reserpine has been researched along with Koch's Disease in 11 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bedaquiline (BDQ), an ATP synthase inhibitor, is the first drug to be approved for treatment of multi-drug resistant tuberculosis in decades." | 7.80 | Acquired resistance of Mycobacterium tuberculosis to bedaquiline. ( Andries, K; Coeck, N; de Jong, BC; Gevers, T; Koul, A; Lounis, N; Thys, K; Villellas, C; Vranckx, L, 2014) |
| "Pyrazinamide (PZA) is an important front-line anti-tuberculosis drug that is active only at acid pH." | 7.71 | Conditions that may affect the results of susceptibility testing of Mycobacterium tuberculosis to pyrazinamide. ( Permar, S; Sun, Z; Zhang, Y, 2002) |
| "Bedaquiline (BDQ), an ATP synthase inhibitor, is the first drug to be approved for treatment of multi-drug resistant tuberculosis in decades." | 3.80 | Acquired resistance of Mycobacterium tuberculosis to bedaquiline. ( Andries, K; Coeck, N; de Jong, BC; Gevers, T; Koul, A; Lounis, N; Thys, K; Villellas, C; Vranckx, L, 2014) |
| "Pyrazinamide (PZA) is an important front-line anti-tuberculosis drug that is active only at acid pH." | 3.71 | Conditions that may affect the results of susceptibility testing of Mycobacterium tuberculosis to pyrazinamide. ( Permar, S; Sun, Z; Zhang, Y, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andries, K | 1 |
| Villellas, C | 1 |
| Coeck, N | 1 |
| Thys, K | 1 |
| Gevers, T | 1 |
| Vranckx, L | 1 |
| Lounis, N | 1 |
| de Jong, BC | 1 |
| Koul, A | 1 |
| TESSIER, R | 1 |
| MARTRE, P | 1 |
| MAREE, C | 1 |
| BIESSY, R | 1 |
| LE TREUT, A | 1 |
| DAHAN, E | 1 |
| OLLAGNIER, C | 1 |
| PERRIN, LF | 1 |
| GARDERE, J | 1 |
| WALSH, JJ | 1 |
| HERRING, JL | 1 |
| LINN, RH | 1 |
| JACOBS, S | 1 |
| DERBES, V | 1 |
| CRISALLI, JP | 1 |
| RAMPINI, GF | 1 |
| LEVENDEL, L | 1 |
| LAKATOS, M | 1 |
| VARADY, T | 1 |
| KISS, L | 1 |
| LAPLACE, JM | 1 |
| BARRALES, MM | 1 |
| Zhang, Y | 1 |
| Permar, S | 1 |
| Sun, Z | 1 |
| Lee, SL | 1 |
| CHase, PH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacometrics to Advance Novel Regimens for Drug-resistant Tuberculosis[NCT03827811] | 625 participants (Anticipated) | Observational | 2020-01-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for reserpine and Koch's Disease
| Article | Year |
|---|---|
Drug-induced systemic lupus erythematosus: a critical review.
Topics: Adult; Allopurinol; Anti-Arrhythmia Agents; Anticonvulsants; Antithyroid Agents; Antitubercular Agen | 1975 |
10 other studies available for reserpine and Koch's Disease
| Article | Year |
|---|---|
Acquired resistance of Mycobacterium tuberculosis to bedaquiline.
Topics: Animals; Antitubercular Agents; Bacterial Proteins; Base Sequence; Clofazimine; Diarylquinolines; Dr | 2014 |
[Serpasil in phtisiology].
Topics: Antihypertensive Agents; Reserpine; Secologanin Tryptamine Alkaloids; Tuberculosis; Tuberculosis, Pu | 1956 |
[Temperature regulating action of Rauwolfia serpentina in pulmonary tuberculosis].
Topics: Humans; Rauwolfia; Reserpine; Temperature; Tuberculosis; Tuberculosis, Pulmonary | 1957 |
[Effects of reserpine on pulmonary arterial hypertension during tuberculosis; case report].
Topics: Humans; Hypertension; Hypertension, Pulmonary; Reserpine; Tuberculosis; Tuberculosis, Pulmonary | 1958 |
Measurements of the activity of ambulatory hospitalized tuberculous patients and the effects of a tranquilizing agent.
Topics: Exercise; Hypnotics and Sedatives; Reserpine; Tranquilizing Agents; Tuberculosis; Tuberculosis, Pulm | 1959 |
[Clinical studies of a new hypotensive drug in tuberculosis patients].
Topics: Antihypertensive Agents; Hypertension; Hypotension; Muscle Relaxants, Central; Reserpine; Theophylli | 1959 |
[The use of new tranquilizers (Frenolon, Melipramin, Hirepin) in the therapy of tuberculosis, with special reference to the alcoholic tuberculosis patients].
Topics: Chlorpropamide; Imipramine; Promethazine; Reserpine; Tranquilizing Agents; Tuberculosis; Tuberculosi | 1962 |
[Hirepin therapy of non-hypotonic tuberculous patients with complains in the sternal region].
Topics: Chlorpromazine; Reserpine; Thoracic Wall; Tuberculosis; Tuberculosis, Pulmonary | 1962 |
[Influence of the drug combination: reserpine-vitamin B12-vitamin B1 in the diet of tuberculous patients].
Topics: Corrinoids; Diet; Diet Therapy; Drug Combinations; Hematinics; Reserpine; Thiamine; Tuberculosis; Vi | 1962 |
Conditions that may affect the results of susceptibility testing of Mycobacterium tuberculosis to pyrazinamide.
Topics: Antitubercular Agents; Cell Survival; Colony Count, Microbial; Culture Media; Drug Interactions; Dru | 2002 |