reserpine has been researched along with Brain Ischemia in 7 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shah, A | 1 |
| Garzon-Muvdi, T | 1 |
| Mahajan, R | 1 |
| Duenas, VJ | 1 |
| Quiñones-Hinojosa, A | 1 |
| Locatelli, C | 1 |
| Conte, G | 1 |
| Palatini, P | 1 |
| Stritoni, P | 1 |
| Spandri, P | 1 |
| Braggion, M | 1 |
| Okajima, Y | 1 |
| Nishi, K | 1 |
| Davis, BR | 2 |
| Vogt, T | 1 |
| Frost, PH | 1 |
| Burlando, A | 1 |
| Cohen, J | 1 |
| Wilson, A | 1 |
| Brass, LM | 1 |
| Frishman, W | 1 |
| Price, T | 1 |
| Stamler, J | 2 |
| Perry, HM | 1 |
| Price, TR | 1 |
| Applegate, WB | 1 |
| Fields, WS | 1 |
| Guralnik, JM | 1 |
| Kuller, L | 1 |
| Pressel, S | 1 |
| Probstfield, JL | 1 |
| Yamamoto, M | 1 |
| Kawabata, S | 1 |
| Shimizu, M | 1 |
| Thureson-Klein, A | 1 |
| Kong, JY | 1 |
| Klein, RL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000514] | Phase 3 | 0 participants | Interventional | 1984-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for reserpine and Brain Ischemia
| Article | Year |
|---|---|
Animal models of neurological disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic Agents; Amyloid beta-Protein Precursor; Ani | 2010 |
2 trials available for reserpine and Brain Ischemia
| Article | Year |
|---|---|
Risk factors for stroke and type of stroke in persons with isolated systolic hypertension. Systolic Hypertension in the Elderly Program Cooperative Research Group.
Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Brain Ischemia; Cerebral Hemorrhage; Cerebr | 1998 |
Effect of treating isolated systolic hypertension on the risk of developing various types and subtypes of stroke: the Systolic Hypertension in the Elderly Program (SHEP).
Topics: Aged; Antihypertensive Agents; Atenolol; Brain Ischemia; Cerebral Hemorrhage; Chlorthalidone; Double | 2000 |
4 other studies available for reserpine and Brain Ischemia
| Article | Year |
|---|---|
[A case of severe transitory postural hypotension].
Topics: Aged; Antihypertensive Agents; Brain Ischemia; Chlorthalidone; Female; Humans; Hypotension, Orthosta | 1980 |
Analysis of inhibitory and excitatory actions of dopamine on chemoreceptor discharges of carotid body of cat in vivo.
Topics: Animals; Brain Ischemia; Carotid Body; Cats; Chemoreceptor Cells; Dopamine; Electrophysiology; Halop | 1981 |
Pharmacological effects of indeloxazine, a new cerebral activator, on brain functions distinct from other cerebral metabolic enhancers.
Topics: Animals; Avoidance Learning; Biotransformation; Body Temperature; Brain; Brain Ischemia; Cats; Cauda | 1989 |
Enkephalin and neuropeptide Y in large cerebral arteries of the pig after ischemia and reserpine.
Topics: Animals; Brain Ischemia; Cerebral Arteries; Enkephalins; Neuropeptide Y; Reserpine; Swine | 1989 |