would have broader than expected effects; and the primary prevention of myocardial infarction in very high risk subjects." | 4.77 | The evolution of antihypertensive therapy. ( Perry, HM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CIOBANU, V | 1 |
| VELICAN, D | 1 |
| SOILA, P | 1 |
| KALLIOMAEKI, JL | 1 |
| VIITANEN, SM | 1 |
| DEMARCO, P | 1 |
| SHOHOV, P | 1 |
| KRESKY, B | 1 |
| ZAINO, EC | 1 |
| SMITH, FG | 1 |
| LITMAN, N | 1 |
| LATTA, H | 1 |
| Blunt, RJ | 1 |
| Porter, JM | 2 |
| Lee, SL | 1 |
| CHase, PH | 1 |
| Rösch, J | 1 |
| Perry, HM | 1 |
| Golochevskaia, VS | 1 |
| Jasin, HE | 1 |
| Andreis, M | 1 |
| Cheatum, DE | 1 |
| Giuliano, V | 1 |
| Hurd, ER | 1 |
| Smiley, JD | 1 |
| Willerson, JT | 1 |
| Thompson, RH | 1 |
| Hookman, P | 1 |
| Herdt, J | 1 |
| Decker, JL | 1 |
5 reviews available for reserpine and Lupus Erythematosus, Systemic
| Article | Year |
|---|---|
Raynaud syndrome.
Topics: Adrenergic beta-Antagonists; Adult; Angiography; Antibodies, Antinuclear; Arterial Occlusive Disease | 1981 |
Drug-induced systemic lupus erythematosus: a critical review.
Topics: Adult; Allopurinol; Anti-Arrhythmia Agents; Anticonvulsants; Antithyroid Agents; Antitubercular Agen | 1975 |
The evolution of antihypertensive therapy.
Topics: Antihypertensive Agents; Bis-Trimethylammonium Compounds; Blood Pressure; Calcium Channel Blockers; | 1985 |
[Side effects of anti-arrhythmic agents].
Topics: 1-Propanol; Adrenal Cortex Hormones; Agranulocytosis; Anorexia Nervosa; Anti-Arrhythmia Agents; Anti | 1971 |
The 1972 annual meeting of the American Rheumatism Association.
Topics: Arthritis, Juvenile; Arthritis, Rheumatoid; Biopsy; Cartilage; Cathepsins; Complement System Protein | 1972 |
7 other studies available for reserpine and Lupus Erythematosus, Systemic
| Article | Year |
|---|---|
[Hydralazine syndrome after prolonged treatment with adelphan].
Topics: Hydralazine; Hydrazines; Hypertension; Lupus Erythematosus, Systemic; Reserpine | 1961 |
ANGIOGRAPHIC OBSERVATIONS ON THE EFFECT OF RESERPINE IN CONNECTIVE TISSUE DISEASES.
Topics: Angiography; Arthritis; Arthritis, Rheumatoid; Connective Tissue Diseases; Humans; Lupus Erythematos | 1963 |
DISSEMINATED LUPUS ERYTHEMATOSUS IN A 28-MONTH-OLD INFANT WITH ONSET DURING HYDRALAZINE THERAPY.
Topics: Blood Transfusion; Cerebral Palsy; Child; Diseases in Twins; Erythroblastosis, Fetal; Fetus; Hydrala | 1964 |
LUPUS GLOMERULONEPHRITIS. THE EFFECT OF LARGE DOSES OF CORTICOSTEROIDS ON RENAL FUNCTION AND RENAL LESIONS IN TWO CHILDREN.
Topics: Adolescent; Adrenal Cortex Hormones; Cortisone; Drug Therapy; Glomerulonephritis; Guanethidine; Hydr | 1965 |
Hand angiography and Raynaud's syndrome.
Topics: Adolescent; Adult; Aged; Angiography; Arthritis; Cold Temperature; Female; Hand; Humans; Lupus Eryth | 1977 |
When a drug is the culprit.
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Clofibrate; Depression; Drug-Related Side Effect | 1973 |
Reserpine in Raynaud's disease and phenomenon. Short-term response to intra-arterial injection.
Topics: Adolescent; Adult; Aged; Angiography; Body Temperature Regulation; Brachial Artery; Cold Temperature | 1970 |