Page last updated: 2024-11-06

reserpine and Cardiac Diseases

reserpine has been researched along with Cardiac Diseases in 45 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	44 (97.78)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (2.22)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
KOHLER, U	1
SZEKELY, A	2
BARCZA, S	1
FOLDES, J	2
MUSA, F	1
MATHELIE-GUINLET, G	1
GARIN, L	1
CASINI, E	1
LEO, F	1
BARCA, S	1
TOSETTI, D	1
ALBANO, T	1
MOTTA, R	1
FESER, A	1
HALPERN, BN	1
MORARD, JC	1
DRUDI-BARACCO, C	1
RIAD, V	1
EL-ZAWAHRY, K	1
MAZZIA, VD	1
PIPITONE, V	3
CARROZZO, M	2
RUSSO, R	2
DEVANNA, F	2
DESTASIO, G	2
RAAB, W	1
DEGROOT, LJ	1
IZAR, G	1
HYMAN, AS	1
WEAVER, KH	1
JASMIN, G	1
BAJUSZ, E	1
LOWN, B	1
EHRLICH, L	1
LIPSCHULTZ, B	1
BLAKE, J	1
Margolis, KL	1
Piller, LB	1
Ford, CE	1
Henriquez, MA	1
Cushman, WC	1
Einhorn, PT	1
Colon, PJ	1
Vidt, DG	1
Christian, R	1
Wong, ND	1
Wright, JT	1
Goff, DC	1
Gál, G	2
Leszkovszky, G	1
Lendvai, J	1
Melli, A	1
Golinelli, G	1
Takata, C	1
Enenkel, W	1
Levey, GS	1
Becker, CE	1
Benowitz, NL	1
Graham, TC	1
Hackel, DB	1
Wechsler, A	1
Hardaker, W	1
Carlier, J	1
Hamburger, JI	1
Paul, S	1
Numo, R	1
Leszkovszky, GP	1
Zbinden, G	1
Moe, RA	1
Raisfeld, IH	1
Teoh, PC	1
Cheah, JS	1
Vander Ark, GD	1
Norton, LW	1
Pomerantz, M	1
Adamska-Dyniewska, H	1
Mason, DT	1
Spann, JF	2
Zelis, R	1
Finnerty, FA	1
Braunwald, E	1
Sonnenblick, EH	1
Buccino, RA	1
Tanabe, T	1
Clower, BR	2
Carrier, O	1
Ball, CR	1
Kawabata, S	1
Douglas, BH	1

Clinical Trials (1)

Trial Overview

Trial			Phase	Enrollment	Study Type	Start Date	Status
[NCT00000542]			Phase 3	0 participants	Interventional	1993-08-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for reserpine and Cardiac Diseases

Article	Year
NEUROGENIC MULTIFOCAL DESTRUCTION OF MYOCARDIAL TISSUE (PATHOGENIC MECHANISM AND ITS PREVENTION). Revue canadienne de biologie, 1963, Volume: 22 Topics: Adrenal Cortex Hormones; Catecholamines; Epinephrine; Heart Diseases; Hypoxia; Myocardial Infarction	1963
[Cardiac therapy in the old patient]. Wiener medizinische Wochenschrift (1946), 1979, Oct-10, Volume: 129, Issue:18 Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Body Water; Calcium; Clonidine; Digitalis Glycos	1979
The heart and hyperthyroidism. Use of beta-adrenergic blocking drugs. The Medical clinics of North America, 1975, Volume: 59, Issue:5 Topics: Adrenergic beta-Antagonists; Guanethidine; Heart; Heart Diseases; Humans; Hyperthyroidism; Propranol	1975
Cardiovascular complications of antidepressant therapy. Interactions at the adrenergic neuron. American heart journal, 1972, Volume: 83, Issue:1 Topics: Antidepressive Agents; Cardiovascular Diseases; Depression; Drug Interactions; Electrocardiography;	1972
[Effect of drugs on the cell potentials of the myocardium]. Polskie Archiwum Medycyny Wewnetrznej, 1969, Volume: 42, Issue:5 Topics: Cardiac Glycosides; Catecholamines; Heart; Heart Diseases; Humans; Membrane Potentials; Quinidine; R	1969
New developments in the understanding of the actions of the digitalis glycosides. Progress in cardiovascular diseases, 1969, Volume: 11, Issue:6 Topics: Animals; Blood Circulation; Calcium; Digitalis Glycosides; Drug Synergism; Heart; Heart Diseases; He	1969

Trials

1 trial available for reserpine and Cardiac Diseases

Article	Year
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:5 Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Canada; Chlorthal	2007

Other Studies

38 other studies available for reserpine and Cardiac Diseases

Article	Year
[Cardiac effect of reserpine in the clinic and in experiments]. Arztliche Forschung, 1957, Mar-10, Volume: 11, Issue:3 Topics: Anti-Arrhythmia Agents; Cardiotonic Agents; Heart; Heart Diseases; Reserpine	1957
[ECG examinations with reserpine in differential diagnosis of organic and functional cardiac disorders]. Orvosi hetilap, 1957, Jun-23, Volume: 98, Issue:25 Topics: Diagnosis, Differential; Electrocardiography; Heart Diseases; Humans; Physical Examination; Reserpin	1957
[Indications and contraindications for reserpine in heart diseases]. Giornale di clinica medica, 1957, Volume: 38, Issue:5 Topics: Anti-Arrhythmia Agents; Cardiotonic Agents; Diuretics; Heart Diseases; Reserpine	1957
The place of reserpine in the treatment of mitral heart disease. Semaine medicale professionelle et medico-sociale, 1957, Dec-30, Volume: 33, Issue:46 Topics: Chronic Disease; Disease; Heart Diseases; Heart Valve Diseases; Humans; Mitral Valve; Reserpine; Rhe	1957
[Further experimental studies to determine the mechanism of action of reserpine on pulmonary circulation in pathological conditions]. Rivista critica di clinica medica, 1957, Oct-31, Volume: 57, Issue:3-4 Topics: Blood Circulation; Cardanolides; Diuretics; Heart Diseases; Humans; Pulmonary Circulation; Reserpine	1957
[Electrocardiographic investigation with reserpine (serpasil) of the separation of structural & functional heart disorders]. Zeitschrift fur arztliche Fortbildung, 1958, Apr-01, Volume: 52, Issue:7 Topics: Diagnosis, Differential; Diagnostic Techniques, Cardiovascular; Electrocardiography; Heart; Heart Di	1958
[Clinical experience with reserpine therapy of heart disease]. Gazzetta medica italiana, 1958, Volume: 117, Issue:8 Topics: Cardanolides; Cardiotonic Agents; Diuretics; Heart Diseases; Humans; Reserpine	1958
[Bradycardic action of reserpine]. Minerva medica, 1958, Oct-17, Volume: 49, Issue:83 Topics: Anti-Arrhythmia Agents; Bradycardia; Enzyme Inhibitors; Heart Diseases; Humans; Reserpine	1958
[On heart therapy with reserpine and Crataegus]. Medizinische Klinik, 1960, Jul-22, Volume: 55 Topics: Cardiotonic Agents; Crataegus; Glycosides; Heart Diseases; Plant Extracts; Reserpine	1960
[Protective effect of reserpine on the lesions in acute myocardial degeneration induced by DL-amphetamine and the suppression of this action by monoamine oxidase inhibitors]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1962, Volume: 156 Topics: Amphetamine; Amphetamines; Behavior; Cardiomyopathies; Heart Diseases; Monoamine Oxidase Inhibitors;	1962
Reserpine in cardiopathies in school age. The Journal of the Egyptian Medical Association, 1962, Volume: 45 Topics: Heart Diseases; Humans; Reserpine; Rheumatic Heart Disease; Schools	1962
EVALUATION OF PREANESTHETIC MEDICATION IN CARDIAC PATIENTS. American heart journal, 1963, Volume: 66 Topics: Antiemetics; Atropine; Barbiturates; Digitalis Glycosides; Heart Diseases; Humans; Narcotics; Preane	1963
[METABOLISM OF SEROTONIN. USE OF THE RESERPINE TOLERANCE CURVE]. Bollettino della Societa italiana di biologia sperimentale, 1963, Nov-30, Volume: 39 Topics: Biliary Dyskinesia; Bronchitis; Heart Diseases; Humans; Liver Diseases; Lung Diseases; Metabolism; N	1963
[METABOLISM OF SEROTONIN. II. DEPLETING EFFECT OF RESERPINE AND CARBETHOXYSYRINGOYL METHYLRESERPATE]. Bollettino della Societa italiana di biologia sperimentale, 1963, Nov-30, Volume: 39 Topics: Biliary Dyskinesia; Drug Hypersensitivity; Heart Diseases; Humans; Liver Diseases; Lung Diseases; Me	1963
THERAPY OF THYROTOXICOSIS. Modern treatment, 1964, Volume: 1 Topics: Adolescent; Antithyroid Agents; Child; Female; Goiter; Graves Disease; Guanethidine; Heart Diseases;	1964
[ON CARDIOTHYREOPATHIES. THEIR TREATMENT]. Minerva medica, 1964, Jun-13, Volume: 55 Topics: Digitalis Glycosides; Diiodotyrosine; Diuretics; Heart Diseases; Humans; Imidazoles; Iodine Isotopes	1964
THE CARDIAC ATHLETE. RECENT STUDIES IN SPORTS MEDICINE. Texas state journal of medicine, 1964, Volume: 60 Topics: Athletes; Atrial Fibrillation; Classification; Exercise Test; Heart; Heart Diseases; Humans; Hydroch	1964
THE HEART AND ACUTE GLOMERULONEPHRITIS. Maryland state medical journal, 1964, Volume: 13 Topics: Child; Diet, Sodium-Restricted; Digitalis Glycosides; Drug Therapy; Glomerulonephritis; Heart Diseas	1964
[Action of serotonin, of 48/80 and of reserpine on the lesions of calcinosis induced by various agents in rats]. Revue canadienne de biologie, 1962, Volume: 21 Topics: Animals; Calcification, Physiologic; Calcinosis; Heart Diseases; Kidney Diseases; Rats; Reserpine; S	1962
Effect of digitalis in patients receiving reserpine. Circulation, 1961, Volume: 24 Topics: Cardiotonic Agents; Digitalis; Diuretics; Enzyme Inhibitors; Heart Diseases; Reserpine; Strophanthin	1961
Quantitative evaluation of morphologic changes in experimentally induced myocardial necrosis. Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1966, Volume: 14, Issue:6 Topics: Animals; Guanethidine; Heart Diseases; Iproniazid; Isoproterenol; Male; Monoamine Oxidase Inhibitors	1966
[Clinical studies of the vasodilating activity of a new drug with adrenosympatholytic action]. Minerva cardioangiologica, 1967, Volume: 15, Issue:6 Topics: Adult; Aged; Arteriosclerosis; Endarteritis; Ergot Alkaloids; Female; Heart Diseases; Humans; Intrac	1967
[Effects of reserpine on pulmonary circulation and respiratory function, especially on pulmonary hypertension]. Japanese circulation journal, 1967, Volume: 31, Issue:4 Topics: Adolescent; Adult; Aged; Blood Gas Analysis; Blood Pressure; Bronchial Diseases; Chronic Disease; Fe	1967
Hypertensive emergencies. The Medical clinics of North America, 1979, Volume: 63, Issue:1 Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Brain Diseases	1979
The effects of reserpine on myocardial lesions in dogs subjected to hemorrhagic shock. Circulatory shock, 1977, Volume: 4, Issue:2 Topics: Animals; Dogs; Female; Heart Diseases; Hemorrhage; Male; Myocardium; Norepinephrine; Reserpine; Shoc	1977
[Treatment of cardiac complications in hyperthyroidism]. Revue medicale de Liege, 1973, Sep-01, Volume: 28, Issue:17 Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Digitalis Glycosides; Guanethidine; Heart Disease	1973
When and how to use higher 131-I doses for hyperthyroidism. The New England journal of medicine, 1968, Dec-19, Volume: 279, Issue:25 Topics: Adult; Age Factors; Aged; Antithyroid Agents; Female; Follow-Up Studies; Graves Disease; Heart Disea	1968
[Metabolism of serotonin. IX. Value of the L-tryptophan tolerance test and the carbethoxysyringoyl methylreserpate tolerance test]. Bollettino della Societa italiana di biologia sperimentale, 1964, Nov-15, Volume: 40, Issue:21 Topics: Female; Heart Diseases; Humans; Infections; Liver Diseases; Male; Mesenteric Lymphadenitis; Reserpin	1964
Observations on isoprenaline-induced myocardial necroses. The Journal of pharmacy and pharmacology, 1967, Volume: 19, Issue:4 Topics: Animals; Guanethidine; Heart Diseases; Iproniazid; Isoproterenol; Male; Monoamine Oxidase Inhibitors	1967
Pharmacological studies on heart muscle lesions induced by isoproterenol. Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amides; Animals; Antihypertensive Agents;	1969
Electrocardiographic changes in hyperthyroidism after adrenergic blockade with reserpine and propranolol. The Medical journal of Australia, 1973, Jul-21, Volume: 2, Issue:3 Topics: Adolescent; Adult; Catecholamines; Electrocardiography; Female; Heart Diseases; Humans; Hyperthyroid	1973
The effects of brain stem compression on the heart. Surgical neurology, 1974, Volume: 2, Issue:4 Topics: Animals; Arrhythmias, Cardiac; Atropine; Blood Pressure; Bradycardia; Brain Injuries; Brain Stem; Ca	1974
Hypertensive encephalopathy. The American journal of medicine, 1972, Volume: 52, Issue:5 Topics: Anxiety; Brain Diseases; Brain Edema; Coma; Diazoxide; Female; Furosemide; Glomerulonephritis; Heada	1972
Effects of heart failure, ventricular hypertrophy, and alterations in the thyroid state on the contractility of isolated cardiac muscle. Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1 Topics: Animals; Cardiomyopathies; Cats; Heart; Heart Diseases; Hyperthyroidism; Hypertrophy; Hypothyroidism	1969
A comment on the interaction between digitalis and other drugs. Japanese heart journal, 1968, Volume: 9, Issue:3 Topics: Animals; Arrhythmias, Cardiac; Cardiac Glycosides; Catecholamines; Heart Diseases; Humans; Reserpine	1968
The protective action of reserpine against diet-induced atrial thrombosis. European journal of pharmacology, 1967, Volume: 2, Issue:2 Topics: Animals; Choline; Coronary Disease; Dietary Fats; Dietary Proteins; Female; Heart Atria; Heart Disea	1967
[Effects of reserpine on respiratory functions, with special reference to the increase of anoxemia in cardiac and pulmonary diseases]. Japanese circulation journal, 1968, Volume: 32, Issue:2 Topics: Aortic Valve Stenosis; Asthma; Blood Gas Analysis; Bronchiectasis; Bronchitis; Carbon Dioxide; Cardi	1968
The effect of estrogen, reserpine, and pregnancy on development of diet-induced atrial thrombosis in mice. American journal of obstetrics and gynecology, 1968, Dec-01, Volume: 102, Issue:7 Topics: Animals; Diet, Atherogenic; Estrogens; Female; Heart Atria; Heart Diseases; Mice; Pregnancy; Pregnan	1968