reserpine has been researched along with Bradyarrhythmia in 42 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Activities of the compounds in antagonizing reserpine-induced ptosis in rabbits and prolongation of alcohol hypnosis in mice give good correlation with their clinical actions, whilst their activities in augmenting excitation of rats by amphetamine and yohimbine toxicity in mice, and in reversing reserpine-induced bradycardia in rats offer further evidence for drug-induced sensitization to adrenergic or tryptaminic mechanisms, which is not however specific for antidepressant agents." | 3.64 | A COMPARISON OF IMIPRAMINE, CHLORPROMAZINE AND RELATED DRUGS IN VARIOUS TESTS INVOLVING AUTONOMIC FUNCTIONS AND ANTAGONISM OF RESERPINE. ( HALLIWELL, G; QUINTON, RM; WILLIAMS, FE, 1964) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (90.48) | 18.7374 |
| 1990's | 2 (4.76) | 18.2507 |
| 2000's | 1 (2.38) | 29.6817 |
| 2010's | 1 (2.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gallo, E | 1 |
| Giocaliere, E | 1 |
| Benemei, S | 1 |
| Bilia, AR | 1 |
| Karioti, A | 1 |
| Pugi, A | 1 |
| di Pirro, M | 1 |
| Menniti-Ippolito, F | 1 |
| Pieraccini, G | 1 |
| Gori, L | 1 |
| Mugelli, A | 1 |
| Firenzuoli, F | 1 |
| Vannacci, A | 1 |
| SCHUMANN, H | 1 |
| ALBANO, T | 1 |
| MOTTA, R | 1 |
| ABBOUD, FM | 1 |
| ECKSTEIN, JW | 1 |
| FEKETE, M | 1 |
| BORSY, J | 1 |
| HALLIWELL, G | 1 |
| QUINTON, RM | 1 |
| WILLIAMS, FE | 1 |
| BRAY, GA | 1 |
| DUCHENE-MARULLAZ, P | 1 |
| VACHER, J | 1 |
| DELORT, P | 1 |
| MASSARO, GD | 1 |
| FINNERTY, FA | 1 |
| RYAN, M | 1 |
| SABATTINI, P | 1 |
| Lychkova, AE | 1 |
| Stephan, E | 1 |
| Nymark, M | 1 |
| Rasmussen, J | 1 |
| Paakkari, P | 1 |
| Paakkari, I | 1 |
| Karppanen, H | 1 |
| Paasonen, MK | 1 |
| McLemore, GL | 1 |
| Billingsley, ML | 1 |
| Severs, WB | 1 |
| Urthaler, F | 3 |
| James, TN | 3 |
| Isobe, JH | 2 |
| Jahr, JS | 1 |
| Weber, S | 1 |
| Schollmeyer, P | 1 |
| Golochevskaia, VS | 1 |
| Witzel, L | 1 |
| Soballa, G | 1 |
| Cheymol, G | 1 |
| Mouillé, P | 1 |
| Laubie, M | 1 |
| Schmitt, H | 1 |
| Fuccella, LM | 1 |
| Méhes, J | 1 |
| Decsi, L | 1 |
| Várszegi, MK | 1 |
| Hideg, H | 1 |
| Hankovszky, OH | 1 |
| Romero, T | 1 |
| Talesnik, J | 1 |
| Buterbaugh, GG | 1 |
| Spratt, JL | 1 |
| Jandhyala, BS | 1 |
| Clarke, DE | 1 |
| Buckley, JP | 1 |
| Gilmour, KE | 1 |
| Vander Ark, GD | 1 |
| Norton, LW | 1 |
| Pomerantz, M | 1 |
| Hoobler, SW | 1 |
| Sagastume, E | 1 |
| Barrera, F | 1 |
| Ascanio, G | 1 |
| Lautsch, EV | 1 |
| Oppenheimer, MJ | 1 |
| Ingenito, AJ | 1 |
| Barrett, JP | 1 |
| Procita, L | 1 |
| Usui, A | 1 |
| Makabe, T | 1 |
| Hashimoto, K | 1 |
| Suzuki, Y | 1 |
| Chiba, S | 1 |
| Toda, N | 1 |
| Kobinger, W | 1 |
| Walland, A | 1 |
| Rosenblum, I | 1 |
| Rosenblum, G | 1 |
| Marcus, SM | 1 |
| Borzelleca, JF | 1 |
| Ominsky, AJ | 1 |
| Wollman, H | 1 |
| Varma, DR | 1 |
| Fizel', A | 1 |
| Fizel'ová, A | 1 |
2 reviews available for reserpine and Bradyarrhythmia
| Article | Year |
|---|---|
[Side effects of anti-arrhythmic agents].
Topics: 1-Propanol; Adrenal Cortex Hormones; Agranulocytosis; Anorexia Nervosa; Anti-Arrhythmia Agents; Anti | 1971 |
Effects of prolonged administration of certain antihypertensive agents.
Topics: Adrenal Glands; Animals; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Bradycardia; Ca | 1974 |
2 trials available for reserpine and Bradyarrhythmia
| Article | Year |
|---|---|
Trasicor: review of the pharmacology and clinical results.
Topics: 1-Propanol; Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Animals; Arrhythmias, Cardiac | 1969 |
Clonidine hydrochloride in the treatment of hypertension.
Topics: Antihypertensive Agents; Bradycardia; Central Nervous System; Chlorides; Diuretics; Drug Synergism; | 1971 |
38 other studies available for reserpine and Bradyarrhythmia
| Article | Year |
|---|---|
Anything to declare? Possible risks for patients' health resulting from undeclared plants in herbal supplements.
Topics: Ajmaline; Anti-Arrhythmia Agents; Antihypertensive Agents; Bradycardia; Dietary Supplements; Drug Co | 2012 |
[Therapy of hemodynamic and coronary insufficiency of the heart].
Topics: Bradycardia; Coronary Artery Disease; Heart; Heart Failure; Hemodynamics; Humans; Reserpine | 1958 |
[Bradycardic action of reserpine].
Topics: Anti-Arrhythmia Agents; Bradycardia; Enzyme Inhibitors; Heart Diseases; Humans; Reserpine | 1958 |
EFFECTS OF SMALL ORAL DOSES OF RESERPINE ON VASCULAR RESPONSES TO TYRAMINE AND NOREPINEPHRINE IN MAN.
Topics: Blood Pressure; Blood Pressure Determination; Bradycardia; Norepinephrine; Pharmacology; Physiology; | 1964 |
ON THE ANTIARRHYTHMIC EFFECT OF SOME THYMOLEPTICS (AMITRIPTYLINE, IMIPRAMINE, TRIMEPROPIMINE AND DESMETHYLIMIPRAMINE).
Topics: Aconitum; Amitriptyline; Antidepressive Agents; Atrial Fibrillation; Bradycardia; Bretylium Compound | 1964 |
A COMPARISON OF IMIPRAMINE, CHLORPROMAZINE AND RELATED DRUGS IN VARIOUS TESTS INVOLVING AUTONOMIC FUNCTIONS AND ANTAGONISM OF RESERPINE.
Topics: Alcoholic Intoxication; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Autonomic Nervou | 1964 |
EFFECTS OF RESERPINE ON THYROIDECTOMIZED-ANDRENODEMEDULLATED RATS.
Topics: Adrenal Medulla; Basal Metabolism; Blood Glucose; Body Temperature; Bradycardia; Carbon Dioxide; Dia | 1964 |
[DOES RESERPINE POSSESS A BRADYCARDIC ACTION?].
Topics: Bradycardia; Dogs; Electrocardiography; Heart Rate; Pharmacology; Research; Reserpine | 1965 |
The effect of reserpine and digitalis on the heart rate during noradrenaline infusion.
Topics: Bradycardia; Digitalis; Heart Rate; Humans; Norepinephrine; Reserpine | 1960 |
[The bradycardic action of reserpine: some clinical applications].
Topics: Bradycardia; Reserpine; Tachycardia | 1960 |
Balance of activity of sympathetic, parasympathetic, and serotoninergic divisions of the autonomic nervous system in rabbits.
Topics: Aging; Animals; Autonomic Nervous System; Bradycardia; Catecholamines; Heart; Muscles; Myocardium; R | 2005 |
[Method of prolonged bradycardiac therapy of the heart by means of reserpine administration].
Topics: Adult; Bradycardia; Humans; Infant; Male; Reserpine | 1966 |
Effect of certain drugs upon amitriptyline induced electrocardiographic changes.
Topics: Acetylcholine; Amitriptyline; Animals; Atropine; Blood Pressure; Bradycardia; Bundle-Branch Block; E | 1966 |
Mechanisms of the inhibitory cardiovascular effects of taurine and homotaurine.
Topics: Animals; Atenolol; Atropine; Blood Pressure; Bradycardia; Depression, Chemical; Heart Rate; Hypotens | 1983 |
Cardiac noradrenergic mechanisms mediate GABA-enhanced ouabain cardiotoxicity.
Topics: Analysis of Variance; Animals; Bradycardia; Dose-Response Relationship, Drug; gamma-Aminobutyric Aci | 1994 |
A comparison of His bundle electrograms recorded from the aortic root and from a plaque sutured near the His bundle.
Topics: Acetylcholine; Animals; Aorta; Atropine; Bradycardia; Bundle of His; Cardiac Catheterization; Dogs; | 1975 |
Analysis of components in a cardiogenic hypertensive chemoreflex.
Topics: Animals; Atropine; Blood Pressure; Bradycardia; Cardiovascular System; Chemoreceptor Cells; Coronary | 1975 |
Ventricular dysrhythmias following an alfentanil anesthetic in a patient on reserpine for hypertension.
Topics: Alfentanil; Anesthesia, Intravenous; Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes, Premature | 1991 |
[Cardiac rhythm disorders. 2. Therapy].
Topics: Adrenergic alpha-Antagonists; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial F | 1971 |
[Treatment of arrhythmias].
Topics: Adrenergic beta-Antagonists; Ajmaline; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; | 1973 |
[Comparative study of chronotropic and inotropic effects of different beta adrenolytic drugs].
Topics: Acetanilides; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Bradycardia; Dogs; Drug Antagoni | 1972 |
Inhibitory effect of 1-alkylbenzimidazoles on gastric secretion in the rat.
Topics: Acetylcholine; Animals; Behavior, Animal; Blood Pressure; Bradycardia; Carbachol; Cats; Central Nerv | 1966 |
Influence of nicotine on the coronary circulation of the isolated heart of the cat.
Topics: Animals; Atropine; Bradycardia; Catecholamines; Cats; Coronary Vessels; Electric Stimulation; Electr | 1967 |
Observations on the possible role of central mechanisms in acute digitoxigenin toxicity.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Bradycardia; Cardanolides; Cats; Electrocardiography; | 1970 |
Morphine and autonomic control of the sinus node.
Topics: Animals; Atropine; Autonomic Nervous System; Bradycardia; Dogs; Heart Rate; Injections, Intravenous; | 1973 |
The effects of brain stem compression on the heart.
Topics: Animals; Arrhythmias, Cardiac; Atropine; Blood Pressure; Bradycardia; Brain Injuries; Brain Stem; Ca | 1974 |
Factors in acute hypotension and ventricular fibrillation after cardiac necrosis.
Topics: Animals; Atropine; Blood Pressure; Bradycardia; Catecholamines; Dogs; Dye Dilution Technique; Electr | 1967 |
Centrally mediated peripheral hypotensive effects of reserpine and hydralazine when perfused through the isolated in situ cat brain.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Bradycardia; Brain; Brain Chemistry; Carotid Sinus; Ca | 1969 |
[Influence of CaC12 and BaC12 on the ventricular pacemaker of the rabbit].
Topics: Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Barium; Bradycardia; Calcium; Calcium Chlori | 1969 |
[Influence of pentetrazol (PTZ), dimorpholamine (DMP) and trans-pi-oxocamphor (t-pi-oc) on the ventricular pacemaker of guinea pigs].
Topics: Amides; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Bradycardia; Camphor; Electrocardiog | 1969 |
Effect of potassium excess on pacemaker activity of canine sinoatrial node in vivo.
Topics: Acetylcholine; Animals; Atrial Fibrillation; Atropine; Blood Pressure; Bradycardia; Dogs; Female; He | 1970 |
Barium-induced automaticity in relation to calcium ions and norepinephrine in the rabbit left atrium.
Topics: Action Potentials; Animals; Atrial Function; Barium; Bradycardia; Calcium; Electric Stimulation; Evo | 1970 |
[Blood circulation studies with 2-(2,6-dichlorphenylamino)-2-imidazoline hydrochloride].
Topics: Animals; Antihypertensive Agents; Atropine; Blood Circulation; Blood Pressure; Bradycardia; Cardiac | 1967 |
Cardiovascular responses to cyclohexylamine.
Topics: Amines; Animals; Blood Pressure; Bradycardia; Cardiovascular System; Cats; Cocaine; Cyclohexanes; Fe | 1968 |
Observations on reserpine-induced bradycardia.
Topics: Animals; Atropine; Body Weight; Bradycardia; Carbon Dioxide; Cats; Diarrhea; Glucose; Heart Rate; He | 1968 |
Hazards of general anesthesia in the reserpinized patient.
Topics: Adolescent; Adult; Anesthesia, General; Anesthetics; Bradycardia; Catecholamines; Drug Synergism; Hu | 1969 |
Cholinergic transmission in the cat medulla oblongata in the initiation of vagal bradycardia.
Topics: Animals; Atropine; Blood Pressure; Bradycardia; Cats; Electric Stimulation; Female; Hexamethonium Co | 1966 |
[Experimental studies of some metabolic processes of the failing heart. IX. Participation of the cholinergic mechanism in the radiographic, electrocardiographic and metabolic changes in the course of chronic constriction of the aorta, and after applicatio
Topics: Acetylcholine; Animals; Aorta; Bradycardia; Cholinesterase Inhibitors; Diphtheria Toxin; Glycogen; H | 1966 |