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reserpine and Carcinogenesis

reserpine has been researched along with Carcinogenesis in 3 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.

Research Excerpts

ExcerptRelevanceReference
"Reserpine is a natural indole alkaloid isolated from Rauwolfia serpentina and has potent antioxidant, antimicrobial, and anti-mutagenic properties."5.62Reserpine inhibits DNA repair, cell proliferation, invasion and induces apoptosis in oral carcinogenesis via modulation of TGF-β signaling. ( Ahmed Abdul, BA; Alarifi, S; Ali, D; Ramu, AK; Syed Abuthakir, MH, 2021)
"Reserpine is a natural indole alkaloid isolated from Rauwolfia serpentina and has potent antioxidant, antimicrobial, and anti-mutagenic properties."1.62Reserpine inhibits DNA repair, cell proliferation, invasion and induces apoptosis in oral carcinogenesis via modulation of TGF-β signaling. ( Ahmed Abdul, BA; Alarifi, S; Ali, D; Ramu, AK; Syed Abuthakir, MH, 2021)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Kim, WH1
Jeong, P1
Kim, SW1
Cho, H1
Lee, JM1
Seo, S1
Shen, H1
Ahn, Y1
Jung, DW1
Kim, YC1
Williams, DR1
Ramu, AK1
Ali, D1
Alarifi, S1
Syed Abuthakir, MH1
Ahmed Abdul, BA1
LACASSAGNE, A1
HURST, L1

Other Studies

3 other studies available for reserpine and Carcinogenesis

ArticleYear
A novel indirubin derivative that increases somatic cell plasticity and inhibits tumorigenicity.
    Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13

    Topics: Carcinogenesis; Cell Plasticity; Humans; Indoles; Protein Kinase Inhibitors

2019
Reserpine inhibits DNA repair, cell proliferation, invasion and induces apoptosis in oral carcinogenesis via modulation of TGF-β signaling.
    Life sciences, 2021, Jan-01, Volume: 264

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogenesis; Cell Proliferation; Cricetinae

2021
[INFLUENCE OF SIMULTANEOUS ADMINISTRATION OF RESERPINE AND A CORTICOID ON CARCINOGENESIS OF RAT LIVER BY P-DIMETHYLAMINOAZOBENZENE (DAB)].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1963, Sep-02, Volume: 257

    Topics: Adenoma, Bile Duct; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinogenesis; Chemical and Drug

1963