reserpine has been researched along with Encephalopathy, Toxic in 4 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Sea urchins use neurotransmitters as embryonic growth regulatory signals, so that adverse effects on neural substrates for mammalian brain development can be studied in this simple organism." | 1.34 | The sea urchin embryo, an invertebrate model for mammalian developmental neurotoxicity, reveals multiple neurotransmitter mechanisms for effects of chlorpyrifos: therapeutic interventions and a comparison with the monoamine depleter, reserpine. ( Bezuglov, VV; Buznikov, GA; Lauder, JM; Milosević, I; Nikitina, LA; Rakić, LM; Slotkin, TA, 2007) |
| " To determine if the vesicular pool of DA was essential for the expression of METH-induced DA neurotoxicity, reserpine (3 mg/kg, given iintraperitoneally 24-26 h prior to METH) was given prior to a toxic dose regimen of METH." | 1.31 | Evidence against an essential role of endogenous brain dopamine in methamphetamine-induced dopaminergic neurotoxicity. ( Callahan, BT; McCann, UD; Ricaurte, GA; Yuan, J, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, S | 1 |
| Duan, M | 1 |
| Guan, K | 1 |
| Zhou, X | 1 |
| Zheng, M | 1 |
| Shi, X | 1 |
| Ye, M | 1 |
| Guan, W | 1 |
| Kuver, A | 1 |
| Huang, M | 1 |
| Liu, Y | 1 |
| Dai, K | 1 |
| Li, X | 1 |
| Thomas, DM | 1 |
| Francescutti-Verbeem, DM | 1 |
| Kuhn, DM | 1 |
| Buznikov, GA | 1 |
| Nikitina, LA | 1 |
| Rakić, LM | 1 |
| Milosević, I | 1 |
| Bezuglov, VV | 1 |
| Lauder, JM | 1 |
| Slotkin, TA | 1 |
| Yuan, J | 1 |
| Callahan, BT | 1 |
| McCann, UD | 1 |
| Ricaurte, GA | 1 |
4 other studies available for reserpine and Encephalopathy, Toxic
| Article | Year |
|---|---|
Developmental neurotoxicity of reserpine exposure in zebrafish larvae (Danio rerio).
Topics: Animals; Biogenic Monoamines; Dopaminergic Neurons; Embryo, Nonmammalian; Gene Expression Regulation | 2019 |
Increases in cytoplasmic dopamine compromise the normal resistance of the nucleus accumbens to methamphetamine neurotoxicity.
Topics: Animals; Clorgyline; Cytosol; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Plasma Mem | 2009 |
The sea urchin embryo, an invertebrate model for mammalian developmental neurotoxicity, reveals multiple neurotransmitter mechanisms for effects of chlorpyrifos: therapeutic interventions and a comparison with the monoamine depleter, reserpine.
Topics: Adrenergic Uptake Inhibitors; Animals; Chlorpyrifos; Disease Models, Animal; Dose-Response Relations | 2007 |
Evidence against an essential role of endogenous brain dopamine in methamphetamine-induced dopaminergic neurotoxicity.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Body Temperature; Brain Chemistry; Cy | 2001 |