reserpine has been researched along with Hypokalemia in 16 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " To determine whether thiazide-induced diabetes is mediated by changes in potassium, we analyzed data from 3790 nondiabetic participants in the Systolic Hypertension in Elderly Program, a randomized clinical trial of isolated systolic hypertension in individuals aged >or=60 years treated with chlorthalidone or placebo." | 5.13 | Changes in serum potassium mediate thiazide-induced diabetes. ( Appel, LJ; Klag, MJ; Miller, ER; Parekh, RS; Shafi, T, 2008) |
| "In a study of 50 patients with uncomplicated arterial hypertension the administration of hydrochlorothiazide, 50 to 100 mg daily or every other day, with or without reserpine, 0." | 3.66 | Hypokalemia during the treatment of arterial hypertension with diuretics. ( Beauchemin, M; Gougoux, A; Lemieux, G; Vinay, P, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (93.75) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shafi, T | 1 |
| Appel, LJ | 1 |
| Miller, ER | 1 |
| Klag, MJ | 1 |
| Parekh, RS | 1 |
| PEDERSEN, J | 1 |
| LINDENEG, O | 1 |
| FISCHER, S | 1 |
| Lemieux, G | 1 |
| Beauchemin, M | 1 |
| Vinay, P | 1 |
| Gougoux, A | 1 |
| Shapiro, AP | 1 |
| Traub, YM | 1 |
| Ohmae, M | 1 |
| Nohara, Y | 1 |
| Takayasu, M | 1 |
| Saimyoji, H | 1 |
| Seriu, Y | 1 |
| Lukomskiĭ, GI | 1 |
| Ivanova, NA | 1 |
| Krivenko, NG | 1 |
| Freis, ED | 2 |
| Tomov, I | 1 |
| Munro, AB | 1 |
| Woods, JW | 1 |
| Resnick, JS | 1 |
| Dorman, JD | 1 |
| Engel, WK | 1 |
| Kalliomäki, JL | 1 |
| Kasanen, A | 1 |
| Leon, AS | 1 |
| Abrams, WB | 1 |
| Schmitz, S | 1 |
| Hueber, EF | 1 |
3 reviews available for reserpine and Hypokalemia
| Article | Year |
|---|---|
[New trends in the treatment of moderate arterial hypertension].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood P | 1986 |
Present day management of hypertension.
Topics: Acute Kidney Injury; Angiography; Antihypertensive Agents; Aortic Aneurysm; Diet, Sodium-Restricted; | 1974 |
Antihypertensive action of benzothiadiazines.
Topics: Benzothiadiazines; Chlorothiazide; Guanethidine; Humans; Hyperglycemia; Hypertension; Hypokalemia; M | 1968 |
2 trials available for reserpine and Hypokalemia
| Article | Year |
|---|---|
Changes in serum potassium mediate thiazide-induced diabetes.
Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidone; Diabetes Mellitus, Type 2; | 2008 |
Effects of treatment on morbidity in hypertension. 3. Influence of age, diastolic pressure, and prior cardiovascular disease; further analysis of side effects.
Topics: Adult; Age Factors; Aged; Aneurysm; Atrial Fibrillation; Blood Glucose; Blood Pressure; Cerebrovascu | 1972 |
11 other studies available for reserpine and Hypokalemia
| Article | Year |
|---|---|
[ACUTE MALIGNANT HYPERTENSION WITH SECONDARY ALDOSTERONISM. A CASE IN A 31-YEAR-OLD MAN WITH CONGENITAL UNILATERAL RENAL HYPOPLASIA].
Topics: Alkalosis; Antihypertensive Agents; Blood Chemical Analysis; Congenital Abnormalities; Guanethidine; | 1964 |
Hypokalemia during the treatment of arterial hypertension with diuretics.
Topics: Adult; Aged; Bicarbonates; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertens | 1980 |
Complications of antihypertensive therapy.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Female; Guanethidine; Humans; Hydr | 1981 |
Paroxysmal atrial fibrillation with asystole and syncope: report of a case of sinus node dysfunction with hypokalemia and hypertension.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Heart Arrest; Humans; Hypertension; Hypokalemia; Male; Mi | 1976 |
[Preoperative correction of volemic disorders in thyrotoxicosis].
Topics: Albumins; Blood Volume; Diuresis; Glucose Solution, Hypertonic; Humans; Hydrocortisone; Hypernatremi | 1976 |
Angiotensin converting enzyme inhibition in clinical practice. Choice of initial treatment.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Captopril; Cholesterol; Diu | 1985 |
Thyrotoxic periodic paralysis.
Topics: Adult; Antithyroid Agents; Electromyography; Humans; Hyperthyroidism; Hypokalemia; Male; Methimazole | 1969 |
A new combination of hypotensive drugs (reserpine, dihydralazine, furosemide and triamterene) for the treatment of arterial hypertension without risk of hypopotassaemia.
Topics: Antihypertensive Agents; Arteries; Furosemide; Hypokalemia; Pyridazines; Reserpine; Triamterene | 1969 |
The role of catecholamines in producing arrhythmias.
Topics: Anesthetics; Antidepressive Agents; Arrhythmias, Cardiac; Atropine; Catecholamines; Digitalis Glycos | 1971 |
[Experiences gained with a new antihypertonic drug (Briserin)].
Topics: Amides; Clopamide; Diuretics; Ergot Alkaloids; Hypertension; Hypertension, Renal; Hypokalemia; Piper | 1968 |
[On combined therapy of hypertension and heart insufficiency. Advantages and disadvantages].
Topics: Arrhythmias, Cardiac; Chlorthalidone; Digitoxin; Drug Synergism; Heart Function Tests; Humans; Hyper | 1966 |