reserpine has been researched along with Cerebral Hemorrhage in 16 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Cerebral Hemorrhage: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of antihypertensive drugs, such as nifedipine, chlorpromazine, reserpine and thiopental on mean arterial blood pressure (ABP), mean intracranial pressure (ICP) and cerebral perfusion pressure (CPP) were studied in 43 patients with systemic hypertension and intracranial hypertension due to hemorrhagic cerebrovascular diseases and other causes." | 3.68 | Effects of antihypertensive drugs on intracranial hypertension. ( Handa, Y; Hayashi, M; Hirose, S; Kawano, H; Kobayashi, H; Nozaki, J, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (81.25) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HATTINGER, J | 1 |
| TAKEUCHI, J | 1 |
| TAKEDA, T | 1 |
| UCHIDA, E | 1 |
| OKADA, R | 1 |
| SHINTANI, F | 1 |
| Davis, BR | 2 |
| Vogt, T | 1 |
| Frost, PH | 1 |
| Burlando, A | 1 |
| Cohen, J | 1 |
| Wilson, A | 1 |
| Brass, LM | 1 |
| Frishman, W | 1 |
| Price, T | 1 |
| Stamler, J | 2 |
| Perry, HM | 1 |
| Price, TR | 1 |
| Applegate, WB | 1 |
| Fields, WS | 1 |
| Guralnik, JM | 1 |
| Kuller, L | 1 |
| Pressel, S | 1 |
| Probstfield, JL | 1 |
| Romankiewicz, JA | 1 |
| Hirose, S | 1 |
| Handa, Y | 1 |
| Kobayashi, H | 1 |
| Kawano, H | 1 |
| Nozaki, J | 1 |
| Hayashi, M | 1 |
| Glogner, P | 1 |
| Hariri, NI | 1 |
| Aksu, Y | 1 |
| Falakali, S | 1 |
| Tuncer, OI | 1 |
| Clasen, RA | 1 |
| Pandolfi, S | 1 |
| Casey, D | 1 |
| Freis, ED | 1 |
| Bock, KD | 1 |
| Zervas, NT | 1 |
| Kuwayama, A | 1 |
| Rosoff, C | 1 |
| Salzman, E | 1 |
| Hawkins, WE | 1 |
| Clower, BR | 2 |
| Gottstein, U | 1 |
| McNair, JL | 1 |
| Sanford, RA | 1 |
| Kojimahara, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000514] | Phase 3 | 0 participants | Interventional | 1984-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for reserpine and Cerebral Hemorrhage
| Article | Year |
|---|---|
Pharmacology and clinical use of drugs in hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Aorta; Brain Diseases; Cerebral Hemorrhage; Diazox | 1977 |
2 trials available for reserpine and Cerebral Hemorrhage
| Article | Year |
|---|---|
Risk factors for stroke and type of stroke in persons with isolated systolic hypertension. Systolic Hypertension in the Elderly Program Cooperative Research Group.
Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Brain Ischemia; Cerebral Hemorrhage; Cerebr | 1998 |
Effect of treating isolated systolic hypertension on the risk of developing various types and subtypes of stroke: the Systolic Hypertension in the Elderly Program (SHEP).
Topics: Aged; Antihypertensive Agents; Atenolol; Brain Ischemia; Cerebral Hemorrhage; Chlorthalidone; Double | 2000 |
13 other studies available for reserpine and Cerebral Hemorrhage
| Article | Year |
|---|---|
[A contribution to the therapy of hypertension and postapoplectic sequelae].
Topics: Bendroflumethiazide; Cerebral Hemorrhage; Humans; Hypertension; Potassium; Reserpine | 1962 |
Vascular lesions in experimental renal hypertension, with special reference to effect of hypotensive treatment.
Topics: Arteries; Cerebral Hemorrhage; Coronary Vessels; Guanethidine; Humans; Hydralazine; Hydrochlorothiaz | 1963 |
Effects of antihypertensive drugs on intracranial hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Brain Edema; Cerebral Hemorrhage; Cerebrospina | 1991 |
[Unfavorable and problematic drug combinations. IV].
Topics: Amphetamine; Ataxia; Bone Marrow; Cerebral Hemorrhage; Depression, Chemical; Dicumarol; Dihydroxyphe | 1970 |
Attempt to modify the ionizing radiation induced histopathologic effects on the central nervous system by reserpine administration.
Topics: Animals; Central Nervous System; Cerebral Hemorrhage; Cytoplasm; Hyperemia; Microscopy; Rabbits; Rad | 1972 |
Reserpine in experimental cerebral edema: further observations.
Topics: Animals; Blood Pressure; Body Temperature; Brain Edema; Brain Injuries; Cerebral Cortex; Cerebral He | 1974 |
Hypertension: challenge in preventive medicine.
Topics: Aged; Aneurysm; Cardiovascular Diseases; Cerebral Hemorrhage; Cerebrovascular Disorders; Drug Therap | 1973 |
[What is reliable in the therapy of hypertension?].
Topics: Arteriosclerosis; Cerebral Hemorrhage; Diet, Reducing; Diet, Sodium-Restricted; Guanethidine; Health | 1970 |
Cerebral vascular spasm and reduction of platelet serotonin.
Topics: Animals; Blood Platelets; Cerebral Hemorrhage; Cerebrovascular Disorders; Dogs; Reserpine; Serotonin | 1971 |
Myocardial damage after head trauma and simulated intracranial haemorrhage in mice: the role of the autonomic nervous system.
Topics: Adrenal Glands; Adrenalectomy; Animals; Atropine; Autonomic Nervous System; Cardiomyopathies; Catech | 1971 |
[Therapy of circulatory disorders of the brain and spinal cord].
Topics: Age Factors; Anticoagulants; Brain Edema; Cerebral Hemorrhage; Cerebrovascular Disorders; Coronary D | 1969 |
The effect of reserpine pretreatment on myocardial damage associated with simulated intracranial hemorrhage in mice.
Topics: Animals; Cardiomyopathies; Cerebral Hemorrhage; Female; Mice; Myocardium; Necrosis; Reserpine; Subar | 1970 |
Healing and exacerbation of arterial lesions in rats with experimental hypertension, with special reference to effects of antihypertensive drugs on arterial lesions.
Topics: Animals; Antihypertensive Agents; Arteries; Blood Pressure; Cerebral Arteries; Cerebral Hemorrhage; | 1967 |