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reserpine and Lupus Erythematosus, Systemic

reserpine has been researched along with Lupus Erythematosus, Systemic in 12 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Research Excerpts

ExcerptRelevanceReference
" Some of this information includes: the unexpected yet very real hazards as well as benefits associated with the long-term use of powerful drugs, in particular the original description of hydralazine-induced lupus, its relation to genetic markers and its association with control of hypertension; the apparently decreasing need for antihypertensive drugs in subjects with well-controlled severe and moderate hypertension; the identification of risk factors for the complications of hypertension and the quantitation of their effects; the decrease in the incidence of hypertensive complications associated with the pharmacologic treatment of severe, moderate and, at least, the upper ranges of mild hypertension; the possibility of designing a chemical to block a specific reaction and the realization that it would have broader than expected effects; and the primary prevention of myocardial infarction in very high risk subjects."4.77The evolution of antihypertensive therapy. ( Perry, HM, 1985)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199012 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
CIOBANU, V1
VELICAN, D1
SOILA, P1
KALLIOMAEKI, JL1
VIITANEN, SM1
DEMARCO, P1
SHOHOV, P1
KRESKY, B1
ZAINO, EC1
SMITH, FG1
LITMAN, N1
LATTA, H1
Blunt, RJ1
Porter, JM2
Lee, SL1
CHase, PH1
Rösch, J1
Perry, HM1
Golochevskaia, VS1
Jasin, HE1
Andreis, M1
Cheatum, DE1
Giuliano, V1
Hurd, ER1
Smiley, JD1
Willerson, JT1
Thompson, RH1
Hookman, P1
Herdt, J1
Decker, JL1

Reviews

5 reviews available for reserpine and Lupus Erythematosus, Systemic

ArticleYear
Raynaud syndrome.
    Seminars in arthritis and rheumatism, 1981, Volume: 10, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Angiography; Antibodies, Antinuclear; Arterial Occlusive Disease

1981
Drug-induced systemic lupus erythematosus: a critical review.
    Seminars in arthritis and rheumatism, 1975, Volume: 5, Issue:1

    Topics: Adult; Allopurinol; Anti-Arrhythmia Agents; Anticonvulsants; Antithyroid Agents; Antitubercular Agen

1975
The evolution of antihypertensive therapy.
    The American journal of cardiology, 1985, Dec-06, Volume: 56, Issue:16

    Topics: Antihypertensive Agents; Bis-Trimethylammonium Compounds; Blood Pressure; Calcium Channel Blockers;

1985
[Side effects of anti-arrhythmic agents].
    Klinicheskaia meditsina, 1971, Volume: 49, Issue:10

    Topics: 1-Propanol; Adrenal Cortex Hormones; Agranulocytosis; Anorexia Nervosa; Anti-Arrhythmia Agents; Anti

1971
The 1972 annual meeting of the American Rheumatism Association.
    Bulletin on the rheumatic diseases, 1972, Volume: 23, Issue:4

    Topics: Arthritis, Juvenile; Arthritis, Rheumatoid; Biopsy; Cartilage; Cathepsins; Complement System Protein

1972

Other Studies

7 other studies available for reserpine and Lupus Erythematosus, Systemic

ArticleYear
[Hydralazine syndrome after prolonged treatment with adelphan].
    Medicina interna, 1961, Volume: 13

    Topics: Hydralazine; Hydrazines; Hypertension; Lupus Erythematosus, Systemic; Reserpine

1961
ANGIOGRAPHIC OBSERVATIONS ON THE EFFECT OF RESERPINE IN CONNECTIVE TISSUE DISEASES.
    Archives of interamerican rheumatology : A.I.R, 1963, Volume: 6

    Topics: Angiography; Arthritis; Arthritis, Rheumatoid; Connective Tissue Diseases; Humans; Lupus Erythematos

1963
DISSEMINATED LUPUS ERYTHEMATOSUS IN A 28-MONTH-OLD INFANT WITH ONSET DURING HYDRALAZINE THERAPY.
    Clinical pediatrics, 1964, Volume: 3

    Topics: Blood Transfusion; Cerebral Palsy; Child; Diseases in Twins; Erythroblastosis, Fetal; Fetus; Hydrala

1964
LUPUS GLOMERULONEPHRITIS. THE EFFECT OF LARGE DOSES OF CORTICOSTEROIDS ON RENAL FUNCTION AND RENAL LESIONS IN TWO CHILDREN.
    American journal of diseases of children (1960), 1965, Volume: 110

    Topics: Adolescent; Adrenal Cortex Hormones; Cortisone; Drug Therapy; Glomerulonephritis; Guanethidine; Hydr

1965
Hand angiography and Raynaud's syndrome.
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1977, Volume: 127, Issue:1

    Topics: Adolescent; Adult; Aged; Angiography; Arthritis; Cold Temperature; Female; Hand; Humans; Lupus Eryth

1977
When a drug is the culprit.
    Geriatrics, 1973, Volume: 28, Issue:9

    Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Clofibrate; Depression; Drug-Related Side Effect

1973
Reserpine in Raynaud's disease and phenomenon. Short-term response to intra-arterial injection.
    Annals of internal medicine, 1970, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Aged; Angiography; Body Temperature Regulation; Brachial Artery; Cold Temperature

1970