reserpine has been researched along with Inflammation in 19 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study aimed to evaluate the anti-depressant effect of Cerebrolysin (CBL) in Reserpine-induced depressed rats, its effect on oxidative stress, inflammation, regulatory cyclic AMP-dependent response element binding protein (CREB)/brain derived neurotropic factor (BDNF) signaling pathways, brain monoamines and histopathological changes was assessed." | 8.02 | Anti-depressant effect of cerebrolysin in reserpine-induced depression in rats: Behavioral, biochemical, molecular and immunohistochemical evidence. ( Ahmed-Farid, OA; El Awdan, SA; El-Marasy, SA; Hassan, A; Ogaly, HA, 2021) |
| "Repeated reserpine injection induced hyperalgesia and depressive behaviors with decreased sucrose preference and horizontal movement distance, and increased immobility time in forced swimming test." | 5.72 | Alterations of monoamine neurotransmitters, HPA-axis hormones, and inflammation cytokines in reserpine-induced hyperalgesia and depression comorbidity rat model. ( Du, Y; Gao, X; Li, L; Lu, Y; Shi, W; Wang, A; Wang, Y; Zhang, S; Zhao, J, 2022) |
| "Obesity is associated with low-grade chronic inflammation and oxidative stress, affecting the brain's reward system by decreasing dopaminergic neurotransmission." | 5.72 | Effects of obesity on neuroinflammatory and neurochemical parameters in an animal model of reserpine-induced Parkinson's disease. ( Andrade, VM; Bitencourt, RM; Cavalheiro, EKFF; Cucker, L; da Silva, LE; Dal-Pizzol, F; Damiani, AP; Joaquim, L; Machado, RS; Magenis, ML; Michels, M; Oliveira, MP; Petronilho, F; Rezin, GT; Ribeiro, CB; Silva, MG; Tuon, T; Vilela, TC, 2022) |
| "Fibromyalgia is a chronic syndrome characterized by widespread musculoskeletal pain and an extensive array of other symptoms including disordered sleep, fatigue, depression and anxiety." | 5.46 | Oral Supplementation of Melatonin Protects against Fibromyalgia-Related Skeletal Muscle Alterations in Reserpine-Induced Myalgia Rats. ( Bonomini, F; Favero, G; Lavazza, A; Rezzani, R; Rodella, LF; Stacchiotti, A; Trapletti, V, 2017) |
| "Reserpine treatment in doses of 1." | 5.27 | Reserpine and the suppression of both edema formation and cellular infiltrate of the contact sensitivity reaction in the mouse. ( Bäck, O; Groth, O, 1983) |
| " This study aimed to evaluate the anti-depressant effect of Cerebrolysin (CBL) in Reserpine-induced depressed rats, its effect on oxidative stress, inflammation, regulatory cyclic AMP-dependent response element binding protein (CREB)/brain derived neurotropic factor (BDNF) signaling pathways, brain monoamines and histopathological changes was assessed." | 4.02 | Anti-depressant effect of cerebrolysin in reserpine-induced depression in rats: Behavioral, biochemical, molecular and immunohistochemical evidence. ( Ahmed-Farid, OA; El Awdan, SA; El-Marasy, SA; Hassan, A; Ogaly, HA, 2021) |
| " To determine whether mast cells are also important for the development of an immune-mediated inflammatory response across the endothelial tight junctions of the blood-brain barrier, the development of mononuclear inflammation in the central nervous system of reserpine-treated mice and mast cell-deficient mice (WBB6F1-W/Wv) was studied after infection with Sindbis virus." | 3.67 | The role of mast cells in virus-induced inflammation in the murine central nervous system. ( Griffin, DE; Mokhtarian, F, 1984) |
| "Repeated reserpine injection induced hyperalgesia and depressive behaviors with decreased sucrose preference and horizontal movement distance, and increased immobility time in forced swimming test." | 1.72 | Alterations of monoamine neurotransmitters, HPA-axis hormones, and inflammation cytokines in reserpine-induced hyperalgesia and depression comorbidity rat model. ( Du, Y; Gao, X; Li, L; Lu, Y; Shi, W; Wang, A; Wang, Y; Zhang, S; Zhao, J, 2022) |
| "Obesity is associated with low-grade chronic inflammation and oxidative stress, affecting the brain's reward system by decreasing dopaminergic neurotransmission." | 1.72 | Effects of obesity on neuroinflammatory and neurochemical parameters in an animal model of reserpine-induced Parkinson's disease. ( Andrade, VM; Bitencourt, RM; Cavalheiro, EKFF; Cucker, L; da Silva, LE; Dal-Pizzol, F; Damiani, AP; Joaquim, L; Machado, RS; Magenis, ML; Michels, M; Oliveira, MP; Petronilho, F; Rezin, GT; Ribeiro, CB; Silva, MG; Tuon, T; Vilela, TC, 2022) |
| "Fibromyalgia is a chronic syndrome characterized by widespread musculoskeletal pain and an extensive array of other symptoms including disordered sleep, fatigue, depression and anxiety." | 1.46 | Oral Supplementation of Melatonin Protects against Fibromyalgia-Related Skeletal Muscle Alterations in Reserpine-Induced Myalgia Rats. ( Bonomini, F; Favero, G; Lavazza, A; Rezzani, R; Rodella, LF; Stacchiotti, A; Trapletti, V, 2017) |
| "Reserpine treatment in doses of 1." | 1.27 | Reserpine and the suppression of both edema formation and cellular infiltrate of the contact sensitivity reaction in the mouse. ( Bäck, O; Groth, O, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (63.16) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 4 (21.05) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Song, JH | 1 |
| Won, SK | 1 |
| Eom, GH | 1 |
| Lee, DS | 1 |
| Park, BJ | 1 |
| Lee, JS | 1 |
| Son, CG | 1 |
| Park, JY | 1 |
| Zhao, J | 1 |
| Shi, W | 1 |
| Lu, Y | 1 |
| Gao, X | 1 |
| Wang, A | 1 |
| Zhang, S | 1 |
| Du, Y | 1 |
| Wang, Y | 1 |
| Li, L | 1 |
| Cavalheiro, EKFF | 1 |
| da Silva, LE | 1 |
| Oliveira, MP | 1 |
| Silva, MG | 1 |
| Damiani, AP | 1 |
| Ribeiro, CB | 1 |
| Magenis, ML | 1 |
| Cucker, L | 1 |
| Michels, M | 1 |
| Joaquim, L | 1 |
| Machado, RS | 1 |
| Vilela, TC | 1 |
| Bitencourt, RM | 1 |
| Andrade, VM | 1 |
| Dal-Pizzol, F | 1 |
| Petronilho, F | 1 |
| Tuon, T | 1 |
| Rezin, GT | 1 |
| El-Marasy, SA | 1 |
| El Awdan, SA | 1 |
| Hassan, A | 1 |
| Ahmed-Farid, OA | 1 |
| Ogaly, HA | 1 |
| Favero, G | 1 |
| Trapletti, V | 1 |
| Bonomini, F | 1 |
| Stacchiotti, A | 1 |
| Lavazza, A | 1 |
| Rodella, LF | 1 |
| Rezzani, R | 1 |
| PENN, GB | 1 |
| ASHFORD, A | 1 |
| ARRIGONIMARTELLI, E | 1 |
| CONTI, I | 1 |
| Amico-Roxas, M | 1 |
| Caruso, A | 1 |
| Trombadore, S | 1 |
| Scifo, R | 1 |
| Scapagnini, U | 1 |
| Mokhtarian, F | 1 |
| Griffin, DE | 1 |
| Bäck, O | 1 |
| Groth, O | 1 |
| Tozawa, Y | 1 |
| Matsushima, K | 1 |
| Hirschelmann, R | 1 |
| Bekemeier, H | 1 |
| Metzner, J | 1 |
| Giessler, AJ | 1 |
| Stelzner, A | 1 |
| Rose, ML | 1 |
| Parrott, DM | 1 |
| Goth, A | 1 |
| De Cato, L | 1 |
| Brown, JK | 1 |
| Malone, MH | 1 |
| Wiedermann, D | 1 |
| Hromek, F | 1 |
| Vasků, J | 1 |
| Cídl, K | 1 |
| Mitova, M | 1 |
| Creasey, NH | 1 |
| Allenby, AC | 1 |
| Schock, C | 1 |
| Douglas, BH | 1 |
| Clower, BR | 1 |
1 review available for reserpine and Inflammation
| Article | Year |
|---|---|
Effect of drugs on mast cells.
Topics: Adrenal Cortex Hormones; Amines; Anaphylaxis; Animals; Anti-Inflammatory Agents; Brain; Carbohydrate | 1967 |
18 other studies available for reserpine and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Improvement Effects of Myelophil on Symptoms of Chronic Fatigue Syndrome in a Reserpine-Induced Mouse Model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Calcium-Binding Proteins; Corpus | 2021 |
Alterations of monoamine neurotransmitters, HPA-axis hormones, and inflammation cytokines in reserpine-induced hyperalgesia and depression comorbidity rat model.
Topics: Adrenocorticotropic Hormone; Animals; Comorbidity; Cytokines; Depression; Hydrocortisone; Hyperalges | 2022 |
Effects of obesity on neuroinflammatory and neurochemical parameters in an animal model of reserpine-induced Parkinson's disease.
Topics: Animals; Disease Models, Animal; Inflammation; Obesity; Oxidative Stress; Parkinson Disease; Reserpi | 2022 |
Anti-depressant effect of cerebrolysin in reserpine-induced depression in rats: Behavioral, biochemical, molecular and immunohistochemical evidence.
Topics: Amino Acids; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Cyc | 2021 |
Oral Supplementation of Melatonin Protects against Fibromyalgia-Related Skeletal Muscle Alterations in Reserpine-Induced Myalgia Rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Antioxidants; Body Weight; Disease Models, Anim | 2017 |
THE INFLAMMATORY RESPONSE TO IMPLANTATION OF COTTON PELLETS IN THE RAT.
Topics: Cotton Fiber; Granulation Tissue; Granuloma; Hydrocortisone; Inflammation; Irritants; Lysergic Acid | 1963 |
[RESEARCH ON A NEW METHOD OF EXPERIMENTAL INFLAMMATION: SUBPLANTAR EDEMA CAUSED BY CARRAGEENIN].
Topics: Adrenalectomy; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Carrageenan; Chlorpheniramine; Ch | 1964 |
Gangliosides antinociceptive effects in rodents.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; | 1984 |
The role of mast cells in virus-induced inflammation in the murine central nervous system.
Topics: Animals; Cell Line; Central Nervous System Diseases; Cricetinae; Hypersensitivity, Delayed; Inflamma | 1984 |
Reserpine and the suppression of both edema formation and cellular infiltrate of the contact sensitivity reaction in the mouse.
Topics: Animals; Cell Differentiation; Dermatitis, Contact; Edema; Immunosuppressive Agents; Inflammation; M | 1983 |
Peripheral 5-HT(2A)-receptor-mediated formation of an inhibitor of atrial natriuretic peptide binding involves inflammation.
Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Atrial Natriuretic Factor; Catecholamin | 2002 |
[Modification of the adjuvans arthritis by carrageenin, compound 48/80, histamine- and serotonin antagonists, non-steroid antiphlogistics as well as protease inhibitors and their possible relations to inflammation mediators].
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carrageenan; Chlorpromazine; Cyproheptadin | 1975 |
Vascular permeability and lymphoblast extravasation into inflamed skin are not related.
Topics: Animals; Capillary Permeability; Cell Movement; Female; Inflammation; Male; Mice; Mice, Inbred BALB | 1977 |
Effects of benzoquinolizine homologues on proliferative and exudative inflammation.
Topics: Adrenal Glands; Animals; Anti-Inflammatory Agents; Body Weight; Carrageenan; Catecholamines; Chlorpr | 1974 |
[Reserpine and the changes in the serum sialic acid level in experimental inflammation].
Topics: Animals; Disease Models, Animal; Glycoproteins; Inflammation; Neuraminic Acids; Rabbits; Reserpine | 1972 |
Mechanism of action of accelerants. The effect of cutaneously-applied penetration accelerants on the skin circulation of the rat.
Topics: Amines; Animals; Capillary Permeability; Cold Temperature; Dimethyl Sulfoxide; Ear; Epinephrine; Fur | 1971 |
Hepatotoxic effect of carbon tetrachloride during pregnancy.
Topics: Animals; Carbon Tetrachloride Poisoning; Female; Inflammation; Injections, Subcutaneous; Liver; Necr | 1968 |