reserpine has been researched along with Cardiovascular Diseases in 34 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serum uric acid independently predicts cardiovascular events in older persons with isolated systolic hypertension." | 9.09 | Serum uric acid, diuretic treatment and risk of cardiovascular events in the Systolic Hypertension in the Elderly Program (SHEP). ( Applegate, WB; Di Bari, M; Franse, LV; Pahor, M; Shorr, RI; Somes, GW; Wan, JY, 2000) |
| "The effect of atenolol and reserpine on incidence of strokes, coronary heart disease (CHD), cardiovascular disease (CVD), and mortality was assessed in 4736 persons aged 60 years and older with isolated systolic hypertension." | 9.08 | Effect of atenolol and reserpine on selected events in the systolic hypertension in the elderly program (SHEP). ( Berge, KG; Davis, BR; Hawkins, CM; Kostis, JB; Probstfield, J, 1995) |
| "Although reserpine has an important role in treating patients with hypertension, its appeal was sharply reduced a decade ago when an alleged relationship to breast cancer was reported in case-control studies." | 7.67 | Exclusion bias and the false relationship of reserpine and breast cancer. ( Feinstein, AR; Horwitz, RI, 1985) |
| "Serum uric acid independently predicts cardiovascular events in older persons with isolated systolic hypertension." | 5.09 | Serum uric acid, diuretic treatment and risk of cardiovascular events in the Systolic Hypertension in the Elderly Program (SHEP). ( Applegate, WB; Di Bari, M; Franse, LV; Pahor, M; Shorr, RI; Somes, GW; Wan, JY, 2000) |
| "The effect of atenolol and reserpine on incidence of strokes, coronary heart disease (CHD), cardiovascular disease (CVD), and mortality was assessed in 4736 persons aged 60 years and older with isolated systolic hypertension." | 5.08 | Effect of atenolol and reserpine on selected events in the systolic hypertension in the elderly program (SHEP). ( Berge, KG; Davis, BR; Hawkins, CM; Kostis, JB; Probstfield, J, 1995) |
| "Although reserpine has an important role in treating patients with hypertension, its appeal was sharply reduced a decade ago when an alleged relationship to breast cancer was reported in case-control studies." | 3.67 | Exclusion bias and the false relationship of reserpine and breast cancer. ( Feinstein, AR; Horwitz, RI, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (91.18) | 18.7374 |
| 1990's | 1 (2.94) | 18.2507 |
| 2000's | 1 (2.94) | 29.6817 |
| 2010's | 1 (2.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fajardo, VC | 1 |
| de Oliveira, FLP | 1 |
| Machado-Coelho, GLL | 1 |
| Pimenta, FAP | 1 |
| de Freitas, SN | 1 |
| Ribeiro, ALP | 1 |
| Soares, MMS | 1 |
| Lauria, MW | 1 |
| Farias, RDC | 1 |
| França, IB | 1 |
| do Nascimento Neto, RM | 1 |
| SCHUMANN, H | 1 |
| REHBERG, HG | 1 |
| LASCH, F | 1 |
| THEINL, K | 1 |
| PINES, I | 1 |
| POLAK, F | 1 |
| MENCIK, Z | 1 |
| COFFEE, HL | 1 |
| MASSANO, A | 1 |
| RICHARDSON, JA | 1 |
| BARRERA, F | 1 |
| LAUTSCH, EV | 1 |
| ASCANIO, G | 1 |
| OPPENHEIMER, MJ | 1 |
| SOKOLOV-PONOMAREVA, OD | 1 |
| BEREZHKOV, LF | 1 |
| KUSHELEVSKII, BP | 1 |
| ROZENBLAT, FIa | 1 |
| VALEIKO, NK | 1 |
| KOKOSOV, AN | 1 |
| Risch, SC | 1 |
| Groom, GP | 1 |
| Janowsky, DS | 1 |
| Kostis, JB | 1 |
| Berge, KG | 1 |
| Davis, BR | 1 |
| Hawkins, CM | 1 |
| Probstfield, J | 1 |
| Franse, LV | 1 |
| Pahor, M | 1 |
| Di Bari, M | 1 |
| Shorr, RI | 1 |
| Wan, JY | 1 |
| Somes, GW | 1 |
| Applegate, WB | 1 |
| Guthrie, GP | 1 |
| Genest, J | 1 |
| Kuchel, O | 1 |
| Dowd, JE | 1 |
| Glasunov, IS | 1 |
| Jaksić, Z | 1 |
| Kesić, B | 1 |
| Ray, D | 1 |
| Steinberger, C | 1 |
| Stromberg, J | 1 |
| Vuletić, S | 1 |
| Taguchi, J | 2 |
| Freis, ED | 4 |
| Danilevicius, Z | 1 |
| Horwitz, RI | 1 |
| Feinstein, AR | 1 |
| Sorokina, EI | 1 |
| Bernauer, W | 1 |
| Hahn, F | 1 |
| Alexander, S | 1 |
| Raisfeld, IH | 1 |
| Salomon, MI | 1 |
| Newball, HH | 1 |
| Byar, DP | 1 |
| Britov, AN | 1 |
| Siderskiĭ, AL | 1 |
| Heuillet, G | 1 |
| Saadjian, A | 1 |
| Couve, M | 1 |
| Soulier, R | 1 |
| Murdoch, JL | 1 |
| Walker, BA | 1 |
| Halpern, BL | 1 |
| Kuzma, JW | 1 |
| McKusick, VA | 1 |
| Smith-Vaniz, GT | 1 |
| Clower, BR | 1 |
| Matheny, JL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Thoracic Aortic Dilatation Syndromes - Diagnostic, Incidences, Morbidity, Mortality and Socioeconomical Observations.[NCT02111668] | 120 participants (Actual) | Observational [Patient Registry] | 2013-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for reserpine and Cardiovascular Diseases
| Article | Year |
|---|---|
Interfaces of psychopharmacology and cardiology--Part two.
Topics: Adrenergic alpha-Antagonists; Anti-Anxiety Agents; Antipsychotic Agents; Arrhythmias, Cardiac; Auton | 1981 |
Renin and the therapy of hypertension.
Topics: Animals; Antihypertensive Agents; Cardiovascular Diseases; Clonidine; Diazoxide; Diuretics; Dogs; Fe | 1976 |
Cardiovascular complications of antidepressant therapy. Interactions at the adrenergic neuron.
Topics: Antidepressive Agents; Cardiovascular Diseases; Depression; Drug Interactions; Electrocardiography; | 1972 |
The treatment of hypertension. Why, when and how.
Topics: Arteriosclerosis; Cardiovascular Diseases; Diuretics; Female; Guanethidine; Humans; Hydralazine; Hyd | 1972 |
[Gastro-duodenal disorders in patients with cardiovascular diseases].
Topics: Adrenal Cortex Hormones; Animals; Arteriosclerosis; Cardiovascular Diseases; Cats; Cerebrovascular D | 1971 |
5 trials available for reserpine and Cardiovascular Diseases
| Article | Year |
|---|---|
Effects of vitamin D supplementation on cardiovascular risk factors in shift workers: Study protocol for randomized, double-blind, placebo-controlled clinical trial.
Topics: Adolescent; Adult; Age Factors; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Cholecalcife | 2019 |
Effect of atenolol and reserpine on selected events in the systolic hypertension in the elderly program (SHEP).
Topics: Aged; Antihypertensive Agents; Atenolol; Cardiovascular Diseases; Chlorthalidone; Double-Blind Metho | 1995 |
Serum uric acid, diuretic treatment and risk of cardiovascular events in the Systolic Hypertension in the Elderly Program (SHEP).
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Biomarkers; Cardiovascular Dis | 2000 |
Partial versus complete control of blood pressure in the prevention of hypertensive complications.
Topics: Atrial Fibrillation; Blood Pressure; Cardiovascular Diseases; Clinical Trials as Topic; Follow-Up St | 1975 |
Partial reduction of blood pressure and prevention of complications in hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Clinical Trials as Topic; Follow-U | 1974 |
24 other studies available for reserpine and Cardiovascular Diseases
| Article | Year |
|---|---|
[A new treatment with reserpine for the chronically injured heart].
Topics: Antihypertensive Agents; Cardiovascular Diseases; Heart; Reserpine; Secologanin Tryptamine Alkaloids | 1955 |
[Clinical and experimental studies on the effects of reserpine on the heart & blood circulation and results of this therapy in cardiovascular disorders].
Topics: Cardiovascular Diseases; Coronary Circulation; Humans; Reserpine | 1957 |
[So-called activity of balance of several cardiovascular medicinal agents].
Topics: Cardiovascular Agents; Cardiovascular Diseases; Humans; Prednisone; Reserpine | 1957 |
[Content of isolated & combined short-term reserpine & dihydrazinophthalazine administration in circulatory hypertensive diseases].
Topics: Cardiovascular Diseases; Combined Modality Therapy; Hydralazine; Hypertension; Manipulation, Osteopa | 1958 |
Oral chemotherapy for complicated hypertension.
Topics: Cardiovascular Diseases; Diuretics; Hypertension; Reserpine | 1962 |
[A new preparation in the therapy of female climacteric disorders].
Topics: Cardiovascular Diseases; Female; Flavonoids; Hormones; Humans; Menopause; Mental Disorders; Neurolog | 1962 |
CIRCULATING LEVELS OF CATECHOLAMINES IN ACUTE MYOCARDIAL INFARCTION AND ANGINA PECTORIS.
Topics: Acute Disease; Adrenalectomy; Angina Pectoris; Blood Chemical Analysis; Cardiovascular Diseases; Cat | 1963 |
CARDIOGENIC SHOCK AS INFLUENCED BY RESERPINE.
Topics: Animals; Cardiovascular Diseases; Catecholamines; Dogs; Myocardial Infarction; Research; Reserpine; | 1964 |
[SOME NEW DRUGS IN THE TREATMENT OF RHEUMATIC CHILDREN].
Topics: Adolescent; Alkaloids; Anabolic Agents; Antithyroid Agents; Arrhythmias, Cardiac; Cardiovascular Dis | 1964 |
[Reserpine-anticoagulant therapy of hypertension complicated by stenocardia].
Topics: Angina Pectoris; Anticoagulants; Cardiovascular Diseases; Heart Block; Humans; Hypertension; Reserpi | 1962 |
Design and methodology of the Zagreb preliminary study: response rates at the study stages.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Follow-Up Studies; Humans; Hypercholesterolemia; Hyperte | 1976 |
Editorial: Hypertension is worth treating.
Topics: Blood Pressure; Cardiovascular Diseases; Follow-Up Studies; Humans; Hydralazine; Hydrochlorothiazide | 1975 |
Exclusion bias and the false relationship of reserpine and breast cancer.
Topics: Aged; Breast Neoplasms; Cardiovascular Diseases; Epidemiologic Methods; Female; Humans; Menopause; M | 1985 |
Results of treatment of hypertension.
Topics: Acute Kidney Injury; Antihypertensive Agents; Cardiovascular Diseases; Coronary Disease; Female; Hum | 1971 |
[Treatment with electrosleep and ganglionic blocking preparations of patients with diencephalic syndrome and neurasthenia with autonomic and cardiovascular disorders].
Topics: Adult; Brain Diseases; Cardiovascular Diseases; Diencephalon; Electroencephalography; Electronarcosi | 1966 |
Studies on heart anaphylaxis. II. Effect of histamine and antigen on heart failure in heart-lung-preparation of guinea-pigs.
Topics: Anaphylaxis; Animals; Antigen-Antibody Reactions; Aorta; Blood Pressure; Calcium Chloride; Cardiac O | 1969 |
Effect of cold on the cardiovascular system.
Topics: Angina Pectoris; Blood Pressure; Canada; Cardiac Output; Cardiovascular Diseases; Cardiovascular Phy | 1974 |
Some aspects of chronic renal failure.
Topics: Acidosis; Cardiovascular Diseases; Chronic Kidney Disease-Mineral and Bone Disorder; Diagnosis, Diff | 1973 |
Does reserpine increase prolactin and exacerbate cancer of prostate? Case control study.
Topics: Acid Phosphatase; Aged; Cardiovascular Diseases; Humans; Hypertension; Male; Middle Aged; Prolactin; | 1973 |
Hypertension: challenge in preventive medicine.
Topics: Aged; Aneurysm; Cardiovascular Diseases; Cerebral Hemorrhage; Cerebrovascular Disorders; Drug Therap | 1973 |
[Value of clinico-pharmaco-dynamic tests in phonomechanography].
Topics: Adolescent; Adult; Amyl Nitrite; Angiocardiography; Cardiovascular Diseases; Female; Humans; Kinetoc | 1968 |
Life expectancy and causes of death in the Marfan syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; Aortic Diseases; Cardiovascular Diseases; Child; Female; Human | 1972 |
Report of the panels on cardiovascular drugs from the drug efficacy study.
Topics: Angina Pectoris; Cardiovascular Diseases; Chlorothiazide; Digitalis Glycosides; Drug Industry; Drug | 1970 |
Effects of reserpine on cardiac calcification in DBA mice.
Topics: Animals; Calcinosis; Calcium; Cardiovascular Diseases; Female; Mice; Myocardium; Reserpine | 1969 |