reserpine has been researched along with EHS Tumor in 7 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diethylaminoreserpine (DL-152), an inhibitor of cyclic AMP phosphodiesterase, has been shown to kill clonogenic cells of the KHT fibrosarcoma when the drug is given intraperitoneally to the tumour-bearing mouse." | 3.66 | Toxicity to tumour cells of diethylaminoreserpine. ( Lehnert, S, 1980) |
| " Hypoxic cells were detectable in 10-day-old lung tumors, a time at which the tumors were still resistant to the toxic effects of DL-152." | 1.26 | Toxicity of diethylaminoreserpine to a transplantable tumor: the significance of the presence of hypoxic cells. ( Lehnert, S, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BELKIN, M | 2 |
| HARDY, WG | 2 |
| Lehnert, S | 3 |
| Fisher, G | 1 |
| Methot, G | 1 |
| Nelson, M | 1 |
| Nelson, DS | 1 |
| Apffel, CA | 1 |
| Walker, JE | 1 |
| Issarescu, S | 1 |
| Bordiushkov, IuH | 1 |
7 other studies available for reserpine and EHS Tumor
| Article | Year |
|---|---|
Effect of reserpine and chlorpromazine on sarcoma 37.
Topics: Animals; Chlorpromazine; Neoplasms, Experimental; Reserpine; Sarcoma 37; Sarcoma, Experimental | 1957 |
Effect of reserpine and chlorpromazine on sarcoma 37.
Topics: Animals; Chlorpromazine; Neoplasms, Experimental; Reserpine; Sarcoma 37; Sarcoma, Experimental | 1957 |
Effect of reserpine and chlorpromazine on sarcoma 37.
Topics: Animals; Chlorpromazine; Neoplasms, Experimental; Reserpine; Sarcoma 37; Sarcoma, Experimental | 1957 |
Effect of reserpine and chlorpromazine on sarcoma 37.
Topics: Animals; Chlorpromazine; Neoplasms, Experimental; Reserpine; Sarcoma 37; Sarcoma, Experimental | 1957 |
Toxicity to tumour cells of diethylaminoreserpine.
Topics: Animals; Cell Survival; Clone Cells; Female; Fibrosarcoma; Male; Mice; Mice, Inbred C3H; Reserpine; | 1980 |
Radioprotection of normal and malignant tissue in the mouse by diethylaminoreserpine.
Topics: Adenocarcinoma; Animals; Antihypertensive Agents; Cell Survival; Fibrosarcoma; Hematopoietic Stem Ce | 1981 |
Toxicity of diethylaminoreserpine to a transplantable tumor: the significance of the presence of hypoxic cells.
Topics: Anaerobiosis; Animals; Cell Line; Cell Survival; Clone Cells; Drug Evaluation, Preclinical; Kinetics | 1982 |
Macrophages and resistance to tumours: influence of agents affecting macrophages and delayed-type hypersensitivity on resistance to tumours inducing concomitant immunity.
Topics: Animals; Carrageenan; Depression, Chemical; Fibrosarcoma; Hypersensitivity, Delayed; Immunity; Immun | 1978 |
Tumor rejection in experimental animals treated with radioprotective thiols.
Topics: Animals; beta-Aminoethyl Isothiourea; Carcinoma, Krebs 2; Cystamine; Cysteamine; Cysteine; Diamines; | 1975 |
[On the inhibition of the growth of induced tumors by affecting the hypothalamus].
Topics: Animals; Benzopyrenes; Electric Stimulation; Hypothalamus; Niacinamide; Rats; Reserpine; Sarcoma, Ex | 1968 |