reserpine has been researched along with Brain Vascular Disorders in 44 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effects of benidipine hydrochloride or triple therapy (hydralazine, reserpine, and hydrochlorothiazide) on renal cortical and medullary intrinsic antioxidant enzyme (AOE) activity were evaluated in stroke-prone spontaneously hypertensive rats (SHR-SP) as an animal model for human essential hypertension with cerebral stroke." | 3.69 | Effects of benidipine hydrochloride on antioxidant enzyme activity in stroke-prone spontaneous hypertensive rats (SHR-SP). ( Fukui, M; Shou, I; Takahashi, Y; Tomino, Y; Wang, LN, 1997) |
| "If atenolol was contraindicated, 0." | 2.67 | Impact of the treatment of isolated systolic hypertension on behavioral variables. Results from the systolic hypertension in the elderly program. ( Applegate, WB; Camel, GH; Greenlick, MR; Hadley, E; Luhr, J; Moye, L; Perry, HM; Pressel, S; Shekelle, RB; Wittes, J, 1994) |
| "The reduction in coronary disease is consistent with predictions based on prospective epidemiological studies and is concordant with other recent intervention trials." | 2.67 | Implications of the systolic hypertension in the elderly program. The Systolic Hypertension in the Elderly Program Cooperative Research Group. ( , 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (86.36) | 18.7374 |
| 1990's | 6 (13.64) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| LWIN, R | 1 |
| ATARASHI, J | 1 |
| YOSHIMURA, M | 1 |
| TOGNELLA, S | 1 |
| BIGNOTTI, G | 1 |
| NOZAWA, G | 1 |
| HOSHINO, T | 1 |
| LEONBERG, SC | 1 |
| GREEN, JB | 1 |
| ELLIOTT, FA | 1 |
| RAYNOR, RB | 1 |
| MCMURTRY, JG | 1 |
| DRACHEVA, ZN | 2 |
| TIAZHKOROB, AM | 1 |
| KUCHEROVA, LL | 1 |
| KANDRUSINA, GA | 1 |
| MANKOVSKII, NB | 1 |
| VAINSHTOK, IB | 1 |
| Eninia, GI | 1 |
| Smeltere, ES | 1 |
| Godlevska, MA | 1 |
| Uzulinia, IP | 1 |
| Freis, E | 1 |
| Vakaliuk, PM | 1 |
| Shvedenko, LA | 1 |
| Iurkevich, ST | 1 |
| Nikulin, KE | 1 |
| Ilika, VG | 1 |
| Applegate, WB | 1 |
| Pressel, S | 1 |
| Wittes, J | 1 |
| Luhr, J | 1 |
| Shekelle, RB | 1 |
| Camel, GH | 1 |
| Greenlick, MR | 1 |
| Hadley, E | 1 |
| Moye, L | 1 |
| Perry, HM | 1 |
| Shou, I | 1 |
| Wang, LN | 1 |
| Takahashi, Y | 1 |
| Fukui, M | 1 |
| Tomino, Y | 1 |
| Davis, BR | 1 |
| Vogt, T | 1 |
| Frost, PH | 1 |
| Burlando, A | 1 |
| Cohen, J | 1 |
| Wilson, A | 1 |
| Brass, LM | 1 |
| Frishman, W | 1 |
| Price, T | 1 |
| Stamler, J | 1 |
| Singer, RB | 1 |
| Spotnitz, HM | 1 |
| Becker, CE | 1 |
| Benowitz, NL | 1 |
| Fleischmann, LE | 1 |
| Kogure, K | 1 |
| Scheinberg, P | 1 |
| Kishikawa, H | 1 |
| Busto, R | 1 |
| Reinmuth, OM | 1 |
| Moskowitz, MA | 1 |
| Meyer, E | 1 |
| Wurtman, RJ | 1 |
| Lavyne, MH | 1 |
| Zervas, T | 1 |
| Petrovitch, H | 1 |
| Vogt, TM | 1 |
| Berge, KG | 1 |
| Harper, SL | 1 |
| Eichbaum, FW | 1 |
| Spanoudis, S | 1 |
| Aguiar, A | 1 |
| Ramos, AO | 1 |
| Douglas, AS | 1 |
| Freis, ED | 2 |
| Amery, A | 1 |
| Fagard, R | 1 |
| Misotten, A | 1 |
| Koch-Weser, J | 1 |
| Laidlaw, JC | 1 |
| Berzewski, H | 1 |
| Spach, MO | 1 |
| Imbs, JL | 1 |
| Schwartz, J | 1 |
| Breslin, DJ | 1 |
| Britov, AN | 1 |
| Siderskiĭ, AL | 1 |
| Hidaka, T | 1 |
| Finnerty, FA | 2 |
| Zervas, NT | 1 |
| Kuwayama, A | 1 |
| Rosoff, C | 1 |
| Salzman, E | 1 |
| Meyer, JS | 1 |
| Eadie, GA | 1 |
| Ericsson, AD | 1 |
| Hoobler, SW | 1 |
| MacMahon, HR | 1 |
| Gottstein, U | 1 |
| Kiesewetter, E | 1 |
| Kahn, AM | 1 |
| Davis, S | 1 |
| Carey, JS | 1 |
| Cioffi, F | 1 |
| Bisiani, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000514] | Phase 3 | 0 participants | Interventional | 1984-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for reserpine and Brain Vascular Disorders
| Article | Year |
|---|---|
[GENERAL PRINCIPLES IN THE DRUG THERAPY OF CEREBROVASCULAR DISORDERS].
Topics: Adenosine Triphosphate; Adrenal Cortex Hormones; Antihypertensive Agents; Blood Circulation; Cerebro | 1964 |
[CARDIOVASCULAR SYNDROMES IN POLYCYTHEMIA VERA].
Topics: Anti-Bacterial Agents; Anticoagulants; Bloodletting; Cerebrovascular Disorders; Electrocardiography; | 1964 |
Elderly hypertensive patient. Epidemiologic review.
Topics: Adult; Age Factors; Aged; Cerebrovascular Disorders; Female; Humans; Hydrochlorothiazide; Hypertensi | 1978 |
Isolated systolic hypertension: lowering the risk of stroke in older patients. SHEP Cooperative Research Group.
Topics: Aged; Atenolol; Cerebrovascular Disorders; Chlorthalidone; Coronary Disease; Double-Blind Method; Hu | 1992 |
Management of thrombotic diseases.
Topics: Anticoagulants; Aspirin; Blood Coagulation; Blood Platelets; Cerebrovascular Disorders; Coronary Dis | 1971 |
Effectiveness of drug therapy in hypertension: present status. A review.
Topics: Antihypertensive Agents; Cerebrovascular Disorders; Coronary Disease; Eye Diseases; Ganglionic Block | 1971 |
Hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Coronary D | 1974 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Diazoxide; Emergencies; Humans; Hyd | 1969 |
[Gastro-duodenal disorders in patients with cardiovascular diseases].
Topics: Adrenal Cortex Hormones; Animals; Arteriosclerosis; Cardiovascular Diseases; Cats; Cerebrovascular D | 1971 |
8 trials available for reserpine and Brain Vascular Disorders
| Article | Year |
|---|---|
[Current state of the treatment of arterial hypertension].
Topics: Adult; Aged; Cerebrovascular Disorders; Clinical Trials as Topic; Heart Failure; Humans; Hydralazine | 1980 |
Impact of the treatment of isolated systolic hypertension on behavioral variables. Results from the systolic hypertension in the elderly program.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Atenolol; Cerebrovascular Disorders; Chlorthali | 1994 |
Implications of the systolic hypertension in the elderly program. The Systolic Hypertension in the Elderly Program Cooperative Research Group.
Topics: Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Atenolol; Blood Pressure; Cerebrovasc | 1993 |
Risk factors for stroke and type of stroke in persons with isolated systolic hypertension. Systolic Hypertension in the Elderly Program Cooperative Research Group.
Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Brain Ischemia; Cerebral Hemorrhage; Cerebr | 1998 |
Isolated systolic hypertension: lowering the risk of stroke in older patients. SHEP Cooperative Research Group.
Topics: Aged; Atenolol; Cerebrovascular Disorders; Chlorthalidone; Coronary Disease; Double-Blind Method; Hu | 1992 |
Effects of treatment on morbidity in hypertension. 3. Influence of age, diastolic pressure, and prior cardiovascular disease; further analysis of side effects.
Topics: Adult; Age Factors; Aged; Aneurysm; Atrial Fibrillation; Blood Glucose; Blood Pressure; Cerebrovascu | 1972 |
Hypertension: a challenge in preventive medicine.
Topics: Age Factors; Attitude to Health; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disea | 1974 |
A pilot study of antihypertensive therapy in cerebrovascular disease.
Topics: Adult; Cerebrovascular Disorders; Clinical Trials as Topic; Depression; Female; Humans; Hypertension | 1967 |
28 other studies available for reserpine and Brain Vascular Disorders
| Article | Year |
|---|---|
Medical management of cerebrovascular accidents.
Topics: Anticoagulants; Antihypertensive Agents; Cerebrovascular Disorders; Chymotrypsin; Disease Management | 1963 |
[ON APOPLEXY IN A CERTAIN REGION AND THE PROPHYLACTIC USE OF ANTIHYPERTENSIVE AGENTS].
Topics: Adolescent; Antihypertensive Agents; Benzothiadiazines; Cerebrovascular Disorders; Child; Epidemiolo | 1964 |
THE RESPONSE OF STROKE PATIENTS TO VERY SMALL DOSES OF PARENTERAL RESERPINE.
Topics: Aged; Blood Pressure Determination; Cerebrovascular Disorders; Drug Therapy; Epilepsy; Geriatrics; H | 1964 |
PREVENTION OF SEROTONIN-PRODUCED CEREBRAL VASOSPASM: AN EVALUATION OF BLOCKING AGENTS.
Topics: Blood Platelets; Cats; Cerebral Arteries; Cerebrovascular Disorders; Chlorpromazine; Pharmacology; P | 1963 |
[USE OF RESERPINE ASSCIATED WITH HYPOTHIAZIDE IN THE TREATMENT OF CEREBRAL FORMS OF HYPERTENSION].
Topics: Cerebrovascular Disorders; Drug Therapy; Humans; Hydrochlorothiazide; Hypertension; Reserpine | 1964 |
[TREATMENT OF AGED PATIENTS WITH CEREBRAL FORMS OF HYPERTENSION WITH HYPOTHIAZIDE AND RESERPINE].
Topics: Cerebrovascular Disorders; Humans; Hydrochlorothiazide; Hypertension; Reserpine | 1965 |
[Characteristics of the action of gemiton, adelfan and dopegit on cerebral circulation in arterial hypertension].
Topics: Aged; Antihypertensive Agents; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disea | 1984 |
[Changes In myocardial contractile function and microcirculation in hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Cerebrovascular Disorders; Conjunctiva; Drug Combinations; Dru | 1982 |
Effects of benidipine hydrochloride on antioxidant enzyme activity in stroke-prone spontaneous hypertensive rats (SHR-SP).
Topics: Animals; Antioxidants; Blood Pressure; Calcium Channel Blockers; Catalase; Cerebrovascular Disorders | 1997 |
Stroke in the elderly treated for systolic hypertension (SHEP).
Topics: Actuarial Analysis; Age Factors; Aged; Aged, 80 and over; Atenolol; Cerebrovascular Disorders; Chlor | 1991 |
Hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Brain Diseases | 1979 |
Management of hypertensive crisis in children.
Topics: Acute Disease; Adolescent; Cerebrovascular Disorders; Child; Child, Preschool; Diazoxide; Humans; Hy | 1977 |
Hypothesis for rational therapy in acute stroke.
Topics: Acute Disease; Aminophylline; Animals; Cerebrovascular Disorders; Disease Models, Animal; Drug Evalu | 1976 |
Attenuation by catecholamine antagonists of the hypothermia that follows cerebral infarction in gerbils.
Topics: Animals; Catecholamines; Cerebrovascular Disorders; Dopamine; Gerbillinae; Hydroxydopamines; Hypothe | 1975 |
Antihypertensive drug therapy prevents cerebral microvascular abnormalities in hypertensive rats.
Topics: Adaptation, Physiological; Animals; Antihypertensive Agents; Blood Flow Velocity; Cerebrovascular Ci | 1987 |
Influence of antiadrenergic measures on the blood catecholamine level in protracted intracranial hypertension.
Topics: Adrenalectomy; Analysis of Variance; Animals; Blood Pressure; Cerebrovascular Disorders; Dogs; Elect | 1969 |
[Indications of antihypertensive treatment in non-malignant hypertension].
Topics: Antihypertensive Agents; Aortic Aneurysm; Benzothiadiazines; Cerebrovascular Disorders; Coronary Dis | 1974 |
[Therapy of acute cerebrovascular insufficiency].
Topics: Anticoagulants; Brain Edema; Cardiac Glycosides; Cerebrovascular Disorders; Dextrans; Humans; Inject | 1972 |
[Malignant nephroangiosclerosis. Development and treatment].
Topics: Adult; Aniline Compounds; Antihypertensive Agents; Cerebrovascular Disorders; Diagnosis, Differentia | 1972 |
Hypertension: challenge in preventive medicine.
Topics: Aged; Aneurysm; Cardiovascular Diseases; Cerebral Hemorrhage; Cerebrovascular Disorders; Drug Therap | 1973 |
[Effects of various therapeutic agents on hemorrhagic diathesis and blood clotting factors in aged patients with cerebrovascular disorders].
Topics: Adrenochrome; Aged; Blood Coagulation; Blood Coagulation Tests; Cerebrovascular Disorders; Female; H | 1972 |
Hypertension is different in blacks.
Topics: Adult; Age Factors; Black People; Blood Pressure; Cerebrovascular Disorders; Female; Humans; Hyperte | 1971 |
Cerebral vascular spasm and reduction of platelet serotonin.
Topics: Animals; Blood Platelets; Cerebral Hemorrhage; Cerebrovascular Disorders; Dogs; Reserpine; Serotonin | 1971 |
[Therapy of circulatory disorders of the brain and spinal cord].
Topics: Age Factors; Anticoagulants; Brain Edema; Cerebral Hemorrhage; Cerebrovascular Disorders; Coronary D | 1969 |
[Physiopathological deliberations on the significance of long-term therapy for hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Chlorothiazide; Fem | 1967 |
Hypertensive encephalopathy.
Topics: Brain Diseases; Cerebrovascular Circulation; Cerebrovascular Disorders; Coma; Diagnosis, Differentia | 1968 |
Complications of antihypertensive therapy for dissecting thoracic aortic aneurysms.
Topics: Acute Kidney Injury; Adult; Aged; Aorta, Thoracic; Aortic Aneurysm; Aortic Rupture; Aortography; Arr | 1969 |
[Triamteril-chlorothiazide-reserpine combination in prophylaxis of cerebrovascular accidents in patients with cerebral vascular lesions with elevated arterial hypertension].
Topics: Cerebrovascular Disorders; Chlorothiazide; Humans; Hypertension; Reserpine; Triamterene | 1965 |