Page last updated: 2024-11-06

reserpine and Intracranial Aneurysm

reserpine has been researched along with Intracranial Aneurysm in 9 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (

Research Excerpts

ExcerptRelevanceReference
"A randomized study was carried out to determine if the administration of reserpine and kanamycin to lower the concentration of vasoactive biogenic monoamines would reduce the incidence of cerebral vascular ischemic complications and death following the rupture of intracranial aneurysms."5.04Reduced incidence of cerebral ischemia following rupture of intracranial aneurysms. ( Bacon, V; Candia, G; Candia, M; Kido, D; Pessin, MS; Rosoff, CB; Zervas, NT, 1979)
"Patients suffering from a subarachnoid hemorrhage who were admitted to the Neurosurgical Unit of the Royal Perth Hospital during the period 1971 to 1979 were assessed with regard to the effectiveness of preoperative treatment with epsilon-aminocaproic acid, kanamycin, and reserpine."3.66Medical management of patients following a ruptured cerebral aneurysm, with epsilon-aminocaproic acid, kanamycin, and reserpine. ( Knuckey, NW; Stokes, BA, 1982)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Knuckey, NW1
Stokes, BA1
Sundt, TM1
Szurszewski, J1
Sharbrough, FW1
Zervas, NT3
Candia, M1
Candia, G1
Kido, D1
Pessin, MS1
Rosoff, CB1
Bacon, V1
Robertson, JT1
Fink, M1
Abrams, R1
Allcock, JM1

Reviews

3 reviews available for reserpine and Intracranial Aneurysm

ArticleYear
Physiological considerations important for the management of vasospasm.
    Surgical neurology, 1977, Volume: 7, Issue:5

    Topics: Albuterol; Aminophylline; Autonomic Nervous System; Blood Pressure; Cerebrovascular Circulation; Hum

1977
Vasospasm: an update.
    Clinical neurosurgery, 1979, Volume: 26

    Topics: Angiotensin II; Animals; Blood; Cerebral Angiography; Cerebral Arteries; Diagnosis, Differential; Di

1979
Cerebral arterial spasm: current concepts.
    Clinical neurosurgery, 1974, Volume: 21

    Topics: Anesthesia, General; Animals; Blood Coagulation; Blood Platelets; Brain; Catecholamines; Cerebral Ar

1974

Trials

1 trial available for reserpine and Intracranial Aneurysm

ArticleYear
Reduced incidence of cerebral ischemia following rupture of intracranial aneurysms.
    Surgical neurology, 1979, Volume: 11, Issue:5

    Topics: Cerebral Infarction; Clinical Trials as Topic; Humans; Intracranial Aneurysm; Ischemic Attack, Trans

1979

Other Studies

5 other studies available for reserpine and Intracranial Aneurysm

ArticleYear
Medical management of patients following a ruptured cerebral aneurysm, with epsilon-aminocaproic acid, kanamycin, and reserpine.
    Surgical neurology, 1982, Volume: 17, Issue:3

    Topics: Aminocaproates; Aminocaproic Acid; Drug Therapy, Combination; Female; Humans; Intracranial Aneurysm;

1982
Prevention of ischemic infarction following rupture of intracranial aneurysms.
    Transactions of the American Neurological Association, 1977, Volume: 102

    Topics: Humans; Intracranial Aneurysm; Intracranial Embolism and Thrombosis; Ischemic Attack, Transient; Kan

1977
Attempts at vasospasm control.
    JAMA, 1978, Nov-10, Volume: 240, Issue:20

    Topics: Blood Vessels; Humans; Intracranial Aneurysm; Kanamycin; Reserpine; Rupture, Spontaneous; Spasm

1978
Answers to questions frequently asked about ECT.
    Seminars in psychiatry, 1972, Volume: 4, Issue:1

    Topics: Age Factors; Anesthesia, Intravenous; Brain Damage, Chronic; Brain Neoplasms; Depression; Electrocon

1972
Arterial spasm in subarachnoid haemorrhage. A clinical and experimental study.
    Acta radiologica: diagnosis, 1966, Volume: 5

    Topics: Animals; Cerebral Angiography; Dogs; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Meth

1966