reserpine has been researched along with Diabetic Retinopathy in 2 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypertension is an important risk factor associated with development and progression of diabetic retinopathy (DR)." | 1.34 | Prevention of hypertension abrogates early inflammatory events in the retina of diabetic hypertensive rats. ( Biswas, SK; de Faria, JB; de Faria, JM; Pinto, CC; Silva, KC; Souza, DS, 2007) |
| "Perindopril was associated with significantly lower AER than lacidipine, whereas lacidipine was more potent in preventing increases in ocular AVC." | 1.29 | Organ specificity of antihypertensive therapy on ocular albumin vascular clearance and albuminuria in the hypertensive diabetic rat. ( Cooper, M; Gin, T; Jerums, G; Joon, TL; Panagiotopoulos, S; Taylor, H, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silva, KC | 1 |
| Pinto, CC | 1 |
| Biswas, SK | 1 |
| Souza, DS | 1 |
| de Faria, JB | 1 |
| de Faria, JM | 1 |
| Gin, T | 1 |
| Joon, TL | 1 |
| Panagiotopoulos, S | 1 |
| Cooper, M | 1 |
| Taylor, H | 1 |
| Jerums, G | 1 |
2 other studies available for reserpine and Diabetic Retinopathy
| Article | Year |
|---|---|
Prevention of hypertension abrogates early inflammatory events in the retina of diabetic hypertensive rats.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Diabetic Retinopathy; Drug C | 2007 |
Organ specificity of antihypertensive therapy on ocular albumin vascular clearance and albuminuria in the hypertensive diabetic rat.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Press | 1996 |