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reserpine and Brain Edema

reserpine has been researched along with Brain Edema in 10 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Research Excerpts

ExcerptRelevanceReference
"The effects of antihypertensive drugs, such as nifedipine, chlorpromazine, reserpine and thiopental on mean arterial blood pressure (ABP), mean intracranial pressure (ICP) and cerebral perfusion pressure (CPP) were studied in 43 patients with systemic hypertension and intracranial hypertension due to hemorrhagic cerebrovascular diseases and other causes."3.68Effects of antihypertensive drugs on intracranial hypertension. ( Handa, Y; Hayashi, M; Hirose, S; Kawano, H; Kobayashi, H; Nozaki, J, 1991)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BULLE, PH1
Hirose, S1
Handa, Y1
Kobayashi, H1
Kawano, H1
Nozaki, J1
Hayashi, M1
Philipp, T1
Nast, HP1
Clasen, RA2
Pandolfi, S2
Casey, D1
Laing, I1
Oelke, D1
Hass, GM1
Koch-Weser, J1
Berzewski, H1
Breslin, DJ1
Finnerty, FA1
Gottstein, U1

Reviews

2 reviews available for reserpine and Brain Edema

ArticleYear
Hypertensive emergencies.
    The New England journal of medicine, 1974, Jan-24, Volume: 290, Issue:4

    Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Coronary D

1974
Hypertensive crisis.
    The Medical clinics of North America, 1969, Volume: 53, Issue:2

    Topics: Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Diazoxide; Emergencies; Humans; Hyd

1969

Other Studies

8 other studies available for reserpine and Brain Edema

ArticleYear
Effects of reserpine and chlorpromazine in prevention of cerebral edema and reversible cell damage.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1957, Volume: 94, Issue:3

    Topics: Biomedical Research; Brain Edema; Chlorpromazine; Edema; Reserpine

1957
Effects of antihypertensive drugs on intracranial hypertension.
    Zentralblatt fur Neurochirurgie, 1991, Volume: 52, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Brain Edema; Cerebral Hemorrhage; Cerebrospina

1991
[Hypertensive emergencies].
    Der Internist, 1974, Volume: 15, Issue:3

    Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies;

1974
Reserpine in experimental cerebral edema: further observations.
    Neurology, 1974, Volume: 24, Issue:6

    Topics: Animals; Blood Pressure; Body Temperature; Brain Edema; Brain Injuries; Cerebral Cortex; Cerebral He

1974
Reserpine in experimental cerebral edema.
    Neurology, 1966, Volume: 16, Issue:12

    Topics: Animals; Brain Edema; Cerebral Cortex; Cold Temperature; Haplorhini; Periodic Acid; Reserpine; Serum

1966
[Therapy of acute cerebrovascular insufficiency].
    Deutsche medizinische Wochenschrift (1946), 1972, Dec-22, Volume: 97, Issue:51

    Topics: Anticoagulants; Brain Edema; Cardiac Glycosides; Cerebrovascular Disorders; Dextrans; Humans; Inject

1972
Hypertensive encephalopathy.
    The American journal of medicine, 1972, Volume: 52, Issue:5

    Topics: Anxiety; Brain Diseases; Brain Edema; Coma; Diazoxide; Female; Furosemide; Glomerulonephritis; Heada

1972
[Therapy of circulatory disorders of the brain and spinal cord].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Age Factors; Anticoagulants; Brain Edema; Cerebral Hemorrhage; Cerebrovascular Disorders; Coronary D

1969