reserpine has been researched along with Brain Neoplasms in 10 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " 5-aminolevulinic acid (ALA) is metabolized to fluorescent protoporphyrin IX (PpIX) specifically in tumor cells, and therefore clinically used as a reagent for photodynamic diagnosis (PDD) and therapy (PDT) of cancers including gliomas." | 7.85 | Enhancement of 5-aminolevulinic acid-based fluorescence detection of side population-defined glioma stem cells by iron chelation. ( Hagiya, Y; Kokubu, Y; Murota, Y; Ogura, SI; Sugiyama, Y; Tabu, K; Taga, T; Wang, W, 2017) |
| "Reserpine was found to enhance the effect of ACNU on ACNU-resistant C6 glioma (C6/ACNU)." | 7.67 | [Enhanced effect of reserpine on growth-inhibitory action of ACNU on ACNU resistance C6 glioma]. ( Hayakawa, T; Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T, 1984) |
| "Reserpine enhanced in vitro the cytotoxicity of 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride (ACNU) in both the C6 glioma and its ACNU-resistant subline, C6/ACNU." | 7.67 | Modulation in vitro and in vivo of ACNU resistance in a subline of C6 glioma with reserpine. ( Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T, 1987) |
| " 5-aminolevulinic acid (ALA) is metabolized to fluorescent protoporphyrin IX (PpIX) specifically in tumor cells, and therefore clinically used as a reagent for photodynamic diagnosis (PDD) and therapy (PDT) of cancers including gliomas." | 3.85 | Enhancement of 5-aminolevulinic acid-based fluorescence detection of side population-defined glioma stem cells by iron chelation. ( Hagiya, Y; Kokubu, Y; Murota, Y; Ogura, SI; Sugiyama, Y; Tabu, K; Taga, T; Wang, W, 2017) |
| "Reserpine was found to enhance the effect of ACNU on ACNU-resistant C6 glioma (C6/ACNU)." | 3.67 | [Enhanced effect of reserpine on growth-inhibitory action of ACNU on ACNU resistance C6 glioma]. ( Hayakawa, T; Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T, 1984) |
| "Reserpine enhanced in vitro the cytotoxicity of 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride (ACNU) in both the C6 glioma and its ACNU-resistant subline, C6/ACNU." | 3.67 | Modulation in vitro and in vivo of ACNU resistance in a subline of C6 glioma with reserpine. ( Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T, 1987) |
| "Membrane-modifying agents such as reserpine, calcium antagonists (nicardipine, verapamil) and calmodulin inhibitor (trifluoperazine) were found to enhance the cytotoxicity of ACNU in vitro and in vivo in ACNU-resistant C 6 (C 6/ACNU) glioma." | 3.67 | [Possibility of overcoming of ACNU resistance in an ACNU-resistant subline of C6 rat glioma]. ( Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, W | 1 |
| Tabu, K | 1 |
| Hagiya, Y | 1 |
| Sugiyama, Y | 1 |
| Kokubu, Y | 1 |
| Murota, Y | 1 |
| Ogura, SI | 1 |
| Taga, T | 1 |
| NISHIKAWA, M | 1 |
| PEARCE, A | 1 |
| Briggs, RC | 1 |
| Steffen, DH | 1 |
| Yoshida, T | 4 |
| Shimizu, K | 4 |
| Ushio, Y | 4 |
| Hayakawa, T | 2 |
| Mogami, H | 4 |
| Sakamoto, Y | 4 |
| Fink, M | 1 |
| Abrams, R | 1 |
10 other studies available for reserpine and Brain Neoplasms
| Article | Year |
|---|---|
Enhancement of 5-aminolevulinic acid-based fluorescence detection of side population-defined glioma stem cells by iron chelation.
Topics: Aminolevulinic Acid; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Biotransforma | 2017 |
[THE CENTRAL NERVOUS SYSTEM AND THE PITUITARY-ADRENAL SYSTEM].
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Benzothiadiazines; | 1964 |
PITFALLS IN THE DIAGNOSIS OF PSYCHIATRIC DISEASE.
Topics: Anxiety; Anxiety Disorders; Brain Neoplasms; Carcinoid Tumor; Depression; Diagnosis; Drug Therapy; G | 1965 |
Use of brain scanning for evaluation of the mentally disturbed patient.
Topics: Adult; Aged; Brain Neoplasms; Female; Humans; Male; Radiography; Radionuclide Imaging; Reserpine; Te | 1967 |
[Enhanced effect of reserpine on growth-inhibitory action of ACNU on ACNU resistance C6 glioma].
Topics: Animals; Brain Neoplasms; DNA Repair; Drug Resistance; Drug Synergism; Glioma; Growth Inhibitors; Ni | 1984 |
Editorial: Reserpine and breast cancer.
Topics: Age Factors; Aged; Brain Neoplasms; Breast Neoplasms; Female; Humans; Kidney Neoplasms; Middle Aged; | 1975 |
[Enhancing effect of reserpine upon the cytotoxicity of ACNU on ACNU-resistant glioma cells].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Membrane Permeability; Cells, C | 1986 |
Modulation in vitro and in vivo of ACNU resistance in a subline of C6 glioma with reserpine.
Topics: Animals; Brain Neoplasms; Cell Line; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Gli | 1987 |
[Possibility of overcoming of ACNU resistance in an ACNU-resistant subline of C6 rat glioma].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Cells, Cultured; Drug Resistance; Drug T | 1986 |
Answers to questions frequently asked about ECT.
Topics: Age Factors; Anesthesia, Intravenous; Brain Damage, Chronic; Brain Neoplasms; Depression; Electrocon | 1972 |