reserpine has been researched along with Intellectual Disability in 30 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| NOCE, RH | 1 |
| WILLIAMS, DB | 1 |
| RAPAPORT, W | 1 |
| GEYER, HW | 1 |
| JENSEN, ES | 2 |
| KIRK, DL | 1 |
| BAUER, AM | 1 |
| CARTER, CH | 1 |
| HORENSTEIN, S | 2 |
| BELEY, A | 2 |
| FONCIN, JF | 2 |
| LEYRIE, J | 2 |
| SPROGIS, GR | 1 |
| LEZDINS, V | 1 |
| WHITE, SD | 1 |
| MING, C | 1 |
| LANNING, M | 1 |
| DRAKE, ME | 1 |
| WYCKOFF, G | 1 |
| CAMPIONI, T | 1 |
| FOIS, M | 1 |
| D'ARGENIO, L | 1 |
| GIOVANNELLI, G | 1 |
| TIMBERLAKE, WH | 1 |
| BELMONT, EH | 1 |
| OGONIK, J | 1 |
| PALLISTER, PD | 1 |
| STEVENS, RR | 1 |
| WOLFSON, IN | 1 |
| JOHNSTON, AH | 1 |
| MARTIN, CH | 1 |
| ROSENBLUM, S | 2 |
| CALLAHAN, RJ | 2 |
| BUONICONTO, P | 1 |
| GRAHAM, B | 1 |
| DEATRICK, RW | 1 |
| WARDELL, DW | 1 |
| RUBIN, HK | 1 |
| ROSS, RT | 1 |
| GRAHAM, BD | 1 |
| ZIMMERMAN, FT | 2 |
| BURGEMEISTER, BB | 2 |
| TRIPI, E | 1 |
| NISHIKAWA, M | 1 |
| LOUTTIT, RT | 1 |
| SCHILLER, H | 1 |
| Itil, TM | 1 |
| Wadud, A | 1 |
| Martsinkevich, NE | 1 |
| Pozdeev, VK | 1 |
| Hanley, HG | 1 |
| Stahl, SM | 1 |
| Freedman, DX | 1 |
| Singh, NN | 1 |
| Millichamp, CJ | 1 |
| Blazsó, S | 1 |
| Woolley, DW | 1 |
| Van der Hoeven, T | 1 |
2 reviews available for reserpine and Intellectual Disability
| Article | Year |
|---|---|
Treatment of human aggression with major tranquilizers, antidepressants, and newer psychotropic drugs.
Topics: Adolescent; Affective Symptoms; Aggression; Alcoholism; Antidepressive Agents; Antipsychotic Agents; | 1975 |
Pharmacological treatment of self-injurious behavior in mentally retarded persons.
Topics: Adolescent; Anti-Anxiety Agents; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Double-Blind | 1985 |
28 other studies available for reserpine and Intellectual Disability
| Article | Year |
|---|---|
Reserpine (serpasil) in the management of the mentally ill and mentally retarded; preliminary report.
Topics: Electroconvulsive Therapy; Humans; Intellectual Disability; Mental Disorders; Mentally Ill Persons; | 1954 |
Thorazine (chlorpromazine) and serpasil therapy in hyperactive patient of low mentality.
Topics: Behavior; Chlorpromazine; Intellectual Disability; Reserpine | 1955 |
[Serpasil therapy in a hospital for the mentally deficient].
Topics: Antihypertensive Agents; Diet, Reducing; Hospitals; Intellectual Disability; Reserpine; Secologanin | 1955 |
Effects of reserpine (serpasil) on emotionally maladjusted high grade mental retardates.
Topics: Antihypertensive Agents; Emotions; Euphoria; Intellectual Disability; Mental Disorders; Reserpine; S | 1956 |
The effects of reserpine and methylphenidylacetate (ritalin) in mental defectives, spastics, and epileptics.
Topics: Antihypertensive Agents; Diet, Reducing; Epilepsy; Intellectual Disability; Methylphenidate; Muscle | 1956 |
Reserpine and chlorpromazine in hyperactive mental defectives.
Topics: Chlorpromazine; Diet, Reducing; Hyperkinesis; Intellectual Disability; Reserpine | 1957 |
Reserpine and chlorpromazine in hyperactive mental defectives.
Topics: Chlorpromazine; Diet, Reducing; Hyperkinesis; Intellectual Disability; Reserpine | 1957 |
Reserpine and chlorpromazine in hyperactive mental defectives.
Topics: Chlorpromazine; Diet, Reducing; Hyperkinesis; Intellectual Disability; Reserpine | 1957 |
Reserpine and chlorpromazine in hyperactive mental defectives.
Topics: Chlorpromazine; Diet, Reducing; Hyperkinesis; Intellectual Disability; Reserpine | 1957 |
[Complications of high doses of reserpine for the disturbed retarded child; indication for doses].
Topics: Humans; Intellectual Disability; Reserpine | 1956 |
[Complications of high doses of reserpine for the disturbed retarded child; indication for doses].
Topics: Humans; Intellectual Disability; Reserpine | 1956 |
[Complications of high doses of reserpine for the disturbed retarded child; indication for doses].
Topics: Humans; Intellectual Disability; Reserpine | 1956 |
[Complications of high doses of reserpine for the disturbed retarded child; indication for doses].
Topics: Humans; Intellectual Disability; Reserpine | 1956 |
Comparative study on thorazine and serpasil in the mental defective.
Topics: Chlorpromazine; Diet, Reducing; Intellectual Disability; Reserpine | 1957 |
[Early results of largactil and serpasil therapy of a group of mentally handicapped children with abnormalities of character].
Topics: Chlorpromazine; Diet, Reducing; Disabled Children; Disabled Persons; Intellectual Disability; Reserp | 1956 |
[Liver function tests in a group of mentally handicapped children treated with largactil and serpasil].
Topics: Chlorpromazine; Diet, Reducing; Disabled Children; Disabled Persons; Intellectual Disability; Liver; | 1956 |
Serpasil treatment in a hospital for the mentally deficient.
Topics: Diet, Reducing; Hospitals; Intellectual Disability; Persons with Mental Disabilities; Reserpine | 1957 |
The effect of reserpine in 200 mentally retarded children.
Topics: Diet, Reducing; Intellectual Disability; Persons with Mental Disabilities; Reserpine | 1957 |
Effects of serpasil in small dosage on behavior, intelligence and physiology.
Topics: Diet, Reducing; Intellectual Disability; Intelligence; Reserpine | 1957 |
Clinical experience with serpasil and thorazine in treatment of disturbed behavior of mentally retarded.
Topics: Attention Deficit and Disruptive Behavior Disorders; Behavior; Child; Child Behavior Disorders; Chlo | 1957 |
The clinical use of reserpine and chlorpromazine in the care of the mentally deficient.
Topics: Chlorpromazine; Diet, Reducing; Intellectual Disability; Persons with Mental Disabilities; Reserpine | 1957 |
The effects of tranquillizing medication (reserpine) on behavior and test performance of maladjusted, high-grade retarded children.
Topics: Diet, Reducing; Intellectual Disability; Mental Disorders; Reserpine; Tranquilizing Agents | 1958 |
The use of reserpine and chlorpromazine in disturbed mentally deficient patients.
Topics: Chlorpromazine; Intellectual Disability; Persons with Mental Disabilities; Reserpine | 1958 |
Placebo-controlled study of reserpine in maladjusted retarded children.
Topics: Behavior; Double-Blind Method; Intellectual Disability; Mental Disorders; Reserpine | 1958 |
A controlled experiment of glutamic acid therapy; first report summarizing thirteen years of study.
Topics: Diet, Reducing; Glutamates; Glutamic Acid; Intellectual Disability; Reserpine | 1959 |
[CRITICAL NOTE ON THE USEFULNESS OF A NEW DRUG, THE METHYL ETHER OF METHYL 18-EPIRESERPATE, IN PSYCHIATRY].
Topics: Biomedical Research; Depression; Epilepsy; Humans; Intellectual Disability; Mental Disorders; Methyl | 1963 |
[THE CENTRAL NERVOUS SYSTEM AND THE PITUITARY-ADRENAL SYSTEM].
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Benzothiadiazines; | 1964 |
CHEMICAL FACILITATION OF INTELLIGENCE AMONG THE MENTALLY RETARDED.
Topics: Autonomic Agents; Central Nervous System Stimulants; Chlorpromazine; Chorionic Gonadotropin; Drug Th | 1965 |
Preliminary report upon the effect of reserpine on epilepsy and behavior problems in children.
Topics: Antihypertensive Agents; Behavior; Epilepsy; Intellectual Disability; Mental Disorders; Reserpine; S | 1955 |
Reserpine, chlorpromazine and the mentally retarded. A report on 139 cases.
Topics: Chlorpromazine; Humans; Intellectual Disability; Persons with Mental Disabilities; Reserpine | 1959 |
[Serotonin metabolism in children with different forms of oligophrenia].
Topics: Child; Humans; Hydroxyindoleacetic Acid; Intellectual Disability; Reserpine; Serotonin | 1977 |
Hyperserotonemia and amine metabolites in autistic and retarded children.
Topics: Adolescent; Adult; Age Factors; Autistic Disorder; Child; Child, Institutionalized; Child, Preschool | 1977 |
[On the pharmacotherapeutic treatment of cerebral palsy. II. Treatment of oligophrenia and epilepsy].
Topics: Cerebral Palsy; Child; Child, Preschool; Chlorpromazine; Epilepsy; Epilepsy, Absence; Glutamates; Hu | 1965 |
Serotonin deficiency in infancy as a cause of a mental defect in experimental phenylketonuria.
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Chlorpromazine; Electroshock; Female; Humans; In Vit | 1965 |