reserpine has been researched along with Cocaine Abuse in 5 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cocaine dependence is a public health problem characterised by recidivism and a host of medical and psychosocial complications." | 2.53 | Antipsychotic medications for cocaine dependence. ( Amato, L; Indave, BI; Minozzi, S; Pani, PP, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Susukida, R | 1 |
| Crum, RM | 1 |
| Hong, H | 1 |
| Stuart, EA | 1 |
| Mojtabai, R | 1 |
| Indave, BI | 1 |
| Minozzi, S | 1 |
| Pani, PP | 1 |
| Amato, L | 1 |
| Berger, SP | 1 |
| Winhusen, TM | 1 |
| Somoza, EC | 1 |
| Harrer, JM | 2 |
| Mezinskis, JP | 1 |
| Leiderman, DB | 2 |
| Montgomery, MA | 2 |
| Goldsmith, RJ | 2 |
| Bloch, DA | 2 |
| Singal, BM | 1 |
| Elkashef, A | 3 |
| Shoptaw, S | 1 |
| Montgomery, A | 1 |
| LoCastro, J | 1 |
| Vocci, F | 1 |
| Winhusen, T | 1 |
| Somoza, E | 1 |
| Sarid-Segal, O | 1 |
| Coleman, FS | 1 |
| Kahn, R | 1 |
| Osman, S | 1 |
| Mezinskis, J | 1 |
| Li, SH | 1 |
| Lewis, D | 1 |
| Afshar, M | 1 |
| Ciraulo, DA | 1 |
| Horn, P | 1 |
2 reviews available for reserpine and Cocaine Abuse
| Article | Year |
|---|---|
Comparing pharmacological treatments for cocaine dependence: Incorporation of methods for enhancing generalizability in meta-analytic studies.
Topics: Adult; Anti-Anxiety Agents; Buspirone; Central Nervous System Stimulants; Cocaine-Related Disorders; | 2018 |
Antipsychotic medications for cocaine dependence.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Cocaine-Related Disorders; Haloperidol; Humans; | 2016 |
3 trials available for reserpine and Cocaine Abuse
| Article | Year |
|---|---|
A medication screening trial evaluation of reserpine, gabapentin and lamotrigine pharmacotherapy of cocaine dependence.
Topics: Adult; Amines; Anticonvulsants; Antipsychotic Agents; Cocaine-Related Disorders; Cyclohexanecarboxyl | 2005 |
Cocaine Rapid Efficacy Screening Trial (CREST): a paradigm for the controlled evaluation of candidate medications for cocaine dependence.
Topics: Adolescent; Adult; Antipsychotic Agents; Cabergoline; Cocaine-Related Disorders; Dopamine Agonists; | 2005 |
A double-blind, placebo-controlled trial of reserpine for the treatment of cocaine dependence.
Topics: Administration, Intranasal; Adult; Antipsychotic Agents; Behavior Therapy; Cocaine; Cocaine-Related | 2007 |