reserpine has been researched along with Ischemic Attack, Transient in 19 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomized study was carried out to determine if the administration of reserpine and kanamycin to lower the concentration of vasoactive biogenic monoamines would reduce the incidence of cerebral vascular ischemic complications and death following the rupture of intracranial aneurysms." | 5.04 | Reduced incidence of cerebral ischemia following rupture of intracranial aneurysms. ( Bacon, V; Candia, G; Candia, M; Kido, D; Pessin, MS; Rosoff, CB; Zervas, NT, 1979) |
| "Patients suffering from a subarachnoid hemorrhage who were admitted to the Neurosurgical Unit of the Royal Perth Hospital during the period 1971 to 1979 were assessed with regard to the effectiveness of preoperative treatment with epsilon-aminocaproic acid, kanamycin, and reserpine." | 3.66 | Medical management of patients following a ruptured cerebral aneurysm, with epsilon-aminocaproic acid, kanamycin, and reserpine. ( Knuckey, NW; Stokes, BA, 1982) |
| "Pretreatment with reserpine was done as follows: 1 mg/kg of reserpine was injected subcutaneously once each day for 2 days." | 1.27 | [Experimental cerebral vasospasm induced by oxyhemoglobin and the sympathetic nervous system (Part 2): An investigation into denervation supersensitivity]. ( Endo, S; Iwai, R; Kamiyama, K; Otsuji, T; Sugita, T; Takaku, A, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (94.74) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Melli, A | 1 |
| Golinelli, G | 1 |
| Noseworthy, TW | 1 |
| Weir, B | 1 |
| Boisvert, D | 1 |
| Espinosa, F | 1 |
| Overton, T | 1 |
| Marshal, ML | 1 |
| Knuckey, NW | 1 |
| Stokes, BA | 1 |
| Kato, M | 1 |
| Iwata, H | 1 |
| Katayama, T | 1 |
| Asai, H | 1 |
| Narita, H | 1 |
| Endo, T | 1 |
| Nagai, H | 1 |
| Mabe, H | 2 |
| Furuse, M | 1 |
| Takagi, T | 1 |
| Sundt, TM | 1 |
| Szurszewski, J | 1 |
| Sharbrough, FW | 1 |
| Zervas, NT | 5 |
| Candia, M | 1 |
| Candia, G | 1 |
| Kido, D | 1 |
| Pessin, MS | 1 |
| Rosoff, CB | 3 |
| Bacon, V | 1 |
| Tanabe, Y | 2 |
| Sakata, K | 2 |
| Yamada, H | 2 |
| Ito, T | 1 |
| Takada, M | 2 |
| Kagawa, Y | 1 |
| Iwai, R | 1 |
| Endo, S | 1 |
| Kamiyama, K | 1 |
| Otsuji, T | 1 |
| Sugita, T | 1 |
| Takaku, A | 1 |
| Hori, H | 1 |
| Kuwayama, A | 1 |
| Salzman, EW | 1 |
| Dawson, WN | 1 |
| White, RP | 1 |
| Robertson, JT | 1 |
| Gottstein, U | 1 |
| Finnerty, FA | 1 |
| Allcock, JM | 1 |
2 reviews available for reserpine and Ischemic Attack, Transient
| Article | Year |
|---|---|
Physiological considerations important for the management of vasospasm.
Topics: Albuterol; Aminophylline; Autonomic Nervous System; Blood Pressure; Cerebrovascular Circulation; Hum | 1977 |
Vasospasm: an update.
Topics: Angiotensin II; Animals; Blood; Cerebral Angiography; Cerebral Arteries; Diagnosis, Differential; Di | 1979 |
1 trial available for reserpine and Ischemic Attack, Transient
| Article | Year |
|---|---|
Reduced incidence of cerebral ischemia following rupture of intracranial aneurysms.
Topics: Cerebral Infarction; Clinical Trials as Topic; Humans; Intracranial Aneurysm; Ischemic Attack, Trans | 1979 |
16 other studies available for reserpine and Ischemic Attack, Transient
| Article | Year |
|---|---|
[Clinical studies of the vasodilating activity of a new drug with adrenosympatholytic action].
Topics: Adult; Aged; Arteriosclerosis; Endarteritis; Ergot Alkaloids; Female; Heart Diseases; Humans; Intrac | 1967 |
Effect of reserpine-kanamycin treatment on chronic vasospasm after platelet-enriched subarachnoid hemorrhage in primates.
Topics: Animals; Blood Platelets; Chronic Disease; Drug Therapy, Combination; Female; Ischemic Attack, Trans | 1984 |
Medical management of patients following a ruptured cerebral aneurysm, with epsilon-aminocaproic acid, kanamycin, and reserpine.
Topics: Aminocaproates; Aminocaproic Acid; Drug Therapy, Combination; Female; Humans; Intracranial Aneurysm; | 1982 |
Possible therapeutic effect of T-794, a novel reversible inhibitor of monoamine oxidase-A, on post-stroke emotional disturbances, assessed in animal models of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Body Temperature; Depression; Disease Models, Anim | 1997 |
The role of sympathetic nerve and vasoactive amines in cerebral vasospasm.
Topics: Animals; Cerebral Arteries; Dogs; Ischemic Attack, Transient; Reserpine; Sympathectomy; Sympathetic | 1977 |
Prevention of ischemic infarction following rupture of intracranial aneurysms.
Topics: Humans; Intracranial Aneurysm; Intracranial Embolism and Thrombosis; Ischemic Attack, Transient; Kan | 1977 |
Cerebral vasospasm and ultrastructural changes in cerebral arterial wall. An experimental study.
Topics: Blood; Cerebral Arteries; Injections; Ischemic Attack, Transient; Optic Chiasm; Reserpine; Time Fact | 1978 |
[The role of sympathetic nerve and vasoactive amines in experimental cerebral vasospasm in dogs (author's transl)].
Topics: Animals; Basilar Artery; Dogs; Ischemic Attack, Transient; Norepinephrine; Radiography; Reserpine; S | 1978 |
[Ultrastructural changes in cerebral arterial wall and cerebral vasopasm--an experimental study (author's transl)].
Topics: Animals; Basilar Artery; Dogs; Ischemic Attack, Transient; Muscle, Smooth; Necrosis; Norepinephrine; | 1978 |
[Experimental cerebral vasospasm induced by oxyhemoglobin and the sympathetic nervous system (Part 2): An investigation into denervation supersensitivity].
Topics: Animals; Cats; Cerebrovascular Circulation; Hydroxydopamines; Ischemic Attack, Transient; Norepineph | 1988 |
Experimental inhibition of serotonin by antibiotic: prevention of cerebral vasospasm.
Topics: Animals; Cerebral Angiography; Disease Models, Animal; Evaluation Studies as Topic; Haplorhini; Isch | 1974 |
Cerebral arterial spasm. Modification by inhibition of platelet function.
Topics: Angiotensin II; Animals; Basilar Artery; Blood Platelets; Bradykinin; Brain; Catecholamines; Cats; C | 1973 |
Pharmacologic determination of the role of autonomic receptor sites in cerebral vasospasm.
Topics: Angiography; Animals; Atropine; Basilar Artery; Brain Stem; Catecholamines; Dogs; Ganglia, Autonomic | 1973 |
[Therapy of circulatory disorders of the brain and spinal cord].
Topics: Age Factors; Anticoagulants; Brain Edema; Cerebral Hemorrhage; Cerebrovascular Disorders; Coronary D | 1969 |
Hypertensive encephalopathy.
Topics: Brain Diseases; Cerebrovascular Circulation; Cerebrovascular Disorders; Coma; Diagnosis, Differentia | 1968 |
Arterial spasm in subarachnoid haemorrhage. A clinical and experimental study.
Topics: Animals; Cerebral Angiography; Dogs; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Meth | 1966 |