reserpine has been researched along with Blepharoptosis in 100 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Blepharoptosis: Drooping of the upper lid due to deficient development or paralysis of the levator palpebrae muscle.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Subsequently, ptosis and hypothermia induced by reserpine were assessed." | 3.83 | Antidepressant-like effects of the Radix Bupleuri and Radix Paeoniae Alba drug pair. ( Gao, S; Gao, SM; Li, R; Wang, Y; Yu, CQ; Zhang, M, 2016) |
| " A possible mechanism was explored in the test of antagonism of reserpine-induced ptosis and hypothermia in mice." | 3.76 | Antidepressant-like effect of genipin in mice. ( Chi, W; Cui, YL; Dong, TJ; Gao, S; Hu, LM; Liu, LP; Tian, JS, 2010) |
| " Therefore, the aim of this study was to compare the effects of the racemic pirlindole (a selective and reversible MAO-A inhibitor) and its two enantiomers using biochemical techniques (in vitro and ex vivo determination of rat brain MAO-A and MAO-B activity) and behavioural models (forced swimming test and reserpine-induced hypothermia and palpebral ptosis test)." | 3.70 | Comparative study of pirlindole, a selective RIMA, and its two enantiomers using biochemical and behavioural techniques. ( Bruhwyler, J; Chleide, E; Damas, J; de Tullio, P; Decamp, E; Delarge, J; Dresse, A; Géczy, J; Gérardy, J; Lejeune, C; Liégeois, JF, 1998) |
| " Lortalamine antagonises in a dose-related manner reserpine-induced ptosis and hypothermia, and is far more potent than imipramine in this regard." | 3.67 | Pharmacology of lortalamine, a new potent non-tricyclic antidepressant. ( Berthelon, JJ; Betbeder-Matibet, A; Bonhomme, Y; Depin, JC; Muller, AJ, 1985) |
| " Proadifen antagonized the action of IMI when investigated in reserpine hypothermia and ptosis and in the behavioral despair test." | 3.66 | Influence of proadifen, an inhibitor of the metabolism of drugs, on the action of imipramine and desipramine in rats. ( Daniel, W; Maj, J; Rogóz, Z; Skuza, G; Sowińska, H, 1981) |
| "The reserpine-treated animal may be useful for the research of not only fibromyalgia syndrome but also FSS, especially for the research focusing on the hypothesis that FSS is associated with the disturbance of endogenous monoamine system." | 1.48 | Monoamine system disruption induces functional somatic syndromes associated symptomatology in mice. ( Azuma, R; Kawasaki, S; Miwa, M; Murai, S; Nagakura, Y; Ohsaka, N; Saito, H; Takahashi, S; Takebayashi, Y, 2018) |
| "Tramadol is a centrally acting analgesic that demonstrates opioid and monoaminergic properties." | 1.32 | Antidepressant-like effect of tramadol and its enantiomers in reserpinized mice: comparative study with desipramine, fluvoxamine, venlafaxine and opiates. ( Berrocoso, E; Gibert-Rahola, J; Micó, JA; Rojas-Corrales, MO, 2004) |
| "Sibutramine HCl is an inhibitor of the reuptake of monoamines with a pharmacological profile in rodents indicative of antidepressant activity." | 1.28 | The contribution of metabolites to the rapid and potent down-regulation of rat cortical beta-adrenoceptors by the putative antidepressant sibutramine hydrochloride. ( Buckett, WR; Hopcroft, RH; Luscombe, GP; Thomas, PC, 1989) |
| "Tianeptine is an antidepressant characterized by a 3-chlorodibenzothiazepin nucleus and an aminoheptanoic side chain." | 1.27 | Structure-activity relationships of tricyclic antidepressants, with special reference to tianeptine. ( Kamoun, A; Labrid, C; Malen, C; Mocaër, E; Moleyre, J; Poignant, JC, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 83 (83.00) | 18.7374 |
| 1990's | 8 (8.00) | 18.2507 |
| 2000's | 5 (5.00) | 29.6817 |
| 2010's | 4 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nagakura, Y | 1 |
| Ohsaka, N | 1 |
| Azuma, R | 1 |
| Takahashi, S | 1 |
| Takebayashi, Y | 1 |
| Kawasaki, S | 1 |
| Murai, S | 1 |
| Miwa, M | 1 |
| Saito, H | 1 |
| Liu, X | 1 |
| Liu, F | 1 |
| Yue, R | 1 |
| Li, Y | 1 |
| Zhang, J | 1 |
| Wang, S | 1 |
| Zhang, S | 1 |
| Wang, R | 1 |
| Shan, L | 1 |
| Zhang, W | 1 |
| Wang, Y | 1 |
| Gao, SM | 1 |
| Li, R | 1 |
| Zhang, M | 1 |
| Gao, S | 2 |
| Yu, CQ | 1 |
| Mao, Q | 1 |
| Huang, Z | 1 |
| Ip, S | 1 |
| Che, C | 1 |
| Mao, QQ | 1 |
| Ip, SP | 1 |
| Tsai, SH | 1 |
| Che, CT | 1 |
| Tian, JS | 1 |
| Cui, YL | 1 |
| Hu, LM | 1 |
| Chi, W | 1 |
| Dong, TJ | 1 |
| Liu, LP | 1 |
| Finberg, JP | 1 |
| Youdim, MB | 1 |
| GARATTINI, S | 1 |
| GIACHETTI, A | 1 |
| PIERI, L | 1 |
| RE, R | 1 |
| FIELDEN, R | 3 |
| GREEN, AL | 3 |
| ACETO, MD | 4 |
| HARRIS, LS | 1 |
| MALONE, MH | 4 |
| ROTH, RH | 1 |
| Rojas-Corrales, MO | 1 |
| Berrocoso, E | 1 |
| Gibert-Rahola, J | 1 |
| Micó, JA | 1 |
| Tedeschi, DH | 3 |
| Fowler, PJ | 2 |
| Fujita, T | 1 |
| Miller, RB | 1 |
| Deniard, MJ | 1 |
| Meignen, J | 1 |
| DeFeudis, FV | 1 |
| Balsara, JJ | 1 |
| Gada, VP | 1 |
| Nandal, NV | 1 |
| Chandorkar, AG | 1 |
| Poncelet, M | 3 |
| Hakkou, F | 1 |
| Simon, P | 4 |
| Bourin, M | 1 |
| Chermat, R | 3 |
| Vaccari, A | 1 |
| Biassoni, R | 1 |
| Namba, MM | 1 |
| Quock, RM | 1 |
| Zapatero, J | 1 |
| Basi, N | 1 |
| Vilageliu, J | 1 |
| Sanfeliu, C | 1 |
| Bruseghini, L | 1 |
| Maj, J | 2 |
| Daniel, W | 1 |
| Rogóz, Z | 2 |
| Skuza, G | 2 |
| Sowińska, H | 1 |
| Castanier, L | 1 |
| Rubat, C | 2 |
| Coudert, P | 2 |
| Albuisson, E | 1 |
| Chopineau, J | 1 |
| Couquelet, J | 1 |
| Bastide, P | 1 |
| Tronche, P | 1 |
| Subarnas, A | 1 |
| Tadano, T | 1 |
| Oshima, Y | 1 |
| Kisara, K | 2 |
| Ohizumi, Y | 1 |
| Nakagawa, T | 1 |
| Ukai, K | 1 |
| Kubo, S | 1 |
| Abrahams, TP | 1 |
| Faust, ML | 1 |
| Varner, KJ | 1 |
| Bruhwyler, J | 1 |
| Liégeois, JF | 1 |
| Gérardy, J | 1 |
| Damas, J | 1 |
| Chleide, E | 1 |
| Lejeune, C | 1 |
| Decamp, E | 1 |
| de Tullio, P | 1 |
| Delarge, J | 1 |
| Dresse, A | 1 |
| Géczy, J | 1 |
| Almeida, RN | 1 |
| Navarro, DS | 1 |
| de Assis, TS | 1 |
| de Medeiros, IA | 1 |
| Thomas, G | 1 |
| El Yacoubi, M | 1 |
| Ledent, C | 1 |
| Parmentier, M | 1 |
| Bertorelli, R | 1 |
| Ongini, E | 1 |
| Costentin, J | 1 |
| Vaugeois, JM | 1 |
| Shika, K | 1 |
| Nakata, C | 1 |
| Ogura, M | 1 |
| Tamada, T | 1 |
| Fujimoto, Y | 1 |
| Mooradian, A | 1 |
| Dupont, PE | 1 |
| Hlavec, AG | 1 |
| Pearl, J | 1 |
| Oono, S | 1 |
| Uga, S | 1 |
| David, J | 1 |
| Kaul, CL | 1 |
| Grewal, RS | 1 |
| Fukushima, H | 2 |
| Nakamura, M | 3 |
| Yamamoto, H | 1 |
| Asselin, AA | 1 |
| Humber, LG | 3 |
| Komlossy, J | 1 |
| Hsu, SY | 1 |
| Huang, CL | 1 |
| Waters, IW | 1 |
| Demerson, CA | 2 |
| Santroch, G | 1 |
| Sofia, RD | 1 |
| Harakal, JJ | 1 |
| Shoji, T | 1 |
| Sakurada, S | 1 |
| Doggett, NS | 1 |
| Case, G | 1 |
| Fuentes, JA | 1 |
| Neff, NH | 1 |
| Toscano, L | 1 |
| Grisanti, G | 1 |
| Fioriello, G | 1 |
| Seghetti, E | 1 |
| Bianchetti, A | 1 |
| Bossoni, G | 1 |
| Riva, M | 1 |
| Boissier, JR | 1 |
| Heal, DJ | 1 |
| Frankland, AT | 1 |
| Gosden, J | 1 |
| Hutchins, LJ | 1 |
| Prow, MR | 1 |
| Luscombe, GP | 3 |
| Buckett, WR | 3 |
| Hopcroft, RH | 1 |
| Thomas, PC | 2 |
| Brochet, D | 1 |
| Kato, T | 1 |
| Katsuyama, M | 1 |
| Karai, N | 1 |
| Hirose, A | 1 |
| Katsube, J | 1 |
| Labrid, C | 1 |
| Moleyre, J | 1 |
| Poignant, JC | 1 |
| Malen, C | 1 |
| Mocaër, E | 1 |
| Kamoun, A | 1 |
| Michaluk, J | 1 |
| Rawłów, A | 1 |
| Baizman, ER | 1 |
| Ezrin, AM | 1 |
| Ferrari, RA | 1 |
| Luttinger, D | 1 |
| Balsamo, A | 1 |
| Giorgi, I | 1 |
| Lapucci, A | 1 |
| Lucacchini, A | 1 |
| Macchia, B | 1 |
| Macchia, F | 1 |
| Martini, C | 1 |
| Rossi, A | 1 |
| Burak, K | 1 |
| Lipnicka, U | 1 |
| Orszańska, H | 1 |
| Rykowski, Z | 1 |
| Witkiewicz, K | 1 |
| Wrzesień, J | 1 |
| Bogdal, M | 1 |
| Krzywasiński, L | 1 |
| Borkowska, B | 1 |
| McCarthy, JR | 1 |
| Wright, DL | 1 |
| Schuster, AJ | 1 |
| Abdallah, AH | 1 |
| Shea, PJ | 1 |
| Eyster, R | 1 |
| Depin, JC | 1 |
| Betbeder-Matibet, A | 1 |
| Bonhomme, Y | 1 |
| Muller, AJ | 1 |
| Berthelon, JJ | 1 |
| Schmidt, G | 2 |
| Kusel, HJ | 2 |
| Dal Ri, H | 1 |
| Cockrill, S | 1 |
| Somerville, AR | 1 |
| Whittle, BA | 1 |
| Menon, MK | 1 |
| Dandiya, PC | 1 |
| Barnett, A | 1 |
| Taber, RI | 1 |
| Roth, FE | 1 |
| Gluckman, MI | 1 |
| Baum, T | 1 |
| Srimal, RC | 1 |
| Singh, HK | 1 |
| Dhawan, BN | 1 |
| Cotillo, P | 1 |
| Bonaccorsi, A | 1 |
| Philipp, AH | 1 |
| Kraml, MJ | 1 |
| Charest, MP | 1 |
| Tom, H | 1 |
| Vávra, I | 1 |
| Boshek, RL | 1 |
| Boston, JE | 1 |
| Brossi, A | 1 |
| Pool, W | 1 |
| Sheppard, H | 2 |
| Burns, JJ | 1 |
| Kaiser, A | 1 |
| Bigler, R | 1 |
| Bartholini, G | 1 |
| Pletscher, A | 1 |
| Fanelli, O | 1 |
| Mazzoncini, V | 1 |
| Trallori, L | 1 |
| Ueki, S | 1 |
| Ogawa, N | 1 |
| Watanabe, S | 1 |
| Gomita, Y | 1 |
| Araki, Y | 1 |
| Trepanier, DL | 1 |
| Sunder, S | 1 |
| Monkovic, I | 1 |
| Perron, YG | 1 |
| Martel, R | 1 |
| Simpson, WJ | 1 |
| Horst, WD | 1 |
| Pool, WR | 2 |
| Spiegel, HE | 1 |
| Daum, SJ | 2 |
| Clarke, RL | 2 |
| Matier, WL | 1 |
| Owens, DA | 1 |
| Comer, WT | 1 |
| Deitchman, D | 1 |
| Ferguson, HC | 1 |
| Seidehamel, RJ | 1 |
| Young, JR | 1 |
| Taha, AM | 1 |
| Omar, NM | 1 |
| Bayomi, SM | 1 |
| Ammar, EM | 1 |
| Afifi, A | 1 |
| Borgman, RJ | 1 |
| Baylor, MR | 1 |
| McPhillips, JJ | 1 |
| Stitzel, RE | 1 |
| Felix, AM | 1 |
| Winter, DP | 1 |
| Wang, SS | 1 |
| Kulesha, ID | 1 |
| Hane, DL | 1 |
| Gambino, AJ | 1 |
| Kaiser, C | 1 |
| Pavloff, AM | 1 |
| Garvey, E | 1 |
| Zirkle, CL | 1 |
| Nodiff, EA | 1 |
| Saggiomo, AJ | 1 |
| Reed, FD | 1 |
| Brown, RG | 1 |
| Delgado, JN | 1 |
| Isaacson, EI | 1 |
| Lapin, IP | 1 |
| Osipova, SV | 1 |
| Uskova, NV | 1 |
| Stabrovski, EM | 1 |
| Stoll, RG | 2 |
| Bates, TR | 2 |
| Nieforth, KA | 3 |
| Swarbrick, J | 1 |
| Lotti, VJ | 1 |
| Porter, CC | 1 |
| Rohte, O | 1 |
| Dhawan, KN | 1 |
| Jaju, BP | 1 |
| Gupta, GP | 1 |
| Leszkovszky, GP | 1 |
| Tardos, L | 1 |
| Lendvai, J | 1 |
| Takács, K | 1 |
| Veldkamp, W | 1 |
| Johnson, GA | 1 |
| Keasling, HH | 1 |
| Gibaldi, M | 1 |
| Feldman, S | 1 |
| Bernardi, L | 1 |
| Coda, S | 1 |
| Pegrassi, L | 1 |
| Suchowsky, GK | 1 |
| Faith, ME | 1 |
| Young, LD | 1 |
| Grabarits, F | 1 |
| Harvey, JA | 1 |
| Nematollahi, J | 3 |
| Nulu, JR | 2 |
| Weinstock, M | 1 |
| Marshall, AS | 1 |
| Decato, L | 1 |
| Burger, A | 1 |
| Siuda, JF | 1 |
| Hochman, HI | 1 |
| Guess, W | 1 |
| Autian, J | 1 |
| Huebner, CF | 1 |
| Donoghue, EM | 1 |
| Plummer, AJ | 1 |
| Furness, PA | 1 |
100 other studies available for reserpine and Blepharoptosis
| Article | Year |
|---|---|
Monoamine system disruption induces functional somatic syndromes associated symptomatology in mice.
Topics: Animals; Biogenic Monoamines; Blepharoptosis; Body Temperature; Body Weight; Central Nervous System; | 2018 |
The antidepressant-like effect of bacopaside I: possible involvement of the oxidative stress system and the noradrenergic system.
Topics: Administration, Oral; Animals; Antidepressive Agents; Blepharoptosis; Catalase; Dose-Response Relati | 2013 |
Antidepressant-like effects of the Radix Bupleuri and Radix Paeoniae Alba drug pair.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Blepharoptosis; Brain; Bupleu | 2016 |
Antidepressant-like effect of ethanol extract from Paeonia lactiflora in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Blepharoptosis; Clomipramine; Depression; Dise | 2008 |
Antidepressant-like effect of peony glycosides in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Blepharoptosis; Cerebrum; Depression; Disease Mode | 2008 |
Antidepressant-like effect of genipin in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Blepharoptosis; Depression; D | 2010 |
Pharmacological properties of the anti-Parkinson drug rasagiline; modification of endogenous brain amines, reserpine reversal, serotonergic and dopaminergic behaviours.
Topics: Animals; Antiparkinson Agents; Biogenic Amines; Blepharoptosis; Brain; Dopamine; Dose-Response Relat | 2002 |
Antagonists of reserpine induced eyelid ptosis.
Topics: Blepharoptosis; Eyelid Diseases; Humans; Reserpine | 1960 |
VALIDITY OF PTOSIS AS A MEASURE OF THE CENTRAL DEPRESSANT ACTION OF RESERPINE.
Topics: Blepharoptosis; Brain Chemistry; Bretylium Compounds; Central Nervous System; Eyelids; Mice; Myocard | 1965 |
EFFECT OF VARIOUS AGENTS ON RESERPINE-INDUCED BLEPHAROPTOSIS.
Topics: Anti-Allergic Agents; Atropine; Blepharoptosis; Chlorpromazine; Eyelids; Histamine H1 Antagonists; I | 1965 |
Yohimbine potentiation of reserpine blepharoptosis.
Topics: Blepharoptosis; Eyelids; Reserpine; Yoga; Yohimbine | 1962 |
Antidepressant-like effect of tramadol and its enantiomers in reserpinized mice: comparative study with desipramine, fluvoxamine, venlafaxine and opiates.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Cyclohexanols; | 2004 |
Mechanisms underlying reserpine-induced ptosis and blepharospasm: evidence that reserpine decreases central sympathetic outflow in rats.
Topics: Animals; Blepharoptosis; Central Nervous System; Facial Nerve; Male; Norepinephrine; Rats; Reserpine | 1967 |
A comparative study of the noradrenaline-depleting and sympathetic-blocking actions of guanethidine and (-)-beta-hydroxyphenethylguanidine.
Topics: Amphetamine; Animals; Blepharoptosis; Blood Pressure; Cats; Drug Antagonism; Electric Stimulation; G | 1967 |
Reversal of reserpine-induced ptosis in the mouse by alpha-adrenoceptor-agonists.
Topics: Adrenergic alpha-Agonists; Animals; Blepharoptosis; Dose-Response Relationship, Drug; Male; Muridae; | 1983 |
Psychopharmacological investigation of the monoamine oxidase inhibitory activity of molindone, a dihydroindolone neuroleptic.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Behavior, Animal; Blepharoptosis; Catalepsy; Fenclonine; | 1984 |
Psychopharmacological profile of diphenylhydantoin in mice.
Topics: Animals; Apomorphine; Barbital; Behavior, Animal; Blepharoptosis; Drug Interactions; Male; Mice; Mot | 1984 |
The value of the reserpine test in psychopharmacology.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Drug Evaluation, Preclinical; Male | 1983 |
Gonadal influences on the inhibition of monoamine oxidase type B activity.
Topics: Animals; Blepharoptosis; Body Temperature; Estradiol; Female; Hypothalamus; Male; Monoamine Oxidase; | 1982 |
Effects of narcotic antagonists on L-dopa reversal of reserpine-induced catalepsy and blepharoptosis in mice.
Topics: Animals; Blepharoptosis; Catalepsy; Drug Antagonism; Drug Synergism; Humans; Kinetics; Levodopa; Mal | 1981 |
Toxicological studies of plafibride. Part 4: Interaction of plafibride with other drugs.
Topics: Animals; Blepharoptosis; Blood Pressure; Body Temperature; Clofibrate; Clofibric Acid; Dogs; Drug In | 1981 |
Influence of proadifen, an inhibitor of the metabolism of drugs, on the action of imipramine and desipramine in rats.
Topics: Animals; Blepharoptosis; Desipramine; Hypothermia; Imipramine; Male; Motor Activity; Proadifen; Rats | 1981 |
Synthesis of new serotonergic 2-substituted 4,6-diaryl pyridazin-3-ones.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Blepharoptosis; Chemical Phenomena; Chemistry, Physi | 1995 |
Behavioural profile of two potential antidepressant pyridazine derivatives including arylpiperazinyl moieties in their structure, in mice.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Bleph | 1995 |
Pharmacological properties of beta-amyrin palmitate, a novel centrally acting compound, isolated from Lobelia inflata leaves.
Topics: Animals; Antidepressive Agents; Apomorphine; Blepharoptosis; Catalepsy; Central Nervous System; Dose | 1993 |
Antidepressive effects of the stereoisomer cis-dosulepin hydrochloride.
Topics: Acetylcholine; Animals; Antidepressive Agents; Apomorphine; Blepharoptosis; Body Temperature; Brain | 1993 |
The depletion of monoamines blocks the sympathoinhibitory response to cocaine.
Topics: Adjuvants, Anesthesia; Adrenergic Fibers; alpha-Methyltyrosine; Animals; Biogenic Monoamines; Blepha | 1996 |
Comparative study of pirlindole, a selective RIMA, and its two enantiomers using biochemical and behavioural techniques.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Carbazoles; Female; Hypothermia; Mice; Monoam | 1998 |
Antidepressant effect of an ethanolic extract of the leaves of Cissampelos sympodialis in rats and mice.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Blepharoptosis; | 1998 |
Adenosine A2A receptor antagonists are potential antidepressants: evidence based on pharmacology and A2A receptor knockout mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Blepharoptosis; Disease Models, Animal; Dopamine A | 2001 |
[Inhibitory effects of methyl o-(4-hydroxy-3-methoxycinnamoyl) reserpate (CD-3400) on the central nervous system (author's transl)].
Topics: Agonistic Behavior; Animals; Avoidance Learning; Blepharoptosis; Body Temperature; Cats; Central Ner | 1977 |
3-Aminotetrahydrocarbazoles as a new series of central nervous system agents.
Topics: Amphetamine; Animals; Apomorphine; Blepharoptosis; Carbazoles; Central Nervous System; Haplorhini; H | 1977 |
[Two cases of bilateral Horner's syndrome induced by long-term use of the adrenergic neuron blocking agents (author's transl)].
Topics: Aged; Blepharoptosis; Female; Horner Syndrome; Humans; Methyldopa; Prenylamine; Reserpine | 1979 |
Pharmacological & biochemical characterization of antiparkinson drugs in reserpinized mice.
Topics: Animals; Antiparkinson Agents; Ataxia; Blepharoptosis; Catatonia; Disease Models, Animal; Humans; Ma | 1979 |
Pharmacology of 9-gamma-methylaminopropyl-9,10-dihydro-9,10-methanoanthracene-HCl (ID-9206-HCl), a new potent antidepressant.
Topics: Acetylcholine; Animals; Anthracenes; Antidepressive Agents, Tricyclic; Blepharoptosis; Body Temperat | 1977 |
Cycloalkanoindoles. 2. 1-Alkyl-1,2,3,4-tetrahydrocarbazole-1-ethanamines and related compounds. Potential antidepressants.
Topics: Animals; Antidepressive Agents, Tricyclic; Blepharoptosis; Carbazoles; Ethylamines; Indoles; Lethal | 1976 |
The effect of tricyclic antidepressants and neuroleptics on the peripheral and central action of norepinephrine in reserpine-treated mice.
Topics: Animals; Antidepressive Agents, Tricyclic; Blepharoptosis; Drug Synergism; Male; Mice; Mice, Inbred | 1976 |
Effect of acylation with eleostearic acids on the monoamine oxidase inhibitory potency of some hydrazine antidepressants in mice.
Topics: Acylation; Animals; Antidepressive Agents; Behavior, Animal; Blepharoptosis; Brain; Brain Chemistry; | 1975 |
3,4-Dihydro-1H-1,4-oxazino[4,3-a]indoles as potential antidepressants.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Indoles; Lethal Dose 50; Mice; Oxazines; Reserpine | 1975 |
Evaluation of ketamine HCl for anti-depressant activity.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Drug Synergism; Imipramine; Ketami | 1975 |
[Effect of beta-phenylethylamine derivatives on the central nervous system. III. Motor activity changes in mice due to the intracerebral administration of metaraminol].
Topics: Animals; Blepharoptosis; Brain; Catalepsy; Dopamine; Humans; Hydroxydopamines; Injections, Intravent | 1975 |
Some observations on the interaction between cardiac glycosides and reserpine in the heart and central nervous system.
Topics: Animals; Blepharoptosis; Body Temperature; Brain; Cardiac Glycosides; Catalepsy; Depression, Chemica | 1975 |
Selective monoamine oxidase inhibitor drugs as aids in evaluating the role of type A and B enzymes.
Topics: Animals; Blepharoptosis; Body Temperature; Clorgyline; Cyclopropanes; Harmaline; In Vitro Techniques | 1975 |
Basic derivatives of 6,7-dihydroindolo(1,7-ab)(1) benzazepine and 6H-indolo(7,1-cd)(1,5) benzoxazepine as potential antidepressant agents.
Topics: Animals; Antidepressive Agents; Benzazepines; Blepharoptosis; Body Temperature; Depression, Chemical | 1976 |
Interaction of atropine or methylatropinium with four effects of two cholinergic drugs.
Topics: Animals; Atropine; Atropine Derivatives; Blepharoptosis; Drug Interactions; Ganglionic Stimulants; M | 1976 |
A comparison of the effects of sibutramine hydrochloride, bupropion and methamphetamine on dopaminergic function: evidence that dopamine is not a pharmacological target for sibutramine.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain Chemistry; Bupropion; Chromatography, High Pre | 1992 |
The contribution of metabolites to the rapid and potent down-regulation of rat cortical beta-adrenoceptors by the putative antidepressant sibutramine hydrochloride.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Cerebral Cortex; Cyclobutanes; Dopamine; Hypothermia | 1989 |
The pharmacology of sibutramine hydrochloride (BTS 54 524), a new antidepressant which induces rapid noradrenergic down-regulation.
Topics: Adenylyl Cyclases; Animals; Antidepressive Agents, Tricyclic; Blepharoptosis; Body Temperature Regul | 1988 |
Antidepressant-like effects of diphenylhydantoin in mice: involvement of alpha-adrenoceptors.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Helplessness, Learned; In Vitro Techniques; Male; Mi | 1986 |
Reversal of the reserpine-induced ptosis by L-threo-3,4-dihydroxy-phenylserine (L-threo-DOPS), a (-)-norepinephrine precursor, and its potentiation by imipramine or nialamide.
Topics: Animals; Blepharoptosis; Brain Chemistry; Droxidopa; Drug Synergism; Imipramine; Injections, Intrave | 1986 |
Structure-activity relationships of tricyclic antidepressants, with special reference to tianeptine.
Topics: Animals; Antidepressive Agents, Tricyclic; Blepharoptosis; Male; Mice; Mice, Inbred Strains; Reserpi | 1988 |
Central action of the antidepressant drug pirlindole.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Carbazoles; C | 1986 |
Pharmacologic profile of fezolamine fumarate: a nontricyclic antidepressant in animal models.
Topics: Animals; Antidepressive Agents; Biological Transport; Blepharoptosis; Brain; Depression; Disease Mod | 1987 |
3-[(2-ethoxyphenoxy)methyl]piperidine derivatives. Synthesis and antidepressant activity.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Desipramine; Dopamine; Drug Evaluation, Precl | 1987 |
Synthesis of new arylanalogs of ketamine.
Topics: Amphetamine; Analgesics; Animals; Anticonvulsants; Behavior, Animal; Blepharoptosis; Body Temperatur | 1985 |
New bicyclic antidepressant agent. Synthesis and activity of napactadine and related compounds.
Topics: Aggression; Amidines; Animals; Blepharoptosis; Cerebral Cortex; Chemical Phenomena; Chemistry; Depre | 1985 |
Pharmacology of lortalamine, a new potent non-tricyclic antidepressant.
Topics: Amphetamine; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Benzopyrans; Biogenic Amin | 1985 |
[On the central and peripheral component with respect to the genesis of reserpine ptosis].
Topics: Animals; Blepharoptosis; Cats; Central Nervous System; Cocaine; Eyelids; Muscle, Smooth; Neuromuscul | 1967 |
The action of antidepressants on the uptake of 5-HT by platelets; a comparison with other tests for antidepressant activity.
Topics: Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Blepharoptosis; Blood Platelets; Imipram | 1968 |
[Effect of reserpine on sympathetic-motor innervation of the eye].
Topics: Action Potentials; Animals; Blepharoptosis; Cats; Cocaine; Eyelids; Motor Neurons; Neuromuscular Jun | 1968 |
A comparison of aralkylamines and aralkylguanidines as antagonists of adrenergic neurone blockade.
Topics: Amines; Amphetamine; Animals; Blepharoptosis; Cats; Chlorpromazine; Choline; Drug Antagonism; Electr | 1966 |
The mechanism of the tranquillizing action of asarone from Acorus calamus Linn.
Topics: Animals; Behavior, Animal; Blepharoptosis; Body Temperature; Brain Chemistry; Conditioning, Classica | 1967 |
Activity of antihistamines in laboratory antidepressant tests.
Topics: Amitriptyline; Animals; Anxiety; Blepharoptosis; Cyproheptadine; Drug Synergism; Histamine H1 Antago | 1969 |
The pharmacology of iprindole, a new antidepressant.
Topics: Acetylcholine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Appetite; Atropine; Bleph | 1969 |
Experimental evidence for imipramine like activity of fenfluramine.
Topics: Animals; Avoidance Learning; Blepharoptosis; Blood Pressure; Body Temperature; Cats; Columbidae; Dru | 1970 |
Observations on the interactions between desipramine and reserpine on adrenergic transmission in the rat.
Topics: Animals; Blepharoptosis; Desipramine; Electric Stimulation; Eyelids; Rats; Reserpine; Sympathetic Ne | 1972 |
Pyrrolo(4,3,2-de)isoquinolines with central nervous system and antihypertensive activities.
Topics: Animals; Antihypertensive Agents; Blepharoptosis; Blood Pressure; Brain; Central Nervous System; Dos | 1974 |
Proceedings: Ptosis as a model of depression.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Depression; Disease Models, Animal; Humans; Imiprami | 1974 |
L-DOPA: chemical modifications and biological evaluation.
Topics: Animals; Antiparkinson Agents; Blepharoptosis; Catatonia; Disease Models, Animal; Humans; Hypothermi | 1974 |
Antagonism of psychostimulant 2-phenyl-5,5-dimethyl-tetrahydro-1,4-oxazine hydrochloride (G 130) to central nervous system depressing drugs. Monoamine oxidase inhibitory activity and norepinephrine and serotonin induced changes. Comparison with dL-ampheta
Topics: Amphetamine; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Brain Stem; Chlorprom | 1974 |
[Psychopharmacological effects of doxepin hydrochloride].
Topics: Amitriptyline; Amphetamine; Animals; Behavior, Animal; Blepharoptosis; Body Temperature; Brain Chemi | 1972 |
3,4-Dihydroisocarbostyril and 1,2,3,4-tetrahydroisoquinoline derivatives of ephedrine.
Topics: Amphetamine; Animals; Behavior, Animal; Blepharoptosis; Central Nervous System; Drug Synergism; Ephe | 1973 |
Substituted tetrahydrofurfurylamines as potential antidepressants.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Blepharoptosis; Central Nervous System; Desipramin | 1973 |
Correlation between brain dopamine levels and 1-dopa activity in anti-Parkinson tests.
Topics: Animals; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Blepharoptosis; Brain; | 1973 |
Compounds affecting the central nervous system. 3. 3 -Phenyltropan-2-ols.
Topics: Acylation; Animals; Behavior, Animal; Blepharoptosis; Central Nervous System; Cocaine; Mice; Rats; R | 1973 |
Antihypertensive agents. Synthesis and biological properties of 2-amino-4-aryl-2-imidazolines.
Topics: Amines; Animals; Antihypertensive Agents; Blepharoptosis; Blood Pressure; Dogs; Guinea Pigs; Imidazo | 1973 |
Synthesis and screening of cyclic benzylhydrazine congeners as antidepressants.
Topics: Amphetamine; Animals; Antidepressive Agents; Benzyl Compounds; Blepharoptosis; Chemical Phenomena; C | 1974 |
Alpha-methyldopamine derivatives. Synthesis and pharmacology.
Topics: Animals; Apomorphine; Blepharoptosis; Body Temperature; Depression, Chemical; Dihydroxyphenylalanine | 1974 |
Synthesis and antireserpine activity of peptides of L-dopa.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Blepharoptosis; Catatonia; Dihydroxyphenylalanine; | 1974 |
Compounds affecting the central nervous system. 2. Aromatic acetals of tropanediols.
Topics: Acetals; Animals; Behavior, Animal; Blepharoptosis; Central Nervous System; Chromatography, Thin Lay | 1972 |
Analogs of phenothiazines. 4. Effect of structure upon neuropharmacological activity of some chlorpromazine analogs of the diphenylmethane type.
Topics: Aggression; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Benzyl Compounds; Blepharopt | 1972 |
Synthesis of 2-diphenylmethylene-1-acyl-1-alkyl hydrazines as potential psychotropic agents.
Topics: Acylation; Alkylation; Animals; Antidepressive Agents; Benzene Derivatives; Blepharoptosis; Body Tem | 1972 |
Pharmacological effects of imipramine and desmethylimipramine in developing rats.
Topics: Age Factors; Animals; Animals, Newborn; Blepharoptosis; Brain Chemistry; Chlorpromazine; Desipramine | 1969 |
Some physical factors affecting the enhanced blepharoptotic activity of orally administered reserpine-cholanic acid coprecipitates.
Topics: Animals; Bile Acids and Salts; Blepharoptosis; Drug Synergism; Hydrogen-Ion Concentration; Mice; Res | 1969 |
Potentiation and inhbition of some central actions of L(-)-dopa by decarboxylase inhibitors.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Blepharoptosis; Brain; Brai | 1970 |
Observation of the grooming behaviour of reserpinized white mice as a method for investigating reserpine antagonism and synergism.
Topics: Administration, Oral; Animals; Antidepressive Agents; Blepharoptosis; Charcoal; Desipramine; Dextroa | 1970 |
Validity of antagonism of different effects of reserpine as test for anti-depressant activity.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Blepharoptosis; Conditioning, Psychological; Dru | 1970 |
[Pharmacology of diphenylalkyl-derivatives. IV. Pharmacology of a noradrenaline increasing effect of dephenylpropylamine-amine-derivatives].
Topics: Adrenalectomy; Amphetamine; Anesthetics, Local; Animals; Blepharoptosis; Blood Pressure; Cardiovascu | 1967 |
Studies on the effects of reserpine in mice as influenced by its diluent.
Topics: Amines; Animals; Appetite Depressants; Benzphetamine; Blepharoptosis; Brain; Citrates; Dextroampheta | 1968 |
Correlation of pharmacologic activity and dissolution rates of reserpine-desoxycholic acid dispersions.
Topics: Animals; Bile Acids and Salts; Blepharoptosis; Chemical Phenomena; Chemistry, Physical; Mice; Pharma | 1968 |
Pharmacological properties of some derivatives of 1,3-benzoxazine.
Topics: Acacia; Animals; Blepharoptosis; Body Temperature; Diarrhea; Gastrointestinal Motility; Mice; Oxazin | 1968 |
Differences in the duration of reserpine action in the rat depending on the measure employed.
Topics: Amines; Animals; Avoidance Learning; Blepharoptosis; Brain; Conditioning, Psychological; Depression, | 1968 |
Imidazolecarboxyhydrazides. II. Chemistry and biological evaluation.
Topics: Animals; Blepharoptosis; Body Temperature; Depression, Chemical; Dicarboxylic Acids; Drug Synergism; | 1969 |
The influence of the sympathetic nervous system on the action of drugs on the lens.
Topics: Animals; Blepharoptosis; Body Temperature; Cataract; Chlorpromazine; Female; Guanethidine; Imipramin | 1969 |
Bile acid enhancement of reserpine-induced blepharoptosis.
Topics: Animals; Bile Acids and Salts; Blepharoptosis; Mice; Reserpine; Solubility | 1969 |
o,o'-Disubstituted phenylcyclopropylamines.
Topics: Amphetamine; Animals; Blepharoptosis; Hexobarbital; Imipramine; Mice; Motor Activity; Propylamines; | 1969 |
Imidazolecarbohydrazides. 3. Chemistry and biological evaluation.
Topics: Animals; Blepharoptosis; Body Temperature Regulation; Chemical Phenomena; Chemistry; Hydrazines; Hyp | 1969 |
Desoxycholic acid enhancement of orally administered reserpine.
Topics: Absorption; Animals; Bile Acids and Salts; Blepharoptosis; Drug Synergism; Mice; Reserpine | 1966 |
Imidazolecarboxhydrazides. I. Chemistry and biological evaluation.
Topics: Animals; Blepharoptosis; Blood Pressure; Chemistry, Organic; Drug Synergism; Electrocardiography; El | 1966 |
N-methyl-n-2-propynyl-l-indanamine. A protent monoamine oxidase inhibitor.
Topics: Animals; Behavior, Animal; Blepharoptosis; Chemistry, Organic; Drug Antagonism; Indenes; Mice; Monoa | 1966 |