reserpine has been researched along with Dementia in 19 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Present study was designed to monitor the cognitive profile of the animals upon repeated administration of reserpine, so as to determine that whether these animals should be used as animal models of Parkinson's dementia." | 7.91 | Repeated treatment with a low dose of reserpine as a progressive model of Parkinson's dementia. ( Haleem, DJ; Ikram, H, 2019) |
| "Present study was designed to monitor the cognitive profile of the animals upon repeated administration of reserpine, so as to determine that whether these animals should be used as animal models of Parkinson's dementia." | 3.91 | Repeated treatment with a low dose of reserpine as a progressive model of Parkinson's dementia. ( Haleem, DJ; Ikram, H, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (84.21) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikram, H | 1 |
| Haleem, DJ | 1 |
| BLACKMAN, LH | 2 |
| GLENN, A | 2 |
| OLINGER, L | 2 |
| PROCTOR, RC | 1 |
| BAILEY, WH | 1 |
| MOREHOUSE, WG | 1 |
| ABD-EL-NABY, S | 1 |
| BARUCCI, M | 1 |
| MORI, F | 1 |
| BECKENSTEIN, N | 1 |
| PALMER, LS | 1 |
| ABSE, DW | 1 |
| DAHLSTROM, WG | 1 |
| KRONBERGEROVA, J | 1 |
| DERZSI, S | 1 |
| FENYVESI, T | 1 |
| THUILLIER, H | 1 |
| NAKAJIMA, H | 1 |
| GRANDJEAN, JL | 1 |
| LHULLIER, J | 1 |
| ROBINSON, DB | 1 |
| Hirai, S | 1 |
| Bovi, A | 1 |
| Frisone, L | 1 |
| Di Bari, M | 1 |
| Pahor, M | 1 |
| Franse, LV | 1 |
| Shorr, RI | 1 |
| Wan, JY | 1 |
| Ferrucci, L | 1 |
| Somes, GW | 1 |
| Applegate, WB | 1 |
| Snyder, BD | 1 |
| Harris, S | 1 |
| Wettstein, A | 1 |
| Bertolotti, P | 1 |
| Spaggiari, G | 1 |
| Fischer, E | 1 |
| Spatz, H | 1 |
| Heller, B | 1 |
| Reggiani, H | 1 |
1 review available for reserpine and Dementia
| Article | Year |
|---|---|
[Dementia induced by cardiokinetic and anti-hypertensive drugs].
Topics: Antihypertensive Agents; Cardiotonic Agents; Clonidine; Dementia; Digitoxin; Digoxin; Half-Life; Hum | 2004 |
1 trial available for reserpine and Dementia
| Article | Year |
|---|---|
Dementia and disability outcomes in large hypertension trials: lessons learned from the systolic hypertension in the elderly program (SHEP) trial.
Topics: Aged; Antihypertensive Agents; Atenolol; Bias; Chlorthalidone; Dementia; Disabled Persons; Double-Bl | 2001 |
17 other studies available for reserpine and Dementia
| Article | Year |
|---|---|
Repeated treatment with a low dose of reserpine as a progressive model of Parkinson's dementia.
Topics: Animals; Brain; Dementia; Disease Models, Animal; Dopamine; Hydroxyindoleacetic Acid; Male; Memory; | 2019 |
The use of vitarespital in the treatment of elderly psychotic patients.
Topics: Amphetamine; Amphetamines; Dementia; Humans; Mental Disorders; Psychotic Disorders; Reserpine; Vitam | 1958 |
An analeptic tranquilizer for senile psychoses; report of clinical and pharmacological studies of nicozol with reserpine.
Topics: Central Nervous System Stimulants; Dementia; Mental Disorders; Niacin; Pentylenetetrazole; Psychotic | 1958 |
Reserpine in the treatment of organic and senile psychosis.
Topics: Dementia; Mental Disorders; Psychosurgery; Psychotic Disorders; Reserpine | 1957 |
[Effects of reserpine combined with a psycho-analeptic drug on mental efficiency of the aged].
Topics: Aged; Arteriosclerosis; Central Nervous System Stimulants; Dementia; Mental Disorders; Methylphenida | 1957 |
The combination of tranquilizer, sympathomimetic drug and vitamins in the treatment of elderly psychotic patients.
Topics: Amphetamine; Amphetamines; Dementia; Humans; Hypnotics and Sedatives; Mental Disorders; Psychotic Di | 1958 |
Use of reserpine (rau-sed) in the treatment of the senile and cerebral arteriosclerotic psychotic.
Topics: Brain; Dementia; Humans; Mental Disorders; Psychotic Disorders; Reserpine | 1958 |
The value of chemotherapy in senile mental distrubances. Controlled comparison of chlorpromazine, reserpine-pipradrol, and opium.
Topics: Chlorpromazine; Dementia; Humans; Mental Disorders; Opium; Piperidines; Psychopharmacology; Psychoti | 1960 |
[CHANGES IN THE CLINICAL PICTURE OF ARTERIOSCLEROTIC AND SENILE DISEASES].
Topics: Antihypertensive Agents; Chlorpromazine; Dementia; Electroconvulsive Therapy; Geriatrics; Intracrani | 1963 |
HIREPINE IN PSYCHIATRY.
Topics: Catatonia; Chlorpromazine; Convulsive Therapy; Dementia; Depression; Electroconvulsive Therapy; Huma | 1964 |
[EXPERIMENTAL NEUROPHARMACOLOGY OF FACILITATION OF ELECTRICAL CONVULSIONS AS A BASIS FOR RESEARCH IN GERONTOLOGICAL PSYCHIATRY].
Topics: Central Nervous System Stimulants; Convulsive Therapy; Dementia; Electroconvulsive Therapy; Neuropha | 1964 |
Evaluation of certain drugs in geriatric patients: effects of chlorpromazine, reserpine, pentylenetetrazol U. S. P., and placebo on eighty-four female geriatric patients in a state hospital.
Topics: Chlorpromazine; Dementia; Female; Hospitals, State; Mental Disorders; Pentylenetetrazole; Psychotic | 1959 |
[The use of a reserpine derivative in the neuroses of the aged].
Topics: Aged; Anxiety Disorders; Dementia; Depression; Female; Humans; Hypochondriasis; Male; Middle Aged; R | 1967 |
Treatable aspects of the dementia syndrome.
Topics: Adjustment Disorders; Aged; Dementia; Diagnosis, Differential; Drug Interactions; Drug Therapy, Comb | 1976 |
[Remarks on the drug treatment of demented patients].
Topics: Aged; Alzheimer Disease; Antidepressive Agents; Antipsychotic Agents; Blood Glucose; Cerebrovascular | 1985 |
[Note on the use of dihydrogenated derivatives of ergotoxin (Hydergine) and their association with psychopharmacology in the treatment of aged neuropsychiatric patients].
Topics: Aged; Barbiturates; Butyrophenones; Dementia; Ergoloid Mesylates; Female; Humans; Imipramine; Male; | 1966 |
Phenethylamine content of human urine and rat brain, its alterations in pathological conditions and after drug administration.
Topics: Adjustment Disorders; Animals; Antidepressive Agents; Bipolar Disorder; Brain Chemistry; Dementia; D | 1972 |