Page last updated: 2024-11-06

reserpine and Decerebrate Posturing

reserpine has been researched along with Decerebrate Posturing in 44 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Research Excerpts

ExcerptRelevanceReference
" Reserpinization shifted the (-)-norephedrine dose-response curve slightly to the right, indicating that only a minor portion of its activity is due to the release of stored endogenous catecholamines."1.27Adrenergic receptor subtype activation by (+)-, (-)- and (+/-)-norephedrine in the pithed rat. ( Maher, TJ; Moya-Huff, FA, 1987)
"Reserpine pretreatment led to smaller responses than prazosin plus rauwolscine."1.27Analysis of the alpha-adrenoceptor-mediated, and other, components in the sympathetic vasopressor responses of the pithed rat. ( Flavahan, NA; Grant, TL; Greig, J; McGrath, JC, 1985)
"Pretreatment with reserpine prevented the restoration of blood pressure by all drugs."1.27The effects of meptazinol in comparison with pentazocine, morphine and naloxone in a rat model of anaphylactic shock. ( Paciorek, PM; Todd, MH; Waterfall, JF, 1985)
"Pretreatment with reserpine reduced waking and spindle sleep while the synthesis inhibitors did not."1.26The role of endogenous catecholamines in the regulation of electrocortical activity in the encephale isole cat. ( Bradley, PB; Candy, JM; Keane, PE, 1976)
"Pretreatment with reserpine did not diminish the effect of morphine."1.26The effect of morphine on the activity evoked in ventrolateral tract axons of the cat spinal cord. ( Grossman, W; Jurna, I, 1976)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199038 (86.36)18.7374
1990's5 (11.36)18.2507
2000's1 (2.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
VALDECASAS, FG1
SALVA, JA1
VARMA, DR1
BENFEY, BG1
NAIMAN, JG1
WILLIAMS, HL1
SALMOIRAGHI, GC1
BLOOM, FE1
COSTA, E1
Valdivia, LF1
Centurión, D1
Perusquía, M1
Arulmani, U1
Saxena, PR2
Villalón, CM1
Herman, EH1
Barnes, CD1
Shin, YK1
Svinareff, P1
Schmitt-Jubeau, H1
Schmitt, H1
Bernthal, PJ1
Koss, MC2
Ruffolo, RR1
Goldberg, MR1
Morgan, EL1
Sedlácek, J1
De Neef, JH1
Jordaan, KM1
Porsius, AJ1
Matsushita, M1
Yonemori, F1
Furukawa, N1
Ohta, A1
Toide, K1
Uchida, I1
Iwata, K1
el Tahir, KE1
Ashour, MM1
al-Harbi, MM1
Hancock, DL1
Coupar, IM1
Smirnov, VM1
Keane, PE1
Candy, JM1
Bradley, PB1
Neal, H1
Bond, A1
Jurna, I1
Grossman, W1
Mergner, T1
Pompeiano, O1
Kobinger, W2
Pichler, L2
Lang, WJ1
Lambert, GA1
Rush, ML1
Saito, H1
Sato, M1
Pawlak, D1
Malinowska, B1
Buczko, W1
Maj, J1
Skuza, G1
Sowińska, H1
Nowak, G1
Moya-Huff, FA1
Maher, TJ1
Dhasmana, KM1
De Boer, HJ1
Banerjee, AK1
Flavahan, NA1
Grant, TL1
Greig, J1
McGrath, JC1
Latini, R1
Zuanetti, G1
Conforti, L1
Schwartz, PJ1
Lazzara, R1
Giuliani, S1
Maggi, CA1
Meli, A1
Paciorek, PM1
Todd, MH1
Waterfall, JF1
Kadzielawa, K1
Widy-Tyszkiewicz, E1
Flórez, J2
Delgado, G2
Armijo, JA2
Laurent, JP1
Cespuglio, R1
Jouvet, M1
Clarke, DE1
Leach, GD1
Hirano, H1
Inoue, Y1
Tanami, J1
Commissiong, JW1
Sedgwick, EM1
Katz, RL1
Kaverina, NV1
Bendikov, EA1
Rozonov, IuB1
Wang, SC1
Chiba, S1
Dixon, RE1
Ellaway, PH1
Hansen, SM1
Pascoe, JE1

Other Studies

44 other studies available for reserpine and Decerebrate Posturing

ArticleYear
Action of reserpine on the spinal cat.
    Archives internationales de pharmacodynamie et de therapie, 1962, Dec-01, Volume: 140

    Topics: Animals; Blood Pressure; Blood Pressure Determination; Cats; Decerebrate State; Felis; Monoamine Oxi

1962
ANTAGONISM OF RESERPINE-INDUCED SUBSENSITIVITY TO TYRAMINE BY METHYLDOPA.
    The Journal of pharmacology and experimental therapeutics, 1963, Volume: 141

    Topics: Antihypertensive Agents; Bretylium Compounds; Cats; Chlorpromazine; Decerebrate State; Guanethidine;

1963
EFFECTS OF DIPHENYLHYDANTOIN ON THE DURATION OF RESPIRATORY ACTIVITY DURING ANOXIA.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 145

    Topics: Anticonvulsants; Cats; Cell Respiration; Decerebrate State; Electroencephalography; Guinea Pigs; Hyp

1964
ADRENERGIC MECHANISMS IN RABBIT OLFACTORY BULB.
    The American journal of physiology, 1964, Volume: 207

    Topics: Adrenergic Agents; Atropine; Brain; Chlorisondamine; Decerebrate State; Dopamine; Electrophoresis; H

1964
Pharmacological analysis of the mechanisms involved in the tachycardic and vasopressor responses to the antimigraine agent, isometheptene, in pithed rats.
    Life sciences, 2004, May-14, Volume: 74, Issue:26

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Decerebrate Stat

2004
Observations of drug effects on a type of spinal motor activity.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 165, Issue:2

    Topics: Animals; Atropine; Chlorpromazine; Decerebrate State; Motor Neurons; Muscles; Pentobarbital; Phenoxy

1967
Effects of quipazine on blood pressure in pithed rats.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 264, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Decerebrate State; Female; Male; Methysergide

1983
Evidence for two distinct sympathoinhibitory bulbo-spinal systems.
    Neuropharmacology, 1984, Volume: 23, Issue:1

    Topics: alpha-Methyltyrosine; Animals; Blood Pressure; Brain Stem; Catecholamines; Cats; Decerebrate State;

1984
Interactions of epinephrine, norepinephrine, dopamine and their corresponding alpha-methyl-substituted derivatives with alpha and beta adrenoceptors in the pithed rat.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:3

    Topics: Animals; Blood Pressure; Decerebrate State; Deoxyepinephrine; Dopamine; Dose-Response Relationship,

1984
Development of spontaneous motility in chick embryos. Interaction of reserpine and apomorphine.
    Physiologia Bohemoslovaca, 1980, Volume: 29, Issue:1

    Topics: Animals; Apomorphine; Central Nervous System; Chick Embryo; Decerebrate State; Depression, Chemical;

1980
The effects of paraoxon on blood pressure in the anaesthetized and in the conscious rat.
    British journal of pharmacology, 1982, Volume: 77, Issue:2

    Topics: Acetylcholinesterase; Adrenalectomy; Anesthesia; Animals; Blood Pressure; Decerebrate State; Injecti

1982
Effects of the novel thyrotropin-releasing hormone analogue Na -((1S,2R)-2-methyl-4-oxocyclopentylcarbonyl)-L-histidyl-L-prol ina mide monohydrate on the central nervous system in mice and rats.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:8

    Topics: Animals; Body Temperature; Brain Concussion; Central Nervous System; Chlorpromazine; Consciousness;

1993
The cardiovascular actions of the volatile oil of the black seed (Nigella sativa) in rats: elucidation of the mechanism of action.
    General pharmacology, 1993, Volume: 24, Issue:5

    Topics: Animals; Atropine; Blood Pressure; Cyproheptadine; Decerebrate State; Heart Rate; Hemodynamics; Male

1993
Studies investigating the possible involvement of adenosine in the antisecretory action of morphine.
    General pharmacology, 1997, Volume: 28, Issue:5

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Decerebrate State; Female; Intestinal Mucosa;

1997
[Mechanism of acceleration of myocardial contractions caused by stimulation of vagus nerve ganglia in frogs].
    Biulleten' eksperimental'noi biologii i meditsiny, 1997, Volume: 124, Issue:7

    Topics: Animals; Atropine; Decerebrate State; Ganglionic Blockers; Hexamethonium Compounds; Medulla Oblongat

1997
The role of endogenous catecholamines in the regulation of electrocortical activity in the encephale isole cat.
    Electroencephalography and clinical neurophysiology, 1976, Volume: 41, Issue:6

    Topics: Animals; Arousal; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Catecholamines; Caudate Nucl

1976
Modification of PGO activity by specific uptake inhibitors fluoxetine, nisoxetine and LR5182.
    Neuropharmacology, 1979, Volume: 18, Issue:10

    Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Bri

1979
The effect of morphine on the activity evoked in ventrolateral tract axons of the cat spinal cord.
    Experimental brain research, 1976, Mar-15, Volume: 24, Issue:5

    Topics: Afferent Pathways; Animals; Axons; Brain Stem; Cold Temperature; Decerebrate State; Depression, Chem

1976
Single unit firing patterns in the vestibular nuclei related to saccadic eye movement in the decerebrate cat.
    Archives italiennes de biologie, 1978, Volume: 116, Issue:2

    Topics: Animals; Axons; Cats; Decerebrate State; Electromyography; Electrooculography; Eye Movements; Neuron

1978
The central modulatory effect of clonidine on the cardiodepressor reflex after suppression of synthesis and storage of noradrenaline.
    European journal of pharmacology, 1975, Volume: 30, Issue:1

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Pressure; Brain; Clonidine; Decerebrate

1975
The role of the central nervous system in the cardiovascular responses to yohimbine.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 217, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Central Nervous System; Decerebrate Sta

1975
[Mechanism of reversal of the blood pressure by ephedrine. (2)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1977, Volume: 73, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Platelets; Blood Pressure; Decerebrate State; Drug Synergism

1977
[Pharmacological studies of 4-ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone (M73101). (5) Action of M73101 on the central nervous system (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1979, Volume: 75, Issue:7

    Topics: Aminophylline; Animals; Anticonvulsants; Body Temperature; Catalepsy; Cats; Central Nervous System;

1979
Cardiovascular effects of acetaldehyde in pithed rats.
    Pharmacology, 1992, Volume: 45, Issue:2

    Topics: Acetaldehyde; Animals; Blood Pressure; Cardiovascular System; Decerebrate State; Heart Rate; Male; P

1992
Pharmacological properties of EXP 561, a potential antidepressant drug.
    Journal of neural transmission, 1987, Volume: 70, Issue:1-2

    Topics: Aggression; Amphetamine; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Blood Pressu

1987
Adrenergic receptor subtype activation by (+)-, (-)- and (+/-)-norephedrine in the pithed rat.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:2

    Topics: Animals; Blood Pressure; Cardiovascular System; Decerebrate State; Heart Rate; Isomerism; Male; Phen

1987
Analysis of the tachycardiac response to 5-hydroxytryptamine in the spinal guinea-pig.
    European journal of pharmacology, 1988, Jan-05, Volume: 145, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Decerebrate State; Female; Guinea Pigs; Heart Rate;

1988
Analysis of the alpha-adrenoceptor-mediated, and other, components in the sympathetic vasopressor responses of the pithed rat.
    British journal of pharmacology, 1985, Volume: 86, Issue:1

    Topics: Adenosine Triphosphate; Adrenalectomy; Animals; Blood Pressure; Decerebrate State; Electric Stimulat

1985
Demonstration of a different sensitivity to epinephrine in isolated and in vivo hearts.
    European journal of pharmacology, 1988, Oct-26, Volume: 156, Issue:1

    Topics: Animals; Decerebrate State; Epinephrine; Heart; In Vitro Techniques; Male; Rats; Rats, Inbred Strain

1988
Capsaicin-sensitive afferents in the rat urinary bladder activate a spinal sympathetic cardiovascular reflex.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:4

    Topics: Animals; Capsaicin; Decerebrate State; Electric Stimulation; Hemodynamics; Hexamethonium Compounds;

1988
The effects of meptazinol in comparison with pentazocine, morphine and naloxone in a rat model of anaphylactic shock.
    British journal of pharmacology, 1985, Volume: 84, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Decerebrate State; Electric Stimulation; Female; Hea

1985
Evidence for direct alpha-adrenoceptor stimulation of effector neurons in cardiovascular centers by clonidine.
    European journal of pharmacology, 1974, Volume: 27, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Pressure; Card

1974
The influence of various pharmacological agents on the desynchronization produced by DOPA in the cerveau isolé preparation.
    Electroencephalography and clinical neurophysiology, 1970, Volume: 28, Issue:3

    Topics: Animals; Cats; Chlorpromazine; Decerebrate State; Dihydroxyphenylalanine; Disulfiram; Electroencepha

1970
Adrenergic and serotonergic mechanisms in morphine-induced respiratory depression.
    Psychopharmacologia, 1972, Volume: 24, Issue:2

    Topics: Animals; Brain; Cats; Decerebrate State; Drug Synergism; Fenclonine; Morphine; Norepinephrine; Pargy

1972
Brain amines and development of acute tolerance to and dependence on morphine in the respiratory center of decerebrate cats.
    Neuropharmacology, 1973, Volume: 12, Issue:4

    Topics: Amines; Animals; Blood Pressure; Carbon Dioxide; Cats; Decerebrate State; Drug Tolerance; Fenclonine

1973
[Delineation of the ascendant pathway responsible for ponto-geniculo-occipital activity in the cat].
    Experientia, 1972, Oct-15, Volume: 28, Issue:10

    Topics: Animals; Cats; Cerebellar Nuclei; Chemoreceptor Cells; Decerebrate State; Electroencephalography; Ge

1972
The influence of bretylium on the interactions of infused sympathomi- metic amines and tyramine in the reserpine-treated pithed rat.
    British journal of pharmacology and chemotherapy, 1968, Volume: 32, Issue:2

    Topics: Animal Population Groups; Animals; Blood Pressure; Bretylium Compounds; Decerebrate State; Drug Syne

1968
[Studies on the mode of actions of carbon monoxide. 3. The central action of carbon monoxide].
    Nihon eiseigaku zasshi. Japanese journal of hygiene, 1971, Volume: 25, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Glucose; Blood Pressure; Carbon Monoxide; Carbon Monoxi

1971
A pharmacological study of the adrenergic mechanisms involved in the stretch reflex of the decerebrate rat.
    British journal of pharmacology, 1974, Volume: 50, Issue:3

    Topics: Animals; Benzyl Compounds; Catechols; Decerebrate State; Dihydroxyphenylalanine; Disulfides; Dopamin

1974
Neural factors affecting cardiac arrhythmias induced by halopropane.
    The Journal of pharmacology and experimental therapeutics, 1966, Volume: 152, Issue:1

    Topics: Adrenalectomy; Anesthetics; Animals; Arrhythmias, Cardiac; Atropine; Carbon Dioxide; Cats; Decerebra

1966
[The significance of central adrenergic processes in the mechanism of nitroglycerin action on the sympathetic tonus and vasomotor reflexes].
    Biulleten' eksperimental'noi biologii i meditsiny, 1969, Volume: 68, Issue:12

    Topics: Animals; Blood Pressure; Brain Chemistry; Cats; Decerebrate State; Electrocardiography; Fluorometry;

1969
Effects of reserpine on centrally and peripherally evoked nictitating membrane responses in the cat.
    The American journal of physiology, 1972, Volume: 222, Issue:4

    Topics: Animals; Cats; Decerebrate State; Electric Stimulation; Hypothalamus; Medulla Oblongata; Nictitating

1972
Inhibition of spinal polysynaptic reflex and augmentation of muscle contraction by 2-ethyl-4-ethylamino-6-methoxy-s-triazine.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:3

    Topics: Anesthesia; Animals; Atropine; Cats; Decerebrate State; Depression, Chemical; Electric Stimulation;

1969
Regularizing of fusimotor discharges by a descending 5-hydroxy-tryptaminergic pathway.
    The Journal of physiology, 1969, Volume: 202, Issue:2

    Topics: Animals; Decerebrate State; Lysergic Acid Diethylamide; Motor Neurons; Rabbits; Reserpine; Serotonin

1969