reserpine has been researched along with Cushing Syndrome in 25 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Cushing Syndrome: A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Direct effects of cyproheptadine, reserpine, synthetic ovine corticotropin-releasing factor (CRF), dexamethasone, and lysine-8-vasopressin (LVP) on the secretion of immunoreactive ACTH and beta-endorphin from the adenoma and the nonadenomatous tissue of patients with Cushing's disease were examined using a superfusion system." | 3.66 | Effects of cyproheptadine, reserpine, and synthetic corticotropin-releasing factor on pituitary glands from patients with Cushing's disease. ( Demura, H; Mouri, T; Sasaki, A; Shibasaki, T; Shizume, K; Suda, T; Tozawa, F, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (76.00) | 18.7374 |
| 1990's | 6 (24.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Neilson, GH | 1 |
| Slavnov, VN | 3 |
| Luchitskiĭ, EV | 2 |
| Komissarenko, IV | 3 |
| Markov, VV | 1 |
| Cheban, AK | 3 |
| Fehm, HL | 1 |
| Steck, R | 1 |
| Hohnloser, J | 1 |
| Voigt, KH | 1 |
| Pfeiffer, EF | 1 |
| Suda, T | 1 |
| Tozawa, F | 1 |
| Mouri, T | 1 |
| Sasaki, A | 1 |
| Shibasaki, T | 1 |
| Demura, H | 2 |
| Shizume, K | 1 |
| Iakovlev, AA | 1 |
| Rybakov, SI | 1 |
| Minamori, Y | 3 |
| Yasuda, K | 5 |
| Murayama, M | 4 |
| Morita, H | 2 |
| Yamakita, N | 4 |
| Miura, K | 9 |
| Mercado-Asis, LB | 3 |
| Leonard, BE | 1 |
| Yamada, Y | 1 |
| Nohara, Y | 1 |
| Hattori, T | 1 |
| Fujieda, K | 1 |
| Endo, M | 1 |
| Krieger, DT | 1 |
| Obara, T | 1 |
| Nakagawa, K | 1 |
| Keimatsu, M | 1 |
| Ito, Y | 1 |
| Kunita, H | 1 |
| Aida, M | 1 |
| Mihara, A | 1 |
| Kato, K | 1 |
| Ojima, M | 1 |
| Sasaki, M | 1 |
| Umeda, T | 1 |
| Iwaoka, T | 1 |
| Inoue, J | 1 |
| Sato, T | 2 |
| Hayashi, H | 1 |
| Torikai, T | 2 |
| Yoshinaga, K | 1 |
| Yoshida, H | 1 |
| Takeda, F | 1 |
| Kinouchi, T | 1 |
| Shimizu, N | 1 |
| Burch, WM | 1 |
| Iino, M | 1 |
| Demura, E | 1 |
| Sasaki, C | 1 |
| Batson, HM | 1 |
| Birchall, R | 1 |
| Weber, GF | 1 |
| Givens, JR | 1 |
| Camacho, A | 1 |
| Patterson, P | 1 |
4 reviews available for reserpine and Cushing Syndrome
| Article | Year |
|---|---|
Neurochemical and neuropharmacological aspects of depression.
Topics: Addison Disease; Adrenal Cortex Hormones; Amphetamines; Animals; Antidepressive Agents, Tricyclic; B | 1975 |
[Drug and radiotherapy of pituitary tumors].
Topics: Acromegaly; Adenoma; Adrenocorticotropic Hormone; Bromocriptine; Cushing Syndrome; Cyproheptadine; G | 1986 |
Cushing's disease. A review.
Topics: Adenoma; Adolescent; Adrenalectomy; Adult; Animals; Bromocriptine; Child; Combined Modality Therapy; | 1985 |
[Aspect of hormones and hypertension].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Catechol | 1969 |
1 trial available for reserpine and Cushing Syndrome
| Article | Year |
|---|---|
Effect of aminoglutethimide and reserpine on the human pituitary-adrenal axis: remission of a case of Cushing's disease.
Topics: 17-Hydroxycorticosteroids; Addison Disease; Adrenal Glands; Adult; Aldosterone; Aminoglutethimide; A | 1970 |
20 other studies available for reserpine and Cushing Syndrome
| Article | Year |
|---|---|
Hypertension: its management and investigation.
Topics: Aortic Coarctation; Cushing Syndrome; Electrocardiography; Female; Glomerulonephritis; Humans; Hyper | 1967 |
[Hypothalamo-pituitary-adrenal cortex system and the glucocorticoid kinetics in Cushing's syndrome treated with chlodithane and large doses of reserpine].
Topics: Adolescent; Adrenal Cortex; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Adult; Cushing | 1980 |
Influence of neuroactive drugs on corticosteroid feedback regulation of ACTH secretion in man.
Topics: Addison Disease; Adrenal Cortex Hormones; Adrenalectomy; Adrenocorticotropic Hormone; Cushing Syndro | 1983 |
Effects of cyproheptadine, reserpine, and synthetic corticotropin-releasing factor on pituitary glands from patients with Cushing's disease.
Topics: Adenoma; Adrenocorticotropic Hormone; beta-Endorphin; Corticotropin-Releasing Hormone; Cushing Syndr | 1983 |
[Renin-angiotensin-aldosterone system in patients with Itsenko-Cushing syndrome treated with chloditane and large doses of reserpine].
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Cushing Syndrome; Humans; Middle Aged; Mitotane; Ren | 1980 |
[Pancreatic alpha cell function in Itsenko-Cushing disease].
Topics: Adolescent; Adrenal Cortex Neoplasms; Adult; Blood Glucose; Cushing Syndrome; Glucagon; Humans; Hypo | 1982 |
Effects of reserpine treatment on pituitary-adrenocortical axis in patients with Cushing's disease.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Circadian Rhythm; Cushing Syndrome; Depression, Chemic | 1993 |
Long term follow-up of Cushing's disease treated with reserpine and pituitary irradiation followed by subtotal adrenalectomy.
Topics: Adolescent; Adrenalectomy; Adult; Combined Modality Therapy; Cushing Syndrome; Female; Follow-Up Stu | 1994 |
[A case of Cushing disease. An evaluation of endocrinology test for three years following hypothalamic-pituitary irradiation and reserpin administration (author's transl)].
Topics: Adrenocorticotropic Hormone; Child; Cushing Syndrome; Humans; Hydrocortisone; Male; Pituitary Irradi | 1979 |
Circadian pituitary adrenal rhythms.
Topics: 11-Hydroxycorticosteroids; Acetylcholine; Addison Disease; Adrenocorticotropic Hormone; Animals; Bra | 1975 |
[Cushing's disease].
Topics: Cushing Syndrome; Humans; Reserpine | 1979 |
[Two cases of Cushing's disease with sudden remission after an episode of hysteria or administration of reserpine-metyrapone (author's transl)].
Topics: Adolescent; Cushing Syndrome; Female; Humans; Hysteria; Metyrapone; Reserpine | 1976 |
Treatment of Cushing's disease with reserpine and pituitary irradiation.
Topics: Adrenalectomy; Adult; Cushing Syndrome; Female; Humans; Male; Pituitary Irradiation; Remission, Spon | 1975 |
Long term follow-up of Cushing's disease treated with reserpine and pituitary irradiation.
Topics: Adolescent; Adrenal Glands; Adult; Cushing Syndrome; Dose-Response Relationship, Radiation; Female; | 1992 |
Combined reserpine and pituitary irradiation therapy for Cushing's disease patients following unsuccessful transsphenoidal microsurgery.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenocorticotropic Hormone; Adult; Combined Modality Therapy; C | 1990 |
Reduction of pituitary tumor size with clinical and biochemical improvement with bromocriptine in a normoprolactinemic Cushing's disease.
Topics: Adrenocorticotropic Hormone; Adult; Bromocriptine; Cushing Syndrome; Dexamethasone; Drug Therapy, Co | 1990 |
[Cushing's disease--pathophysiology and treatment].
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Cortex Function Tests; Adult; Animals; Combined Modal | 1991 |
[Diagnosis and management of Cushing' syndrome based on our 28 cases, with special reference to combined therapy of 60Co irradiation of the hypothalamus and reserpine].
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Child; Cobalt Isotopes; C | 1970 |
Hypertension: current trends in diagnosis and treatment.
Topics: Aortic Coarctation; Azides; Cushing Syndrome; Ganglionic Blockers; Humans; Hydrazines; Hyperaldoster | 1967 |
[Study on a new treatment of Cushing's disease with pituitary irradiation and long-term administration of large-dose reserpine (author's transl)].
Topics: Adolescent; Adult; Cushing Syndrome; Female; Humans; Male; Middle Aged; Pituitary Irradiation; Reser | 1974 |