reserpine has been researched along with Brain Edema in 10 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
Excerpt | Relevance | Reference |
---|---|---|
"The effects of antihypertensive drugs, such as nifedipine, chlorpromazine, reserpine and thiopental on mean arterial blood pressure (ABP), mean intracranial pressure (ICP) and cerebral perfusion pressure (CPP) were studied in 43 patients with systemic hypertension and intracranial hypertension due to hemorrhagic cerebrovascular diseases and other causes." | 3.68 | Effects of antihypertensive drugs on intracranial hypertension. ( Handa, Y; Hayashi, M; Hirose, S; Kawano, H; Kobayashi, H; Nozaki, J, 1991) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (90.00) | 18.7374 |
1990's | 1 (10.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
BULLE, PH | 1 |
Hirose, S | 1 |
Handa, Y | 1 |
Kobayashi, H | 1 |
Kawano, H | 1 |
Nozaki, J | 1 |
Hayashi, M | 1 |
Philipp, T | 1 |
Nast, HP | 1 |
Clasen, RA | 2 |
Pandolfi, S | 2 |
Casey, D | 1 |
Laing, I | 1 |
Oelke, D | 1 |
Hass, GM | 1 |
Koch-Weser, J | 1 |
Berzewski, H | 1 |
Breslin, DJ | 1 |
Finnerty, FA | 1 |
Gottstein, U | 1 |
2 reviews available for reserpine and Brain Edema
Article | Year |
---|---|
Hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Coronary D | 1974 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Diazoxide; Emergencies; Humans; Hyd | 1969 |
8 other studies available for reserpine and Brain Edema
Article | Year |
---|---|
Effects of reserpine and chlorpromazine in prevention of cerebral edema and reversible cell damage.
Topics: Biomedical Research; Brain Edema; Chlorpromazine; Edema; Reserpine | 1957 |
Effects of antihypertensive drugs on intracranial hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Brain Edema; Cerebral Hemorrhage; Cerebrospina | 1991 |
[Hypertensive emergencies].
Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies; | 1974 |
Reserpine in experimental cerebral edema: further observations.
Topics: Animals; Blood Pressure; Body Temperature; Brain Edema; Brain Injuries; Cerebral Cortex; Cerebral He | 1974 |
Reserpine in experimental cerebral edema.
Topics: Animals; Brain Edema; Cerebral Cortex; Cold Temperature; Haplorhini; Periodic Acid; Reserpine; Serum | 1966 |
[Therapy of acute cerebrovascular insufficiency].
Topics: Anticoagulants; Brain Edema; Cardiac Glycosides; Cerebrovascular Disorders; Dextrans; Humans; Inject | 1972 |
Hypertensive encephalopathy.
Topics: Anxiety; Brain Diseases; Brain Edema; Coma; Diazoxide; Female; Furosemide; Glomerulonephritis; Heada | 1972 |
[Therapy of circulatory disorders of the brain and spinal cord].
Topics: Age Factors; Anticoagulants; Brain Edema; Cerebral Hemorrhage; Cerebrovascular Disorders; Coronary D | 1969 |