reserpine has been researched along with Infections, Staphylococcal in 14 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hazards of antibiotic therapy include: the increasing incidence of sensitization to penicillin with occasional anaphylactic reactions; aplastic anemia with chloramphenicol, and the poor tolerance of infants for chloramphenicol; staphylococcal enterocolitis; unnecessary "prophylactic" use of antibiotics." | 3.64 | Dangers in the use of some potent drugs. ( SPAULDING, WB, 1962) |
| "When nafcillin was added, only cortisol, Dilantin, nicotinamide and reserpine were found to prolong life significantly compared to nafcillin-saline treatment Fatality rates were significantly reduced with cortisol and Dilantin when they were given in association with nafcillin compared to nafcillin-saline treatment." | 1.26 | Biochemically assisted antibiotic treatment of lethal murine Staphylococcus aureus septic shock. ( Burmeister, LF; Smith, IM, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Fleeman, R | 1 |
| LaVoi, TM | 1 |
| Santos, RG | 1 |
| Morales, A | 1 |
| Nefzi, A | 1 |
| Welmaker, GS | 1 |
| Medina-Franco, JL | 1 |
| Giulianotti, MA | 1 |
| Houghten, RA | 1 |
| Shaw, LN | 1 |
| Fontaine, F | 1 |
| Héquet, A | 1 |
| Voisin-Chiret, AS | 1 |
| Bouillon, A | 1 |
| Lesnard, A | 1 |
| Cresteil, T | 1 |
| Jolivalt, C | 1 |
| Rault, S | 1 |
| Astolfi, A | 1 |
| Felicetti, T | 3 |
| Iraci, N | 1 |
| Manfroni, G | 2 |
| Massari, S | 2 |
| Pietrella, D | 3 |
| Tabarrini, O | 2 |
| Kaatz, GW | 3 |
| Barreca, ML | 2 |
| Sabatini, S | 3 |
| Cecchetti, V | 2 |
| Cannalire, R | 1 |
| Latacz, G | 1 |
| Lubelska, A | 1 |
| Kieć-Kononowicz, K | 1 |
| Schindler, BD | 1 |
| Rampacci, E | 1 |
| Passamonti, F | 1 |
| Parai, D | 1 |
| Banerjee, M | 1 |
| Dey, P | 1 |
| Mukherjee, SK | 1 |
| Saiful, AJ | 1 |
| Mastura, M | 1 |
| Zarizal, S | 1 |
| Mazurah, MI | 1 |
| Shuhaimi, M | 1 |
| Ali, AM | 1 |
| Frempong-Manso, E | 1 |
| Raygada, JL | 1 |
| DeMarco, CE | 1 |
| Seo, SM | 1 |
| SUGIYAMA, H | 1 |
| BERGDOLL, MS | 1 |
| WILKERSON, RG | 1 |
| SPAULDING, WB | 1 |
| Schmitz, FJ | 2 |
| Fluit, AC | 2 |
| Lückefahr, M | 1 |
| Engler, B | 1 |
| Hofmann, B | 1 |
| Verhoef, J | 2 |
| Heinz, HP | 1 |
| Hadding, U | 1 |
| Jones, ME | 1 |
| Brisse, S | 1 |
| Köhrer, K | 1 |
| Milatovic, D | 1 |
| Smith, IM | 1 |
| Burmeister, LF | 1 |
| Jewett, JF | 1 |
14 other studies available for reserpine and Infections, Staphylococcal
| Article | Year |
|---|---|
Combinatorial Libraries As a Tool for the Discovery of Novel, Broad-Spectrum Antibacterial Agents Targeting the ESKAPE Pathogens.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cell Line; Drug Discovery; Guanidine | 2015 |
Boronic species as promising inhibitors of the Staphylococcus aureus NorA efflux pump: study of 6-substituted pyridine-3-boronic acid derivatives.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Boronic Acids; Ciprofloxacin; Humans; KB Cells; Multidrug | 2015 |
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Repositioning; Humans; Ligands; Models, Molecular; M | 2017 |
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Hep G2 Cells; Humans; Microbi | 2018 |
Drug efflux transporters in Staphylococcus pseudintermedius: in silico prediction and characterization of resistance.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Membrane Transport Proteins; Microbial Sensitivity Tests; | 2022 |
Reserpine attenuates biofilm formation and virulence of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Chemical Phenomena; Dose-Response Relationship, | 2020 |
Efflux genes and active efflux activity detection in Malaysian clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA).
Topics: Anti-Bacterial Agents; Bacterial Proteins; DNA, Bacterial; Ethidium; Malaysia; Membrane Transport Pr | 2008 |
Inability of a reserpine-based screen to identify strains overexpressing efflux pump genes in clinical isolates of Staphylococcus aureus.
Topics: Bacteremia; Drug Resistance, Multiple, Bacterial; Gene Expression Profiling; Humans; Membrane Transp | 2009 |
Perphenazine and reserpine as antiemetics for staphylococcal enterotoxin.
Topics: Antiemetics; Enterotoxins; Humans; Perphenazine; Reserpine; Staphylococcal Infections | 1960 |
Dangers in the use of some potent drugs.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antihypertensive Agents; Antipsychotic Agents; Chlor | 1962 |
The effect of reserpine, an inhibitor of multidrug efflux pumps, on the in-vitro activities of ciprofloxacin, sparfloxacin and moxifloxacin against clinical isolates of Staphylococcus aureus.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; G | 1998 |
Molecular epidemiology of quinolone resistance and comparative in vitro activities of new quinolones against European Staphylococcus aureus isolates.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; | 1999 |
Biochemically assisted antibiotic treatment of lethal murine Staphylococcus aureus septic shock.
Topics: Animals; Drug Synergism; Hydrocortisone; Mice; Nafcillin; Niacinamide; Phenytoin; Reserpine; Shock, | 1977 |
Committee on Maternal Welfare. Staphylococcal bronchopneumonia.
Topics: Bronchopneumonia; Female; Humans; Hydrochlorothiazide; Hypertension; Pregnancy; Pregnancy Complicati | 1971 |