reserpine has been researched along with Carcinoma, Renal Cell in 2 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Carcinoma, Renal Cell: A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Early retrospective studies implicated reserpine in breast cancer, but the drug was later absolved by prospective analyses." | 4.80 | Carcinogenicity of cardiovascular drugs. ( Goldbourt, U; Grossman, E; Messerli, FH, 1999) |
| "The association between diuretics and renal cell carcinoma was analysed in 4389 cases and 6566 controls, yielding a pooled OR of 1." | 2.41 | Antihypertensive therapy and the risk of malignancies. ( Goldbourt, U; Grossman, E; Messerli, FH, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grossman, E | 2 |
| Messerli, FH | 2 |
| Goldbourt, U | 2 |
2 reviews available for reserpine and Carcinoma, Renal Cell
| Article | Year |
|---|---|
Carcinogenicity of cardiovascular drugs.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Brea | 1999 |
Antihypertensive therapy and the risk of malignancies.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aten | 2001 |