reserpine has been researched along with Hyperactivity, Motor in 24 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tetrabenazine (TBZ) is a monoamine-depleting agent initially studied in the 1950s and currently approved by the US Food and Drug Administration for the treatment of chorea in Huntington's disease." | 6.46 | Tetrabenazine, a monoamine-depleting drug used in the treatment of hyperkinetic movement disorders. ( Guay, DR, 2010) |
| "Tetrabenazine (TBZ) is a monoamine-depleting agent initially studied in the 1950s and currently approved by the US Food and Drug Administration for the treatment of chorea in Huntington's disease." | 2.46 | Tetrabenazine, a monoamine-depleting drug used in the treatment of hyperkinetic movement disorders. ( Guay, DR, 2010) |
| "l-DOPA (125 mg/kg) elicits hyperkinesia in reserpine-treated rats, the vertical component of which (rearing) is attenuated by agents with antidyskinetic actions in MPTP-lesioned primates and Parkinson's disease (PD) [Johnston, T." | 1.33 | Actions at sites other than D(3) receptors mediate the effects of BP897 on l-DOPA-induced hyperactivity in monoamine-depleted rats. ( Brotchie, JM; Millan, MJ; Visanji, NP, 2006) |
| "Pretreatment with reserpine (0." | 1.26 | Effects of reserpine and amphetamine on the development of hyperactivity in maternally deprived rat pups. ( Hofer, MA, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (75.00) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 2 (8.33) | 29.6817 |
| 2010's | 2 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alachkar, A | 1 |
| Brotchie, JM | 3 |
| Jones, OT | 1 |
| Guay, DR | 1 |
| Segovia, G | 1 |
| Mora, F | 1 |
| Crossman, AR | 1 |
| HORENSTEIN, S | 2 |
| GERSTENBRAND, F | 3 |
| WEINGARTEN, K | 2 |
| DE NEGRI, M | 1 |
| GRILLO, V | 1 |
| PROSENZ, P | 1 |
| Visanji, NP | 1 |
| Millan, MJ | 1 |
| Jancsár, SM | 1 |
| Leonard, BE | 1 |
| Cools, AR | 1 |
| van Rossum, JM | 1 |
| Arnt, J | 1 |
| Hofer, MA | 1 |
| Nakajima, H | 1 |
| Shigehara, R | 1 |
| Shimada, M | 1 |
| Totsuka, Y | 1 |
| Arai, E | 1 |
| Kobayashi, M | 1 |
| Maj, J | 1 |
| Rogóz, Z | 1 |
| Skuza, G | 1 |
| Krylov, SS | 1 |
| Petrov, AN | 1 |
| Pososinovikova, MP | 1 |
| Pan, SY | 1 |
| Renwart, N | 1 |
| Frances, H | 1 |
| Simon, P | 1 |
| Grahame-Smith, DG | 1 |
| Benkert, O | 1 |
| Köhler, B | 1 |
| Williams, BJ | 1 |
| Pirch, JH | 1 |
| Cheah, JS | 1 |
| Kaeser, HE | 1 |
| Ferel, D | 1 |
| Wurmser, P | 1 |
| Fog, R | 1 |
| Pakkenberg, H | 1 |
2 reviews available for reserpine and Hyperactivity, Motor
| Article | Year |
|---|---|
Tetrabenazine, a monoamine-depleting drug used in the treatment of hyperkinetic movement disorders.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Cytochrome P | 2010 |
Multiple receptors for brain dopamine in behavior regulation: concept of dopamine-E and dopamine-I receptors.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Behavior, Animal; Brain; Cats; Corpus Striatum; Dextroamphe | 1980 |
1 trial available for reserpine and Hyperactivity, Motor
| Article | Year |
|---|---|
A double-blind trial of reserpine in small doses as an adjunct in the treatment of hyperthyroidism.
Topics: Adult; Clinical Trials as Topic; Female; Humans; Hyperkinesis; Hyperthyroidism; Male; Middle Aged; P | 1972 |
21 other studies available for reserpine and Hyperactivity, Motor
| Article | Year |
|---|---|
Locomotor response to L-DOPA in reserpine-treated rats following central inhibition of aromatic L-amino acid decarboxylase: further evidence for non-dopaminergic actions of L-DOPA and its metabolites.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Aromatic Amino Acid Decarboxyla | 2010 |
Effects of CB1 cannabinoid receptor modulating compounds on the hyperkinesia induced by high-dose levodopa in the reserpine-treated rat model of Parkinson's disease.
Topics: Adrenergic Uptake Inhibitors; Animals; Antiparkinson Agents; Behavior, Animal; Cannabinoid Receptor | 2003 |
Reserpine and chlorpromazine in hyperactive mental defectives.
Topics: Chlorpromazine; Diet, Reducing; Hyperkinesis; Intellectual Disability; Reserpine | 1957 |
Reserpine and chlorpromazine in hyperactive mental defectives.
Topics: Chlorpromazine; Diet, Reducing; Hyperkinesis; Intellectual Disability; Reserpine | 1957 |
Reserpine and chlorpromazine in hyperactive mental defectives.
Topics: Chlorpromazine; Diet, Reducing; Hyperkinesis; Intellectual Disability; Reserpine | 1957 |
Reserpine and chlorpromazine in hyperactive mental defectives.
Topics: Chlorpromazine; Diet, Reducing; Hyperkinesis; Intellectual Disability; Reserpine | 1957 |
[Serpasil treatment of extrapyramidal hyperkinesia].
Topics: Humans; Hyperkinesis; Movement Disorders; Reserpine | 1956 |
[Serpasil treatment of extrapyramidal hyperkinesia].
Topics: Humans; Hyperkinesis; Movement Disorders; Reserpine | 1956 |
[Serpasil treatment of extrapyramidal hyperkinesia].
Topics: Humans; Hyperkinesis; Movement Disorders; Reserpine | 1956 |
[Serpasil treatment of extrapyramidal hyperkinesia].
Topics: Humans; Hyperkinesis; Movement Disorders; Reserpine | 1956 |
[Reserpine treatment of certain forms of hyperkinesia in children; report on 20 cases].
Topics: Child; Humans; Hyperkinesis; Infant; Movement Disorders; Reserpine | 1957 |
[ON THE TREATMENT OF EXTRAPYRAMIDAL HYPERKINESIA WITH A NEW RESERPINE DERIVATIVE (RESEPINE ASCORBINATE)].
Topics: Ascorbic Acid; Athetosis; Chorea; Encephalitis; Extrapyramidal Tracts; Humans; Hyperkinesis; Movemen | 1963 |
Actions at sites other than D(3) receptors mediate the effects of BP897 on l-DOPA-induced hyperactivity in monoamine-depleted rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Biogenic Monoamines; Dopamine D2 Receptor A | 2006 |
Behavioural and neurochemical interactions between chronic reserpine and chronic antidepressants. A possible model for the detection of atypical antidepressants.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Bridged Bicyclo Compounds; Bridged-Ring Com | 1983 |
Hyperactivity following injection of a glutamate agonist and 6,7-ADTN into rat nucleus accumbens and its inhibition by THIP.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Humans; Hyperkinesis; I | 1981 |
Effects of reserpine and amphetamine on the development of hyperactivity in maternally deprived rat pups.
Topics: Animals; Body Temperature; Dextroamphetamine; Dose-Response Relationship, Drug; Heart Rate; Humans; | 1980 |
[Effect of alpha-methyl-para-tyrosine on "methamphetamine-induced sterotype and hypermotility" of reserpinized rats (author's transl)].
Topics: alpha-Methyltyrosine; Animals; Humans; Hyperkinesis; Male; Methamphetamine; Methyltyrosines; Rats; R | 1981 |
The anticataleptic effect of 7-OH-DPAT: are dopamine D3 receptors involved?
Topics: Animals; Antipsychotic Agents; Brain Chemistry; Catalepsy; Dextroamphetamine; Dopamine Agents; Dopam | 1999 |
[The effect of nicotine on the concentration of noradrenaline in the brains of rats].
Topics: Amphetamine; Animals; Brain Chemistry; Depression, Chemical; Drug Interactions; Humans; Hyperkinesis | 1975 |
Acetylcholine contents and muscarinic receptor levels in frontal cortex, corpus striatum, and hippocampus of reserpinized rats and mice.
Topics: Acetylcholine; Animals; Brain; Corpus Striatum; Frontal Lobe; Hippocampus; Hyperkinesis; Male; Mice; | 1992 |
The calcium entry blockers: anti-manic drugs?
Topics: Amphetamines; Animals; Bipolar Disorder; Calcium Channel Blockers; Diltiazem; Hyperkinesis; Male; Mi | 1986 |
Editorial: Facial hyperkinesis.
Topics: Animals; Dihydroxyphenylalanine; Dopamine; Facial Muscles; Haplorhini; Humans; Hyperkinesis; Phenoth | 1974 |
Studies in vivo on the relationship between brain tryptophan, brain 5-HT synthesis and hyperactivity in rats treated with a monoamine oxidase inhibitor and L-tryptophan.
Topics: 5-Hydroxytryptophan; Amines; Amino Acids; Animals; Brain Chemistry; Carboxy-Lyases; Dopamine; Fenclo | 1971 |
Intrahypothalamic and intrastriatal dopamine and norepinephrine injections in relation to motor hyperactivity in rats.
Topics: Animals; Brain; Corpus Striatum; Dopamine; Fenclonine; Humans; Hyperkinesis; Hypothalamus; Injection | 1972 |
Correlation between brain adenyl cyclase activity and spontaneous motor activity in rats after chronic reserpine treatment.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Brain; Brain Chemistry; Carbon Radioisotopes; Ca | 1974 |
[Treatment of Parkinson's syndrome with L-dopa].
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Antihypertensive Agents; Barbiturates; | 1970 |
Intracerebral lesions causing stereotyped behaviour in rats.
Topics: Amphetamine; Animals; Basal Ganglia; Behavior, Animal; Brain Injuries; Catalepsy; Catheterization; D | 1971 |