Page last updated: 2024-11-06

reserpine and Experimental Neoplasms

reserpine has been researched along with Experimental Neoplasms in 27 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Research Excerpts

ExcerptRelevanceReference
"Reserpine treatment decreased the growth of both tumors, whether unseparated or tumor-cell-enriched, and whether injected into the foot or the flank."1.26I. Tumor growth in mice with depressed capacity to mount inflammatory responses: possible role of macrophages. ( Hopper, KE; Nelson, DS; Nelson, M, 1981)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199026 (96.30)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Lu, Z1
Ortiz, A1
Verginadis, II1
Peck, AR1
Zahedi, F1
Cho, C1
Yu, P1
DeRita, RM1
Zhang, H1
Kubanoff, R1
Sun, Y1
Yaspan, AT1
Krespan, E1
Beiting, DP1
Radaelli, E1
Ryeom, SW1
Diehl, JA1
Rui, H1
Koumenis, C1
Fuchs, SY1
BELKIN, M2
HARDY, WG2
WEST, WL1
BAIRD, GM1
STEWARD, JD1
PRADHAN, SN1
DOMENJOZ, R1
SCHELLENBERG, H1
WILLHEIM, R1
O'MALLEY, BB1
FLUSS, P1
DICKSON, J1
AUBER, M1
LACASSAGNE, A3
HURST, L1
CARLINI, GR1
FISCHER, GA1
GIARMAN, NJ1
Burdman, JA1
Calabrese, MT1
MacLeod, RM2
Nelson, M1
Nelson, DS1
Hopper, KE1
Lapin, V3
Apffel, CA1
Walker, JE1
Issarescu, S1
Byar, DP1
Blackard, CE1
Greene, LA1
Rein, G1
Rotman, A1
Daly, JW1
Creveling, CR1
Breakefield, XO1
Bell, SC1
Wei, PH1
Mückter, H1
Moré, E1
Hilz, H1
Jarmers, G1
Saunders, RN1
Miya, TS1
Bousquet, WF1
Hermetet, JC1
Ciesielski-Treska, J1
Mandel, P1
Kozuka, S1
Fontham, EH1
Lehmeyer, JE1

Reviews

1 review available for reserpine and Experimental Neoplasms

ArticleYear
Reserpine.
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 1980, Volume: 24

    Topics: Animals; Chemical Phenomena; Chemistry; Female; Humans; Male; Mice; Neoplasms, Experimental; Rats; R

1980

Other Studies

26 other studies available for reserpine and Experimental Neoplasms

ArticleYear
Regulation of intercellular biomolecule transfer-driven tumor angiogenesis and responses to anticancer therapies.
    The Journal of clinical investigation, 2021, 05-17, Volume: 131, Issue:10

    Topics: Animals; Endothelial Cells; Gene Knockdown Techniques; HCT116 Cells; Humans; Mice; Mice, Knockout; N

2021
Effect of reserpine and chlorpromazine on sarcoma 37.
    Science (New York, N.Y.), 1957, Feb-08, Volume: 125, Issue:3241

    Topics: Animals; Chlorpromazine; Neoplasms, Experimental; Reserpine; Sarcoma 37; Sarcoma, Experimental

1957
Effect of reserpine and chlorpromazine on sarcoma 37.
    Science (New York, N.Y.), 1957, Feb-08, Volume: 125, Issue:3241

    Topics: Animals; Chlorpromazine; Neoplasms, Experimental; Reserpine; Sarcoma 37; Sarcoma, Experimental

1957
Effect of reserpine and chlorpromazine on sarcoma 37.
    Science (New York, N.Y.), 1957, Feb-08, Volume: 125, Issue:3241

    Topics: Animals; Chlorpromazine; Neoplasms, Experimental; Reserpine; Sarcoma 37; Sarcoma, Experimental

1957
Effect of reserpine and chlorpromazine on sarcoma 37.
    Science (New York, N.Y.), 1957, Feb-08, Volume: 125, Issue:3241

    Topics: Animals; Chlorpromazine; Neoplasms, Experimental; Reserpine; Sarcoma 37; Sarcoma, Experimental

1957
Some studies on the anti-tumor effect of reserpine in mice.
    The Journal of pharmacology and experimental therapeutics, 1961, Volume: 131

    Topics: Animals; Antineoplastic Agents; Mice; Neoplasms; Neoplasms, Experimental; Reserpine

1961
[Pharmacological studies on 5-hydroxytryptamine metabolism in mastocytoma].
    Schweizerische medizinische Wochenschrift, 1962, Sep-29, Volume: 92

    Topics: Chlorpromazine; Dihydroxyphenylalanine; Imipramine; Iproniazid; Isocarboxazid; Mastocytoma; Mastocyt

1962
FURTHER STUDIES CONCERNING CARCINOLYSIS.
    Experimental medicine and surgery, 1963, Volume: 21

    Topics: Animals; Antineoplastic Agents; Blood; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Mice; Neoplasms

1963
[INFLUENCE OF SIMULTANEOUS ADMINISTRATION OF RESERPINE AND A CORTICOID ON CARCINOGENESIS OF RAT LIVER BY P-DIMETHYLAMINOAZOBENZENE (DAB)].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1963, Sep-02, Volume: 257

    Topics: Adenoma, Bile Duct; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinogenesis; Chemical and Drug

1963
DIFFERENCES IN CHARACTERISTICS OF RELEASE OF SEROTONIN FROM NEOPLASTIC MAST CELLS IN CULTURE BY RESERPINE AND CHLORPROMAZINE.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 146

    Topics: Chlorpromazine; Mast Cells; Metabolism; Monoamine Oxidase Inhibitors; Neoplasms; Neoplasms, Experime

1964
[RELATIONS BETWEEN THE TUMOR AND ORGANISM. THE ROLE OF THE HYPOTHALAMUS].
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Chlorpromazine; Gold; Hypothalamus; Neoplasms; Neoplasms, Experimental; Neurophysiology; Pharmacolog

1964
Hyperprolactinaemia and DNA synthesis in the pituitary gland of the rat.
    The Journal of endocrinology, 1983, Volume: 97, Issue:1

    Topics: alpha-Methyltyrosine; Animals; DNA; Female; Lisuride; Methyltyrosines; Neoplasms, Experimental; Pitu

1983
I. Tumor growth in mice with depressed capacity to mount inflammatory responses: possible role of macrophages.
    The American journal of pathology, 1981, Volume: 104, Issue:2

    Topics: Animals; Blood Cell Count; Blood Sedimentation; Corticosterone; Cyclophosphamide; Female; Fibrosarco

1981
Effects of reserpine on the incidence of 9,10-dimethyl-1,2-benzanthracene-induced tumors in pinealectomised and thymectomised rats.
    Oncology, 1978, Volume: 35, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Immunosuppression Therapy; Leukemia, Experimental

1978
[Effect of reserpine on the formation of 9,10-dimethyl-1,2-benzanthracene induced tumors in pinealectomized and thymectomized rats].
    Onkologie, 1978, Volume: 1, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Leukemia, Experimental; Neoplasms, Experimental; Pineal G

1978
Pineal influences on tumor.
    Progress in brain research, 1979, Volume: 52

    Topics: Animals; Animals, Newborn; Carcinogens; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental

1979
Tumor rejection in experimental animals treated with radioprotective thiols.
    Cancer research, 1975, Volume: 35, Issue:2

    Topics: Animals; beta-Aminoethyl Isothiourea; Carcinoma, Krebs 2; Cystamine; Cysteamine; Cysteine; Diamines;

1975
Letters: Rserpine and prostatic cancer.
    Urology, 1975, Volume: 5, Issue:1

    Topics: Animals; Breast Neoplasms; Carcinoma 256, Walker; Cell Transformation, Neoplastic; Dextrans; Drug Ev

1975
Reserpine: no changes advised for now.
    JAMA, 1979, Jul-20, Volume: 242, Issue:3

    Topics: Animals; Drug Evaluation, Preclinical; Humans; Mice; Neoplasms, Experimental; Rats; Reserpine; Unite

1979
Release of (3H)norepinephrine from a clonal line of pheochromocytoma cells (PC12) by nicotinic cholinergic stimulation.
    Brain research, 1977, Dec-23, Volume: 138, Issue:3

    Topics: Animals; Atropine; Calcium; Clone Cells; Dimethylphenylpiperazinium Iodide; Dose-Response Relationsh

1977
Uptake and binding of dopamine and 6-hydroxydopamine in murine neuroblastoma and fibroblast cells.
    Biochemical pharmacology, 1976, Feb-15, Volume: 25, Issue:4

    Topics: Animals; Cell Line; Dopamine; Electrophoresis, Polyacrylamide Gel; Hydroxydopamines; L Cells; Mice;

1976
Syntheses of heterocylic fused thiazole acetic acids. 2.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:4

    Topics: Acetates; Animals; Antidepressive Agents; Antineoplastic Agents; Antitubercular Agents; Bridged-Ring

1976
[Thalidomide and cancer].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:2

    Topics: Animals; Antineoplastic Agents; Benz(a)Anthracenes; Chlormadinone Acetate; Chlorpromazine; Cyclophos

1966
[Stimulation of tumor growths by anesthesia].
    Zeitschrift fur Krebsforschung, 1967, Volume: 70, Issue:2

    Topics: Adrenalectomy; Anesthesia; Anesthetics; Animals; Carcinogens; Carcinoma, Ehrlich Tumor; Cell Differe

1967
[Contrary to reserpine, yohimbine does not alter rat liver chemical carcinogenesis].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1970, Feb-02, Volume: 207, Issue:5

    Topics: Animals; Diet; Drug Synergism; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; p-Dimet

1970
Stimulation of DOPA14C incorporation into melanoma tissue by chlorpromazine and reserpine.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:2

    Topics: Animals; Carbon Isotopes; Catechol Oxidase; Chlorpromazine; Dihydroxyphenylalanine; In Vitro Techniq

1970
Cytochemical demonstration of catecholamines and acetylcholinesterase activity in neuroblastoma cells in culture.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1972, Volume: 20, Issue:2

    Topics: Acetylcholinesterase; Animals; Catecholamines; Cell Line; Cells, Cultured; Fluorescence; Formaldehyd

1972
Inhibiting effect of reserpine and female sensitivity in hepatic tumor induction with 2,7-diacetamidofluorene in SMA-Ms strain mice.
    Cancer research, 1970, Volume: 30, Issue:5

    Topics: Amides; Animals; Body Weight; Castration; Estradiol; Female; Fluorenes; Hyperplasia; Liver; Liver Ne

1970
Prolactin and growth hormone production as influenced by catecholamines and agents that affect brain catecholamines.
    Neuroendocrinology, 1970, Volume: 6, Issue:5

    Topics: Animals; Catecholamines; Depression, Chemical; Dopamine; Female; Growth Hormone; Guanethidine; In Vi

1970