reserpine has been researched along with Delayed Effects, Prenatal Exposure in 9 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
| Excerpt | Relevance | Reference |
|---|---|---|
| " More recently our laboratory has reported that prenatal exposure to haloperidol (HAL), a neuroleptic which binds to and blocks dopamine receptor sites in the adult brain, permanently stunts body and brain growth when that exposure extends throughout postimplantation pregnancy." | 3.69 | Prenatal neuroleptic exposure and growth stunting in the rat: an in vivo and in vitro examination of sensitive periods and possible mechanisms. ( Grafton, TF; Hansen, DK; Holson, RR; Webb, PJ, 1994) |
| "33 mg/kg reserpine was a reduction in maternal weight gained during both dosing periods." | 1.27 | Postnatal toxicity following prenatal reserpine exposure in rats: effects of dose and dosing schedule. ( Buelke-Sam, J; Kimmel, CA; Kimmel, GL; Nelson, CJ; Newport, GD; Slikker, W; Webb, PJ, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| van Onselen, R | 1 |
| Downing, TG | 1 |
| Menezes, EC | 1 |
| Santos, PR | 1 |
| Goes, TC | 1 |
| Carvalho, VCB | 1 |
| Teixeira-Silva, F | 1 |
| Stevens, HE | 1 |
| Badauê-Passos, DJ | 1 |
| Dörner, G | 1 |
| Slotkin, TA | 1 |
| Buelke-Sam, J | 1 |
| Kimmel, GL | 2 |
| Webb, PJ | 2 |
| Slikker, W | 1 |
| Newport, GD | 1 |
| Nelson, CJ | 1 |
| Kimmel, CA | 2 |
| Holson, RR | 1 |
| Grafton, TF | 1 |
| Hansen, DK | 1 |
| Bellavía, SL | 1 |
| Sanz, EG | 1 |
| Sereno, R | 1 |
| Vermouth, NT | 1 |
| Sullivan-Jones, P | 1 |
| Watanabe, T | 1 |
| Matsuhashi, K | 1 |
| Takayama, S | 1 |
2 reviews available for reserpine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Sex hormones and neurotransmitters as mediators for sexual differentiation of the brain.
Topics: Acetylcholinesterase; Androgens; Animals; Avoidance Learning; Brain; Castration; Disorders of Sex De | 1981 |
The cardiac-sympathetic axis as a teratological model.
Topics: Animals; Animals, Newborn; Catecholamines; Central Nervous System; Drug-Related Side Effects and Adv | 1983 |
7 other studies available for reserpine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Neonatal Reserpine Administration Produces Widespread Neuronal Losses and ⍺-Synuclein Inclusions in a Rat Model.
Topics: alpha-Synuclein; Animals; Brain; Female; Inclusion Bodies; Neurons; Pregnancy; Prenatal Exposure Del | 2021 |
Effects of a rat model of gestational hypothyroidism on forebrain dopaminergic, GABAergic, and serotonergic systems and related behaviors.
Topics: Amygdala; Animals; Anxiety; Anxiety Disorders; Disease Models, Animal; Dopamine; Dopaminergic Neuron | 2019 |
Postnatal toxicity following prenatal reserpine exposure in rats: effects of dose and dosing schedule.
Topics: Animals; Biogenic Amines; Body Weight; Dose-Response Relationship, Drug; Drug Administration Schedul | 1984 |
Prenatal neuroleptic exposure and growth stunting in the rat: an in vivo and in vitro examination of sensitive periods and possible mechanisms.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Benzazepines; Body Weight; Brain; Dopamine D2 R | 1994 |
Alpha-amylase circadian rhythm of young rat parotid gland: an endogenous rhythm with maternal coordination.
Topics: Aging; alpha-Amylases; alpha-Methyltyrosine; Animals; Circadian Rhythm; Female; Food Deprivation; Li | 1992 |
Prenatal reserpine exposure alters cardiovascular parameters in rat offspring.
Topics: Animals; Blood Pressure; Body Weight; Electrocardiography; Female; Heart Rate; Hemodynamics; Male; O | 1989 |
[Study on the postnatal neuro-behavioral development in rats treated prenatally with drugs acting on the autonomic nervous systems].
Topics: Animals; Atropine; Autonomic Agents; Central Nervous System Diseases; Chlorpromazine; Epinephrine; F | 1985 |